To investigate the mechanism on which the clinical effectiveness of BP is based, we examined its effects on COX-2 expression and its major product, prostaglandin (PG)E(2), under conditions of inflammation. [ncbi.nlm.nih.gov]

Cape Verde, Caroline Is., Chagos Archipelago, Cook Is., Cyprus, Egypt, Fiji, Gabon, Gilbert Is., Gulf of Guinea Is., India, Kazan-retto, Laos, Libya, Line Is., Madagascar, Madeira, Malaya, Maldives, Marianas, Marshall Is., Mauritania, Mauritius, Morocco [plantsoftheworldonline.org]

Abstract Bidens pilosa L. var. radiata (BPR, Asteraceae) is a commonly used folk medicine for treating various disorders such as diabetes, inflammation and hypertension. [ncbi.nlm.nih.gov]

Abstract Bidens alba has been used for healing cuts, injuries, swellings, hypertension, jaundice, and diabetes in some countries. However, the effect of B. alba on human cancer remains poorly understood. [ncbi.nlm.nih.gov]

Most antioxidant compounds observed were developed in chloroform: ethyl acetate: formic acid and ethyl acetate: methanol: water solvent systems. [ncbi.nlm.nih.gov]

KEY FINDINGS: We observed that IL-8, TNF-α and NO release of HUVEC incubated with sera from active Henoch-Schönlein purpura (HSP) was significantly increased. [ncbi.nlm.nih.gov]

Finally, it did not show ocular irritation, as demonstrated by the effect on hemoglobin denaturation. This study supports the health benefits of the ingestion of the infusion. [ncbi.nlm.nih.gov]

In addition, they also show antifungal activity against a range of pathogenic fungi such as Aspergillus terreus (MIC 26.03 microM for botryorhodine A and 49.70 microM for B) and the plant pathogen Fusarium oxysporum (MIC 191.60 microM for botryorhodine [ncbi.nlm.nih.gov]

The crude ethanol extracts (whole plant, leaves and roots) and the chloroform and butanol fractions from B. pilosa at concentrations of 50 microg/ml caused up to 90% inhibition of Plasmodium falciparum growth in vitro. [ncbi.nlm.nih.gov]

MTT assay was used to investigate the inhibitory effect of different concentrations of the extracts on human hepatocellular carcinoma (HepG2) cell lines and human cervical carcinoma (Hela) cell lines, and the IC50 values were calculated. [ncbi.nlm.nih.gov]