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Bilateral Leg Weakness


Presentation

  • Spinal cord lesions: Upper motor neuron signs, sphincter dysfunction, and autonomic dysfunction may be present. A sensory level or loss of specific reflexes may help determine the segmental level the lesion.[sites.google.com]
  • A 35-year-old woman presented with one month's history of progressive bilateral leg weakness and altered sensation. There had been no pain. She had noted urinary frequency and constipation in the previous two weeks.[ncbi.nlm.nih.gov]
  • A description and images are presented, followed by the diagnosis and an explanation of how the diagnosis was determined. As always, your comments are welcome via email at pedann@Healio.com.[healio.com]
  • Jasmin A Jones MAcOM LAc LMT February 2013 OVERVIEW 42-year-old female presents with an inability to walk due to slow-onset, partial bilateral leg paralysis occurring over a 15 year time span.[acupuncturereliefproject.org]
  • Jankovic is the recipient of many other honors including the American Academy of Neurology (AAN) Movement Disorders Research Award, sponsored by the Parkinson’s Disease Foundation, the Guthrie Family Humanitarian Award, presented by the Huntington’s Disease[books.google.de]
Vietnamese
  • Paul's Top 5 Vietnamese Eateries Craving Vietnamese food? St. Paul has many spots that should satisfy your hunger.[minnesota.cbslocal.com]
Loss of Initiative
  • Motivation/Initiative 0 — Normal 1 —Less assertive than usual: more passive. 2 Loss of initiative or disinterest in elective (non-routine) activities. 3 — Loss... ‎[books.google.de]
Hypomimia
  • Facial Expression: 0 — Normal. 1 — Minimal hypomimia, could be normal "poker face. ‎[books.google.de]
Polyradiculoneuropathy
  • Brachial and lumbar plexuses in chronic inflammatory demyelinating polyradiculoneuropathy: MRI assessment including apparent diffusion coefficient. Neuroradiology . 2011;53:3–11. doi:10.1007/s00234-010-0684-7 [CrossRef][healio.com]

Workup

  • Workup If spinal cord disease is in the differential, an MRI of the cord is essential and should be done emergently. An LP is helpful in neuropathies and in spinal cord disease.[pedclerk.bsd.uchicago.edu]

Treatment

  • Patient reports she had treatment from a Korean medical practitioner, which ended 30 days prior to beginning treatment at the Vajra Varahi Medical Clinic.[acupuncturereliefproject.org]
  • If our patient had had an ESR or CRP test earlier, or if further imaging had been conducted sooner (given her proximal muscle weakness), the correct diagnosis would have been made more quickly and appropriate treatment provided sooner.[mdedge.com]
  • Early diagnosis of CIDP with early treatment can prevent loss of nerve axons. It is very difficult to implicate with certainty an etiologic role for a preceding vaccine in a patient who develops a polyneuropathy.[healio.com]
  • Treatment for foot drop will depend on the cause. Early treatment may improve chances of recovery. Treatments may include: lightweight braces shoe inserts (orthotics) physical therapy surgery Lightweight braces are the most common treatment.[webmd.com]
  • See Stiff Neck Causes, Symptoms, and Treatment Treatment of cervical radiculopathy Treatment for cervical radiculopathy typically needs to be tailored toward the specific underlying cause of your symptoms.[spine-health.com]

Prognosis

  • […] neurologic deficits. 1,2 Acute low back pain is often mechanical (97%); however, other causes, including infection, may be to blame ( TABLE ). 1 Most acute back pain will improve with conservative treatment and patients need only reassurance of a favorable prognosis[mdedge.com]
  • TCM DX: Kidney yang deficiency, cold stagnating the DU channel PROGNOSIS: Due to the fact that she has been untreated for 12 years, it is unlikely this patient will fully recover from acupuncture alone.[acupuncturereliefproject.org]
  • This cautious approach is understandable, given the prognosis of the illness and the devastation that being given the diagnosis may cause to a person's life.[patient.info]
  • Prognosis, sequelae, diagnosis, differential diagnosis, especially when the patient supine.[smj.org.sa]
  • Other immunosuppressive therapies such as cyclophosphamide, cyclosporine, and azathioprine have been tried with variable response but there are no double-blind, randomized, placebo-controlled studies to support the use of these medications. 4 The prognosis[n.neurology.org]

Etiology

  • It is very difficult to implicate with certainty an etiologic role for a preceding vaccine in a patient who develops a polyneuropathy. In this case, we can not be certain that influenza vaccination was the cause of the polyneuropathy.[healio.com]
  • Introduction Neurologists focus on identifying the location of the pathologic lesion as the first step in determining etiology.[pedclerk.bsd.uchicago.edu]
  • Other etiologies are less likely because of the absence of systemic symptoms, toxin exposure, or prior medical history, but still need to be ruled out as neuropathy can be the first or only manifestation of these conditions.[n.neurology.org]

Epidemiology

  • There may be several causes for such oxidative damage to motor neurons and the disease may just represent an end-stage phenotypic expression of these abnormalities. [ 4 ] Epidemiology MND is relatively uncommon with an annual incidence of about 2 cases[patient.info]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology This is a degenerative condition that affects motor neurons, namely the anterior horn cells of the spinal cord and the motor cranial nuclei.[patient.info]

Prevention

  • Early diagnosis of CIDP with early treatment can prevent loss of nerve axons. It is very difficult to implicate with certainty an etiologic role for a preceding vaccine in a patient who develops a polyneuropathy.[healio.com]
  • .: Prevention of hip fracture in elderly people with use of a hip protector. ‎[books.google.de]
  • Other treatments in the hospital focus on preventing complications.[medlineplus.gov]
  • Health benefits of corn include diabetes management, and prevention of heart con... Check it out, Arepa Café has been featured in Narcity! “They Serves Up ... Watercress is a dark, leafy green grown in natural spring water. For the past fe...[arepacafe.ca]
  • Including ketamine, the cunningham technique to prevent misinterpretation of the pediatric emergency medicine 316 burns with any sedative medication.[smj.org.sa]

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