Presentation
The other patient with bilateral frontal PMG presented seizures associated with photosensitivity and paroxysmal episodes of "alternating hemiplegia". [moh-it.pure.elsevier.com]
ORPHA:101070 Synonym(s): - Prevalence: - Inheritance: - Age of onset: - ICD-10: Q04.3 OMIM: 606854 UMLS: C1847352 MeSH: - GARD: 10784 MedDRA: - The documents contained in this web site are presented for information purposes only. [orpha.net]
A history of febrile seizures was present in 11.5% of participants. Further details regarding epilepsy localization and seizure semiology are presented in Table 1. [ncbi.nlm.nih.gov]
This led to the identification of patients presenting with less severe symptoms than previously described. [scielo.br]
Skin
- Photosensitivity
The other patient with bilateral frontal PMG presented seizures associated with photosensitivity and paroxysmal episodes of "alternating hemiplegia". [moh-it.pure.elsevier.com]
Treatment
Treatment and prognosis No specific treatment of polymicrogyria per se is available. Treatment is symptomatic and particularly aimed at controlling epilepsy, a common sequela. Related Radiopaedia articles Promoted articles (advertising) [radiopaedia.org]
The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. [orpha.net]
There is no specific treatment to get rid of this condition, but there are medications that can control the symptoms such as seizures, delayed development or weakened muscles as some of the noted effects. [en.wikipedia.org]
Prognosis
Treatment and prognosis No specific treatment of polymicrogyria per se is available. Treatment is symptomatic and particularly aimed at controlling epilepsy, a common sequela. Related Radiopaedia articles Promoted articles (advertising) [radiopaedia.org]
Though it is difficult to make a predictable prognosis for children with the diagnosis of PMG, there are some generalized clinical findings according to the areas of the brain that are affected. [en.wikipedia.org]
Etiology
Malformations of cortical development (MCD) can be defined as derangements in the development of the neocortex associated with a range of morphologic features and with multiple putative etiologic factors, including genetic and environmental influences [scielo.br]
Individuals with PMG reported to have been caused by cytomegalovirus or other acquired etiologies were also excluded. [ncbi.nlm.nih.gov]