Presentation
On Admission POA Help "Present On Admission" is defined as present at the time the order for inpatient admission occurs — conditions that develop during an outpatient encounter, including emergency department, observation, or outpatient surgery, are [icd10data.com]
We describe a 14-year-old boy who presents with a history of dysuria and some blood in his pants. Urinalysis showed no hematuria but persistent heavy proteinuria. [sjkdt.org]
Written by leading pathologists, this second edition presents an up-to-date, concise presentation of major pathological, clinical, pathophysiological, and genetic information for over 240 diagnoses. [books.google.com]
Entire Body System
- Enuresis
One patient presented in infancy (10 days of age), the others between 12.8 and 14.5 years (mean 13.7 years), with long-standing polydipsia and polyuria, enuresis, and growth retardation. [read.qxmd.com]
Respiratoric
- Tachypnea
He was admitted immediately after birth because of tachypnea and multiple anomalies, i. e., cleft lip, cleft palate, lowset and malformed ear, and retentio testis. [ci.nii.ac.jp]
Eyes
- Antimongoloid Slant
In addition, the two patients had similar multiple anomalies; microcephaly, prominent glabella, hypertelorism, antimongoloid slant, epicanthal folds, broad nose, cleft lip and palate, down-turned mouth, short philtrum, micrognathia, low set ears, hypospadias [ncbi.nlm.nih.gov]
In addition, the two patients had similar multiple anomalies; microcephaly, prominent glabella, hypertelorism, antimongoloid slant, epicanthal folds, broad nose, cleft lip and palate, downturned mouth, short philtrum, micrognathia, low set ears, hypospadias [onlinelibrary.wiley.com]
Psychiatrical
- Suggestibility
The suggested mechanism is a renal vascular insult, late in the pregnancy, as the precipitating event. [ncbi.nlm.nih.gov]
Kusuyama et al. first suggested that oligomeganephronia might be associated with a chromosomal anomaly, namely 4p monosomy syndrome. [tandfonline.com]
Workup
X-Ray
- Bilateral Small Kidneys
Fuke et al. reported the fourth case of OMN in the scientific literature. 2 They investigated a 23 year-old man who had hypertension, moderate renal insufficiency, persistent proteinuria and bilateral small kidneys. [scielo.br]
Treatment
The goal of treatment for Oligomeganephronic Renal Hypoplasia is to slow the progression of disease. [dovemed.com]
Signs and Symptoms of Oligomeganephronia Low birth weight Hypoosmolar urine, maximum gravity of urine is 1.007–1.012 Thirst, vomiting and dehydration Proteinuria End-stage renal disease around the age of 10 years Treatment of Oligomeganephronia Treatment [urology-textbook.com]
The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. [orpha.net]
[…] indication for second-line immunosuppressive treatment. [cmej.org.za]
Prognosis
Prognosis With the increasing metabolic demands on the kidney during growth, a decline in renal function is seen resulting in chronic renal failure at a mean age of 10 years (range 6 months to 20 years). Last updated: 10/9/2014 [rarediseases.info.nih.gov]
(Outcomes/Resolutions) The prognosis of Oligomeganephronic Renal Hypoplasia is dependent upon the severity of the signs and symptoms and associated complications, if any The condition is progressive. [dovemed.com]
Steroid Responsive NS : Good prognosis ( MCNS ) Steroid Resistant NS : Poor prognosis ( FSGS ) 30 Congenital Nephrotic Syndrome Presents in first 3 months of life Anasarca, hypoalbuminaemia, oliguria { Finnish’ Type } Antenatally detectable : – Raised [slideplayer.com]
Prognosis With the increasing metabolic demands on the kidney during growth, a decline in renal function is seen resulting in chronic renal failure at a mean age of 10 years (range 6 months to 20 years). [orpha.net]
Cystitis Tests o Home Kidney Tests o Home Urine Protein Tests (Kidney Function) o Home Prostate Cancer Tests * Kidney Health: Home Testing: o Home Microalbumin Tests (Kidney) o Home Urine Protein Tests (Kidney) o Home Urinary Tract Infection (UTI) Tests Prognosis [checkorphan.org]
Etiology
Oligomeganephronia, characterized clinically be early renal failure and histologically by large, sparse glomeruli, is of undetermined etiology. [ncbi.nlm.nih.gov]
TERMINOLOGY Abbreviations Oligomeganephronia (OMN) Synonyms Oligomeganephronic hypoplasia Definitions Renal hypoplasia with marked compensatory nephron hypertrophy occurring both sporadically and due to specific genetic disorders ETIOLOGY/PATHOGENESIS [basicmedicalkey.com]
Etiology The etiology of oligomeganephronia is not fully understood, but is hypothesized to be caused by premature termination of nephrogenesis. [rarediseases.info.nih.gov]
This is the first documented report of an intrauterine fetal demise of one twin in association with oligomeganephronia in the other, and suggests that these two conditions may be related etiologically. [karger.com]
Epidemiology
Epidemiology Prevalence is unknown. The male to female ratio is of 3:1. Clinical description Oligomeganephronia is usually detected on routine ultrasound screening with small but normal shaped kidneys. Birth weight is often below the average value. [rarediseases.info.nih.gov]
Summary Epidemiology Prevalence is unknown. The male to female ratio is of 3:1. Clinical description Oligomeganephronia is usually detected on routine ultrasound screening with small but normal shaped kidneys. [orpha.net]
Epidemiology Frequency United States Exact frequency of oligomeganephronia is difficult to determine. [emedicine.medscape.com]
Pathophysiology
Written by leading pathologists, this second edition presents an up-to-date, concise presentation of major pathological, clinical, pathophysiological, and genetic information for over 240 diagnoses. [books.google.com]
Learning objectives• Filtration barrier• Pathophysiology of FSGS• Genetics of FSGS• Management of FSGS• Recurrence of FSGS in Graft• Management of Recurrence 3. Glomerular Filtration Barrier 4. [slideshare.net]
Pathophysiology Oligomeganephronia results from arrested development of the metanephric blastema at 14-20 weeks' gestation, with subsequent hypertrophy of glomeruli and tubules in the kidney. [emedicine.medscape.com]
( Drug induced ) – Penicillamine, Gold, NSAIDS, Pamidronate, Mercury, Lithium 9 Idiopathic Minimal Change disease ( >80 % ) Mesangial proliferation Focal segmental Glomerulosclerosis Membranous Nephropathy Membranoproliferative glomerulonephritis 10 Pathophysiology [slideplayer.com]
Prevention
Prevention - Oligomeganephrony Not supplied. [checkorphan.org]
Prenatal testing is another possibility for prevention or awareness, and this can be done through molecular genetic testing or ultrasounds at later stages of pregnancy. [en.wikipedia.org]
• Galactose: Block the binding site or change the configuration of the free soluble factor, preventing it from binding to the podocytes• Podocyte stem cells therapy [slideshare.net]
Normal assent of these fused kidneys is prevented because they are caught by the root of the inferior mesenteric artery. Usually asymptomatic because its collecting system develops normally and the ureters enter the bladder. [authorstream.com]