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Biliary Duct Obstruction

Biliary Obstruction and Injury


Presentation

  • IBD (the vast majority being ulcerative colitis) is present in 60-80% of patients with PSC, and PSC is found in approximately 3% of patients with ulcerative colitis.[emedicine.medscape.com]
Physician
  • Am Fam Physician. 2000 Mar 15. 61(6):1673-80, 1687-8. [Medline]. American Society of Gastrointestinal Endoscopy. Technology status evaluation: magnetic resonance pancreatography. American Society of Gastrointestinal Endoscopy Clinical Guidelines.[emedicine.medscape.com]

Workup

Fasciola Hepatica
  • Eggs of certain liver flukes (eg, Clonorchis sinensis, Fasciola hepatica ) can obstruct the smaller bile ducts within the liver, resulting in intraductal cholestasis.[emedicine.medscape.com]

Treatment

  • A novel double stent system for palliative treatment of malignant extrahepatic biliary obstructions: a pilot study. AJR Am J Roentgenol. 2011 Nov. 197(5):W942-7. [Medline]. Fukasawa M, Takano S, Shindo H, Takahashi E, Sato T, Enomoto N.[emedicine.medscape.com]

Prognosis

  • Prognosis The prognosis as well as the mortality and morbidity of biliary obstruction depends on the cause. Complications Note the following: The complications of cholestasis are proportional to the duration and intensity of the jaundice.[emedicine.medscape.com]

Etiology

  • The etiology of this disorder in patients who are HIV-positive is thought to be infectious (cytomegalovirus, Cryptosporidium species, and microsporidia have been implicated).[emedicine.medscape.com]

Epidemiology

  • Epidemiology United States data The incidence of biliary obstruction is approximately 5 cases per 1000 people. Race-related demographics The racial predilection depends on the cause of the biliary obstruction.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • […] in the hepatodudoenal ligament and then courses through the head of the pancreas for approximately 2 cm; it joins the terminal part of the pancreatic duct to form the ampulla of Vater before passing through the papilla of Vater into the duodenum. [1] Pathophysiology[emedicine.medscape.com]

Prevention

  • Long-term relief of the biliary obstruction, whether it be surgical, percutaneous, or endoscopic, is necessary to prevent an adverse outcome. [5] Patients with biliary obstruction who undergo biliary tract surgery may develop postoperative acute oliguric[emedicine.medscape.com]

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