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2.1
Bismuth Subnitrate Poisoning
Bismuth Compound Poisoning

Presentation

Case presentation A 44-year-old woman presented to the emergency department with a two-week history of abnormal behaviour, decreased concentration and postural instability. [bmcneurol.biomedcentral.com]

Tannenbaum discusses a topic which again has engendered widespread interest amongst a large number of people, and where a balanced presentation of the relevant facts is particularly important. [books.google.com]

In this case report, we present of acute renal failure on account of colloidal bismuth subcitrate overdose in a 23-year-old young woman. [semanticscholar.org]

Evidence from Europe suggests SIBO may be present in ~50% of rosacea patients. [naturalmedicinejournal.com]

Entire Body System

  • Sepsis

    There was no evidence of bleeding, sepsis, or airway obstruction. A review of his medications showed that he only required tramadol 50mg once a day on average for analgesia from POD1 to POD6. [cureus.com]

Respiratoric

  • Postnasal Drip

    First, the placement of packing in the nasal and nasopharyngeal cavity allowed bismuth and iodine to enter the gastrointestinal tract via a postnasal drip. [cureus.com]

Liver, Gall & Pancreas

  • Asterixis

    He exhibited labile emotions and developed negative myoclonus in the form of asterixis in his upper limbs (see Video 1). There was no evidence of bleeding, sepsis, or airway obstruction. [cureus.com]

Skin

  • Foot Ulcer

    Suspected toxicity from an iodoform preparation in a diabetic patient with multiple foot ulcers. [cureus.com]

Neurologic

  • Altered Mental Status

    Our patient’s altered mental status may also have been aggravated by concomitant iodoform or iodine toxicity from the BIPP packing, as urinary iodine levels were high during the period of symptoms. [cureus.com]

    mental status, myoclonic jerks and ataxia [17, 19]. [bmcneurol.biomedcentral.com]

  • Basal Ganglia Hemorrhage

    ganglia hemorrhage, underwent endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma (NPC). [cureus.com]

  • Personality Change

    Jones et al. [1] in 1990 reported malaise, insomnia, personality change, and limb rigidity in a 79-year-old man after BIPP packing of the bony cavity following excision of a mandibular keratocyst. [cureus.com]

Workup

Other Pathologies

  • Diffuse Encephalopathy

    Electroencephalogram (EEG) showed severe diffuse encephalopathy (see Figure 2). Intoxication by either iodine or bismuth in the BIPP packs was suspected, and the BIPP packs were removed on POD7. [cureus.com]

Treatment

Abstract Bismuth compounds have been used over two centuries for the treatment of various gastrointestinal disorders due to their local protective, demulcent, and antacid properties. [link.springer.com]

[…] effect of the treatment should again be demonstrable. [docslide.net]

Treatment with the chelating agent dimercaptosuccinic acid… References SHOWING 1-10 OF 15 REFERENCES [semanticscholar.org]

Behavioural and biochemical changes after simultaneous and post-treatment of vitamin A and D on cadmium toxicity. Environ Toxicol Pharmacol. 1999;7(3):189–197. [ncbi.nlm.nih.gov]

Molina JA, Calandre L, Bermego F: Myoclonic encephalopathy due to bismuth salts: treatment with dimercaprol and analysis of CSF transmitters. Acta Neurol Scand. 1989;79:200–203. CrossRef [PubMed: 2566254] 32. [accesspharmacy.mhmedical.com]

Prognosis

This conference focused on the mechanisms underlying the condition and its diagnosis, treatment, prognosis, and associations with other conditions. [naturalmedicinejournal.com]

Etiology

Ali F. et al. [7] suggest a list of differential diagnoses: Creutzfeldt-Jakob disease and other neurodegenerative etiologies, other toxic/metabolic encephalopathy, neoplasms, infectious causes, vascular disorders, and systemic autoimmune disease with [bmcneurol.biomedcentral.com]

Epidemiology

His Scientific Publications are mainly on Toxicology and Epidemiology of environmental agents, particularly metals. [books.google.com]

Martin-Bouyer G, Foulon G, Guerbois H, Barin C: Epidemiological study of encephalopathies following bismuth administration per os. Characteristics of intoxicated subjects: comparison with a control group. Clin Toxicol. 1981;18:1277–1283. [accesspharmacy.mhmedical.com]

Epidemiological study of encephalopathies following bismuth administration per os. Characteristics of intoxicated subjects: comparison with a control group. Clin Toxicol. 1981;18(11):1277–83. Article CAS PubMed Google Scholar Bierer DW. [bmcneurol.biomedcentral.com]

Issues in Cancer Epidemiology and Research. p. 520. ISBN 978-1-4649-6352-0. ^ Greenwood, p. 553. ^ a b c d e f Godfrey, S. M.; McAuliffe, C. A.; Mackie, A. G.; Pritchard, R. G. (1998). Nicholas C. Norman (ed.). [en.wikipedia.org]

Pathophysiology

[…] full range of digestive complaints, along with systemic symptoms Most common underlying cause: absent or impaired migrating motor complex (MMC) Common causes/risk factors of SIBO: food poisoning, proton pump inhibitors (PPIs), and adhesions Primary pathophysiology [naturalmedicinejournal.com]

Background of the Invention Halitosis, or malodorous breath, is a common condition for which the exact pathophysiological mechanism remains unclear. It is generally assumed that malodorous compounds originate in the mouth. [google.sr]

Prevention

Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse [books.google.com]

Probiotics are likely preventive and therapeutic in many biofilms. Bismuth-thiol complex molecules can be effective in more advanced biofilms. [naturalmedicinejournal.com]

A paste impregnated gauze. a) Post ENT Surgical Procedures As an antiseptic gauze used to prevent infection and thus assist healing following ENT procedures. [imedi.co.uk]

In medicine, bismuth salts have been applied in combination with antibiotics for the treatment of Helicobacter pylori infections, for the prevention of diarrhea, and in radioimmunotherapy. [pubs.acs.org]

It thus prevents the action of the digestive secretions and of irritating foods or other substances on the mucous membrane. The same is true of its effect on the mucous membrane of the intestine. It is not absorbed in the stomach. [chestofbooks.com]

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