Presentation
Entire Body System
- Chronic Infection
Reactivation of BK virus in renal allografts causes a destructive chronic infection. [ncbi.nlm.nih.gov]
Gastrointestinal
- Chronic Diarrhea
Herein we describe the first case of BKV positive invasive urothelial carcinoma within the renal allograft, presenting with chronic diarrhea and weight loss 5 years following resolution of BK viremia/nephropathy (BKVN). [ncbi.nlm.nih.gov]
Workup
Serum
- Immunoglobulin A Decreased
Intravenous infusion of pooled immunoglobulins could decrease BK viral load in the plasma, as demonstrated in a small study of kidney transplant recipients. Randomized controlled studies are needed to determine efficacy. [infectiousdiseaseadvisor.com]
Microbiology
- Treponema Pallidum
The donors fulfilled all criteria required for blood donation, including serologic and PCR negativity for hepatitis B virus (HBV), hepatitis C virus (HCV), HIV, and Treponema pallidum Polyomavirus molecular diagnostic assays BKV and JCV loads were quantified [doi.org]
Other Pathologies
- White Matter Lesions
Brain magnetic resonance image revealed a new white matter lesion in the splenium. On immunohistochemistry, there was SV40-positive staining in gastric and heart biopsy specimens. [ncbi.nlm.nih.gov]