To the Editor: Bolivian hemorrhagic fever (BHF) was first described in 1959 during outbreaks affecting isolated human communities in eastern Bolivia. [dx.doi.org]

Bolivian hemorrhagic fever (BHF), also known as black typhus or Ordog Fever, is a hemorrhagic fever and zoonotic infectious disease originating in Bolivia after infection by Machupo mammarenavirus.BHF was first identified in 1963 as an ambisense RNA virus [en.wikipedia.org]

fever. ( 5301560 ) Johnson K.M....Valverde L. 1967 24 Bolivian hemorrhagic fever. [malacards.org]

The infection has_symptom fever, has_symptom headache, has_symptom fatigue, has_symptom myalgia, has_symptom arthralgia, has_symptom bleeding from the oral and nasal mucosa, and has_symptom bleeding from the bronchopulmonary, gastrointestinal and genitourinary [amp.pharm.mssm.edu]

Symptoms: Preliminary symptoms of Bolivian hemorrhagic fever caused by the Machupo virus include fever, headache, fatigue, myalgia, and arthralgia. [stanford.edu]

Following an incubation period of 1-2 weeks, patients infected with Machupo virus may develop an influenza-like illness with fever, malaise, and fatigue followed by the onset of headache, dizziness, myalgias, and severe lower back pain. [cdc.gov]

Early clinical manifestations in humans are characterized by nonspecific signs and symptoms including fever, headache, fatigue, myalgia, and arthralgia. [wwwnc.cdc.gov]

Bolivians referred to the mysterious disease as “Black Typhus” alluding to the hemorrhaging, high fever, pain, and rapid death caused by the illness. [stanford.edu]

The illness was characterized by high fever, headache, and bleeding from the nose, ears, and mouth, accompanied by jaundice, severe abdominal and thoracic pain as well as acute neurological manifestations. [johnhawks.net]

[…] of unknown origin [FUO] Fever with chills Fever with rigors Hyperpyrexia NOS Persistent fever Pyrexia NOS hemorrhagic (arthropod-borne) A94 ICD-10-CM Diagnosis Code A94 Unspecified arthropod-borne viral fever 2016 2017 2018 2019 Billable/Specific Code [icd10data.com]

Kyasanur Forest disease – Sudden onset of fever, chills, headache, severe prostration, arthralgia, generalized lymphadenopathy, myalgia, and facial flushing, followed in 72 hours by nausea, vomiting, diarrhea, and hemorrhage. [visualdx.com]

Hypotension may also have been due to decreased plasma protein synthesis. Copyright 1978 by The American Society of Tropical Medicine and Hygiene Article metrics loading... [ajtmh.org]

As the disease progresses, hypotension, dehydration, bradycardia, pulmonary edema, and internal hemorrhage may occur. The mortality rate may reach 30%; pulmonary edema is the most common cause of death. There is no specific therapy. [medical-dictionary.thefreedictionary.com]

From July 4 through August 12, 1994, seven family members (aged 10 months-50 years) developed an illness characterized by fever, hypotension, subconjunctival and gingival bleeding, epistaxis, petechiae, tremor, and dysarthria. [cdc.gov]

Early signs of infection include fever, hypotension, relative bradycardia, tachypnea, conjunctivitis, and pharyngitis. Some patients may have an accompanying rash. [visualdx.com]

Some initial symptoms caused by infection of the virus include fever, mild hypertension, headache, bleeding gums, and fatigue. [microbewiki.kenyon.edu]

Initial symptoms may include conjunctival injection, mild hypertension, flushing, bleeding gums and cavities, headache, arthralgia, and petechial haemorrhages. [phac-aspc.gc.ca]

Hemorrhagic and neurologic symptoms, including petechiae and bleeding gums, tremors, and lethargy are common. [journals.plos.org]

When first seen by the attending physicians, he had fever, thrombocytopenia, leukopenia, petechias, tremors, gingivorrhagia, and dehydration, consistent with symptoms of BHF. [dx.doi.org]

Petechiae (blood spots) on the upper body and bleeding from the nose and gums are observed when the disease progresses to the hemorrhagic phase, usually within seven days of onset. [en.wikipedia.org]

Flaviviridae Yellow fever – Facial flushing, conjunctival redness, and prominent low back pain in conjunction with the sudden onset of a flu-like illness. [visualdx.com]

The disease has typical ongoing set of symptoms, involving:fever, malaise, headache and body pain, blood spots, bleeding from the nose and gums( very similar to Ebola and Marburg too) and overall weakness,loss of appetite and vomiting, flushed face and [sarahmaxresearch.wordpress.com]

Initial symptoms may include conjunctival injection, mild hypertension, flushing, bleeding gums and cavities, headache, arthralgia, and petechial haemorrhages. [phac-aspc.gc.ca]

Pruritic skin lesions suggestive of S. scabiei mite infestation developed in 4 humans who had direct contact with affected farm animals but not foxes. [doi.org]

In the later stages of this illness, patients may develop hemorrhagic manifestations including subconjunctival hemorrhage, epistaxis, hematemesis, melena, and hematuria, as well as neurological signs including tremor, seizures, and coma. [ncbi.nlm.nih.gov]

From July 4 through August 12, 1994, seven family members (aged 10 months-50 years) developed an illness characterized by fever, hypotension, subconjunctival and gingival bleeding, epistaxis, petechiae, tremor, and dysarthria. [cdc.gov]

Advanced symptoms include mucous membrane haemorrhage, epistaxis, melena, and neurological damage such as tremors, seizures, loss of muscle control, and coma. Symptoms usually arise after a one week incubation period and generally last for one week. [microbewiki.kenyon.edu]

Symptoms can further develop into shock and generalized mucous membrane haemorrhage, epistaxis, haematemesis, melena, haematuria, accompanied by neurological damage such as tremor, seizures, and coma ( 4 ). [phac-aspc.gc.ca]

Initial symptoms include headache, fever, arthralgia, and myalgia. [ncbi.nlm.nih.gov]

The infection has_symptom fever, has_symptom headache, has_symptom fatigue, has_symptom myalgia, has_symptom arthralgia, has_symptom bleeding from the oral and nasal mucosa, and has_symptom bleeding from the bronchopulmonary, gastrointestinal and genitourinary [amp.pharm.mssm.edu]

After an incubation period of 1 to 2 weeks, the patient experiences chills, fever, headache, muscle ache, anorexia, nausea, and vomiting. [medical-dictionary.thefreedictionary.com]

The infection has a slow onset with fever, malaise, headache and myalgia, very similar to Malaria symptoms. [en.wikipedia.org]

The infection has a slow onset with fever, malaise, headache and muscular pains. [wikidoc.org]

When first seen by the attending physicians, he had fever, thrombocytopenia, leukopenia, petechias, tremors, gingivorrhagia, and dehydration, consistent with symptoms of BHF. [dx.doi.org]

In the later stages of this illness, patients may develop hemorrhagic manifestations including subconjunctival hemorrhage, epistaxis, hematemesis, melena, and hematuria, as well as neurological signs including tremor, seizures, and coma. [ncbi.nlm.nih.gov]

From July 4 through August 12, 1994, seven family members (aged 10 months-50 years) developed an illness characterized by fever, hypotension, subconjunctival and gingival bleeding, epistaxis, petechiae, tremor, and dysarthria. [cdc.gov]

Gross lesions included skin rash, lymphadenopathy, splenomegaly, meningeal edema, hydropericardium and enlarged friable livers. [ncbi.nlm.nih.gov]

A report of four cases. ( 4159195 ) Stinebaugh B.J....de Alba E. 1966 25 Detection of complement-fixing antibody after Bolivian hemorrhagic fever, employing Machupo, JunA-n and Tacaribe virus antigens. ( 5840640 ) Mackenzie R.B....Johnson K.M. 1965 [malacards.org]