Presentation
Abstract We present a rare case of delayed diagnosis of osteosarcoma of the medial clavicle in a young man. He presented following a pathological fracture with a falsely reassuring core and fine-needle aspiration biopsy. [ncbi.nlm.nih.gov]
Musculoskeletal
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Bone Disorder
Although bone specimens are usually decalcified for routine pathology to facilitate sample processing, when investigating metabolic bone disorders it is usually much more informative to analyse undecalcified samples. [ncbi.nlm.nih.gov]
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Severe Osteoporosis
On histomorphometric analysis, 3 specimens showed severe osteoporosis. In conclusion, iliac crest bone biopsy may need to be considered as an adjunct in screening for both unsuspected hematological disease and metabolic bone disease. [ncbi.nlm.nih.gov]
Psychiatrical
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Anger
Author information 1 Department of Bone Diseases, University Hospital, Angers Cedex, France. [ncbi.nlm.nih.gov]
Urogenital
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Kidney Failure
In addition, patients may have had underlying bone disease before developing kidney failure or may have been treated with agents that will alter the classical pathologic findings of the bones in chronic kidney disease and their relation to parathyroid [ncbi.nlm.nih.gov]
Neurologic
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Waddling Gait
Radiographs of the long bones of a 9-year-old boy presenting with waddling gait, muscular weakness, underweight, and severe skeletal pain showed symmetric diaphyseal cortical thickening pathognomonic for CED. [ncbi.nlm.nih.gov]
Workup
All specimen sampled were sufficient for histopathological workup. Compared to the historical cohort the time needed for biopsy decreased significantly from 13 6 to 6 4 min (P 0.0001). [ncbi.nlm.nih.gov]
X-Ray
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Nephrolithiasis
Primary hyperoxaluria is a rare congenital disorder characterized by large quantities of urinary oxalate with resultant nephrocalcinosis and nephrolithiasis and by deposits of calcium oxalate in other organs. Renal failure occurs early in life. [ncbi.nlm.nih.gov]
Microbiology
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Staphylococcus Aureus
Staphylococcus aureus was the commonest organism grown in both cultures. The bone pathogen was identified in the corresponding swab culture in only 55 cases (38.2%). [ncbi.nlm.nih.gov]
Biopsy
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Bone Biopsy Abnormal
All 14 patients who developed complications because of deep abscess and sinus tract formation had intraoperative Jamshidi core needle bone biopsy abnormality consistent with osteomyelitis (positive Jamshidi core needle bone biopsy results). [ncbi.nlm.nih.gov]
Treatment
In most cases (82/99), bone biopsy led to consequences in medical treatment. Following histopathological diagnosis, 16 patients did not receive any anti-osteoporotic treatment. [ncbi.nlm.nih.gov]
Prognosis
The definite diagnosis was established by bone biopsy, which revealed two totally unrelated disorders that altered the management and prognosis for these two patients. [ncbi.nlm.nih.gov]
[…] cells, which fight infections cancers of the blood, such as leukemia whether cancers that started elsewhere have spread to the bone marrow (the assessment of how much a cancer has spread is called staging, and is important in determining treatment and prognosis [kidshealth.org]
Etiology
The severe fracture history of these patients emphasizes the gravity of their bone disease and stresses the need for further study on the etiology and treatment of this form of osteoporosis. [ncbi.nlm.nih.gov]
[…] diabetic foot ulcers in an Indian tertiary care hospital, Diabetes Care, 2006, vol. 29 (pg. 1727 - 32 ) 24 Effect of bone biopsy in guiding antimicrobial therapy for osteomyelitis complicating open wounds, Am J Med Sci, 2001, vol. 321 (pg. 367 - 71 ) 25 Etiologic [academic.oup.com]
Epidemiology
Data bank registry can be a valuable tool to understand epidemiological aspects of MBD CKD. The Brazilian Registry of Bone Biopsy (REBRABO) will be a national registry, coordinating by the Brazilian Society of Nephrology - Committee of MBD-CKD. [ncbi.nlm.nih.gov]
Researchers from the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, used high resolution peripheral quantitative computed tomography (HRpQCT) to assess bone structure and strength at a microstructural level in living [sciencedaily.com]
Percutaneous bone biopsy is an undemanding and inexpensive way to induce better chances to cure the patient and to adequately manage the microbiological epidemiology. [woundsresearch.com]
Pathophysiology
This review will focus on recent insights into the pathophysiology of renal bone disease, as highlighted by bone biopsy, and discuss implications for treatment. [ncbi.nlm.nih.gov]
Prevention
Oral prednisolone was initiated, and subsequently, pamidronate infusions were commenced in an attempt to prevent progression of osteoporosis. [ncbi.nlm.nih.gov]
Avoiding sun exposure while taking tetracycline prevents skin photosensitivity. The patient should adhere strictly to the medication dosing and schedule to prevent problems in interpretation of the dynamic histomorphometry. [emedicine.medscape.com]