The clinical safety and possibility of immediate implant placement in aggressive periodontitis patients in maxillary esthetic zone: an empty systematic review Yussif N.M., Rahman A.R.A., Darhous M. [ccmbm.com]

The surface layer of the skin thickens and builds up, irritating the tissues underneath. Hard foot corns are usually located on the top of the toe or on the side of the small toe. [centralvapodiatry.com]

Callous (Definition) Callus is a noun meaning a localized thickening of the skin, and a verb meaning to form that skin thickening (especially on the palm of a hand or the sole of a foot, caused by repeated pressure or friction). [healthtap.com]

A skin thickening (see CALLOSITY ). callus a mass of immature plant cells which can differentiate into mature tissues, depending upon the relative concentrations of plant growth hormones present. [medical-dictionary.thefreedictionary.com]

Management Trimming of the hyperkeratosis to the central core, soaking (e.g., epsom salts), and shaved regularly; to redistribute weight-bearing, a full-sole orthotic, footwear change and a metatarsal pad or hammer-toe crest pad if needed. [medical-dictionary.thefreedictionary.com]

Teriparatide treatment for an atypical femoral fracture in a patient with calcinosis cutis associated with juvenile dermatomyositis: a case report Yoshitani J., Kabata T., Yamamoto N., Shimizu M., Kajino Y, Takagi T., Ohmori T., Ueno T., Tsuchiya H. [ccmbm.com]