Presentation
The pacient may present local pain, the appearance of local deformation due to a tumor mass or occurrence of pathological fractures. [ncbi.nlm.nih.gov]
Lesions may be asymptomatic and identified incidentally 50% of patients present with pathologic fracture, often due to minimal trauma Some patients present with swelling or stiffness of adjacent joint Physical findings Tender if fractured; fractures often [orthopaedicsone.com]
Musculoskeletal
- Bone Disorder
Differentiating Aneurysmal Bone Cyst from Other Diseases Aneurysmal bone cyst must be differentiated from following bone disorders: Epidemiology and Demographics ABC accounts for 1% to 2% of all primary bone tumors. [13] The incidence of aneurysmal bone [wikidoc.org]
Workup
It is therefore an integral part of the diagnostic workup when dealing with (myo)fibroblastic lesions of soft tissue and bone. Two cases of myositis ossificans with USP6 rearrangement were published so far. [ncbi.nlm.nih.gov]
Blood chemistry and metabolic workup are benign. [doi.org]
Treatment
Depending on the choice of treatment, a positive response occurs in 20 to 80 % of cases. These rates are unacceptable, particularly considering they concern the treatment of benign lesions affecting children. [ncbi.nlm.nih.gov]
En-block resection and reconstruction with strut grafting are the most common treatments and procedures that prevent recurrences of this type of cyst.Traumatic Bone Cyst The traumatic bone cyst treatment consists of surgical exploration, curettage of [en.wikipedia.org]
Prognosis
It is mandatory to distinguish ABC from UBC, as prognosis and treatment are different. UBCs resolve spontaneously between adolescence and adulthood; the main concern is the risk of pathologic fracture. [ncbi.nlm.nih.gov]
Wick: Unicameral bone cyst calcaneus Unicameral bone cyst, proximal humerus Xray AFIP images: Humerus Radiograph reveals untreated fracture Unicameral bone cyst Resected cyst from fibula Epiphysis of greater trochanter Prognostic factors Poorer prognosis [pathologyoutlines.com]
Often several years of active vigilance is necessary What is the Prognosis of Simple Bone Cyst? (Outcomes/Resolutions) The prognosis of a Simple Bone Cyst is usually excellent with accurate diagnosis and appropriate treatment. [dovemed.com]
Curettage and bone grafting, nailing, injection of bone marrow or cryotherapy to prevent pathologic fracture Methylprednisolone injections have been used to promote healing Complications Pathologic fractures in 50-65% Growth arrest in affected limb Prognosis [learningradiology.com]
Treatment and prognosis Intervention is usually not required for an asymptomatic lesion. If large and threatening to fracture, or causing deformity then an intralesional steroid injection can be performed 3, 4, 5. [radiopaedia.org]
Etiology
BACKGROUND: Jaw pseudocysts are benign osseous lesions of unclear etiology. Among these, the simple bone cyst (SBC) and aneurysmal bone cyst (ABC) are intriguing bone pathologies still rarely studied together. [ncbi.nlm.nih.gov]
These results may suggest that venous obstruction of the lesions play an important role in the etiology of multiple simple cysts, as shown in typical bone cysts. [link.springer.com]
Epidemiology
An aneurysmal bone cyst is an expansile osteolytic bony lesion composed of blood-filled spaces separated by connective tissue septa of bony trabeculae or osteoid tissue and osteoclast giant cells Epidemiology/Prevalence [ edit ] Almost always present [en.wikibooks.org]
Patient Population: Prevalence and Epidemiology Knee // Shoulder & Elbow // Hip // Spine // Foot & Ankle // Hand & Wrist Fragility Fractures: Diagnosis and Treatment Shoulder & Elbow The Characteristics of Surgeons Performing Total Shoulder Arthroplasty [amjorthopedics.com]
Epidemiology: UBCs account for 3% of all bone tumors. They commonly occur in patients age 4-10 years old (Herring, 2014). Males are twice as likely to have a UBC as females. [posna.org]
[…] misleading term because some of these lesions may consist of several multilocular cavities Definition typically a unilocular cystic lesion filled with serous fluid found in a major long bone in skeletally immature patients History First recognized by Virchow Epidemiology [orthofracs.com]
Epidemiology: - 85% of patients in the first decades of life. - Male:Female ratio 3:1. [pedorthpath.com]
Pathophysiology
This new hypothesis for SBC formation in non-load-bearing region for knee, which cannot be explained by the existing theories, will provide us a new angle to understand the pathomechanism and pathophysiology of subchondral bone disturbance in osteoarthritis [ncbi.nlm.nih.gov]
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Aneurysmal bone cyst (ABC) is a multicystic and expansile bone tumor of uncertain line of differentiation. [mayomedicallaboratories.com]
The true pathophysiology of ABCs is unknown. [13] Different theories about several vascular malformations exist; these include arteriovenous fistulas and venous blockage. [emedicine.medscape.com]
The true etiology and pathophysiology remain a mystery, but the mainstay of treatment has been intralesional curettage. Recurrence is not uncommon. [dx.doi.org]
Prevention
En-block resection and reconstruction with strut grafting are the most common treatments and procedures that prevent recurrences of this type of cyst.Traumatic Bone Cyst The traumatic bone cyst treatment consists of surgical exploration, curettage of [en.wikipedia.org]
To prevent increasing bone deformity and fragility, the deformity should be corrected as quickly as possible using intramedullary nailing or other fixation techniques. [ncbi.nlm.nih.gov]
The surgical treatment measures for Simple Bone Cyst may include the following: Aspiration of the fluid Injection of steroids into the cavity: Steroids help in prevention of re-accumulation of the cyst fluid; it also assists in filling-up of the cyst [dovemed.com]
In addition to identifying the cause of these cysts, research is also being done to better understand what might be done to prevent them. Research is also looking at better agents to inject into the cysts to prevent them from coming back. [orthoinfo.aaos.org]