Signs/Symptoms • Sometimes physical examination is unrevealing • Pathologic fracture may be the initial presentation. • When is symptomatic, may present discrete swelling near the affected area. • Cutaneous pigmentation (Café-au-lait spots) may be seen [tumorsurgery.org]

Pain is the most common presenting feature, accounting for 65% to 90% of the clinical presentation in some studies.2'6 Other possible presentations include swelling and pathologic fracture, though these occur in less than 20% of the patients.1,3,6,7 Trie [healio.com]

Case presentation We present the case of a 13-year-old Japanese boy with a complaint of discomfort in the thigh and a small, well-defined, osteolytic lesion with cortical thinning located in the medullary space of the distal diaphysis of the femur. [jmedicalcasereports.biomedcentral.com]

Lobulated areas; large pleomorphic cells may be present and get confused with chondrosarcoma (7). [arquivosdeorl.org.br]

The 6 cases presented here are not an exhaustive list of benign bone tumors but rather are examples of common lesions encountered in children. [consultant360.com]

• Bone Disorder

  Second most common bone disorder after osteoporosis. 70-90% of persons with Paget disease are asymptomatic. Study the images and then continue reading. [radiologyassistant.nl]

  If the bone looks weakened, however, your doctor may recommend that the tumor be surgically removed to avoid a fracture. Fibrous Dysplasia : In this uncommon genetic disorder, a fibrous tissue grows in place of part of the normal bone. [urmc.rochester.edu]

Therefore, any workup of a bone tumor should start with a good set of plain films. Age Patient age is a very important bit of knowledge to have in the workup of a tumor. [rad.washington.edu]

The fifth patient's tumor was also an incidental finding secondary to a workup for dysuria. [healio.com]

At Children’s Hospital of Philadelphia (CHOP), our clinical experts perform a careful and complete medical workup and examination of your child. [chop.edu]

At treatment the preparations appointed by the doctor, physical therapy and orthopedic devices are applied. If pain does not disappear or increases, there can be a need of surgical treatment. [herbalthera.com]

Treatment: Treatment requires surgery to remove the tumor. Outlook: Recurrences after curettage is common. [kucancercenter.org]

As they may have associated pathological fractures, treatment of the fracture is needed along with aspiration. Treatment with bone grafting also may be indicated. [pediatriceducation.org]

however, the defect may be supplemented with bone grafts or other stabilization techniques for frx prophylaxis and treatment Benign fibrous histiocytoma of bone Pathological fractures through non-ossifying fibromas. [wheelessonline.com]

Bisphosphonates have been used in the treatment of adults and may have a role in the treatment of severely affected children. Treatment with curettage and bone grafting often is unsuccessful. [consultant360.com]

The prognosis is good because malignant change and metastasis have not been reported. The authors are reporting a case of JPOF of the ethmoid bones with secondary ABC in a 7-year-old female patient. [ FULL TEXT ] [ PDF ]* [sjmms.net]

Prognosis: - Good. - Therapy ranges from observation to surgical removal. [pedorthpath.com]

Prognosis The prognosis is excellent. Cytogenetics Morphological Karyotypes of 12 cases are reported in the literature. Complex cytogenic abnormalities are reported. [atlasgeneticsoncology.org]

[…] increased activity can be seen during NOF "healing", corresponding to mild hyperaemia and osteoblastic activity note that extensive uptake or hyperaemia should prompt consideration of alternative diagnosis or a superimposed fracture 4 Treatment and prognosis [radiopaedia.org]

Genetic testing may be indicated for the evaluation of polyostotic bone lesions secondary to syndromic etiologies. References Levine SM, Lambaise RE, Petchprapa CN. [jaocr.org]

Aneurysmal bone cysts (ABC) are benign expansile tumor-like bone lesions of uncertain etiology, composed of numerous blood-filled channels, and mostly diagnosed in children and adolescents. [radiopaedia.org]

Controversy continues regarding the correct terminology and etiology of these lesions. The distinction between FCD and fibroxanthoma is based on size and natural history. [emedicine.medscape.com]

Etiology The exact cause is unknown, but the age and location distribution implicate the growing physis as the affected mechanism. [orthopaedicsone.com]

There was no prior history of trauma or any other etiology, which could contribute to the pathology of the lesion. [ispub.com]

Epidemiology: - 85% of patients in the first decades of life. - Male:Female ratio 3:1. [pedorthpath.com]

[…] can indicate the presence of Jaffe-Campanacci syndrome which can have the following findings: Multiple giant NOF Café-au-lait spots Multiple nevi Other irregular pigmentations Mental retardation Hypogonadism Occular and cardiovascular abnormalities Epidemiology [orthopaedicsone.com]

Epidemiology Chondromyxoid fibroma is a very rare neoplasm accounting for less than 1% of all bone tumours, and less of 2% of all benign bone tumours. [atlasgeneticsoncology.org]

Eyre R, Feltbower RG, James PW, et al ; The epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - BMC Cancer. 2010 Jul 610:357. [patient.info]

[…] a benign fibrogenic lesion that is the most common benign bone tumor in childhood related to dysfunctional ossification other names metaphyseal fibrous defect nonosteogenic fibroma cortical desmoid fibrous cortical defect fibromatosis fibroxanthoma Epidemiology [orthobullets.com]

Pathology and pathophysiology The gross pathology is soft tan fibrous tissue. Microscopically, there are spindled fibroblasts in a dense collagen background. [orthopaedicsone.com]

[…] demographics common in children 5-15 years old 30% of children with open physis have a NOF locations metaphysis of long bones 80% in lower extremity distal femur > proximal tibia > proximal fibula > distal tibia uncommon in proximal femur, proximal humerus Pathophysiology [orthobullets.com]

Over the past two decades, antiviral medications have been developed to help prevent outbreaks and speed healing... Read Article [marvistadentistry.com]

Risk factors and prevention There are no particular risk factors for development of a solitary lesion. Treatment options The natural history of the lesion is spontaneous resolution with no symptoms. [orthopaedicsone.com]

This is a minor procedure which helps prevent future fractures. Eventually, the bone graft is converted by the body to bone. [sarcoma.md]

It is also prescribed after surgery to kill any remaining cancer cells and prevent recurrence. [drhosalkar.com]

[…] marrow Diseases of the different cell types Cell types and functions: White blood cells (WBCs) WBCs are of five different types: lymphocytes neutrophils (also called granulocytes) eosinophils basophils monocytes These play different roles in infection prevention [news-medical.net]