Signs/Symptoms • Sometimes physical examination is unrevealing • Pathologic fracture may be the initial presentation. • When is symptomatic, may present discrete swelling near the affected area. • Cutaneous pigmentation (Café-au-lait spots) may be seen [tumorsurgery.org]

Pain is the most common presenting feature, accounting for 65% to 90% of the clinical presentation in some studies.2'6 Other possible presentations include swelling and pathologic fracture, though these occur in less than 20% of the patients.1,3,6,7 Trie [healio.com]

Case presentation We present the case of a 13-year-old Japanese boy with a complaint of discomfort in the thigh and a small, well-defined, osteolytic lesion with cortical thinning located in the medullary space of the distal diaphysis of the femur. [jmedicalcasereports.biomedcentral.com]

Lobulated areas; large pleomorphic cells may be present and get confused with chondrosarcoma (7). [arquivosdeorl.org.br]

The most common presenting symptom is pain and/or swelling, although pathologic fracture has been described previously as a common reason for seeking treatment. This tumor has also presented as an incidental finding [2]. [faoj.org]

The fifth patient's tumor was also an incidental finding secondary to a workup for dysuria. [healio.com]

Therefore, any workup of a bone tumor should start with a good set of plain films. Age Patient age is a very important bit of knowledge to have in the workup of a tumor. [rad.washington.edu]

At Children’s Hospital of Philadelphia (CHOP), our clinical experts perform a careful and complete medical workup and examination of your child. [chop.edu]

At treatment the preparations appointed by the doctor, physical therapy and orthopedic devices are applied. If pain does not disappear or increases, there can be a need of surgical treatment. [herbalthera.com]

Treatment: Treatment requires surgery to remove the tumor. Outlook: Recurrences after curettage is common. [kucancercenter.org]

Treatment consists of complete surgical removal. However, incomplete excision has been associated with a high local recurrence rate. The prognosis is good because malignant change and metastasis have not been reported. [sjmms.net]

[…] to 70 years Some are indolent; some growth rapidly Sites: craniofacial skeleton (maxilla, mandible, paranasal sinuses); psammomatoid tumors usually don’t affect the jaw Incidental or symptoms of facial enlargement, nasal obstruction, pain, proptosis Treatment [pathologyoutlines.com]

The treatment of choice when confronted with this clinical and x-ray picture is bone biopsy, wide excision, and bone grafting [3,7]. Recurrent lesions can lead to selective amputation. [faoj.org]

The prognosis is good because malignant change and metastasis have not been reported. The authors are reporting a case of JPOF of the ethmoid bones with secondary ABC in a 7-year-old female patient. [ FULL TEXT ] [ PDF ]* [sjmms.net]

Prognosis The prognosis is excellent. Cytogenetics Morphological Karyotypes of 12 cases are reported in the literature. Complex cytogenic abnormalities are reported. [atlasgeneticsoncology.org]

PROGNOSIS Biological Behavior • Benign tumor, indolent and not active nor aggressive. • The tumor may be large enough to place the bone at risk for fracture (probably greater than 50% of the diameter of the bone in both directions). • When the patient [tumorsurgery.org]

Prognosis: - Good. - Therapy ranges from observation to surgical removal. [pedorthpath.com]

Genetic testing may be indicated for the evaluation of polyostotic bone lesions secondary to syndromic etiologies. References Levine SM, Lambaise RE, Petchprapa CN. [jaocr.org]

Controversy continues regarding the correct terminology and etiology of these lesions. The distinction between FCD and fibroxanthoma is based on size and natural history. [emedicine.medscape.com]

Etiology The exact cause is unknown, but the age and location distribution implicate the growing physis as the affected mechanism. [orthopaedicsone.com]

Aneurysmal bone cysts (ABC) are benign expansile tumor-like bone lesions of uncertain etiology, composed of numerous blood-filled channels, and mostly diagnosed in children and adolescents. [radiopaedia.org]

There was no prior history of trauma or any other etiology, which could contribute to the pathology of the lesion. [ispub.com]

Epidemiology Chondromyxoid fibroma is a very rare neoplasm accounting for less than 1% of all bone tumours, and less of 2% of all benign bone tumours. [atlasgeneticsoncology.org]

Epidemiology: - 85% of patients in the first decades of life. - Male:Female ratio 3:1. [pedorthpath.com]

[…] can indicate the presence of Jaffe-Campanacci syndrome which can have the following findings: Multiple giant NOF Café-au-lait spots Multiple nevi Other irregular pigmentations Mental retardation Hypogonadism Occular and cardiovascular abnormalities Epidemiology [orthopaedicsone.com]

Eyre R, Feltbower RG, James PW, et al ; The epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - BMC Cancer. 2010 Jul 610:357. [patient.info]

[…] a benign fibrogenic lesion that is the most common benign bone tumor in childhood related to dysfunctional ossification other names metaphyseal fibrous defect nonosteogenic fibroma cortical desmoid fibrous cortical defect fibromatosis fibroxanthoma Epidemiology [orthobullets.com]

Pathology and pathophysiology The gross pathology is soft tan fibrous tissue. Microscopically, there are spindled fibroblasts in a dense collagen background. [orthopaedicsone.com]

[…] demographics common in children 5-15 years old 30% of children with open physis have a NOF locations metaphysis of long bones 80% in lower extremity distal femur proximal tibia proximal fibula distal tibia uncommon in proximal femur, proximal humerus Pathophysiology [orthobullets.com]

Over the past two decades, antiviral medications have been developed to help prevent outbreaks and speed healing... Read Article [marvistadentistry.com]

Adequate excision is important in preventing possible recurrence. REFERENCES 1. Sugiura I. Desmoplastic fibroma: case report and review of the literature. J Bone Joint Surg. 1976; 58A:126-130. 2. Jaffe HL. [healio.com]

Risk factors and prevention There are no particular risk factors for development of a solitary lesion. Treatment options The natural history of the lesion is spontaneous resolution with no symptoms. [orthopaedicsone.com]

It is also prescribed after surgery to kill any remaining cancer cells and prevent recurrence. [drhosalkar.com]

This is a minor procedure which helps prevent future fractures. Eventually, the bone graft is converted by the body to bone. [sarcoma.md]