We herein present a case of other iatrogenic immunodeficiency-associated lymphoproliferative disorder (OIIA-LPD) presenting as PBL. A 63-year-old woman was diagnosed with rheumatoid arthritis and had been treated with methotrexate for seven years. [ncbi.nlm.nih.gov]

• Soft Tissue Mass

  No soft-tissue mass is seen. Figure 3b. Lytic pattern with well-defined margins. [dx.doi.org]

  The case for a diagnosis of primary bone lymphoma is further strengthened if the soft-tissue mass and marrow changes are associated with surprisingly little cortical destruction. [ncbi.nlm.nih.gov]

  Radiological imaging revealed a lytic destruction, periosteal reaction, and pathological fracture of radius and tibia with soft tissue mass. [journals.lww.com]

• Soft Tissue Swelling

  CT scan of left knee joint showed multiple lytic and sclerotic areas involving the lower end of left femur with adjacent soft tissue swelling [Figure 3] and [Figure 4]. [cancerjournal.net]

  CT revealed a lytic destruction of left tibia with swelling of surrounding soft tissues (Fig. 4). Also, periosteal reaction and pathological fracture could be found. [journals.lww.com]

  Pain at the local site and soft tissue swelling were the commonest symptoms. Involvement of the bones in the lower half of the body was more frequent than the bones in the upper half. [ijpmonline.org]

• Forearm Pain

  The patient was a 14-year-old girl with left forearm pain and swelling after trauma. Six months later after the last chemotherapy and radiotherapy, pain and swelling of left knee was presented. [ncbi.nlm.nih.gov]

  In this case report, we describe a male who presented with left-sided distal forearm pain, swelling of 2 months duration, and progressive limited wrist motion for about 1 month. The patient had no significant medical history except diabetes. [dovepress.com]

• Swelling of the Finger

  A 66-year-old woman presents with progressive bilateral swelling of her fingers, elbows, and toes. [ncbi.nlm.nih.gov]

• Elbow Pain

  (a) Plain radiograph of a 24-year-old man with right elbow pain shows a pathologic fracture through the markedly eroded ulna and extensive cortical breakthrough. A soft-tissue mass is also seen. [dx.doi.org]

  HCC, pneumonia) 13 F/63 Scapula shoulder mass 4 diffuse large B cell IIEA CEOP 4500 CR 19 12 alive 14 F/71 Ulna elbow pain 12 diffuse large B cell IIEA M-BACOP 5040 CR 28 20 alive 15 F/44 Femur knee pain, swelling 5 diffuse large B cell IEA M-BACOP [ncbi.nlm.nih.gov]

• Delayed Wound Healing

  Another patient with involvement of the fibular head experienced foot drop and delayed wound healing. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography revealed complete response to the treatment. [ncbi.nlm.nih.gov]

• Foot Drop

  Another patient with involvement of the fibular head experienced foot drop and delayed wound healing. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography revealed complete response to the treatment. [ncbi.nlm.nih.gov]

A positron emission tomography CT (PET-CT) performed as part of the staging workup revealed fluorodeoxyglucose avid lesions in the spine and left femur. [ncbi.nlm.nih.gov]

• Solitary Lytic Bone Lesion

  We have described the case of a 50-year-old female with a solitary lytic bone lesion with the penumbra sign involving the distal tibia. [synapse.koreamed.org]

• Bicytopenia

  We report a unique case of PBNHL with bicytopenia as the initial clinical manifestation in a Chinese. [caribbean.scielo.org]

• Hypercellular Bone Marrow

  Bone marrow aspiration showed hypercellular bone marrow consisting of 11.6% of small-sized lymphocytes with scant cytoplasm. [caribbean.scielo.org]

Bone lymphoma may show osteosclerotic and osteolytic CT patterns at diagnosis, during treatment, and after treatment. [ncbi.nlm.nih.gov]

Pediatric PBL-DLBCL has a favorable prognosis but remains poorly characterized. Herein, 10 such cases are detailed. They involved 11- to 20-year-old males with bone lesions that were often painful. [ncbi.nlm.nih.gov]

To exclude the effect of different histological type on prognosis, fewer studies have discussed the prognosis of PB-DLBCL alone and suggested that PB-DLBCL has a better prognosis than other types of DLBCL. [nature.com]

Certain subtypes of NHL have been shown to be associated with a virus (Epstein-Barr virus [EBV], human immunodeficiency virus [HIV], human herpes virus-6 [HHV-6]). [1] However, viral etiology has not been studied to any great extent in primary NHL of [emedicine.medscape.com]

High-risk groups includes those who have received an organ transplant or who have a suppressed immune system." [3] "Several possible etiologic mechanisms are hypothesized for NHL. [physio-pedia.com]

[…] lymphoma Primary bone lymphoma (PBL): defined as lymphoma presenting in an osseous site with no evidence of disease elsewhere for at least 6 months Presence of regional lymph nodes does not exclude the diagnosis of PBL ( Joint Bone Spine 2000;67:446 ) Epidemiology [pathologyoutlines.com]

(solitary site) most primary lymphomas of bone are Non-Hodgkin's B-cell lymphomas rather than T-cell variants diagnosed when there is only a single node of disease for six months multiple bony sites (no visceral sites) bone and soft tissue lymphoma Epidemiology [orthobullets.com]

The epidemiology of non-Hodgkin's lymphoma: comparison of nodal and extra-nodal sites. Int J Cancer 1997; 17: 923–30. 2. Conlan MG, Bast M, Armitage JO, Weisenburger DD. [caribbean.scielo.org]

[…] by lymphoma is more common than primary, considered to be stage IV Sites Any bone can be involved Usually sites of bone marrow, axial skeleton (spine), femur Common in metaphysis; presence in diaphysis or epiphysis probably means progressive disease Pathophysiology [pathologyoutlines.com]

Favorites PDF Get Content & Permissions Buy Editorial PDF Only Prostaglandins and the Pathophysiology of Esophagitis Rigas, Basil Journal of Clinical Gastroenterology. 21(4):266-267, December 1995. [journals.lww.com]

Although small numbers prevent firm conclusions, the inclusion of the whole bone or regional nodes in the irradiated volume did not appear to improve results. [ncbi.nlm.nih.gov]

[…] for plagiarism Yes Review by Single-blind Peer reviewers approved by Dr Ram Prasad Peer reviewer comments 2 Editor who approved publication: Dr William Cho Chen Tian, Yong Yu, Hongliang Yang, Lei Zhu, Yafei Wang, Yizhuo Zhang Key Laboratory of Cancer Prevention [dovepress.com]

Platelets help to clot the blood to prevent bleeding. These stem cells develop into red blood cells, white blood cells and platelets. How transplants work You have a stem cell transplant after very high doses of chemotherapy. [cancerresearchuk.org]

To utilize biological therapies to reverse illness, it is imperative to assist the body in the removal of these toxins to restore the immune system, which is known to play an active role in preventing and fighting cancer. [cancercompassalternateroute.com]

After that high dose chemoterapy is given to remove remaining cancer cells or to prevent relapses. These chemotherapies also remove blood producing cells left in bone marrow. [ankara.baskenthastaneleri.com]