Erlenmeyer flask deformity 41. 2-Other manifestations : -Spleen : -Massive splenomegaly -Splenic nodules -Splenic infarcts -Liver : -Hepatomegaly 42. c) Differential Diagnosis : -Erlenmeyer flask deformity, can be seen in : L CHONG 1-Lead poisoning 2- [slideshare.net]

For patients with easy bruising, vitamin E supplementation may exacerbate the symptom. [mitoaction.org]

Patients will commonly have lower white cell and platelet counts with the attendant symptoms of susceptibility to infection and easy bruising. Other symptoms of PNH may include back pain, abdominal pain, and liver failure. [marrowforums.org]

Thrombocytopenia - easy bruising, petechiae, bleeding from the nose and/or gums. Presence of hepatomegaly, splenomegaly or lymphadenopathy suggests a diagnosis of leukaemia. [patient.info]

Low blood cell counts, referred to as cytopenias, are a hallmark feature of MDS and are responsible for some of the symptoms that MDS patients experience — infection, anemia, spontaneous bleeding, or easy bruising. [mds-foundation.org]

RESULTS: The pattern of the time-intensity curve of patients with aplastic anemia showed a low peak value followed by a slow washout. [ncbi.nlm.nih.gov]

“Aplastic anemia may be congenital, or develop from Franconi anemia, an inherited disorder,” says Kassim. [everydayhealth.com]

Iron deficiency anemia is a common form of anemia when the body lacks sufficient red blood cells as a result of iron deficiency. There are several types of anemia. [mybiosource.com]

Audrey Nethery from Kentucky has Diamond Blackfan Anemia (DBA), a life-threatening bone marrow condition that impacts her body's ability to circulate oxygen. [dailymail.co.uk]

Anemia (RA), all types Renal Cell Carcinoma Retinoblastoma Rhabdomyosarcoma Severe Aplastic Anemia Severe Combined Immunodeficiency (SCID), all sub-types SCI Sickle Cell Disease Sly Syndrome (MPS VII) Thalassemia Wilms’ Tumor Wiskott-Aldrich Syndrome [bonemarrow.org]

Refractory anemia : There are too few red blood cells in the blood and the patient has anemia. The number of white blood cells and platelets is normal. [cancer.gov]

Finally, it may arise from lymphoproliferative diseases (eg, lymphomas, chronic lymphocytic leukemia) or collagen vascular diseases (eg, systemic lupus erythematosus, refractory anemia), or it may occur during pregnancy. [emedicine.medscape.com]

MDS: refractory anemia with excess blasts (RAEB), or chronic myelomonocyte leukemia (CMML). Myeloproliferative diseases associated with either cytopenia or uncontrolled proliferation. [clinicaltrials.gov]

These symptoms can include tenderness, tingling, numbness or a decrease in blood flow on the site of the tumor, causing a cold hand or foot with absent or weak pulses. Types of Bone Marrow disease: Bone marrow disease is serious disease. [homenaturalcures.com]

eyes or vision changes (signs of cGvHD of the eyes) Dry mouth, white patches inside the mouth, pain or sensitivity to spicy foods (signs of oral cGvHD, of the mouth) Shortness of breath or changes seen on your chest X-ray (signs of dry cough pulmonary [my.clevelandclinic.org]

You can also watch this super cute video of her singing “Rudolph The Red-Nosed Reindeer.” Dance on, Audrey. Dance on. You’ve got better rhythm than most of us. [dailydot.com]

dryness/ tightening, or penile dysfunction (signs of cGvHD of the genitourinary system, bladder, or sexual organs) [my.clevelandclinic.org]

Essential thrombocytosis (primary thrombocythemia): The body produces too many platelets, due to an unknown cause; the platelets do not work properly, resulting in excessive clotting, bleeding, or both. [webmd.com]

Essential thrombocythaemia (ET): A disease effecting the megakaryocytes resulting in a high platelet count (thrombocytosis). About half (50 per cent) of ET cases have the mutation of the Janus 2 kinase gene (JAK2 mutation). [labtestsonline.org.au]

Extramedullary hematopoiesis (production of blood cells in organs outside the bone marrow, such as the spleen and liver) Thrombosis and thrombohemorrhagic complications (blood clotting or bleeding complications) Leukocytosis (too many white blood cells) Thrombocytosis [mpnresearchfoundation.org]