CONCLUSION: The prevalence of B. pertussis in children presenting to the ED with bronchiolitis was 2%. Copyright 2011 Elsevier Inc. All rights reserved. [ncbi.nlm.nih.gov]

• Fever

  A38.0 Scarlet fever with otitis media A38.1 Scarlet fever with myocarditis A38.8 Scarlet fever with other complications Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes. [icd10data.com]

  Fever abated within 24 hours of instituting levofloxacin, and he was weaned off oxygen within 72 hours. [journals.lww.com]

  Though efficacious and immunogenic, tolerability was limited by vaccine reactions, including local reactions, fever, and febrile seizures. [medpagetoday.com]

  All whole cell vaccines are reactogenic, causing fever and local reactions in many vaccinees. In the past, these vaccines were thought to cause infant deaths and brain damage. [doi.org]

• Pediatric Disease

  We sought to compare pediatric disease caused by B. parapertussis to B. pertussis during the period from 2010-2015. Methods: Microbiology laboratory records were reviewed from 1984 to 2015 (Figure 1) to identify cases of pertussis and parapertussis. [idsa.confex.com]

  EPIDEMIOLOGY• Predominately a pediatric disease• Highest in the 1st year of life• Maternal antibodies are not protective.• Females suffers more than males.• World wide in distribution• Epidemics occurs periodically.• In early stage of infection droplets [de.slideshare.net]

• Fishing

  Proc Natl Acad Sci U S A. 1977 Dec; 74 (12):5463–5467. [ PMC free article ] [ PubMed ] [ Google Scholar ] Sekura RD, Fish F, Manclark CR, Meade B, Zhang YL. Pertussis toxin. Affinity purification of a new ADP-ribosyltransferase. [ncbi.nlm.nih.gov]

• Fatigue

  His symptoms had been slowly progressing over the preceding 6 months, with the additional development of fatigue and nonproductive cough 2–3 months before presentation, both of which had worsened in the past 2 weeks. [journals.lww.com]

• Cough

  Frequencies of typical symptoms of whooping cough, such as paroxysmal coughing, whooping and vomiting, were almost identical in the two groups. Nocturnal coughing and contact anamnesis were noted more often in the Bordetella pertussis group. [ncbi.nlm.nih.gov]

• Persistent Cough

  Pertussis, also known as whooping cough, is a respiratory infection that causes a persistent cough in all age groups from the newborn to the elderly. [ibl-international.com]

  cough, especially in the absence of fever, sore throat, hoarseness, tachypnea, or wheeze Posttussive emesis in setting of acute viral illness symptoms Laboratory Testing Refer to Key Points Differential Diagnosis Acute ( Viral upper respiratory infection [arupconsult.com]

  Pertussis can also present as a non-specific persistent cough Vomiting often follows a coughing spasm. Infants may develop apnoea and/or cyanosis with coughing spasms. Close contact with a case of Pertussis may raise suspicion. [rch.org.au]

• Flushing

  Flush a plastic catheter or tubing with 2-3 mL of saline. Insert the tubing into the nostril parallel to the palate. Aspirate nasopharyngeal secretions. Repeat this procedure for the other nostril. Combine aspirates into a sterile vial. [questdiagnostics.com]

• Sleep Disturbance

  Forty percent reported posttussive vomiting, 40% coryza, 32% apnea/sleep disturbance, and 12% sore throat. All were current with pertussis vaccination. [ncbi.nlm.nih.gov]

Prompt treatment might shorten illness duration, and prompt HHM prophylaxis might prevent secondary illnesses. [ncbi.nlm.nih.gov]

The results of this prospective study suggest that Bordetella parapertussis is a more common etiologic agent of mild respiratory tract infection among vaccinated school-aged children than is generally recognised. [ncbi.nlm.nih.gov]

[…] diagnostic test for the detection of Bordetella pertussis or Bordetella parapertussis Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Bordetella pertussis is the highly contagious etiological [mayocliniclabs.com]

Birkebaek NH: Bordetella pertussis in the etiology of chronic cough in adults.Diagnostic methods and clinic. Dan Med Bull 2001; 48:77–80. Wendelboe and Van Rie: Diagnosis of pertussis: a his- torical review and recent developments. [ijm.tums.ac.ir]

Specific diagnostic tools were applied for the first time in a Tunisian prospective study in order to get a first estimation of the prevalence of Bordetella pertussis/parapertussis infections and to evaluate their use to determine the epidemiologic characteristics [ncbi.nlm.nih.gov]

Epidemiology and Pathogenesis Epidemiology Before the introduction of the vaccine (and currently in nonimmunized populations), pertussis (whooping cough) periodically became an epidemic disease that cycled approximately every 2 to 5 years. [clinicalgate.com]

Overview of pertussis: focus on epidemiology, sources of infection, and long term protection after infant vaccination. Pediatric Infectious Disease Journal 2005 ; 24 : S104 – S108. 3. He, QS, et al. [cambridge.org]

Useful For Suggests clinical disorders or settings where the test may be helpful Preferred diagnostic test for the detection of Bordetella pertussis or Bordetella parapertussis Clinical Information Discusses physiology, pathophysiology, and general clinical [mayocliniclabs.com]

Prompt treatment might shorten illness duration, and prompt HHM prophylaxis might prevent secondary illnesses. [ncbi.nlm.nih.gov]

The B. parapertussis O-antigen thus serves a dual role of preventing vaccine antibodies from controlling B. parapertussis infection and enabling increased intracellular survival of B. parapertussis in macrophages. [epidemics.psu.edu]