Presentation
We present a very rare case of a patient with non-small-cell lung cancer and unilateral pleural effusion who presented BP infection. References [1] S. Mattoo, J.D. [archbronconeumol.org]
We report a 28-day-old female infant with pertussis presenting as severe acute bronchiolitis with cyanosis. On admission, the patient's symptoms were similar to those of acute bronchiolitis. [ncbi.nlm.nih.gov]
Pertussis IgG antibodies will be present in anyone who has been vaccinated. Pertussis IgM and IgA antibodies will usually only be present a short time after vaccination or infection. [labtestsonline.org.au]
Snapshot A 2-month-old girl infant presents to the emergency room with a 3-day history of a cough and post-tussive emesis. Her mother reports that while she had the Tdap vaccine during pregnancy, the father did not. [medbullets.com]
Most of the PCR tests are based on detection of insertion sequences (IS) present in multiple copies per genome, increasing the sensitivity of PCR tests. [certest.es]
Entire Body System
- Fever
Tick-borne Rickettsia rickettsii Rocky Mountain spotted fever Rickettsia conorii Boutonneuse fever Rickettsia japonica Japanese spotted fever Rickettsia sibirica North Asian tick typhus Rickettsia australis Queensland tick typhus Rickettsia honei Flinders [en.wikipedia.org]
It is caused by Bordetella pertussis ... pneumophila (Legionellosis)- Pontiac Fever and Legionnaires’ Disease Mycoplasma pneumoniae Infection Pertussis ... to diagnose pertussis. [arupconsult.com]
- Malaise
The first stage, colonization, is an upper respiratory disease with fever, malaise and coughing, which increases in intensity over about a 10-day period. [textbookofbacteriology.net]
The first stage causes upper respiratory ailments with fever, malaise, and coughing. The second stage begins gradually with a prolonged and paroxysmal cough that ends with the characteristic gasp, or whoop. [web.mst.edu]
The first stage is the catarrhal phase with symptoms of mild respiratory infection including malaise, conjunctivitis, nasal discharge, sore throat, dry cough and mild fever. This progresses after one or two weeks to the paroxysmal coughing stage. [patient.info]
View/Print Table TABLE 1 Stages of Pertussis Infection Stage Duration(weeks) Symptoms Comment Catarrhal One to two Lacrimation, low-grade fever, malaise, mild conjunctival inflammation, rhinorrhea, late-phase nonproductive cough Insidious onset Gradually [aafp.org]
- Low Fever
Symptomology is very similar to a traditional upper respiratory infection and includes mild coughing, low fever, and coryza. Individuals are most infectious during this stage. [pathwaymedicine.org]
The first stage, known as the catarrhal stage, mimics the common cold, and is classified by a runny nose, low fever, sneezing, and mild cough (4). [austincc.edu]
- Pediatric Disease
EPIDEMIOLOGY• Predominately a pediatric disease• Highest in the 1st year of life• Maternal antibodies are not protective.• Females suffers more than males.• World wide in distribution• Epidemics occurs periodically.• In early stage of infection droplets [slideshare.net]
- Infectious Mononucleosis
Cryptococcus neoformans as the infectious agent of invasive cryptococcal disease Cytomegalovirus Antibodies, ... infectious mononucleosis Order to detect EBV in individuals suspected of having EBV-related disease ... [arupconsult.com]
Respiratoric
- Pertussis
(CDC) Bordetella pertussis Whooping cough ( pertussis ) is caused by the bacterium Bordetella pertussis. B. pertussis is a very small Gram-negative aerobic coccobacillus that appears singly or in pairs. [textbookofbacteriology.net]
Antibody Stain Bordetella pertussis by PCR 0065078 Polymerase Chain Reaction Bordetella pertussis/parapertussis by PCR 0065080 Polymerase Chain Reaction Bordetella pertussis Antibodies, IgG & IgM 0050801 Enzyme-Linked Immunosorbent Assay Bordetella pertussis [web.archive.org]
The previous statements that B. pertussis was a nonmotile organism were consistent with a stop codon located in the flagellar biosynthesis gene, flhA, discovered when the B. pertussis Tohama I genome was sequenced and analyzed by Parkhill et al. in 2003 [ncbi.nlm.nih.gov]
- Cough
Consider pertussis in patients with cough longer than 14 days. [web.archive.org]
To search the entire book, enter a term or phrase in the form below Custom Search Bordetella pertussis and Whooping Cough (page 1) (This chapter has 3 pages) © Kenneth Todar, PhD Bordetella pertussis, the agent of pertussis or whooping cough. [textbookofbacteriology.net]
A prolonged cough may be irritating and sometimes a disabling cough may go undiagnosed in adults for many months. [en.wikipedia.org]
CONCLUSIONS: B. pertussis is responsible for an important proportion of whooping cough in hospitalized children in Cajamarca. [ncbi.nlm.nih.gov]
- Paroxysmal Cough
After 7-10 day incubation, a prolonged course ensues,consisting of 3 overlapping stages Catarrhal Paroxysmal coughing Convalescent Partially immune persons and infants older than 6 months may not show all typical features Paroxysmal coughing may be absent [web.archive.org]
Since paroxysmal cough is considered one of the main symptoms of pertussis, we retrospectively assessed the frequency of paroxysmal cough in ARI. Paroxysmal cough was reported by the parents or observed by the clinician. [bmcinfectdis.biomedcentral.com]
Of 564 subjects whose samples were tested by both culture and PCR, 198 (35.1%) had had paroxysmal cough for 7 days or less, and 366 (64.9%) had had paroxysmal cough for more than 7 days at the time of sampling. [jamanetwork.com]
- Common Cold
Initially, symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough. This is then followed by several weeks of severe coughing fits. [osmosis.org]
While common cold and flu viruses can cause ordinary coughs (which can often be relieved with humidifiers and cough syrups), B. pertussis bacteria causes “whooping cough,” a serious cough that can go on for over 6 weeks. [giantmicrobes.com]
The signs and symptoms are similar to a common cold: runny nose, sneezing, mild cough, and low-grade fever. [diagenodediagnostics.com]
Signs and Symptoms When symptoms first start, pertussis tends to look a lot like a common cold, causing a runny nose and perhaps a slight fever and mild cough. The severe coughing spells begin a week or so later. [intermountainhealthcare.org]
- Persistent Cough
Besides the clinical diagnostics (long persisting cough with staccato cough attacks) the serological diagnostics is applied to determine the status of immunity (possibly after vaccination) and an acute infection. [mikrogen.de]
Pertussis, also known as whooping cough, is a respiratory infection that causes a persistent cough in all age groups from the newborn to the elderly. [ibl-international.com]
Gastrointestinal
- Choking
$69.95 $21.90 $19.95 $79.00 $69.00 $69.00 $29.95 $15.95 $18.95 $11.95 Special offers and product promotions WARNING: CHOKING HAZARD -- Small parts. Not for children under 3 yrs. [amazon.com]
The child chokes, gasps and flails the extremities, with eyes bulging and watering and face reddened. There is frequently post-cough vomiting. The paroxysms may be severe enough to bring on cyanosis. This is called the paroxysmal stage. [patient.info]
[…] include symptoms such as: Frequent severe bouts of coughing sometimes followed by vomiting Several rapid coughs followed by a whooping sound as the person inhales; affected adults may cough but not whoop, and infants may have trouble breathing and may choke [labtestsonline.org.au]
You may have choking spells or may cough so hard that you vomit.DR.T.V.RAO MD 4 5. [slideshare.net]
Pertussis infection in infants may cause severe cough, choking, poor feeding, and apnea without paroxysmal cough Footnote 3, Footnote 7, Footnote 10. [canada.ca]
- Gagging
They often have trouble breathing and coughing is frequently followed by vomiting or gagging. The name whooping cough comes from the noise of the cough that ends with a ‘whoop’ sound when the air is drawn back into the chest. [childrens.health.qld.gov.au]
Musculoskeletal
- Arthritis
Pneumonia Legionella pneumophila (Legionellosis)- Pontiac Fever and Legionnaires’ Disease Septic Arthritis ... Streptococcus pneumoniae bacteria cause a wide variety of infections, including pneumonia, bacteremia, otitis media (OM), ... [arupconsult.com]
Urogenital
- Hematuria
Diagnostic work-up of unexplained hematuria and proteinuria during the illness revealed low serum complement component 3 (C3) levels. During follow-up, C3 levels remained low (400-600 mg/L). [ncbi.nlm.nih.gov]
Neurologic
- Febrile Seizures
Moderate or severe systemic reactions (such as fever [105°F or higher], febrile seizures, persistent crying lasting 3 hours or longer, and hypotonic-hyporesponsive episodes) have been reported after administration of DTaP but occur less frequently than [cdc.gov]
Workup
However, whereas a genetic workup for complement regulator mutations was performed, no mutation was found in our patient. [ncbi.nlm.nih.gov]
Tamra Carlson - 2019-06-10 09:52 Disease Topic Infectious Encephalitis workup CSF analysis – critical for diagnosis unless contraindicated (Zunt, Infectious Diseases Society of ... [arupconsult.com]
X-Ray
- Atelectasis
Autopsy studies of pertussis victims performed in the early 20th century revealed a diffuse bronchopneumonia with increased secretion of mucus, associated with airway plugging and atelectasis ( 1 ). [pnas.org]
Serum
- Hyponatremia
Edema and mild hyponatremia were notable predominant symptoms of Bordetella pertussis infection. By exclusion of all other causes, the edema was probably due to inflammation and damage to the capillary wall caused by pertussis toxins. [ncbi.nlm.nih.gov]
Microbiology
- Borrelia Burgdorferi
Tamra Carlson - 2019-06-10 09:28 Disease Topic Borrelia Species- Lyme Disease and Borrelia hermsii Stain/Culture/Identification Recommended Use Identify bacteria in CSF Borrelia burgdorferi (Lyme Disease ) Reflexive Panel ... anaplasmosis, and babesiosis [arupconsult.com]
Treatment
Treatment reduces contagious phase in 5 days and may negate PCR results. B. parapertussis is a related species that may also cause pertussis syndrome; illness usually milder. [web.archive.org]
Here, we describe the disease course, diagnostic difficulties and treatment procedure. After 20 days of treatment based on the doctors’ experience (without an established diagnosis), the child was deemed healthy and discharged. [ncbi.nlm.nih.gov]
Prognosis
[…] vaccine against diphtheria, tetanus, and pertussis acellular pertussis vaccine 5 doses before school-age, completed by 4-6 years of age Tdap vaccine booster vaccine at 11-12 years of age should also be given to pregnant mothers and those around them Prognosis [medbullets.com]
Prognosis : Pertussis usually causes prolonged symptoms: often one to two weeks of cold-like symptoms, followed by several weeks to months of severe coughing. It may take a few more weeks of recovery with gradual clearing of symptoms. [thevaccinemom.com]
Prognosis [ 5 ] The most severe infections are usually in infants, with morbidity and mortality greatest in those aged less than 6 months. [patient.info]
Etiology
M. pneumoniae etiology was diagnosed by culture and RT-PCR. The evolution was fatal for all of the subjects. [ncbi.nlm.nih.gov]
Bordetella pertussis is the etiological agent of whooping cough, a severe infection of the respiratory tract which is particularly dangerous for young infants. [biozentrum.uni-wuerzburg.de]
It is the etiologic agent of whooping cough. [uniprot.org]
Epidemiology
Microbiology Department, University Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, 08950, Spain. 3 CIBER of Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, 28029, Spain. 4 CIBER of Epidemiology and Public [ncbi.nlm.nih.gov]
Defining pertussis epidemiology: clinical, microbiologic and serologic perspectives. Pediatr Infect Dis J. 2005 ; 24 ( 5 Suppl ): S25-S34. (Link to PubMed) Forsyth,K., Tan,T., von Konig,C.H., Caro,J.J., Plotkin,S. [web.archive.org]
Pathophysiology
One of the important considerations in the design of a new vaccine is the pathophysiology of pertussis; identification of individual virulence factors and assessment of their roles in the disease will provide a sound basis for vaccine development, which [creative-diagnostics.com]
It causes inflammation and necrosis of the respiratory tract ciliated epithelium and it produces immunological and pathophysiological reactions. [diesse.it]
Useful For Suggests clinical disorders or settings where the test may be helpful Diagnosis of recent infection with Bordetella pertussis in patients with > or =2 weeks of symptoms consistent with whooping cough Clinical Information Discusses physiology, pathophysiology [mayomedicallaboratories.com]
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Bordetella pertussis, the causative agent of whooping cough, is highly contagious and remains endemic in the United States despite [mayocliniclabs.com]
Prevention
Acellular pertussis vaccination in baboons induces a Th2-skewed immune response and prevents pertussis-associated symptoms but does not prevent mucosal colonization or host-to-host transmission. [doi.org]
(August 31, 2015) Centers for Disease Control and Prevention. Pertussis. Available online at http://www.cdc.gov/pertussis/. Accessed October 2015. (August 31, 2015) Centers for Disease Control and Prevention. Pertussis, Diagnosis Confirmation. [labtestsonline.org]
Centers for Disease Control and Prevention (2015). "Pertussis". In Atkinson, W.; Wolfe, S.; Hamborsky, J. (eds.). Epidemiology and Prevention of Vaccine-Preventable Diseases: The Pink Book (13th ed.). Public Health Foundation. [en.wikipedia.org]
Prevention Pertussis is a vaccine-preventable infection. There are four combination vaccines used to prevent diphtheria, tetanus and pertussis: DTaP, Tdap, DT, and Td. [dentalcare.com]