A discussion of the history of the use of boric acid by the medical profession follows the patient presentation. [ncbi.nlm.nih.gov]

• Fever

  Although in the general ward the patient's fever persisted and nausea, vomiting and headache often recurred, possibly because of an insufficient dose of furosemide, the patient's condition steadily improved over the 64 h after admission. [ncbi.nlm.nih.gov]

  Aspirin also reduces fever. Rectal aspirin is used to reduce pain, inflammation, and fever. Aspirin is also used to treat the symptoms of arthritis and rheumatic fever. doxycycline (Vibramycin) Doxycycline is a tetracycline antibiotic. [emedicinehealth.com]

  Symptoms of boric acid poisoning include bluish green vomit, a bright red rash on the skin, blisters, drowsiness, fever and diarrhea. [livestrong.com]

• Weight Loss

  […] and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - changes in calcium Nutritional and Gross Metabolic - changes in phosphorus TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES [chemsrc.com]

  After the pressure-impregnation of a water borne solution containing 9.78 mol/L of boron, the fire properties were evaluated by cone calorimeter (CCM) and weight loss (WL). [dx.doi.org]

  Rabbits given boric acid at 800 mg/kg body weight per day for 4 days showed anorexia, weight loss, and diarrhoea; 850 and 1000 mg/kg body weight per day for 4 days caused 100% mortality (Draize & Kelley, 1959). [inchem.org]

• Fatigue

  Among all patients, the only symptoms remaining 72 hours after the meal were mild headache, fatigue, and peeling skin. [ncbi.nlm.nih.gov]

  The woman lost almost all of her body and scalp hair; other clinical signs included erythema on the palms of her hands, severe fatigue, anorexia, and mental confusion. [inchem.org]

• Gastric Lavage

  She was immediately treated with gastric lavage and intravenous sodium bicarbonate fructose. The woman developed contractions, and an emergency caesarean delivery was scheduled. [inchem.org]

• Pathologist

  It is known among forensic and pediatric pathologists that the demonstration of pancreatic inclusions is considered to have diagnostic significance in cases of boric acid poisoning. [ncbi.nlm.nih.gov]

• Vomiting

  On admission, he had vomiting, diarrhea, and hiccups. Laboratory data was diagnostic of acute renal failure. Hemodialysis and charcoal hemoperfusion were performed in series. [doi.org]

  TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Behavioral - fluid intake Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting [chemsrc.com]

• Nausea

  […] or vomiting TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Behavioral - fluid intake Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea [chemsrc.com]

  Vomiting, nausea, diarrhea, and abdominal cramps were rather common. Systemic effects were notably absent in acute ingestions. Five of three hundred sixty-four patients had measured serum levels and were the only ones hospitalized. [ncbi.nlm.nih.gov]

• Diarrhea

  On admission, he had vomiting, diarrhea, and hiccups. Laboratory data was diagnostic of acute renal failure. Hemodialysis and charcoal hemoperfusion were performed in series. [doi.org]

  Gastrointestinal - nausea or vomiting TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Behavioral - fluid intake Gastrointestinal - hypermotility, diarrhea [chemsrc.com]

• Hematemesis

  Gastrointestinal toxicity include persistent nausea, vomiting, diarrhea, epigastric pain, hematemesis, and blue-green discoloration of the feces and vomit 4. [drugbank.ca]

• Epigastric Pain

  Gastrointestinal toxicity include persistent nausea, vomiting, diarrhea, epigastric pain, hematemesis, and blue-green discoloration of the feces and vomit 4. [drugbank.ca]

• Cyanosis

  hypermotility, diarrhea TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1780 mg/kg TOXIC EFFECTS : Brain and Coverings - meningeal changes Lungs, Thorax, or Respiration - cyanosis [chemsrc.com]

  In severe cases, shock with fall in arterial pressure, tachycardia (increase in heart rate) and cyanosis (blue skin colour) may occur. [web.archive.org]

  Toxic signs in dogs given boric acid (0.2-2.0 g/kg body weight) orally in combination with subcutaneous morphine to prevent vomiting were cyanosis of mucous membranes, red-violet skin colour, rigidity of legs, convulsion, and shock-like syndrome (Pfeiffer [inchem.org]

• Hypotension

  Two days later, he presented to the hospital with hypotension, metabolic acidosis, oliguric renal failure, a generalized erythematous rash, and several superficial skin abrasions. [ncbi.nlm.nih.gov]

• Muscle Cramp

  Other symptoms (primarily CNS and cutaneous) occurred in six or fewer cases: lethargy, rash, headache, light-headedness, fever, irritability, and muscle cramps. The average dose ingested estimated from 659 cases was 1.4 g (range 0.010-88.8 g). [inchem.org]

• Alopecia

  He subsequently developed erythema of both palms as well as alopecia totalis. [ncbi.nlm.nih.gov]

  Chronic intoxication with boric acid may give rise to anorexia, loss of strength, confusion and loss of hair (alopecia). Reproductive effects, such as low sperm count, were seen in men exposed to boron over the long-term. [web.archive.org]

  Stein KM, Odom RB, Justice GR, & Martin GC (1973) Toxic alopecia from ingestion of boric acid. Arch Dermatol, 108: 95-97. Stelter LH (1980) Baseline levels of selected trace elements in Colorado oil shale region animals. J Wildl Dis, 16: 175-182. [inchem.org]

• Flushing

  Launder contaminated clothing before reuse.If in eyes: Flush with large amounts of water, lifting upper and lower lids occasionally. [ebay.com]

  Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. [cameochemicals.noaa.gov]

  WITH electrolytes, or you'll flush electrolytes right out of your system and cause much worse issues than you can possibly imagine. How do you know if you are drinking just enough fluids? If your urine has a super light yellow tint to it. [earthclinic.com]

• Chronic Dermatitis

  Acquired stenosis of the external auditory canal (EAC) may occur because of chronic external otitis, recurrent chronic catarrhal otitis media associated with tympanic membrane perforation, chronic dermatitis, tumors, and trauma. [ncbi.nlm.nih.gov]

• Facial Redness

  Doxycycline will not treat facial redness caused by rosacea. [emedicinehealth.com]

• Oliguria

  However, boric acid has potentially fatal actions such as hypotension, metabolic acidosis and oliguria. Death may result from circulation collapse and shock. [ncbi.nlm.nih.gov]

  The kidneys (producing oliguria (small volume of urine), albuminuria (presence of albumin in the urine), anuria (absence of or defective excretion of urine)) and, rarely, the liver (jaundice) may also be involved. [web.archive.org]

• Seizure

  We report 7 infants suffering from seizures induced by chronic boric acid ingestion. The boric acid was given by dipping a soother in a proprietary borax and honey mixture. The babies have remained well since the mixture was withheld. [ncbi.nlm.nih.gov]

  […] reported other than lethal dose value TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Human - infant DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure [chemsrc.com]

  As the condition worsens, a person may develop a fever, blisters on the skin, seizures, a coma, decreased blood pressure, sloughing of the skin and a coma. It is important to keep boric acid well labeled and out of the reach of children. [livestrong.com]

  Google Scholar Gordon A S, Prichard J S and Freedman MH 1973 Seizure disorders and anaemia associated with chronic borax intoxication. Can. Med. Assoc J. 108, 719-721. Google Scholar Gordon V (Ed) 1987 The case of the toxic life-preserver. [doi.org]

• Excitement

  Then the carrom pucks move much faster, making the game very exciting! But there is a lot more to boric acid. In many industries, it is mixed with vegetable oils to make a very effective lubricant. [web.archive.org]

• Dizziness

  Meclizine is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. [emedicinehealth.com]

• Aspergillus Niger

  Aspergillus niger infection of an exenterated orbit is a very rare occurrence. Treatment includes extensive surgical debridement with socket lavage with 0.6% hydrogen peroxide, oral itraconazole, and local amphotericin B. [ncbi.nlm.nih.gov]

  Bowen & Gauch (1966) exposed the fungi Saccharomyces cerevisiae, Neurospora crassa, Aspergillus niger, and Penicillium chrysogenum to boron. [inchem.org]

Self-administration of treatment intravaginally for 10 days will be followed by clinical assessment at 7 and 30 days (days 17 and 40, respectively) after the end of the treatment phase. [ncbi.nlm.nih.gov]

This report emphasizes the need to recognize agents that contain boric acid as an etiology of unexplained delirium and profound shock. [ncbi.nlm.nih.gov]

However, boron mediated reprotoxic effects have not been proven in epidemiological studies so far. [ncbi.nlm.nih.gov]

Recent epidemiologic studies indicate that non- albicans Candida spp. are more resistant to conventional antifungal treatment with azoles and are considered as causative pathogens of vulvovaginal candidiasis. [doi.org]

Luoto, National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland Dr F.H. [inchem.org]

OBJECTIVE: Our purpose was to examine the efficacy of a topical long-term treatment with boric acid versus an oral long-term treatment (itraconazole) in the cure and prevention of recurrent vulvovaginal candidiasis. [ncbi.nlm.nih.gov]

Alendronate slows bone loss while increasing bone mass, which may prevent bone fractures. Alendronate is used to treat or prevent postmenopausal osteoporosis and steroid-induced osteoporosis. [emedicinehealth.com]