Presentation
Complications and side effects of the therapy are presented as well. The final chapter is reserved for other dermatological indications like anal fissure and wrinkles. [books.google.de]
Presented at the Vlth International Orthoptic Congress, Harrogate, 1987. 11 Magoon E : Botulinum toxin chemo-denervation in infants and children. J Ped Ophthalmol and Strab 1986, 21 : 110–12. [nature.com]
She was also diagnosed with ocular MG seven years prior to presentation causing a variable ptosis and diplopia. [omicsonline.org]
The table below presents the most frequently reported adverse reactions within 12 weeks of injection. [rxlist.com]
Entire Body System
- Cerebral Palsy
Diagnosed with Cerebral Palsy at birth, Adam’s condition caused stiffness in his right arm and wrist. And, the latest research reports positive results over a two-year period for patients with Cerebral Palsy. Dr. [cerebralpalsy.org]
Drooling in cerebral palsy and Parkinson’s disease In children with cerebral palsy and in adults with Parkinson’s disease, there is often excessive drooling, and this can be helped by injecting botulinum toxin into the salivary glands beneath the jaw [myvmc.com]
Successful treatment of childhood spasticity secondary to cerebral palsy using Botox. Tenn Med. 2003; 96(11):511-3. Ramirez-Castaneda J, Jankovic J. [paindoctor.com]
Researchers in New Zealand were testing Botox as means to help improve movement in children with a form of cerebral palsy called hemiplegia in 2004. [medical-dictionary.thefreedictionary.com]
Botulinum toxin treatment was originally introduced to treat muscle spasms, including blepharospasm (spasms of the eyelids), strabismus (squint), cervical dystonia (torticollis of the neck) and spasticity due to cerebral palsy or other muscular diseases [dermnetnz.org]
- Fever
When this medication is used for overactive bladder, side effects such as urinary tract infections, burning/ painful urination, fever, or difficulty urinating may occur. [webmd.com]
Other events reported in 2-10% of patients in any one study in decreasing order of incidence include: increased cough, flu syndrome, back pain, rhinitis, dizziness, hypertonia, soreness at injection site, asthenia, oral dryness, speech disorder, fever [rxlist.com]
[…] drooping eyelids; any other abnormal facial change; have symptoms of a urinary tract infection (UTI) and are being treated for urinary incontinence (symptoms of a urinary tract infection may include pain or burning with urination, frequent urination, or fever [botox.com]
[…] frequently reported adverse events (3%-10% of adult patients) following injection of BOTOX ® for severe primary axillary hyperhidrosis include injection-site pain and hemorrhage, nonaxillary sweating, infection, pharyngitis, flu syndrome, headache, fever [botoxmedical.com]
Respiratoric
- Hoarseness
The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, [botoxblepharospasm.com]
Other possible side effects include: Blurred vision Double vision Drooping eyelids Difficulty swallowing Fatigue Hoarseness or loss of voice Loss of bladder control Loss of strength Muscle weakness Nausea Respiratory problems Trouble speaking clearly [cerebralpalsy.org]
- Aspiration
Serious Adverse Reactions With Unapproved Use Serious adverse reactions, including excessive weakness, dysphagia, and aspiration pneumonia, with some adverse reactions associated with fatal outcomes, have been reported in patients who received BOTOX ® [botoxmedical.com]
Skin
- Sweating
In the first part the pathophysiology of hyperhidrosis, rare forms of sweating and their symptoms, as well as the different topical and surgical treatments for focal hyperhidrosis are discussed. The second part deals with botulinum toxin. [books.google.de]
This way the function of the sweat glands is eased, and one treatment enables a period of at least 6 months to a year with no increased sweating. [en.dermatim.net]
When used to treat excessive sweating in the armpits, Botox is injected directed into the axillary skin. Localised discomfort and bruises can occur, but no sedation or local anaesthesia is generally required. [patient.info]
The treatment works against sweating by blocking the signals sent by nerves to the sweat glands. Botox takes three to four hours to bind to acetylcholine receptors, Newman said. [livescience.com]
- Hyperhidrosis
In the first part the pathophysiology of hyperhidrosis, rare forms of sweating and their symptoms, as well as the different topical and surgical treatments for focal hyperhidrosis are discussed. The second part deals with botulinum toxin. [books.google.de]
Beyond its use to combat facial imperfections, Botox is deployed to treat ailments such as cervical dystonia, hyperhidrosis or excessive sweating, lazy eye and overactive bladders. [naturalfacedr.com]
Hyperhidrosis Hyperhidrosis means there is an excessive production of sweat from the glands in the skin, which can be very troublesome for some. [myvmc.com]
When Botox is used to treat hyperhidrosis (excessive sweating), injections are inserted into the skin of the armpits. [medic8.com]
BOTOX® is approved for treatment of frown lines on the forehead, crow’s feet (lines around the eye), and axillary hyperhidrosis (increased sweating of the armpits). [my.clevelandclinic.org]
- Increased Sweating
This way the function of the sweat glands is eased, and one treatment enables a period of at least 6 months to a year with no increased sweating. [en.dermatim.net]
BOTOX® is approved for treatment of frown lines on the forehead, crow’s feet (lines around the eye), and axillary hyperhidrosis (increased sweating of the armpits). [my.clevelandclinic.org]
Eyes
- Blurred Vision
Diplopia (Blurred Vision) In some cases of Diplopia (double vision), the use of Botox ® is an effective treatment. This condition can be present in one eye or both. [brandoneye.com]
Learn how the medication known as Botox may reduce eyelid spasms, help crossed eyes, and treat other eye problems such as blurred vision (diplopia). [everydayhealth.com]
The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, [botoxblepharospasm.com]
It can be source of blurred vision. 4- Exposure keratitis – Exposure keratitis is due to difficulty to close completely the eye (lagophtalmos). [infodystonia.com]
Contraindications Pregnancy Nursing Some neuromuscular diseases Possible adverse effects Temporarily weak or heavy feeling eyelid Droopy eyelid (ptosis) Blurred vision Double vision (diplopia) Inability to close the eye (lagophthalmos) Sagging mouth Brow [bellspalsy.ws]
- Swelling of Eyelid
Other side effects of BOTOX ® and BOTOX ® Cosmetic include: dry mouth, discomfort or pain at injection site, tiredness, headache, neck pain, eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of eyelids, dry eyes [botox.com]
Urogenital
- Incontinence
In people being treated for urinary incontinence other side effects include: urinary tract infection, painful urination, and/or inability to empty your bladder on your own. [botox.com]
This can cause serious problems such as trouble speaking, breathing, or swallowing, impaired vision, bladder incontinence, and muscle weakness. Complications such as these should be immediately reported to a doctor. [paindoctor.com]
Botulinum toxin type A can also be injected into the bladder muscle to help treat certain cases of incontinence due to overactive bladder. [mydr.com.au]
Botox was first approved by the FDA to treat blepharospasm and strabimus, Botox and its competitive manufacturers were given the thumbs up to treat adults with spasticity in the flexor muscles of the elbow, wrist, and fingers, migraines and urinary incontinence [cerebralpalsy.org]
Table 14 presents the most frequently reported adverse reactions in a placebo-controlled, double-blind post-approval 52 week study with BOTOX 100 Units (Study NDO-3) conducted in MS patients with urinary incontinence due to detrusor overactivity associated [rxlist.com]
- Hematuria
First 12 Weeks after Intradetrusor Injection in Double-blind, Placebo-controlled Clinical Trials (NDO-1 and NDO-2) Adverse Reactions BOTOX 200 Units (N=262) Placebo (N=272) Urinary tract infection 64 (24%) 47 (17%) Urinary retention 45 (17%) 8 (3%) Hematuria [rxlist.com]
[…] frequently reported adverse reactions within 12 weeks of BOTOX ® injection for detrusor overactivity associated with a neurologic condition include urinary tract infection (BOTOX ® 24%, placebo 17%), urinary retention (BOTOX ® 17%, placebo 3%), and hematuria [botoxmedical.com]
Neurologic
- Paresthesia
Paresthesia or dysesthesia in the treatment area is rare, and may be caused by nerve trauma. Anxiety with injection procedures is common. [aafp.org]
These reactions include: abdominal pain; alopecia, including madarosis; anorexia ; brachial plexopathy; denervation /muscle atrophy ; diarrhea; hyperhidrosis; hypoacusis; hypoaesthesia; malaise ; paresthesia ; peripheral neuropathy ; radiculopathy ; erythema [rxlist.com]
- Clonus
The spasticity is shown by an increase in muscle stretch reflexes (for example, knee jerk with tapping of the tendon) and clonus (rhythmic, repetitive movement of a joint when its muscle is stretched and held all of a sudden). [cincinnatichildrens.org]
- Somnolence
All of these medications can be associated with muscle weakness, somnolence (sleepiness), dizziness, imbalance, and fogginess. [pacificneuroscienceinstitute.org]
- Tingling
Possible side effects that may be experienced after the injection include: Burning sensations Swelling Bleeding and bruising at the injection site Tingling in the arms or legs A flu-like illness Blurred vision If the Botox injections are for headaches [paindoctor.com]
Treatment
Oliver Philip Kreyden, Roland Böni, Günter Burg Karger Medical and Scientific Publishers, 2002 - 254 Seiten In this publication a comprehensive overview on the pathophysiology and treatment of hyperhidrosis with a focus on the new therapy with botulinum [books.google.de]
BOTOX® and Blepharospasm (Eye Spasm) Treatment BOTOX® is also administered for strabismus (crossed eyes) and blepharospasm treatment. [docshop.com]
Most effects of the BOTOX® treatment are noticed in 3-5 days. You may return to your normal routine immediately after treatment. There is a small lump immediately after treatment which usually goes away within the first hour. [centralfloridaeye.com]
The average cost of a botulinum toxin treatment such as Botox Cosmetic was $376 in 2016. Costs may vary depending on the number of injections, the size of the treatment area, and the geographic location where you receive treatment. [healthline.com]
Prognosis
It is not intended to provide instruction and you should not rely on this information to determine diagnosis, prognosis or a course of treatment. It should not be used in place of a professional consultation with a doctor. [dystonia.org.uk]
Etiology
The Anatomy of the Greater Occipital Nerve: Implications on the Etiology of Migraine Headaches. Plast. Recon. Surg 113(2):693-7. Copyright © 2006 by Dr. Scott W. Mosser. [drmosser.com]
Spasticity: Etiology, evaluation, management, and the role of botulinum toxin type A. Muscle Nerve Suppl. 1997; 20(S6): 1-231. [ Abstract ] Specific references Allergan Australia. Product Information: Botox. [myvmc.com]
Pathophysiology
Oliver Philip Kreyden, Roland Böni, Günter Burg Karger Medical and Scientific Publishers, 2002 - 254 Seiten In this publication a comprehensive overview on the pathophysiology and treatment of hyperhidrosis with a focus on the new therapy with botulinum [books.google.de]
Prevention
Botox smooths these wrinkles by preventing facial muscle contraction. If people start treatment early enough, they can even prevent permanent wrinkling from taking place, he added. [livescience.com]
Botox is injected into the muscles to prevent abnormal muscle function and spasms in people who have conditions that cause excessive nerve stimulation. [medic8.com]
This preventative process has been established in an identical twin study. One twin received Botox starting in her mid-thirties while the other did not. [wweyecenter.com]
Can Botox injections be used to prevent wrinkles developing? There is increasing interest among younger people in the possibility of using Botox injections to prevent wrinkles. [mydr.com.au]