There were similar smaller papules present on the adjacent area and over the prepuce. Blood VDRL and HIV screening test were nonreactive. [ncbi.nlm.nih.gov]

We described an adult male presenting with well defined, purplish papules of varying size with verrucous to smooth surface distributed discretely over medial side of the left thigh, scrotum, and penile shaft. [cdriadvlkn.org]

• Fishing

  These finding coincided with disappearance of the virus in the lesion, as revealed by PCR and FISH analysis. [clincancerres.aacrjournals.org]

  (In one case, treatment of BP with imiquimod 5% cream 3-times weekly for 4 months resulted in clinical resolution of BP as well as disappearance of lesion by PCR and FISH analysis. The virus in this case was in the episomal form. [dermatologyadvisor.com]

• Foul Smelling Discharge

  Per speculum examination of spouse showed thick, white, foul smelling discharge with hypertrophied cervix. Pap smear More Details from spouse showed inflammatory infiltrate with moderate-to-severe dysplasia. [cdriadvlkn.org]

• Dentist

  A 35-year-old dentist came to the authors' attention for papular and vegetating lesions that had appeared on his penile shaft over the last 2 months. [ncbi.nlm.nih.gov]

• Lymphedema

  Wood, Transformation of the common wart into squamous cell carcinoma in a patient with primary lymphedema, Cancer, 48, 3, (820-824), (2006). Thomas R. Wade and A. [doi.org]

• Papule

  Multiple linear bowenoid papulosis without surrounding papules. J Dermatol 2012; 39: 862-3. Kopf AW, Bart RS. Tumor conference No. 11: multiple bowenoid papules of the penis: a new entity? J Dermatol Surg Oncol 1977; 3: 265-9. [termedia.pl]

  However, dermatologists still recognize a distinct clinical variant, bowenoid papulosis, characterized by discrete papules in a younger age group and a tendency for spontaneous regression. [en.wikipedia.org]

  Clinical variants of BP such as papules coalescing to form plaques, lichenoid papules, macules, and leukoplakia-like lesions have been described. [1] In the present case, both genital and adjacent extragenital sites were involved. [cdriadvlkn.org]

  Skin biopsies were taken from the asymptomatic papule and from the edge of the ulcerated scrotal lesion. The papule showed near absence of maturation and moderate atypia of the squamous cells. Mitotic figures were seen above the basal layer. [ijdvl.com]

  It occurs on the genitalia of both sexes in sexually active young people as well-demarcated pigmented warty papules. Affects all races equally. The condition was originally described in 1977 by Kopf and Bart as papules on the penis. Bibliography A. [whonamedit.com]

• Angiokeratoma

  Lichen nitidus Molluscum contagiosum Fordyce spots Lichen simplex chronicus Squamous cell carcinoma Melanoma Basal cell carcinoma Scabies Angiokeratoma / angiokeratoma of scrotum Syringomas Condyloma lata Granular cell tumor Papular acantholytic dermatosis [visualdx.com]

• Genital Lesions

  The human papillomavirus causes a variety of genital lesions: condyloma acuminatum, bowenoid papulosis (carcinoma in situ), and squamous cell carcinoma. Only condylomata have been documented to be sexually transmitted. [ncbi.nlm.nih.gov]

  Discussion Bowenoid papulosis is clinically a benign appearing genital lesion showing histologic features of squamous cell carcinoma-in-situ. [ijdvl.com]

  These include common warts, flat pityriasis versicolor suh as lesions in epidermodysplasia verruciformis, oral and laryngeal papillomas, and various genital lesions. [4] Immune response appears to play a role in the development of BP. [cdriadvlkn.org]

  Alberto Rosenblatt, Homero Gustavo de Campos Guidi and Walter Belda, Premalignant Lesions of the Penis, Male Genital Lesions, 10.1007/978-3-642-29017-6_16, (375-401), (2012). A. Wikström, M.‐A. Hedblad and S. [doi.org]

• Penile Lesion

  lesions Typical appearance in female Gross description Multiple small pigmented papular lesions, may resemble condyloma acuminatum Microscopic (histologic) description Resembles basaloid PeIN but may have mild / heavy melanin pigmentation within the [pathologyoutlines.com]

• Lymphocytic Infiltrate

  Within the dermis, there was a mild, superficial perivascular lymphocytic infiltrate with a few melanophages (Figure 2). On the basis of the clinical and histological features, the diagnosis of linear Bowenoid papulosis (LBP) was established. [termedia.pl]

Case one - Lesion on the scrotum (a) before treatment and (b) after two weeks of treatment Case one - histopathology showing acanthosis and dyskeratosis H and E, ×10 Case one - histopathology showing epidermal dysmaturation and dyskeratosis, H and E, [ncbi.nlm.nih.gov]

The treatment for BP is conservative as it usually regresses spontaneously. [jddonline.com]

Imiquimod has proven effective in combating viral infections as well as UV-induced (pre) malignant lesions, and seems also effective in the treatment of BP.Because so far imiquimod treatment has not been related to the physical status of HPV, we present [clincancerres.aacrjournals.org]

(Topical treatment of BP of the penis with imiquimod 5% cream every other day for 8 weeks resulted in no recurrences 3 months after cessation of treatment.) Nakanishi, G, Yamasaki, O, Nagao, Y, Tanaka, T. [dermatologyadvisor.com]

Treatment - Bowenoid papulosis Because Bowenoid papulosis usually runs a benign course with many cases spontaneously regressing, treatment is often unnecessary. [checkorphan.org]

Bowenoid papulosis may be a chronic dysplasia with a variable long-term prognosis linked to a cocarcinogenic factor. [ncbi.nlm.nih.gov]

Bowenoid papulosis may be a chronic dysplasia with a variable long-term prognosis linked to a cocarcinogenic factor. ( Arch Dermatol 1984;120:514-516) [jamanetwork.com]

It has poor prognosis due to invasion depth and increased risk of metastasis. We present the case of a 56-year-old man who developed an invasive penile squamous-cell carcinoma after a six-year history of Bowenoid papulosis. [rojced.com]

Prognosis - Bowenoid papulosis The condition usually resolves itself with time but they should be regularly checked due to the risk of malignancy. [checkorphan.org]

Diagnostic Technologies and Molecular and Cellular Profiling: Determinants of Patient Prognosis, Ernst-Jan M. [clincancerres.aacrjournals.org]

The distinction between the two lesions is of importance as Bowen's disease represents a precancerous dermatosis and bowenoid papulosis a probably benign lesion of viral etiology. [unboundmedicine.com]

[…] penile intraepithelial neoplasia (males) or vulvar intraepithelial neoplasia (females) Epidemiology Preferentially affects sexually active young males (mean age 30 years) Sites Primarily penile shaft; may also be present in foreskin, glans or scrotum Etiology [pathologyoutlines.com]

Evidence supports an etiologic role of human papillomavirus (HPV), particularly type 16. HPV-16 is also associated with an increased risk for cervical intraepithelial neoplasia (CIN) and invasive carcinoma. [ncbi.nlm.nih.gov]

[…] bowenoid papulosis progressing to Bowen's disease. [3] According to Wade there is a potential for bowenoid papulosis to become invasive squamous cell carcinoma and he advises complete removal of the lesion. [3] From the earlier description onwards the etiology [ijdvl.com]

Recommend to your librarian Human papilloma virus (HPV) is known to be an etiologic agent for benign warts of the skin. [f1000.com]

The discovery of a possible oncogenic virus in BP and the epidemiologic behavior of carcinoma in situ and multicentric carcinomas suggest the need for a very careful follow-up evaluation of such lesions. [ncbi.nlm.nih.gov]

Terminology Type of penile intraepithelial neoplasia (males) or vulvar intraepithelial neoplasia (females) Epidemiology Preferentially affects sexually active young males (mean age 30 years) Sites Primarily penile shaft; may also be present in foreskin [pathologyoutlines.com]

Epidemiology Frequency Bowenoid papulosis lesions are related clinically to genital warts. They share the same age of onset in patients and are transmitted sexually. [emedicine.com]

Pathophysiology Bowenoid papulosis is an asymptomatic focal epidermal hyperplasia and dysplasia induced by HPV infection [1, 2] (most commonly by HPV 16). [emedicine.com]

Prevention - Bowenoid papulosis Not supplied. Diagnosis - Bowenoid papulosis Not supplied. Prognosis - Bowenoid papulosis The condition usually resolves itself with time but they should be regularly checked due to the risk of malignancy. [checkorphan.org]

Luckily there exists a vaccine – Gardasil – that both young boys and girls may receive which prevents infection from certain HPV strains that are most likely to lead to cancer. [contourderm.com]

New HPV vaccines have been approved and recommended by the CDC to help prevent cervical cancer in women. [aocd.org]

ABSTRACT: Copy: The injectable adipocytolytic drug deoxycholic acid (DCA) is the f... more The Role of Topical Retinoids in Prevention and Treatment of Atrophic Acne .... ABSTRACT: Atrophic acne scarring is a frequent occurrence among acne patients. [jddonline.com]

A patient with BP should be thoroughly educated regarding HPV infection and emphasis should be on prevention. [cdriadvlkn.org]