Symptoma

Bowenoid Papulosis

A 23-year-old man with bowenoid papulosis of the penis is presented. The lesions were present for two months prior to diagnosis. All of the lesions resolved without treatment within two months of diagnosis. [ncbi.nlm.nih.gov]

We described an adult male presenting with well defined, purplish papules of varying size with verrucous to smooth surface distributed discretely over medial side of the left thigh, scrotum, and penile shaft. [cdriadvlkn.org]

  • Lymphedema

    Wood, Transformation of the common wart into squamous cell carcinoma in a patient with primary lymphedema, Cancer, 48, 3, (820-824), (2006). Thomas R. Wade and A. [doi.org]

    [Chronic vulvar lymphedema revealing Crohn disease in a teenage girl]. [science.gov]

  • Foul Smelling Discharge

    Per speculum examination of spouse showed thick, white, foul smelling discharge with hypertrophied cervix. Pap smear More Details from spouse showed inflammatory infiltrate with moderate-to-severe dysplasia. [cdriadvlkn.org]

  • Dentist

    A 35-year-old dentist came to the authors' attention for papular and vegetating lesions that had appeared on his penile shaft over the last 2 months. [ncbi.nlm.nih.gov]

  • Inguinal Lesions

    The perianal and left inguinal lesions revealed invasive SCC on histology. HPV-31 and HPV-67 sequences were detected by polymerase chain reaction from BP lesions of the perianal area and the shaft of the penis. [ncbi.nlm.nih.gov]

  • Hypotension

    Clinical findings of peripheral vasodilation, hypotension, bradycardia and asystole observed during the administration of spinal anesthesia were recorded. [science.gov]

  • Papule

    Multiple linear bowenoid papulosis without surrounding papules. J Dermatol 2012; 39: 862-3. Kopf AW, Bart RS. Tumor conference No. 11: multiple bowenoid papules of the penis: a new entity? J Dermatol Surg Oncol 1977; 3: 265-9. [termedia.pl]

    It occurs on the genitalia of both sexes in sexually active young people as well-demarcated pigmented warty papules. Affects all races equally. The condition was originally described in 1977 by Kopf and Bart as papules on the penis. Bibliography A. [whonamedit.com]

    We recently encountered a patient who presented with papules in the anal area. Human papillomavirus has been identified as the causative agent. [ncbi.nlm.nih.gov]

    However, dermatologists still recognize a distinct clinical variant, bowenoid papulosis, characterized by discrete papules in a younger age group and a tendency for spontaneous regression. [en.wikipedia.org]

    Clinical variants of BP such as papules coalescing to form plaques, lichenoid papules, macules, and leukoplakia-like lesions have been described. [1] In the present case, both genital and adjacent extragenital sites were involved. [cdriadvlkn.org]

  • Koebner Phenomenon

    A possible Koebner phenomenon. Int J Dermatol 1990; 29: 430-1. Wade TR, Kopf AW, Ackerman AB. Bowenoid papulosis of the penis. Cancer 1978; 42: 1890-903. Patterson JW, Kao GF, Graham JH, et al. Bowenoid papulosis. [termedia.pl]

  • Genital Lesions

    The human papillomavirus causes a variety of genital lesions: condyloma acuminatum, bowenoid papulosis (carcinoma in situ), and squamous cell carcinoma. Only condylomata have been documented to be sexually transmitted. [ncbi.nlm.nih.gov]

    Discussion Bowenoid papulosis is clinically a benign appearing genital lesion showing histologic features of squamous cell carcinoma-in-situ. [ijdvl.com]

    These include common warts, flat pityriasis versicolor suh as lesions in epidermodysplasia verruciformis, oral and laryngeal papillomas, and various genital lesions. [4] Immune response appears to play a role in the development of BP. [cdriadvlkn.org]

    Alberto Rosenblatt, Homero Gustavo de Campos Guidi and Walter Belda, Premalignant Lesions of the Penis, Male Genital Lesions, 10.1007/978-3-642-29017-6_16, (375-401), (2012). A. Wikström, M.‐A. Hedblad and S. [doi.org]

The histologic workup of the resection specimen revealed patchy high-grade vulvar intraepithelial neoplasia Grade 3 (VIN 3) and 2 microscopic foci of superficially invasive squamous cell carcinoma. [science.gov]

  • Skin Test Positive

    Lesional skin tested positive with the Digene hybrid capture system cocktail assay that identifies infection with a mixture of high to intermediate oncogenic human papillomavirus (HPV) types, including types 16, 18, 31, 33, 35, 45, 51, 52, and 56. [ncbi.nlm.nih.gov]

  • Lymphocytopenia

    As far as we are aware, this is the first documented case of BP (genital or extragenital) associated with idiopathic CD4 lymphocytopenia. [ncbi.nlm.nih.gov]

    Isolated human papillomavirus 18-positive extragenital bowenoid papulosis and idiopathic CD4 lymphocytopenia. Br J Dermatol 2001;144:619-21. [ PUBMED ] 4. Gross G, Ikenberg H, Gissmann L, Hagedorn M. [cdriadvlkn.org]

    Snead, Isolated human papillomavirus 18‐positive extragenital bowenoid papulosis and idiopathic CD4 lymphocytopenia, British Journal of Dermatology, 144, 3, (619-621), (2001). Maria L. Fornatora, Anne Cale Jones, Stanley M. Kerpel and Paul D. [doi.org]

  • Lymphocytic Infiltrate

    Within the dermis, there was a mild, superficial perivascular lymphocytic infiltrate with a few melanophages (Figure 2). On the basis of the clinical and histological features, the diagnosis of linear Bowenoid papulosis (LBP) was established. [termedia.pl]

    Examination of the biopsy specimen revealed a dense CD30 lymphocytic infiltrate; no evidence of systemic malignancy was evident on positron emission tomography. [science.gov]

Imiquimod has proven effective in combating viral infections as well as UV-induced (pre) malignant lesions, and seems also effective in the treatment of BP.Because so far imiquimod treatment has not been related to the physical status of HPV, we present [clincancerres.aacrjournals.org]

The treatment for BP is conservative as it usually regresses spontaneously. [jddonline.com]

Case one - Lesion on the scrotum (a) before treatment and (b) after two weeks of treatment Case one - histopathology showing acanthosis and dyskeratosis H and E, 10 Case one - histopathology showing epidermal dysmaturation and dyskeratosis, H and E, 45 [ncbi.nlm.nih.gov]

Treatment - Bowenoid papulosis Because Bowenoid papulosis usually runs a benign course with many cases spontaneously regressing, treatment is often unnecessary. [checkorphan.org]

Treatments for Bowen's disease There are a number of treatment options for Bowen's disease. Talk to your dermatologist about which treatment is most suitable for you. [beaconmedicalgroup.nhs.uk]

Bowenoid papulosis may be a chronic dysplasia with a variable long-term prognosis linked to a cocarcinogenic factor. [ncbi.nlm.nih.gov]

Bowenoid papulosis may be a chronic dysplasia with a variable long-term prognosis linked to a cocarcinogenic factor. ( Arch Dermatol 1984;120:514-516) [jamanetwork.com]

It has poor prognosis due to invasion depth and increased risk of metastasis. We present the case of a 56-year-old man who developed an invasive penile squamous-cell carcinoma after a six-year history of Bowenoid papulosis. [rojced.com]

Prognosis - Bowenoid papulosis The condition usually resolves itself with time but they should be regularly checked due to the risk of malignancy. [checkorphan.org]

For these reasons the prognosis of someone with bowenoid papulosis is quite good. The elderly, HIV patients, and people who are otherwise immunosuppressed are at a higher risk for progression into malignancy. [contourderm.com]

The distinction between the two lesions is of importance as Bowen's disease represents a precancerous dermatosis and bowenoid papulosis a probably benign lesion of viral etiology. [unboundmedicine.com]

Evidence supports an etiologic role of human papillomavirus (HPV), particularly type 16. HPV-16 is also associated with an increased risk for cervical intraepithelial neoplasia (CIN) and invasive carcinoma. [ncbi.nlm.nih.gov]

[…] penile intraepithelial neoplasia (males) or vulvar intraepithelial neoplasia (females) Epidemiology Preferentially affects sexually active young males (mean age 30 years) Sites Primarily penile shaft; may also be present in foreskin, glans or scrotum Etiology [pathologyoutlines.com]

[…] bowenoid papulosis progressing to Bowen's disease. [3] According to Wade there is a potential for bowenoid papulosis to become invasive squamous cell carcinoma and he advises complete removal of the lesion. [3] From the earlier description onwards the etiology [ijdvl.com]

Recommend to your librarian Human papilloma virus (HPV) is known to be an etiologic agent for benign warts of the skin. [f1000.com]

The discovery of a possible oncogenic virus in BP and the epidemiologic behavior of carcinoma in situ and multicentric carcinomas suggest the need for a very careful follow-up evaluation of such lesions. [ncbi.nlm.nih.gov]

Terminology Type of penile intraepithelial neoplasia (males) or vulvar intraepithelial neoplasia (females) Epidemiology Preferentially affects sexually active young males (mean age 30 years) Sites Primarily penile shaft; may also be present in foreskin [pathologyoutlines.com]

Epidemiology Frequency Bowenoid papulosis lesions are related clinically to genital warts. They share the same age of onset in patients and are transmitted sexually. [emedicine.com]

Pathophysiology Bowenoid papulosis is an asymptomatic focal epidermal hyperplasia and dysplasia induced by HPV infection [1, 2] (most commonly by HPV 16). [emedicine.com]

Pathophysiology and clinical presentation of rectal cancer-induced FG per se does not differ from the other causes. Only rectal cancer-specific symptoms before presentation can lead to the diagnosis. [science.gov]

Prevention - Bowenoid papulosis Not supplied. Diagnosis - Bowenoid papulosis Not supplied. Prognosis - Bowenoid papulosis The condition usually resolves itself with time but they should be regularly checked due to the risk of malignancy. [checkorphan.org]

Luckily there exists a vaccine – Gardasil – that both young boys and girls may receive which prevents infection from certain HPV strains that are most likely to lead to cancer. [contourderm.com]

New HPV vaccines have been approved and recommended by the CDC to help prevent cervical cancer in women. [aocd.org]

ABSTRACT: Copy: The injectable adipocytolytic drug deoxycholic acid (DCA) is the f... more The Role of Topical Retinoids in Prevention and Treatment of Atrophic Acne .... ABSTRACT: Atrophic acne scarring is a frequent occurrence among acne patients. [jddonline.com]

A patient with BP should be thoroughly educated regarding HPV infection and emphasis should be on prevention. [cdriadvlkn.org]

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