Presentation
The author presents two patients suffering from brachioradial pruritus who were treated with thalidomide and presented excellent results. This paper aims to suggest a new therapeutic option for this refractory disease. [scielo.br]
Neuropathic pruritus can present clinically as brachioradial pruritus or notalgia paresthetica. Showing page 1. Found 4 sentences matching phrase "Brachioradial pruritus".Found in 1 ms. [glosbe.com]
A total of 58 consecutive patients presenting at the Center for Chronic Pruritus, University Hospital Münster, were analysed with regard to clinical presentation, anatomical and morphological pathologies, impairment in quality of life, and response to [read.qxmd.com]
Cervical magnetic resonance imaging should be performed if the onset is recent or neurologic deficits are present. The region around the C5 and C6 nerve roots, in particular, should be analyzed. [dermatologyadvisor.com]
We present a patient with brachioradial pruritus and a review of the literature. [mdedge.com]
Workup
Further workup, such as imaging, labs, and referral to specialists is rarely required. Therapeutic options are numerous and well-tolerated. [ncbi.nlm.nih.gov]
And you should never just dismiss a very persistent symptom—even if it seems like no big deal—without a proper workup. Below are some reasons you may be feeling itchy, even when there is no rash present. 1. [self.com]
Treatment
Shorter treatment durations were associated with worse perceptions of reduction (χ2; p=0.0004). Higher intensities of pruritus prior to treatment were associated with excellent reduction after treatment (KW; p=0.0376) (Figure 1b). [scielo.br]
Mean inpatient treatment costs were reduced by €212.31, and mean outpatient treatment and medication costs by €100.74 per patient (p.p.). [tripdatabase.com]
Cutaneous Field Stimulation in the Treatment of Severe Itch. Arch Dermatol. 2001;137:1232-1325. doi:10.1001/archderm.137.10.1323. Stellon A. Neurogenic pruritus: An unrecognised problem? A retrospective case series of treatment by acupuncture. [jofskin.org]
Other treatments of neuropathic pain and itching, including capsaicin, amitriptyline, and gabapentin, can sometimes be successful. 5, 12, 13 Many patients are refractory to multiple treatments. [ncbi.nlm.nih.gov]
Prognosis
What is the prognosis (outlook) for itching? Itching itself is not associated with long-term skin problems or harm, and most cases of itch are temporary and resolve on their own or with topical or oral treatments. [medicinenet.com]
Etiology
Often described as dermatologic syndromes, both diseases are typically considered to be multifactorial in etiology with an uncertain etiology... [read.qxmd.com]
History and Physical Because pruritus has many etiologies, a thorough history is essential to avoid unnecessary testing and delay in treatment. [ncbi.nlm.nih.gov]
It is likely that the etiology of BRP is not uniform and both of the above factors contribute to varying degrees in different patients. [dermatologyadvisor.com]
Aimee Szewka, Michael Gibbs, Jonathan Cheponis, Steven Lewis First published April 4, 2016, Abstract OBJECTIVE: To report three cases of brachioradial pruritus (BRP), describe the typical clinical presentation and epidemiology, and discuss possible etiology [n.neurology.org]
Some of the current systemic therapies may in fact exert their effect through the spinal nerves and central nervous system thereby supporting the neuropathic etiology of BRP( Brachioradial Pruritus). [lagunaskincenter.com]
Epidemiology
86 (16 Supplement) April 18, 2016 Aimee Szewka, Michael Gibbs, Jonathan Cheponis, Steven Lewis First published April 4, 2016, Abstract OBJECTIVE: To report three cases of brachioradial pruritus (BRP), describe the typical clinical presentation and epidemiology [n.neurology.org]
The emergence of brachioradial pruritus cases in temperate climates has further contributed to research efforts to discover more about the epidemiology of this neurocutaneous condition. [wisegeek.com]
Epidemiology Early isolated case reports suggested that brachioradial pruritus was more common in males. Later larger studies revealed that brachioradial pruritus is seen more commonly in females than males in a ratio 3:1. [ncbi.nlm.nih.gov]
Epidemiology Affects Caucasians living in tropical regions More common in middle-aged women III. Pathophysiology: Postulated Mechanisms with nerve compression Prolonged ultraviolet light exposure (e.g. tropics) IV. [tripdatabase.com]
Pinto ACVD, Masuda PY, Wachholz PA, Carlos A, Martelli C. clinical, epidemiological and therapeutic profile of patients with brachioradial pruritus in a reference service in dermatology. An Bras Dermatol. 2016;91(4):549-551. Mirzoyev SA, Davis MDP. [jofskin.org]
Pathophysiology
In view of the literature, a definitive pathophysiology for brachioradial pruritus does not exist. It is clear that it is a unique clinical entity, but the pathophysiologic basis is not known. [mdedge.com]
Pathophysiology: Postulated Mechanisms with nerve compression Prolonged ultraviolet light exposure (e.g. tropics) IV. [tripdatabase.com]
[…] supporting the solar hypothesis Many patients with brachioradial pruritus have a history of chronic sun exposure. [2, 14, 15] Kestenbaum and Kalivas [16] postulated that histamine release from mast cells in response to chronic sun exposure might play a pathophysiologic [emedicine.medscape.com]
Recent advances in pathophysiology and current management of itch. Ann Acad Med Singapore 2007;36:788-92 7. Wallengren J. Brachioradial pruritus: a recurrent solar dermopathy. J Am Acad Dermatol 1998;39:803-6. 8. Wallengren J Sundler F. [content.sciendo.com]
The lack of primary skin lesions in brachioradial pruritus in addition to its poorly established pathophysiology can often lead to both diagnostic and therapeutic challenges for many physicians. [read.qxmd.com]
Prevention
Prevent the condition from worsening In Australia, most cases result from sun damage to sensory nerves and sun protection to prevent summertime worsening is important. [dermcoll.edu.au]
The best way to prevent pruritus is to take care of your skin. To protect skin: Use skin creams and lotions that moisturize your skin and prevent dryness. Use sunscreens regularly to prevent sunburns and skin damage. [webmd.com]
Source: iStock Is it possible to prevent itching? Itching can be prevented only to the extent that the underlying cause(s) of the itching sensation can be prevented. [medicinenet.com]
[…] initially diagnosed on the appearance of symptoms, but other testing is required to determine the causative factor, including radiological, imaging, nerve testing, and Skin biopsy Treatment *Treatment is not always successful *Goal of treatment is to prevent [ozarkderm.com]
Targeting these damaged nociceptors and preventing them from firing can potentially lead to symptomatic improvement. [cureus.com]