Presentation
Abstract The most common cardiovascular presentation of brucellosis (a zoonotic infection) in Iran is aortic valve endocarditis. [ncbi.nlm.nih.gov]
Entire Body System
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Atrial Septal Defect
We report brucella endocarditis in an atrial septal defect (ASD) in a 55-year-old man who presented with fever and hemiplegia. Echocardiography showed a secundum ASD with large vegetations of 0.5 1 cm arising from the rim of the ASD. [ncbi.nlm.nih.gov]
Gastrointestinal
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Regurgitation
Echocardiography showed severe aortic regurgitation, moderate mitral regurgitation, severe left ventricular dysfunction and a mobile vegetation attached to the aortic valve. [ncbi.nlm.nih.gov]
Liver, Gall & Pancreas
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Jaundice
We present the case of a 47-year-old Egyptian man, with hepatitis C cirrhosis, and a 2 week history of ascites, jaundice, encephalopathy, fever and pain on his right shoulder that started while travelling in the Middle East. [ncbi.nlm.nih.gov]
Cardiovascular
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Diastolic Murmur
Cardiac auscultation revealed the presence of a diastolic murmur. Subsequently, a cardiac echocardiogram was done, which showed a large vegetation adherent to an anterior mitral leaflet. The blood culture was positive for Brucella species. [ncbi.nlm.nih.gov]
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Chest Pain
A 32-year-old Caucasian man with acute chest pain was examined at Sfax Hedi Chaker's Hospital. He had a night fever, although his cardiac examination was normal. [ncbi.nlm.nih.gov]
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Left Ventricular Dysfunction
Echocardiography showed severe aortic regurgitation, moderate mitral regurgitation, severe left ventricular dysfunction and a mobile vegetation attached to the aortic valve. [ncbi.nlm.nih.gov]
Skin
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Ulcer
The patient was treated with doxycycline, rifampicin, and gentamicin, and underwent surgical repair of a penetrating aortic ulcer, with a good clinical recovery. [ncbi.nlm.nih.gov]
Urogenital
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Testicular Pain
testicular pain, tenderness and scrotal swelling), a positive Rose Bengal test result, standard tube agglutination (STA) titer 1/160, and/or a positive blood culture. [ncbi.nlm.nih.gov]
Neurologic
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Aphasia
Abstract A 55-year-old male presented with fever, stupor, aphasia, and left hemiparesis. A history of head trauma 3 months before was also reported. [ncbi.nlm.nih.gov]
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Encephalopathy
We present the case of a 47-year-old Egyptian man, with hepatitis C cirrhosis, and a 2 week history of ascites, jaundice, encephalopathy, fever and pain on his right shoulder that started while travelling in the Middle East. [ncbi.nlm.nih.gov]
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Stupor
Abstract A 55-year-old male presented with fever, stupor, aphasia, and left hemiparesis. A history of head trauma 3 months before was also reported. [ncbi.nlm.nih.gov]
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Neurologic Manifestation
Subacute and chronic meningoencephalitis are described as the most common neurologic manifestations. We report a six-year-old boy with culture-proven neurobrucellosis who presented with an acute picture of meningoencephalitis. [ncbi.nlm.nih.gov]
Workup
X-Ray
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Calcified Aortic Valve
His two-dimensional (2D) echocardiogram revealed a calcified aortic valve with mild aortic stenosis. [ncbi.nlm.nih.gov]
Treatment
(34.21copies/μl) on 21st day after treatment depicting a significant reduction in DNA load over the course of treatment. [ncbi.nlm.nih.gov]
Prognosis
We review the signs and symptoms, diagnostic approach, prognosis, and treatment of brucella arteritis. [ncbi.nlm.nih.gov]
The prognosis for patients with brucellar myopericarditis is usually favorable, as it was for the patient presented in this report. [revespcardiol.org]
The worst prognosis was observed for patients with panuveitis and posterior uveitis ( table 5 ). Table 5 Visual prognosis of uveitis. Table 5 Visual prognosis of uveitis. [academic.oup.com]
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. Front Cell Infect Microbiol 2 : 1 – 6. 26. Falenski A ,, Mayer-Scholl A ,, Filter M ,, Golner C ,, Appel B ,, Nockler K. 2011. [asmscience.org]
[…] optimization of treatment adherence, the monitoring for potential adverse effects, the importance of expert consultation in complicated disease, and the importance of a good relationship between patients and physicians, which is essential for a better prognosis [doi.org]
Etiology
MESSAGE: Brucellosis should be considered as an etiology of liver abscess in patients not responding to conventional antibiotics. [ncbi.nlm.nih.gov]
which would then require subsequent diagnostic tests to identify the etiologic agent. [dx.doi.org]
have been linked to a number of syndromes of as yet unknown etiology, which include fibromyalgia, CFS, and sarcoidosis ( 4, 6, 14 ), it will be of interest to investigate the potential role of Brucella sp. infection in such syndromes. [jcm.asm.org]
Epidemiology
The charts and map were processed by Excel 2013, and cluster analysis and epidemiological distribution was performed using BioNumerics (version 5.1). [ncbi.nlm.nih.gov]
Pathophysiology
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Brucella species are facultative intracellular Gram-negative staining bacilli capable of producing the disease "brucellosis" [mayomedicallaboratories.com]
Various trials have been performed with combinations omitting such a compound, often reporting adequate results; yet understanding the pathophysiology of the disease renders the inclusion of tetracyclines imperative. [doi.org]
Prevention
On February 10, 2012, the Maine Center for Disease Control and Prevention (Maine CDC) was notified of a positive Brucella culture from a harbor porpoise (Phocoena phocoena) found on the coast of southern Maine. [ncbi.nlm.nih.gov]