Presentation
Seventy-seven (13%) individuals showed lymphedema of the leg that occasionally presented severe elephantiasis. No hydrocele or genital lymphedema were observed. [ncbi.nlm.nih.gov]
Our presentation revealed that adult female worm and microfilaria may even be present at rare sites such as submandibular region. [jcytol.org]
Individuals with Brugia Timori Infection commonly present with no symptoms. [dovemed.com]
Entire Body System
- Lymphedema
Seventy-seven (13%) individuals showed lymphedema of the leg that occasionally presented severe elephantiasis. No hydrocele or genital lymphedema were observed. [ncbi.nlm.nih.gov]
Also, the sheath of B. timori does not stain pink with Giemsa stain as is observed with B. malayi and W. bancrofti. [ 4 ] Brugia timori filariasis Like other human filariasis infections, Brugia timori filariasis causes acute fever and chronic lymphedema [dictionnaire.sensagent.leparisien.fr]
Also, the sheath of B. timori does not stain pink with Giemsa stain as is observed with B. malayi and W. bancrofti. [4] Brugia timori filariasis Like other human filariasis infections, Brugia timori filariasis causes acute fever and chronic lymphedema [ipfs.io]
This obstruction results in lymphedema of the legs, arms, breasts, and/or genitalia. Male genital involvement such as hydrocele is very common in W. bancrofti infection but uncommon in Brugia species infection. [clinicalgate.com]
Also, the sheath of B. timori does not stain pink with Giemsa stain as is observed with B. malayi and W. bancrofti.[4] Brugia Timori Filariasis Like other human filariasis infections, Brugia timori filariasis causes acute fever and chronic lymphedema. [wikidoc.org]
- Inflammation
Anti-inflammatory agents may be used to reduce the extent of inflammation, and elastic support stockings can be helpful in reducing moderate lymphedema. [antiinfectivemeds.com]
Acute episodes of local inflammation involving skin, lymph nodes and lymphatic vessels. Some inflammation is caused by the immune system response to the parasite, but some is largely the result of bacterial skin infection. [cdc.gov.tw]
These may include fever and inflammation surrounding infected lymph nodes. [dovemed.com]
Lymphatic filariasis is rarely fatal, but it can cause recurring infections, fevers, severe inflammation of the lymph system, and a lung condition called tropical pulmonary eosinophilia (TPE). [web.archive.org]
and endocarditis (inflammation of the lining of the heart). [brighterdayfoods.com]
- Malaise
Fever, chills, vomiting, headache, and malaise may be associated with lymphangitis of an extremity, orchids, epididymitis, or scrotal swelling. The affected extremity becomes hot, swollen, erythematous, and painful, mimicking cellulitis. [antiinfectivemeds.com]
Patients suffer repeated episodes including systemic symptoms like fever and general malaise. Localized enlargement of lymph nodes draining the affected body parts appears. [antimicrobe.org]
The adverse effects in the doxycycline group (n=119) were myalgia (n=6), nausea (n=4), dizziness (n=5), headache (n=3), insomnia (n=2), abdominal pain (n=2), itching (n=2), diarrhea (n=1), rash (n=1), malaise (n=1), and drowsiness (n=1); in the placebo [academic.oup.com]
Gastrointestinal
- Diarrhea
The adverse effects in the doxycycline group (n=119) were myalgia (n=6), nausea (n=4), dizziness (n=5), headache (n=3), insomnia (n=2), abdominal pain (n=2), itching (n=2), diarrhea (n=1), rash (n=1), malaise (n=1), and drowsiness (n=1); in the placebo [academic.oup.com]
Avoid with diarrhea or high or low blood pressure. Avoid taking pomegranate fruit husk with oil or fats to treat parasites. Pomegranate root/stem bark should only be used under the supervision of a qualified healthcare professional. [brighterdayfoods.com]
- Nausea
[…] group (n=42), adverse effects were myalgia (n=2), nausea (n=1), dizziness (n=2), insomnia (n=1), and itching (n=1). [academic.oup.com]
These sorrel formulations may cause nausea or vomiting when taken with the prescription drugs metronidazole (Flagyl®) or disulfiram (Antabuse®). Avoid if pregnant or breastfeeding. [brighterdayfoods.com]
- Vomiting
Fever, chills, vomiting, headache, and malaise may be associated with lymphangitis of an extremity, orchids, epididymitis, or scrotal swelling. The affected extremity becomes hot, swollen, erythematous, and painful, mimicking cellulitis. [antiinfectivemeds.com]
These sorrel formulations may cause nausea or vomiting when taken with the prescription drugs metronidazole (Flagyl®) or disulfiram (Antabuse®). Avoid if pregnant or breastfeeding. [brighterdayfoods.com]
Skin
- Skin Thickening
Persistent lymphatic obstruction and edema lead to marked skin thickening and deposition of collagenous material, eventually causing elephantiasis. [antiinfectivemeds.com]
Workup
Microbiology
- Brugia Malayi
Médard Athlétisme Bruges, Belgium Bruges, Belgium Bruges, Belgium Brugge Brugge Brugge Brügge Brügge Brügge Brugge, Belgium Brugge, Belgium Brugge, Belgium Brugges Brugges Brugges brugh Brugia Brugia filariasis Brugia malayi Brugia Malayi Microfilarial [medical-dictionary.thefreedictionary.com]
Abstract The microfilaria of Brugia timori was compared with microfilariae of Indonesian strains of periodic and subperiodic Brugia malayi using alcohol-fixed (stained) and formalin-fixed (unstained) preparations. [pubmed.ncbi.nlm.nih.gov]
The microfilariae of Brugia timori are longer and morphologically distinct from those of Brugia malayi and Wuchereria bancrofti, with a cephalic space length-to-width ratio of about 3:1. [dictionnaire.sensagent.leparisien.fr]
[…] microfilariae of Brugia timori are longer and morphologically distinct from those of Brugia malayi and Wuchereria bancrofti, with a cephalic space length-to-width ratio of about 3:1. [ipfs.io]
- Wuchereria Bancrofti
The major offending organisms in lymphatic filariasis are Wuchereria bancrofti and Brugia malayi or Brugia timori. Of these, Wuchereria bancrofti is the most prevalent species. [medical-dictionary.thefreedictionary.com]
LF is caused by three major nematodes namely Wuchereria bancrofti, Brugia malayi, and Brugia timori. [unboundmedicine.com]
The life cycle of Brugia timori is very similar to that of Wuchereria bancrofti and Brugia malayi, leading to nocturnal periodicity of the disease symptoms. So far Brugia timori has only been found in the Lesser Sunda Islands of Indonesia. [dictionnaire.sensagent.leparisien.fr]
Treatment
Re-infection with A. lumbricoides may return six months after treatment to almost 90% of the pre-treatment prevalence and worm density may drop to about 75% [ 35 ]. [filariajournal.com]
One year after treatment 69 subjects (72%) were mf-negative and the overall geometric mean mf density reduced to 3 mf/mL (0-2456 mf/mL). The reduction of mf was more pronounced 1 year after treatment compared with 6 months after treatment. [ncbi.nlm.nih.gov]
[…] and DEC–Alb treatments (P = 0.527). [onlinelibrary.wiley.com]
Prognosis
(Outcomes/Resolutions) The prognosis for Brugia Timori Infection is generally quite good, as those with early to mild infection may be asymptomatic Treatment with DEC has proved to be effective in eliminating the infection It is currently not possible [dovemed.com]
Etiology
The etiological diagnosis is mainly based on detection and visualization of the microfilarias, in blood or skin. [medicineonline.es]
(Etiology) Brugia Timori Infection is caused by the parasitic roundworm Brugia timori. [dovemed.com]
Epidemiology
Abstract The epidemiological and clinical features of Brugia timori filariasis in a newly established village, Karakuak, West Flores, is described. [ncbi.nlm.nih.gov]
Epidemiological and clinical features of Brugia timori in a newly established village, Karakuak, West Flores, Indonesia. Am. J. Trop. Med. Hyg. 1978; 27: 910-915 Partono F et al. [cell.com]
The epidemiology and treatment of infection due to Brugia malayi. Bull World Health Organ. 1962;27(4–5):529–41. Google Scholar Okon OE, Iboh CI, Opara KN. Bancroftian filariasis among the Mbembe people in Cross River State, Nigeria. [link.springer.com]
Abstract Abstract The epidemiological and clinical features of Brugia timori filariasis in a newly established village, Karakuak, West Flores, is described. [ajtmh.org]
While classical cases of filariasis are common and hence dealt at epidemiologic scales, uncommon infections are largely neglected and reported rarely. [tropicalparasitology.org]
Prevention
How can lymphatic filariasis be prevented? There is no vaccine for filariasis. [web.archive.org]
For individuals with this condition, proper care of the limb must be taken to prevent infection. Additional steps may be taken to lessen the effects of swelling. [dovemed.com]
Epidemiology Currently, 856 million people in 52 countries worldwide remain threatened by lymphatic filariasis and require preventive chemotherapy to stop the spread of this parasitic infection. [cdc.gov.tw]
Tea tree oil : Tea tree oil is purported to have antiseptic properties, and has been used traditionally to prevent and treat infections. [brighterdayfoods.com]
Health benefits of corn include diabetes management, and prevention of heart con... Check it out, Arepa Café has been featured in Narcity! “They Serves Up ... Watercress is a dark, leafy green grown in natural spring water. For the past fe... [arepacafe.ca]