At present patient is in remission and following up with us on regular basis. [jemds.com]

In the present case only oral involvement could be appreciated at the time of initial presentation. [idoj.in]

Proceedings of the Royal Society of Medicine 22(8): 1013-1014, 1929 Lichen planus presenting with erythema-multiforme-like bullous lesions in a patient with systemic scleroderma. [eurekamag.com]

Nail LP presents in 10 to 25 percent of LP patients and tends to present as roughness, vertical ridges or cracks, and thinning of the nail. This can eventually lead to scarring of the nail. [rarediseases.org]

A clinical case of a female patient presenting a white macula erythematous areas with irregular borders with six month history of symptomatic is presented. [medigraphic.com]

• Yellow Nails

  […] mimicking yellow nail syndrome. ( 6627735 ) Haneke E. 1983 31 Immunofluorescent findings in oral bullous lichen planus. ( 383916 ) Goldstein B.H....Katz S.M. 1979 32 Bullous lichen planus caused by labetalol. ( 346143 ) Gange R.W....Jones E.W. 1978 33 [malacards.org]

• Anhidrosis

  Sometimes degeneration (atrophy) of the skin may occur as lesions persist (atrophic LP) and some patients experience an absence of sweating due to degeneration of sweat glands (anhidrosis). [rarediseases.org]

• Receding Hairline

  When and if hair loss does occur, it can involve small patchy areas of the scalp (atrophic cictrical alopecia) or cause a receding hairline (frontal fibrosing alopecia). Due to scarring, this hair loss is permanent if untreated. [rarediseases.org]

• Incontinence

  (a) Appearance of subepidermal clefting due to extensive basal cell vacuolation and lymphocytic infi ltrate hugging the epidermis (H and E, ×10) (b) High power view revealing clefting, pigment incontinence and dermal melanophages (H and E, ×40) Click [ijdvl.com]

  […] typically show histopathologic features indistinguishable from those of lichen planus: orthokeratosis, hypergranulosis, irregularacanthosis, basal cell hydropic degeneration with cytoid body formation, dense chronic inflammatory infiltration and pigment incontinence [jemds.com]

  Infrequently poikilodermatous features can be an additional with dilated superficial blood vessels and pigment incontinence. [bioline.org.br]

  […] found at the lower dermis and superficial epidermis.[ 20 ] Vacuolar degeneration of the basal layer is typical and results in separated spaces between the epidermis and the dermis, known as "Max-Joseph spaces".[ 21 ] Often there is presence of pigment incontinence [ncbi.nlm.nih.gov]

• Insomnia

  As the patient complained of insomnia caused by low-dose corticosteroid therapy, CyA administration was considered, although an increase in the dose of PSL would have been the standardized therapeutic strategy. [karger.com]

[…] immunoglobulin A [IgA]) and complement Linear or shaggy deposits of fibrin and fibrinogen in the basement membrane zone In the upper dermis, a bandlike infiltrate of lymphocytic (primarily helper T) and histiocytic cells with many Langerhans cells See Workup [emedicine.medscape.com]

A 4-mm punch biopsy of perilesional skin for direct immunofluorescence may be added to the workup when bullous lesions, pemphigus, or bullous pemphigoid is present. [aafp.org]

There is no established treatment for BLP. [ncbi.nlm.nih.gov]

We thus expect that several novel treatments will be shortly available for the treatment of pemphigus and pemphigoid patients. [medworm.com]

It resembles bullous pemphigoid, but carries a better prognosis. [medcaretips.com]

Prognosis [ 1 ] Spontaneous resolution of cutaneous lesions usually occurs over a period of 6 to 12 months but hypertrophic lesions can last for years. Oral lesions usually have a chronic and progressive course and may never completely resolve. [patient.info]

Prognosis and outcome The prognosis for spontaneous remission of erosive vulvovaginal lichen planus is poor. Despite a number of available therapies, significant control of symptoms and restoration of sexual function remain difficult. [cancertherapyadvisor.com]

Clinically, histopathologically and immunopathologically, it has features of lichen planus and bullous pemphigoid, it but carries a better prognosis than pemphigoid. [emedicine.medscape.com]

Etiology Etiology is unknown. The documents contained in this web site are presented for information purposes only. [orpha.net]

Etiology of Periodontal Diseases (Part 4) provides a more comprehensive background in periodontal anatomy, physiology, and pathogenesis. [books.google.com]

DIFINETION CHRINIC INFLAMMATORY DISEASE OF UNKNOW ETIOLOGY CHARECTRISED BY ------ SHINY VIOLACEOUS ITCHY FLAT TOPPED PAPULAR LESIONS MORPHOLOGICALLY & HISTOLOGICALLY CHARECTERISED BY -------- Download Presentation An Image/Link below is provided (as is [slideserve.com]

Discussion LSA is a rare, chronic, mucocutaneous disorder of unknown etiology. It is predominantly present in women, with a female : male ratio of 5 : 1 and may occur at any age. [ejdv.eg.net]

Although the etiology of bullous LSA remains obscure, many factors have been suggested. [scielo.br]

Summary Epidemiology Prevalence is unknown and only a few cases, both sporadic and familial, have been described in the literature. Clinical description The disease manifests during childhood or adolescence. [orpha.net]

Lichen planus: A clinical and epidemiological study. J Dermatol 2000;27:576-82. 2. Harjai B, Mendiratta V, Kakkar S, Koranne RV. Childhood lichen planus pemphigoides-A rare entity. J Eur Acad Dermatol Venereol 2006;20:117-8. [ PUBMED ] 3. [ijdvl.com]

Epidemiology The incidence of pemphigoid in the UK is estimated at 4.3 per 100,000 persons per year. [ 3 ] In other parts of Europe the incidence is 0.7-1.3 per 100,000. [patient.info]

Epidemiology The exact prevalence of BLP remains unknown. The disease is usually sporadic. [ncbi.nlm.nih.gov]

Image Credit Pathophysiology of Lichen Planus The exact cause of lichen planus is not known, although it is immunologically mediated. The initiating antigen is unclear. [medcaretips.com]

Vulvar lichen sclerosus: Pathophysiology and treatment. Am J Clin Dermatol 2004;5:105-25. [ PUBMED ] 4. Iraji F, Schofield O. [e-ijd.org]

Nikolsky's observations were later confirmed by Lyell in 1956, who described a Nikolsky's sign in patients with toxic epidermal necrolysis. [9] Pathophysiology The pathophysiology associated with Nikolsky's sign is the acantholysis [8] i.e., loss of coherence [jiaomr.in]

"Pathophysiology, etiologic factors, and clinical management of oral lichen planus, part I: facts and controversies". Clinics in Dermatology. 28 (1): 100–8. doi : 10.1016/j.clindermatol.2009.03.004. [en.wikipedia.org]

Lichen planus is a chronic, inflammatory, autoimmune disease 1 occurring in 0.1 to 4 percent of the general population, most often in perimenopausal women. 2 Lichen planus can appear at any age, but most cases occur between 30 and 60 years of age. 2 Pathophysiology [aafp.org]

The information presented here is not intended to diagnose, treat, cure or prevent any disease. Read disclaimer. [gulfdoctor.net]

IMAGES Lichen Planus See a picture of lichen planus and other skin eruptions See Images Is it possible to prevent lichen planus? Since the cause of lichen planus is unknown, there are no reliable options to prevent it. [medicinenet.com]

Further development of scars and adhesions can be prevented with regular use of dilators as demonstrated in a number of prospective studies. Coating the dilator with either steroid ointment or vaginal estrogen cream is recommended. [cancertherapyadvisor.com]

However, despite a limited comprehension of the pathogenesis of OLP, therapeutic stratagems are being pursued, based on this understanding, including the trialling of TNF-α inhibitors, interleukin-1 inhibitors, mast cells stabiliser agents, to prevent [intechopen.com]