She also complained of arthralgia about 2 months ago, fatigue and weight loss of 10 kg. Physical examination revealed a malar rash and blisters affecting the abdomen and upper limbs ( Figure 1, Figure 2 ). [em-consulte.com]

Clinical features Relatively common autoimmune disease of women, due to anti-DNA antibodies Fatigue, fever, arthritis, erythematous, bilateral butterfly (malar) rash of the face, renal disease, lymphadenopathy, and serositis Associated with altered immunity [pathologyoutlines.com]

Continued Sometimes, changes in blood counts (low red cell count, or anemia ), may cause fatigue, serious infections (low white cell count), or easy bruising or bleeding (low platelet count). [webmd.com]

"Treatment and management of chronic fatigue syndrome/myalgic encephalomyelitis: All roads lead to Rome". British Journal of Pharmacology. 174 (5): 345–369. doi : 10.1111/bph.13702. PMC 5301046. PMID 28052319. [en.wikipedia.org]

Jones DA, Hunt SW, 3rd, Prisayanh PS, Briggaman RA, Gammon WR. Immunodominant auto-epitopes of type VII collagen are short, paired peptide sequences within the fibronectin type III homology region of the noncollagenous (NC1) domain. [ncbi.nlm.nih.gov]

Hunt 3rd, P.S. Prisayanh, R.A. Briggaman, W.R. [elsevier.es]

There is also associated complain of itching and photophobia but no complaint of fever or joint pain or history suggestive of Raynaud's phenomenon, or butterfly rash was revealed. Birth history and family history were nonsignificant. [ijpd.in]

In toxic epidermal necrolysis–like acute cutaneous lupus erythematosus, photodistributed diffuse or patchy erythema evolves (usually rapidly) into flaccid bullae (positive Nikolsky sign, unlike bullous systemic lupus erythematosus) and widespread, sheetlike [emedicine.medscape.com]

Bulla spreading and Nikolsky's signs were negative. Raw oozing and crusted lesions were also present. Atrophic patches, hypo-and hyperpigmented areas were also present. Carpet tack sign was positive. [ijdvl.com]

Nikolsky's sign was negative. Multiple postinflammatory scaly patches were seen over trunk and extremities. Scarring was absent. Hair and nail examination was within normal limit. No malar rash was seen. [ijpd.in]

Bulla spread sign and Nikolsky sign were positive. In addition, superficial erosions, areas of postinflammatory hyperpigmentation, and small superficial scars were noted. [ncbi.nlm.nih.gov]

Examination of the skin was remarkable for numerous flaccid hemorrhagic bullae on a normal-appearing nonerythematous skin involving both the upper and lower extremities. [karger.com]

A 31-yr-old woman presented with generalized erythematous patches, multiple bullae, arthralgia, fever, conjunctivitis, and hemolytic anemia. [ncbi.nlm.nih.gov]

She also complained of arthralgia about 2 months ago, fatigue and weight loss of 10 kg. Physical examination revealed a malar rash and blisters affecting the abdomen and upper limbs ( Figure 1, Figure 2 ). [em-consulte.com]

The latter include a photoinduced skin rash, arthralgia, arthritis, fever, Raynaud's phenomenon, anemia, leukopenia, serositis, nephritis and central nervous sysdtem disease. [researchgate.net]

She denied arthralgias, photosensitivity, fevers or chills, cough, sore throat, hemoptysis, diarrhea or vomiting, epistaxis, hematemesis, or melena. [karger.com]

Extracutaneous findings of systemic lupus erythematosus may include joint tenderness and swelling, pallor or petechiae (reflecting hematologic abnormalities), and auscultation evidence of a pulmonary or pericardial effusion. [emedicine.medscape.com]

However, the cause of death in the latter case could be related to an APS relapse when the patient developed what has been called "catastrophic APS" after low-dose aspirin was inadvertently withdrawn. [ped-rheum.biomedcentral.com]

Over the next 6 months, steroids were completely withdrawn, and dapsone and hydroxychloroquine continued for further 1 year. The patient has remained in remission without any systemic manifestations as well, over the last 1 year. [ncbi.nlm.nih.gov]

However, the renal biopsy could not be performed because of the denial from the patient's family. Skin biopsy from these bullous lesions revealed subepidermal cleft with a few neutrophil and eosinophils [Figure 3] and [Figure 4]. [ijpd.in]

Risk factors for this side effect include drug interactions (trimethoprim/sulfamethoxazole [TMP/SMX] and NSAIDS), renal insufficiency, older age ( 65) and no folate supplementation. [dermatologyadvisor.com]

We report a case of a 12-year-old girl who presented with a vesiculobullous eruption on her face, neck, trunk and genital and oral mucosa, as well as anemia, sterile pyuria, ANA (1:1280, speckled pattern) and positive anti-Sm and anti-RNP. [ncbi.nlm.nih.gov]

The blood tests revealed neutropenia (leukocytes 3300/mm 3 and neutrophils 2000/mm 3 ), Uremia at 3.17 g/L, creatinine at 89 mg/L, serum potassium to 7.03 meq/L and albuminuria at 3.4 g/L. [em-consulte.com]

Cessation of dapsone therapy due to hemolysis with Heinz-body formation did not aggravate the bullous disease. Our case illustrates that a generalized vesiculobullous eruption can be the sole presenting manifestation of SLE. [ncbi.nlm.nih.gov]

No mucin or viral inclusion body is seen. Direct immunofluorescence showed granular IgA and IgG deposition along dermo-epidermal junction with IgG IgA. Also, perivascular IgG deposition was seen in the dermis. She was diagnosed to have BSLE. [ijpd.in]