Presentation
We present a case of intentional caffeine poisoning in a 5-week-old infant and review treatment. This infant later suffered fatal physical abuse. [pediatrics.aappublications.org]
Case presentation A 32-year-old woman with no significant medical and family history presented to the local emergency department (ED) referring malaise, anxiety, dizziness and nausea. [casereports.bmj.com]
Indeed, many patients present at ages or with histories incompatible with “accidental” ingestion, others may even present with histories of recurrent illnesses suggesting previous undiagnosed poisonings. [ncbi.nlm.nih.gov]
Respiratoric
- Aspiration
Those who do not seek treatment or the treatment is delayed may develop seizures, arrhythmias or even aspirate the vomitus. Over the past decade, less than 3 dozen deaths have been reported. [ncbi.nlm.nih.gov]
Gastrointestinal
- Nausea
Symptoms include restlessness, anxiety, general depression, tachycardia, arrhythmias (premature atrial contractions), tremors, nausea, diuresis, and insomnia. [medical-dictionary.thefreedictionary.com]
Case presentation A 32-year-old woman with no significant medical and family history presented to the local emergency department (ED) referring malaise, anxiety, dizziness and nausea. [casereports.bmj.com]
Most of the time, if individuals have severe signs of caffeine toxicity, it starts with nausea and vomiting. So that is somewhat protective because you get sick and throw up the caffeine before it gets too toxic. [modernheartandvascular.com]
Ears
- Tinnitus
And in toxic doses, caffeine directly releases calcium from intracellular stores, which also may increase the susceptibility for arrhythmias. 8 Symptoms of caffeine intoxication may include headache, fever, nausea, vomiting, tachycardia, dizziness, tinnitus [casereports.bmj.com]
Neurologic
- Agitation
Reportedly he had been fine earlier in the day, but on the mother's return home, she noticed that he was agitated and irritable. The father attributed the change to a 1-year-old sibling having sat on the child's chest. [pediatrics.aappublications.org]
After observation, the patient had an episode of presyncope followed by agitation and vomiting. [casereports.bmj.com]
Symptoms associated with high doses of caffeine include muscle twitching, rambling flow of thought and speech, tachycardia and cardiac arrhythmia, periods of inexhaustibility, and psychomotor agitation,[1] anorexia (loss of appetite). [en.wikipedia.org]
A neurologic exam may demonstrate altered mentation, agitation, delusional thought, hallucinations, seizures or even focal neurologic findings thought to be due to ischemia from vasoconstriction. [ncbi.nlm.nih.gov]
- Intracranial Hemorrhage
hemorrhage Iron toxicity Monoamine oxidase inhibitor toxicity Multifocal atrial tachycardia Polysubstance overdose Septic shock Status epilepticus Theophylline toxicity Thyrotoxicosis Ventricular fibrillation Ventricular tachycardia Prognosis There are [ncbi.nlm.nih.gov]
Workup
Serum
- Hyponatremia
Caffeine toxicity can result in hypokalemia, hypocalcemia, hyponatremia, and hyperglycemia. It is also important to obtain serum myoglobin and creatine kinase levels to monitor for rhabdomyolysis. [ncbi.nlm.nih.gov]
Rhythm
- Premature Atrial Contractions
Symptoms include restlessness, anxiety, general depression, tachycardia, arrhythmias (premature atrial contractions), tremors, nausea, diuresis, and insomnia. [medical-dictionary.thefreedictionary.com]
Treatment
Mortality is very rare for patients who seek treatment. Those who do not seek treatment or the treatment is delayed may develop seizures, arrhythmias or even aspirate the vomitus. Over the past decade, less than 3 dozen deaths have been reported. [ncbi.nlm.nih.gov]
In one case, energy drink caffeinism, led to a severe brain hemorrhage and massive loss of brain matter.[18] Treatment[edit] Treatment of mild caffeine intoxication is directed toward symptom relief; severe intoxication may require peritoneal dialysis [en.wikipedia.org]
These examples may contain colloquial words based on your search. intoxication à la caféine intoxication par la caféine Disorder on the basis of caffeine intoxication Treatment of severe caffeine intoxication is generally supportive, providing treatment [context.reverso.net]
Treatment In Case Of Caffeine Overdose The treatment for a caffeine overdose should be getting it out of the body while controlling the symptoms. [modernheartandvascular.com]
A severe overdose, marked by difficulty breathing, irregular or rapid heartbeat, chest pains, or vomiting requires prompt medical treatment. [wikihow.com]
Prognosis
Serum caffeine levels can guide prognosis and therapy. [ncbi.nlm.nih.gov]
Etiology
[…] overuse or severe toxicity with an intentional overdose. [2] Lethal doses of caffeine have been reported at blood concentrations of 80 to 100 micrograms/ml which can be reached with ingestion of approximately 10 grams or greater. [3] [4] [5] [6] [7] Etiology [ncbi.nlm.nih.gov]
Epidemiology
It is recommended that the person reduces caffeine consumption gradually to avoid withdrawal as attempts to suddenly discontinue all caffeine consumption are frequently abandoned due to the severity of the withdrawal symptoms.[1][19] Epidemiology[edit [en.wikipedia.org]
Some examples include health food products, diet aids decongestants, bronchodilators, or stay-awake pills. [13] Epidemiology In 2016 there were 3702 caffeine related exposures reported to Poison Control Centers in the United States, with an equal ratio [ncbi.nlm.nih.gov]
Pathophysiology
"Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons". Physiological Reviews. 85 (1): 201–79. doi:10.1152/physrev.00004.2004. PMID 15618481. S2CID 11820734. ^ ^ "FDA Consumer Advice on Powdered Pure Caffeine". [en.wikipedia.org]
There have been several caffeine-related deaths reported in case studies. [12] Pathophysiology Due to caffeine’s ability to affect a variety of different receptors, the side effects of caffeine overdose can be profound. [ncbi.nlm.nih.gov]
Prevention
You may need to take activated charcoal, a common drug overdose remedy that often prevents caffeine from entering the gastrointestinal tract. [modernheartandvascular.com]
Seeking Outside Help Treating Mild Symptoms At Home Preventing a Reoccurrence Ask a Question Related Articles References Caffeine is a stimulant that keeps you awake and alert. [wikihow.com]
Signs and symptoms[edit] Primary symptoms of caffeine intoxication[3] In moderate doses, caffeine is used to reduce physical fatigue, to prevent drowsiness and sleep, and to maintain and restore mental alertness and wakefulness. [en.wikipedia.org]
Authors also indicated the blood levels of caffeine and highlighted that even high blood concentration of caffeine in infants can be successfully treated, thus preventing the death of the patient [ 23 ]. [ncbi.nlm.nih.gov]
Not only should non-invasive monitoring, like continuous cardiac monitoring, and fingerstick glucose level be rapidly obtained, but also intravenous access must be established. 9 11 12 To prevent systemic effects of the caffeine metabolism, activated [casereports.bmj.com]