We present a case of intentional caffeine poisoning in a 5-week-old infant and review treatment. This infant later suffered fatal physical abuse. [pediatrics.aappublications.org]

Case presentation A 32-year-old woman with no significant medical and family history presented to the local emergency department (ED) referring malaise, anxiety, dizziness and nausea. [casereports.bmj.com]

Indeed, many patients present at ages or with histories incompatible with “accidental” ingestion, others may even present with histories of recurrent illnesses suggesting previous undiagnosed poisonings. [ncbi.nlm.nih.gov]

• Fever

  There was no reported fever, vomiting, diarrhea, or respiratory symptoms. Initial examination revealed a well-developed, well-nourished 5-week-old infant. [pediatrics.aappublications.org]

  Symptoms like chest pain, syncope, palpitations or fever were denied. [casereports.bmj.com]

  Other substances that use these same pathways, such as alcohol or medications, can prolong the half-life of caffeine by approximately 72%. [9] [6] History and Physical Physical exam findings characteristic for caffeine toxicity include fever, tachycardia [ncbi.nlm.nih.gov]

• Fatigue

  The person could suffer from severe symptoms of caffeine withdrawal including headaches, fatigue, and difficulty concentrating. [en.wikipedia.org]

  Some side effects of excessive caffeine intake can include anxiety, insomnia, digestive issues, muscle breakdown, addiction, high blood pressure, rapid heart rate, fatigue, frequent urination, and urgency. [modernheartandvascular.com]

  Indeed, some disorders are typically linked to recreational and professional athletes who consume caffeine to face fatigue and intense workouts. An example is muscle dysmorphia. [ncbi.nlm.nih.gov]

• Anorexia

  Symptoms associated with high doses of caffeine include muscle twitching, rambling flow of thought and speech, tachycardia and cardiac arrhythmia, periods of inexhaustibility, and psychomotor agitation,[1] anorexia (loss of appetite). [en.wikipedia.org]

  This condition, also known as “reverse anorexia” or “Adonis complex”, is a subtype of body dysmorphic disorder generally affecting men, with its onset in adolescence or early adulthood, characterized by obsessiveness and compulsivity directed toward achieving [ncbi.nlm.nih.gov]

• Nausea

  Symptoms include restlessness, anxiety, general depression, tachycardia, arrhythmias (premature atrial contractions), tremors, nausea, diuresis, and insomnia. [medical-dictionary.thefreedictionary.com]

  Case presentation A 32-year-old woman with no significant medical and family history presented to the local emergency department (ED) referring malaise, anxiety, dizziness and nausea. [casereports.bmj.com]

  Most of the time, if individuals have severe signs of caffeine toxicity, it starts with nausea and vomiting. So that is somewhat protective because you get sick and throw up the caffeine before it gets too toxic. [modernheartandvascular.com]

• Loss of Appetite

  The symptoms of caffeine intoxication are comparable to the symptoms of overdoses of other stimulants.[3] In cases of much larger overdoses, mania, depression, lapses in judgment, disorientation, disinhibition, delusions, weight loss, loss of appetite [en.wikipedia.org]

• Palpitations

  We will discuss caffeine, how it can cause heart palpitations, and what you can do about it. Heart Palpitations Most of the time, you are probably unaware of your heartbeat or rhythm. [modernheartandvascular.com]

  These symptoms including nervousness, irritability, restlessness, insomnia, headaches, and palpitations after caffeine use.[4] Caffeinism usually occurs when consumption of caffeine reaches 1–1.5 grams (0.035–0.053 oz) per day.[5] For reference, a brewed [en.wikipedia.org]

  Symptoms like chest pain, syncope, palpitations or fever were denied. [casereports.bmj.com]

• Hypotension

  Caffeine can stimulate the release of catecholamines, especially noradrenaline, with beta 1 agonist activity resulting in tachycardia and beta 2 agonist activity resulting in peripheral vasodilation and hypotension. [14] [10] [4] [15] Caffeine also sensitizes [ncbi.nlm.nih.gov]

  To address hypotension, intravenous fluid therapy with isotonic fluid should be initiated. 12 Any patient with a haemodynamically unstable dysrhythmia should be treated by advanced cardiac life support protocols. 9 In several published case reports, a [casereports.bmj.com]

• Tinnitus

  And in toxic doses, caffeine directly releases calcium from intracellular stores, which also may increase the susceptibility for arrhythmias. 8 Symptoms of caffeine intoxication may include headache, fever, nausea, vomiting, tachycardia, dizziness, tinnitus [casereports.bmj.com]

• Agitation

  Reportedly he had been fine earlier in the day, but on the mother's return home, she noticed that he was agitated and irritable. The father attributed the change to a 1-year-old sibling having sat on the child's chest. [pediatrics.aappublications.org]

  After observation, the patient had an episode of presyncope followed by agitation and vomiting. [casereports.bmj.com]

  Symptoms associated with high doses of caffeine include muscle twitching, rambling flow of thought and speech, tachycardia and cardiac arrhythmia, periods of inexhaustibility, and psychomotor agitation,[1] anorexia (loss of appetite). [en.wikipedia.org]

  A neurologic exam may demonstrate altered mentation, agitation, delusional thought, hallucinations, seizures or even focal neurologic findings thought to be due to ischemia from vasoconstriction. [ncbi.nlm.nih.gov]

• Insomnia

  Symptoms include restlessness, anxiety, general depression, tachycardia, arrhythmias (premature atrial contractions), tremors, nausea, diuresis, and insomnia. [medical-dictionary.thefreedictionary.com]

  Low-dose symptoms include restlessness, nervousness, excitement, insomnia, flushed face, diuresis (increased urination), and gastrointestinal disturbance. [en.wikipedia.org]

  Some side effects of excessive caffeine intake can include anxiety, insomnia, digestive issues, muscle breakdown, addiction, high blood pressure, rapid heart rate, fatigue, frequent urination, and urgency. [modernheartandvascular.com]

  […] directly releases calcium from intracellular stores, which also may increase the susceptibility for arrhythmias. 8 Symptoms of caffeine intoxication may include headache, fever, nausea, vomiting, tachycardia, dizziness, tinnitus, anxiety, irritability, insomnia [casereports.bmj.com]

  Common features of caffeine intoxication, also known as “caffeinism” (i.e., a state of chronic toxicity from excessive caffeine consumption), include anxiety, agitation, restlessness, insomnia, gastrointestinal disturbances, tremors, psychomotor agitation [ncbi.nlm.nih.gov]

• Confusion

  If you're experiencing intense symptoms, like dizziness, confusion, an irregular heartbeat, or difficulty breathing, go to the ER right away. Do not try to drive yourself. Call 911. In rare cases, caffeine overdoses can be fatal. [wikihow.com]

Mortality is very rare for patients who seek treatment. Those who do not seek treatment or the treatment is delayed may develop seizures, arrhythmias or even aspirate the vomitus. Over the past decade, less than 3 dozen deaths have been reported. [ncbi.nlm.nih.gov]

In one case, energy drink caffeinism, led to a severe brain hemorrhage and massive loss of brain matter.[18] Treatment[edit] Treatment of mild caffeine intoxication is directed toward symptom relief; severe intoxication may require peritoneal dialysis [en.wikipedia.org]

These examples may contain colloquial words based on your search. intoxication à la caféine intoxication par la caféine Disorder on the basis of caffeine intoxication Treatment of severe caffeine intoxication is generally supportive, providing treatment [context.reverso.net]

Treatment In Case Of Caffeine Overdose The treatment for a caffeine overdose should be getting it out of the body while controlling the symptoms. [modernheartandvascular.com]

A severe overdose, marked by difficulty breathing, irregular or rapid heartbeat, chest pains, or vomiting requires prompt medical treatment. [wikihow.com]

Serum caffeine levels can guide prognosis and therapy. [ncbi.nlm.nih.gov]

[…] overuse or severe toxicity with an intentional overdose. [2] Lethal doses of caffeine have been reported at blood concentrations of 80 to 100 micrograms/ml which can be reached with ingestion of approximately 10 grams or greater. [3] [4] [5] [6] [7] Etiology [ncbi.nlm.nih.gov]

It is recommended that the person reduces caffeine consumption gradually to avoid withdrawal as attempts to suddenly discontinue all caffeine consumption are frequently abandoned due to the severity of the withdrawal symptoms.[1][19] Epidemiology[edit [en.wikipedia.org]

Some examples include health food products, diet aids decongestants, bronchodilators, or stay-awake pills. [13] Epidemiology In 2016 there were 3702 caffeine related exposures reported to Poison Control Centers in the United States, with an equal ratio [ncbi.nlm.nih.gov]

"Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons". Physiological Reviews. 85 (1): 201–79. doi:10.1152/physrev.00004.2004. PMID 15618481. S2CID 11820734. ^ ^ "FDA Consumer Advice on Powdered Pure Caffeine". [en.wikipedia.org]

There have been several caffeine-related deaths reported in case studies. [12] Pathophysiology Due to caffeine’s ability to affect a variety of different receptors, the side effects of caffeine overdose can be profound. [ncbi.nlm.nih.gov]

You may need to take activated charcoal, a common drug overdose remedy that often prevents caffeine from entering the gastrointestinal tract. [modernheartandvascular.com]

Seeking Outside Help Treating Mild Symptoms At Home Preventing a Reoccurrence Ask a Question Related Articles References Caffeine is a stimulant that keeps you awake and alert. [wikihow.com]

Signs and symptoms[edit] Primary symptoms of caffeine intoxication[3] In moderate doses, caffeine is used to reduce physical fatigue, to prevent drowsiness and sleep, and to maintain and restore mental alertness and wakefulness. [en.wikipedia.org]

Authors also indicated the blood levels of caffeine and highlighted that even high blood concentration of caffeine in infants can be successfully treated, thus preventing the death of the patient [ 23 ]. [ncbi.nlm.nih.gov]

Not only should non-invasive monitoring, like continuous cardiac monitoring, and fingerstick glucose level be rapidly obtained, but also intravenous access must be established. 9 11 12 To prevent systemic effects of the caffeine metabolism, activated [casereports.bmj.com]