Dermatomyositis sine myositis presenting with calcinosis universalis SIR, Dermatomyositis can initially present without muscle involvement. [deepdyve.com]

It is classified into four types according to etiology, namely as dystrophic if calcium and phosphorus levels are normal and tissue damage is present, as idiopathic if calcium and phosphorus levels are normal and no tissue damage is present, or as metastatic [karger.com]

Lupus erythematosus: uncommon presentations. Clin Dermatol 2005;23:470-479. 6. Wollina U, Hein G. Lupus erythematosus: uncommon presentations. Clin Dermatol 2005;23:470-479. Fig. 4. [sajr.org.za]

The purpose of this paper is to present a case of a rare condition and a treatment which yielded satisfactory results. The case was observed at frequent intervals for a period of four years. [jamanetwork.com]

Abstract A short discussion of calcification in soft tissues with special reference to calcinosis circumscripta and calcinosis universalis is presented. [journals.co.za]

• Weight Gain

  Concurrent with resolution of the calcinosis was an improved sense of well-being and a 16.5-kg weight gain. Range of motion improved in all joints, except internal rotation of his hips. [academic.oup.com]

• Respiratory Distress

  The patient denied any history of fever, joint pains, weakness or pain in the muscles around shoulder and hip, pain or bluish discolouration of extremities, chest pain or respiratory distress. There was no family history of a similar illness. [ijdvl.com]

• Pleural Effusion

  Her chest radiograph showed a right pleural effusion with cardiomegaly (Fig. 1), and radiographs of the hips and hands demonstrated widespread calcifications in the soft tissue and no evidence of arthropathy (Figs 2a and b). [sajr.org.za]

• Gagging

  Akkari; Gilberto Waisberg; Clóris Kessler; Tabata de Alcantara; Patrícia L Delai Related Documents : 8206076 - Vulvar intraepithelial neoplasia of low grade: a challenging diagnosis. 8367356 - Acute urinary retention in children. 9533356 - Psychogenic gagging [biomedsearch.com]

• Cardiomegaly

  Her chest radiograph showed a right pleural effusion with cardiomegaly (Fig. 1), and radiographs of the hips and hands demonstrated widespread calcifications in the soft tissue and no evidence of arthropathy (Figs 2a and b). [sajr.org.za]

• Oral Ulcers

  A few had ulcerated. There was no facial erythema, oral ulceration, finger tip ulceration or scars, nail fold capillaries, sclerodactyly and telangiectasia. Raynaud's phenomena could not be elicited. [ijdvl.com]

• Myopathy

  She denied having had any previous complaints compatible with myopathy. [scielo.br]

  Inflammatory myopathies: Part 1. Ann Neurol. 1985;17:215-27. [ pubmed/open access ] [ crossref ] 5. Mastaglia FL, Ojeda VJ. Inflammatory myopathies: Part 2. Ann Neurol. 1985;17:317-23. [ pubmed/open access ] [ crossref ] 6. Miller FW. [jped.com.br]

  Chester V Oddis, Idiopathic inflammatory myopathy: management and prognosis, Rheumatic Disease Clinics of North America, 28, 4, (979), (2002). Ann M. [doi.org]

  Introduction Juvenile dermatomyositis (JDM) is a rare disease but it is the most common inflammatory myopathy in children. It is an autoimmune vasculopathy which primarily affects skin and proximal striated muscles. [scirp.org]

  At age 10 yr, muscle biopsy showed an inflammatory myopathy. Serum creatine phosphokinase (CPK) level was approximately 12,600 U/L (normal, 30–220 U/L). [academic.oup.com]

• Morning Stiffness

  Her current complaints were polyarthritis involving the small joints of her hands,elbows and knees with associated morning stiffness. On examination, she appeared chronically affected. [sajr.org.za]

• Shuffling Gait

  He walked with a shuffling gait secondary to limited range of motion at his hips and knees. Figure 1. Patient, age 18 yr, before probenecid therapy showing arm contractures caused by ectopic calcifications. Figure 1. [academic.oup.com]

• Soft Tissue Calcification

  No cause could be found for the soft tissue calcification. The co-existence of the two diseases is probably incidental. [ncbi.nlm.nih.gov]

  Soft tissue calcifications may be easily demonstrated on plain radiographs, but CT scan is more effective in demonstrating the location and extent of calcifications. [sajr.org.za]

  Abstract Soft tissue calcification is sometimes found in scleroderma and dermatomyositis, however, to our knowledge, only 29 cases of systemic lupus erythematosus (SLE) were reported to have soft tissue calcification. [jstage.jst.go.jp]

  Soft tissue calcification, with special reference to its occurrence in “collagen disease”. Ann. int. Med. 36, 1050. PubMed Google Scholar Copyright information © Dr. K C Chaudhuri Foundation 1968 Authors and Affiliations A. S. Sethi 1 S. C. [link.springer.com]

• Right Pleural Effusion

  Her chest radiograph showed a right pleural effusion with cardiomegaly (Fig. 1), and radiographs of the hips and hands demonstrated widespread calcifications in the soft tissue and no evidence of arthropathy (Figs 2a and b). [sajr.org.za]

• TmP/GFR Decreased

  Intact PTH levels became measurable in the normal range, and urinary tubular reabsorption of phosphate (TRP) and TmP/GFR decreased. [academic.oup.com]

• Staphylococcus Aureus

  A 5×2.5 cm left gluteus abscess was identified over MRI and Methicillin-resistant Staphylococcus aureus was isolated, and treated with vancomycin and surgical drainage. [casereports.bmj.com]

  A 5×2.5 cm left gluteus abscess was identified over MRI and Methicillin-resistant Staphylococcus aureus was isolated, and treated with vancomycin and surgical drainage. [docksci.com]

• Pleural Effusion

  Her chest radiograph showed a right pleural effusion with cardiomegaly (Fig. 1), and radiographs of the hips and hands demonstrated widespread calcifications in the soft tissue and no evidence of arthropathy (Figs 2a and b). [sajr.org.za]

The treatment and possible mechanisms of this complication are discussed. [pennstate.pure.elsevier.com]

Successful treatment of calciphylaxis with intravenous sodium thiosulfate. Am J Kidney Dis 2004;43:1104–8. Google Scholar | Crossref | Medline | ISI 21. Ambler, GR, Chaitow, J, Rogers, M. [journals.sagepub.com]

Medical and surgical treatment are options to cure calcinosis cutis. Medical treatment using bisphosphonate. A better understanding of the process of calcinosis cutis will lead to therapies to improve patient morbidity. [ijpeonline.biomedcentral.com]

Different treatments have been used in an attempt to clear calcinosis lesions and prevent its recurrence but none has been clearly effective. [ncbi.nlm.nih.gov]

Treatment and prognosis No established therapy is recognized, but calcium chelates (EDTA) bisphosphonates, and steroids have been used with little consistent benefit. [radiopaedia.org]

The prognosis however is generally poor. References 1. Black MM, Gawkrodyer DJ, Seymour CA, Weismann K. Metabolic and nutritional disorders. In: Champion RH, Burton JL, Ebling FJG, eds. Oxford: Blackwell Scientific Publication, 1993:2295-381. 2. [ijdvl.com]

Chester V Oddis, Idiopathic inflammatory myopathy: management and prognosis, Rheumatic Disease Clinics of North America, 28, 4, (979), (2002). Ann M. [doi.org]

In general, dysphagia portends a poor prognosis. Vascular involvement in DM usually presents as small vessel vasculitis. 1,8 Treatment Treatment of DM. DM usually responds well to treatment with systemic steroids. [woundsresearch.com]

Abstract Calcinosis universalis is a rare and interesting condition of unknown etiology characterized by deposits of calcium in the skin and subcutaneous tissues. The diagnosis is easily made roentgenographically. [pubs.rsna.org]

Since then, the syndrome has been the subject of a great deal of discussion and controversy as to the etiology, the pathology and the therapy concerned. [jamanetwork.com]

It is classified into 4 major types according to etiology: dystrophic, metastatic, iatrogenic, and idiopathic. [ajnr.org]

The etiology is not known. [nejm.org]

2:1, and which has an incidence of 3.2/1,000,000 children and adolescents/year in the United States. 7 Despite its rarity, it is the fourth most frequent disease at tertiary pediatric rheumatology services, and there are no Brazilian studies of its epidemiology [jped.com.br]

Little is known about the pathophysiology of calcinosis and there is no universally recognized treatment. Intravenous pamidronate significantly reduced the calcinosis. Early recognition and aggressive treatment of calcinosis is highlighted. [content.iospress.com]

[…] scleroderma CREST syndrome, lupus erythematosus, overlap syndromes or dermatomyosistis. 1 Likewise the rarely described calcinosis cutis universalis is mostly associated with collagenoses but even other diseases like graft-versus-host can be rare causes. 2 Pathophysiologically [academic.oup.com]

[…] subcutaneous fatty tissue septa, intramuscular septa, muscle fasciae, tenosinovitis or articular sinovitis. [4] Inflammatory stage of morphea reveal infiltration in the sucutaneous tissue with increase signal intensity on STIR sequences. [5] Depending on the pathophysiologic [mjdrdypu.org]

Different treatments have been used in an attempt to clear calcinosis lesions and prevent its recurrence but none has been clearly effective. [ncbi.nlm.nih.gov]

Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse [books.google.com]

Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]

Although the existing lesions showed slow improvement, systemic pamidronate therapy was effective in preventing the occurrence of new lesions. Surgical excision proved to be an effective and successful treatment. [karger.com]

Early diagnosis of the disease and effective treatment are essential to prevent calcinosis universalis from complicating this disease in children. [jle.com]