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Calcium Gluconate


Presentation

  • It was also noted that calcium gluconate was more effective in patients who presented 3 hours of more after they were bitten. Antivenom may be necessary in those who present with symptoms in less than 3 hours.[ncbi.nlm.nih.gov]
Soft Tissue Swelling
  • Abstract Calcium gluconate is irritating to soft tissues and can produce tissue necrosis and slough; Radiographs of the part following extravasation initially show only soft tissue swelling.[ncbi.nlm.nih.gov]
Acute Intermittent Porphyria
  • We report a 26-year-old woman who was hospitalized for exacerbation of acute intermittent porphyria. She had a history of hypertension and chronic renal failure.[ncbi.nlm.nih.gov]
Cyanosis
  • -Carefully monitor infants of hypocalcemic mothers for abnormal calcium levels; signs include neuromuscular irritability, apnea, cyanosis, and cardiac arrhythmias.[drugs.com]
Subcutaneous Nodule
  • The lesions appeared at the intravenous sites as firm subcutaneous nodules or areas of areas of inflammation with central softening and fluctuation.[ncbi.nlm.nih.gov]
Papule
  • The 2 most frequent symptoms were the appearance of erythema (65%) and swelling/edema (48%) followed by the appearance of skin necrosis (47%), indurated skin (33%), and yellow-white plaques or papules (33%).[ncbi.nlm.nih.gov]
Polyradiculoneuropathy
  • The most common indications were myasthenia gravis (37%), acute inflammatory demyelinating polyradiculoneuropathy (31%), and chronic inflammatory demyelinating polyneuropathy (13%).[ncbi.nlm.nih.gov]
Quadriplegia
  • With the development of such clinical symptoms of severe hypokalemia as quadriplegia, he was confirmed to have severe hypokalemia through a biochemical test before dying of arrhythmia.[ncbi.nlm.nih.gov]

Workup

Hypochlorhydria
  • INTRODUCTION: Gastrectomy and hypochlorhydria due to long-term proton pump inhibitor therapy are associated with increased fracture risk because of intestinal calcium malabsorption.[ncbi.nlm.nih.gov]
  • In patients with achlorhydria or hypochlorhydria, calcium absorption, especially with the carbonate salt, may be reduced. Volume of distribution Not available Protein binding Moderate, approximately 45% in plasma.[drugbank.ca]

Treatment

  • Citrate reactions occurred in 35.6% of Group A and 29.4% of Group B treatments (P 0.3), but in only 8.6% of Group C treatments (P 0.0001).[ncbi.nlm.nih.gov]
  • The other lesion for each animal received no treatment; in this experimental design, each rat is its own control for assessment of treatment efficacy.[doi.org]

Epidemiology

  • The aim of this study is to present a number of cases of calcium gluconate extravasation, which have occurred in our hospital, and to carry out a review of those clinical cases published in the literature to obtain relevant epidemiological data.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • And also it presented pathophysiologic mechanism underlying severe hypokalemia as well as suggestions for clinical practice regarding combination use of dexamethasone and calcium gluconate.[ncbi.nlm.nih.gov]

Prevention

  • Abstract We have examined the effectiveness of intravenous calcium gluconate infusion in the prevention of citrate reactions during therapeutic plasma exchange.[ncbi.nlm.nih.gov]
  • Supplementation may be done to treat or prevent osteoporosis or rickets.[en.wikipedia.org]

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