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Campylobacter Pylori


Presentation

  • H.pylori is probably the most common cause of chronic bacterial infection of humans, present in almost half of the world population.[uniprot.org]
  • HopE is a 31 kD porin protein which is part of a family of 32 outer membrane proteins present in Helicobacter pylori bacteria. HopE is highly conserved in Helicobacter pylori strains, but not among other strains of the Helicobacter genus.[shop.leicabiosystems.com]
  • This international workshop will feature presentations by international and local experts reporting their most recent scientific updates and will provide the opportunity to meet, listen to and interact with world-class experts in the areas of scientific[ifst.org]
  • These studies, in addition to being few in number (only 2 groups of investigators have presented results) are contradictory.[revespcardiol.org]
  • Sarari et al. showed that vitamin B12 deficiency was present in 67.4% (29/43) of the patients with H. pylori infection [ 44 ].[jbiomedsci.biomedcentral.com]
Pathologist
  • Australian pathologist and Nobel Laureate, Robin Warren, needs no introduction.[chro2019.com]
Pneumonia
  • Rabbit model for Chlamydia pneumoniae infection.. J Clin Microbiol, 35 (1997), pp. 48-52 [35] Mendall M, Patel P, Asante M, Ballam L, Morris J, Sttracham D, et al..[revespcardiol.org]
  • Role of chlamydia pneumoniae, helicobacter pylori and cytomegalovirus in coronary artery disease. Pak J Pharm Sci. 2011;24(2):95–101. PubMed Google Scholar Figura N, Palazzuoli A, Vaira D, et al.[jbiomedsci.biomedcentral.com]
Dyspepsia
  • Altay et al [33] reported a 26.6% prevalence rate of H. pylori infection among chronic ambulatory peritoneal dialysis (CAPD) patients complaining of dyspepsia.[sjkdt.org]
Melena
  • Kids who have peptic ulcer disease can have ulcers that bleed, causing hematemesis (bloody vomit or vomit that looks like coffee grounds) or melena (stool that's black, bloody, or looks like tar).[kidshealth.org]
Heart Disease
  • Serological evidence of an association of a novel Chlamydia, TWAR; with chronic coronary heart disease and acute myocardial infarction.. Lancet, 8 (1988), pp. 983-5 [7] Ellis R.. Infection and coronary heart disease..[revespcardiol.org]
  • CagA-positive helicobacter pylori strains enhanced coronary atherosclerosis by increasing serum OxLDL and HsCRP in patients with coronary heart disease. Dig Dis Sci. 2011;56(1):109–14.[jbiomedsci.biomedcentral.com]

Workup

Helicobacter Pylori
  • See Helicobacter pylori Diagnostic Algorithm in Special Instructions.[mayocliniclabs.com]
  • The role of helicobacter pylori infection in hematological disorders. Eur J Intern Med. 2013;24(8):685–90. View Article PubMed Google Scholar Buzas GM. Metabolic consequences of helicobacter pylori infection and eradication.[jbiomedsci.biomedcentral.com]
  • , entre éstos Helicobacter pylori, agente etiopatogénico de enfermedad gastroduodenal.[revespcardiol.org]
  • Prevalence of Helicobacter pylori antibodies in CAPD patients. Nephron 1997;75(3):358-9. 27. Schoonjans R, Van VB, Vandamme W, et al. Dyspepsia and gastro paresis in chronic renal failure: the role of Helicobacter pylori.[sjkdt.org]
  • New Oral Vaccine Protects Children From Helicobacter Pylori Infection. Reuters Health Information. Available at . July 16, 2015; Accessed: May 2, 2016. Ruggiero P. Helicobacter pylori infection: what's new.[emedicine.medscape.com]
Chlamydia
  • […] pneumoniae, 5 Chlamydia TWAR, 6 and cytomegalovirus 7 such as, for example, the finding on PCR or immunofluoresence of Chlamydia pneumoniae and Chlamydia TWAR in atheromatous plaques by PCR, immunocytochemistry, and electron microscope. 5 A relationship[revespcardiol.org]
  • Role of chlamydia pneumoniae, helicobacter pylori and cytomegalovirus in coronary artery disease. Pak J Pharm Sci. 2011;24(2):95–101. PubMed Google Scholar Figura N, Palazzuoli A, Vaira D, et al.[jbiomedsci.biomedcentral.com]
Gram-Positive Bacteria
  • Figure 4: A general model for peptide-mediated quorum sensing in Gram-positive bacteria. In Gram-positive bacteria, a peptide signal precursor locus is translated into a precursor protein (black and ...[annualreviews.org]
Pseudomonas
  • Roots of 17-day-old radish plants from which the seeds were inoculated with (a) auxin-producing Pseudomonas corrugata SPB2184 suspended in 1% methylcel...[annualreviews.org]
Polyps
  • […] pylori) is a gramnegative spiral flagellate bacillus that resides usually in the gastric mucosa and can cause chronic active gastritis and peptic ulcer disease. [1] In addition, chronic H. pylori infection has close associations with gastric hyperplastic polyps[sjkdt.org]

Treatment

  • Treatment Doctors treat H. pylori infections using antibiotics. Because a single antibiotic may not kill the bacteria, your child will normally be given a combination of antibiotics.[kidshealth.org]
  • Antimicrobial sensitivity and treatment of Helicobacter pylon infections. Harefuah 1994;126:126-8. [ PUBMED ] 12. Malanoski GJ, Eliopoulos GM, Ferraro MJ, Moellering RC.[saudijgastro.com]
  • Role of Helicobacterpylori in gastro-duodenal mucosal lesions in patients with end stage renal disease under dialysis treatments. Nippon Jinzo Gakkai Shi 1995;37:503. [ PUBMED ] 71. Tokushima H, Tamura H, Murakawa M, et al.[sjkdt.org]
  • Lactobacillus reuteri therapy to reduce side-effects during anti-Helicobacter pylori treatment in children: a randomized placebo controlled trial. Aliment Pharmacol Ther. 2006 Nov 15. 24(10):1461-8. [Medline].[emedicine.medscape.com]
  • Pylori treatment in patients with immune thrombocytopenic purpura with and without H. Pylori infection: a systematic review. Haematologica. 2009;94(6):850–6. View Article PubMed PubMed Central Google Scholar Kuwana M.[jbiomedsci.biomedcentral.com]

Prognosis

  • […] of H. pylori and markers of inflammatory processes There is growing evidence that inflammation plays an etiopathogenic role in atherosclerosis and that some markers of inflammation are associated with a greater risk of coronary cardiopathy or a worse prognosis[revespcardiol.org]

Etiology

  • H. pylori, give its widespread distribution in the world population and the high incidence of gastro duodenal disease, is 1 of the most important microorganisms associated with illness that were previously considered to have a non-infectious etiology.[revespcardiol.org]

Epidemiology

  • […] species. - Outbreaks/Epidemiology and public health.[ifst.org]
  • TABLE 32–1 Features of Vibrio, Campylobacter, and Helicobacter a View Table Favorite Table Download (.pdf) TABLE 32–1 Features of Vibrio, Campylobacter, and Helicobacter a BACTERIOLOGY PATHOGENESIS ORGANISM GROWTH UREASE EPIDEMIOLOGY ADHERENCE TOXINS[accessmedicine.mhmedical.com]
  • Vibrio cholerae serogroups non-O1/non-O139 Cholera-like diarrhea; mild diarrhea; rarely, extraintestinal infection Vibrio parahaemolyticus Gastroenteritis, wound infections, septicemia Vibrio vulnificus Gastroenteritis, wound infections, septicemia The epidemiology[accessmedicine.mhmedical.com]
  • Estimates indicate that approximately 60% of the world population is colonized with this agent. [15] However; the epidemiological data concerning H. pylori infection in ESRD patients are controversial.[sjkdt.org]
  • Epidemiology Frequency United States Overall, approximately one-third of the population is infected with H pylori, increasing with age. See Age.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology H pylori organisms are spiral-shaped gram-negative bacteria that are highly motile because of multiple unipolar flagella. They are microaerophilic and potent producers of the enzyme urease.[emedicine.medscape.com]

Prevention

  • Prevention Right now, there's no vaccine against H. pylori. And because transmission isn't clearly understood, prevention guidelines aren't available. However, it's always important to make sure you and your family: Wash your hands thoroughly.[kidshealth.org]
  • Catalase helps H pylori survive in the host by preventing the formation of reactive oxygen metabolites from hydrogen peroxide. The LPS outer membrane of H pylori is a less potent inducer of the host complement cascade.[emedicine.medscape.com]

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