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Candida Albicans Vaginitis

Presentation

A thin/watery gray-white discharge is present A fouls smell is present and often described as an Amine Odor or Fishy Smell. This smell is intensified after unprotected intercourse or when KOH is added (AKA Positive Whiff Test). [stomponstep1.com]

At present, no information is available regarding the biologic mechanism of fluconazole resistance in the vaginal isolates and these studies are ongoing. [journals.lww.com]

Yeast is believed to be present in the vagina of 20%-50% of healthy women. [emedicinehealth.com]

At least one swab identified to species level is an essential part of the diagnostic workup of any woman presenting with chronic or persistent vaginitis. Usually, but not always, the yeast is present in large amounts and is visible on microscopy. [sti.bmj.com]

Skin

  • Urticaria

    […] pemphigoid, herpes gestationalis and dermatitis herpetiformis Gram negative bacilli Donovanosis Chancroid Granulomatous disorders Including Crohn's disease and sarcoidosis Spirochaetes Syphilis Vasculopathic disorders Including Behcet's disease and urticaria [nps.org.au]

Neurologic

  • Burning Sensation

    A burning sensation and pain during intercourse or urination are also characteristic symptoms of a yeast vaginitis. Unlike the discharge of bacterial vaginosis, the discharge of a yeast infection is typically odorless. [emedicinehealth.com]

    She describes the discharge as watery and yellow, and she has had an associated burning sensation on urination. She otherwise feels well and has no complaints. [medbullets.com]

    Symptoms Yeast infection symptoms can range from mild to moderate, and include: Itching and irritation in the vagina and vulva A burning sensation, especially during intercourse or while urinating Redness and swelling of the vulva Vaginal pain and soreness [mayoclinic.org]

    However, it can be uncomfortable and you may experience a burning sensation during or after sex. Use plenty of lubricant to protect your skin. Thrush is not an STI, but male partners can sometimes get redness and irritation after sex. [betterhealth.vic.gov.au]

    Vaginitis is characterized by symptoms like extreme itchiness, vaginal irritation, and discharge or burning sensation during intercourse or urination. [turmericforhealth.com]

  • Confusion

    Note that this finding can be easily confused with Cervicitis (Gon/Chlyamdia). [stomponstep1.com]

    […] include: immunosuppression certain medications such as antibiotics, immunosuppressants, or corticosteroids a recent surgical procedure Symptoms Symptoms of fungal meningitis include: headache stiff neck fever nausea and vomiting sensitivity to light confusion [medicalnewstoday.com]

Urogenital

  • Vaginal Discharge

    Vaginitis Etiology Clinical Presentation Bacterial vaginosis Gardnerella vaginalis Symptoms malodorous ( "fishy" odor) vaginal discharge nonpainful Physical exam off-white or gray and thin vaginal discharge normal vulva Vulvovaginal candidiasis Candida [medbullets.com]

    Your doctor may take a sample of the vaginal discharge to be examined in a laboratory under a microscope. Your doctor can confirm that you have Trichomonas vaginitis by examining your vaginal discharge under a microscope. [drugs.com]

    Other names used for vulvovaginal candidiasis are 'vaginal thrush’, ‘monilia’, and ' vulvovaginal candidosis'. What causes vaginal discharge ? Vaginal discharge is a normal process which keeps the mucosal lining of the vagina moist. [dermnetnz.org]

    Symptoms of Yeast Infection and Bacterial Vaginosis Like bacterial vaginosis, yeast infection may result in a vaginal discharge. [emedicinehealth.com]

    Prior to treatment, most of the women complained about vaginal itching and discharge, and had symptoms such as vaginal/vulval erythema and cottage cheese-like discharge. [smj.org.sg]

  • Dyspareunia

    Inflammation leads to burning, itching, erythema, dysuria and dyspareunia. Many leukocytes are seen on microscopic examination Patchy Erythema on cervix is referred to as Strawberry Petechiae. [stomponstep1.com]

    Use of a broad-spectrum antibiotic or corticosteroids Pregnancy Constrictive nonporous undergarments Immunocompromise Symptoms and Signs of Candidal Vaginitis Vaginal vulvar pruritus, burning, or irritation (which may be worse during intercourse) and dyspareunia [msdmanuals.com]

    Symptoms and Signs Vaginal vulvar pruritus, burning, or irritation (which may be worse during intercourse) and dyspareunia are common, as is a thick, white, cottage cheese–like vaginal discharge that adheres to the vaginal walls. [merckmanuals.com]

    Physical exam thick, white, odorless, and curd-like vaginal discharge vulvar erythema and edema Trichomoniasis Trichomonas vaginalis Symptoms malodo rous greenish discharge burning dyspareunia and dysuria postcoital bleeding Physical exam malodorous [medbullets.com]

    And in the absence of other infectious etiology. [2] The most common clinical manifestations of VVC are pruritus, hyperemia, vaginal discomfort and leucorrhea, burning, soreness, dyspareunia and vaginal or vulvar erythema, which may cause a problem in [ijpmonline.org]

  • Dysuria

    Inflammation leads to burning, itching, erythema, dysuria and dyspareunia. Many leukocytes are seen on microscopic examination Patchy Erythema on cervix is referred to as Strawberry Petechiae. [stomponstep1.com]

    […] especially under foreskin, may or may not be itchy White ‘curd like’ vaginal discharge although discharge can appear normal Swelling of foreskin if severe Genital/vulval itch, discomfort Fissures Superficial erosions Superficial dysparuenia External dysuria [sti.guidelines.org.au]

    Typical symptoms of VVC include pruritus, vaginal soreness, dyspareunia, external dysuria, and abnormal vaginal discharge. None of these symptoms is specific for VVC. [cdc.gov]

    Vulvovaginal candidiasis can be difficult to diagnose because characteristic signs and symptoms (thick, white discharge, dysuria, vulvovaginal pruritus and swelling) are not specific for the infection. [aafp.org]

  • Vaginal Odor

    Symptoms Bacterial vaginosis — Bacterial vaginosis causes an abnormal grayish-white vaginal discharge with a foul-smelling vaginal odor. [drugs.com]

    Vaginal douches can disrupt the balance of normal vaginal organisms and irritate vaginal tissues. Symptoms Normal vaginal fluid is white and odorless. Patients with vaginitis may develop abnormal vaginal discharge, irritation, itching, and odor. [innerbody.com]

    When to see a doctor See your doctor if you develop unusual vaginal discomfort, especially if: You have a particularly unpleasant vaginal odor, discharge or itching. You've never had a vaginal infection. [mayoclinic.org]

    Vaginitis Etiology Clinical Presentation Bacterial vaginosis Gardnerella vaginalis Symptoms malodorous ( "fishy" odor) vaginal discharge nonpainful Physical exam off-white or gray and thin vaginal discharge normal vulva Vulvovaginal candidiasis Candida [medbullets.com]

    […] discharge to a thick, white, chunky discharge (like cottage cheese) May have an unusual or unpleasant vaginal odor If you have these vaginal yeast infection symptoms, then it is likely that you have a vaginal yeast infection. [candida-albicans-cure.com]

  • Salpingitis

    Genital tract infections: Vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. In: Comprehensive Gynecology. 7th ed. Philadelphia, Pa.: Elsevier; 2017. https://www.clinicalkey.com. Accessed Aug. 26, 2018. Cohen J, et al., eds. [mayoclinic.org]

    Infections of the Lower and Upper Genital tracts: Vulva, Vagina, Cervix, Toxic Shock Syndrome, Endometritis, and Salpingitis. In: Lentz GM, Lobo RA, Gershenson DM, Katz VL, eds. Comprehensive Gynecology, 6e. Philadelphia, PA: Elsevier Mosby; 2012. [innerbody.com]

    Genital tract infections: vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 23. Habif TP. [medlineplus.gov]

    […] serious complications, such as erosion and/or ulceration of the cervix, infertility, ectopic pregnancy, cancer, perinatal morbidity, HIV transmission, related pathologies with obstetric infections, abortions, pelvic inflammatory disease, endometritis and salpingitis [imedpub.com]

Workup

At least one swab identified to species level is an essential part of the diagnostic workup of any woman presenting with chronic or persistent vaginitis. Usually, but not always, the yeast is present in large amounts and is visible on microscopy. [sti.bmj.com]

Following laboratory workup, 71 specimens were positive for genus Candida (30.6%). Further speciation showed 32.4% as Candida albicans, 45.07% Candida parapsilosis and 22.53% of Candida glabrata. [ijpmonline.org]

[…] treatments for vaginitis (boric acid, tea tree oil, live acidophilus, garlic) have not been well studied but may have some efficacy. [10, 11, 12] If the patient shows no improvement, despite symptomatic or over-the-counter treatment, refer her for further workup [emedicine.medscape.com]

Serum

  • Cytolytic Vaginosis

    According to the microbiology results, 50.6%, 25.6%, 17.4%, 5.3%, and 0.3% of the cases had cytolytic vaginosis, Gardnerella vaginalis, Candida vaginitis, trichomoniasis vaginosis, and gonorrhea, respectively (6). [jmrh.mums.ac.ir]

Microbiology

  • Mycoplasma Hominis

    Bacterial vaginosis is caused by proliferation of Gardnerella vaginalis, Mycoplasma hominis, and anaerobes. [aafp.org]

    In bacterial vaginosis, normal Lactobacillus bacteria are replaced by other bacteria, including Prevotella, Mobiluncus, G. vaginalis, and Mycoplasma hominis. The exact reason for this change is unknown. [drugs.com]

    Mobiluncus spp, and Mycoplasma hominis ( Figures 1 and 2 ) Figure 1 and 2. [imedpub.com]

Treatment

[…] two groups, suggesting that short-term treatment is most efficacious and can be expected to work better since patient compliance is primarily a function of duration of treatment. [pubmed.ncbi.nlm.nih.gov]

[…] after the treatment (P ˂ 0.001). [archcid.portal.tools]

Results: 85% of patients favourably responded to treatment, 10% remained asymptomatic for a period of less than one year and 5% of patients did not respond to treatment. [xn--revistaespaoladeozonoterapia-7xc.es]

Therefore, Zira capsule is suggested for the treatment of Candida albicans Vaginitis. [biomedpharmajournal.org]

Prognosis

What Is the Prognosis? Once treatment starts, most candidiasis infections get better within about 2 weeks. Recurrences are fairly common. Long-lasting thrush is sometimes related to pacifiers. [healthychildren.org]

Prognosis Medications cure up to 90% of vaginal infections. If you do not improve with the first treatment, your doctor usually can cure your infection with a longer course of medication, or a different medication. [drugs.com]

[…] pathogenesis disruption of this acidic environment results in vaginitis disruptive causes include menstruation sexual activity pregnancy foreign bodies sexually transmitted disease hygienic products antibiotics hypoestrogenic states ( e.g., menopause) Prognosis [medbullets.com]

Complications and prognosis Cure rate is 80% for uncomplicated cases [ 1 ]. Depression and psychosexual problems can occur in women who suffer recurrent episodes. [patient.info]

Cases of systemic candidiasis that are diagnosed quickly and treated effectively have the best prognosis, especially if the infection can be stopped before it spreads to major organs. [health24.com]

Etiology

Frequency and etiology of vulvovaginal candidiasis in women reffered to gynaecological center in Babol, Iran. Int J Fertil Steril 2009;3:74-7. 11. Ahmad A, Khan AU. [ijpmonline.org]

While many theories have been proposed, the etiology of this condition remains unknown. [emedicine.medscape.com]

Clinical study of Candida vaginitis in Ahvaz, Iran and susceptibility of agents to topical antifungal Ali Zarei Mahmoudabadi 1, Mahin Najafyan 2, Maryam Alidadi 3 Abstract Objective : To evaluate etiological agents of vaginal candidiasis in Ahvaz, Iran [pjms.com.pk]

Epidemiology

Any further epidemiologic claims would be distorted by the accrual bias of referred cases. [journals.lww.com]

In all microbiology laboratories so that the epidemiology, emergence and spread of non-albicans Candida could be revealed. [ijpmonline.org]

An epidemiological survey of vulvovaginal candidiasis in Italy. Eur JObstet Gynecol Reprod Biol. 2003 Sep 10;110(1):66-72. [ Links ] 16. VermitskyJP, SelfMJ, ChadwickSG, TramaJP, AdelsonME, MordechaiE, et al. [scielo.iics.una.py]

Pathophysiology

[…] by an alkaline vaginal discharge may lead to chronic irritation and inflammation Other - Some authors have associated vulvar vestibulitis with a history of sexual abuse, elective abortions, severe marital conflicts, depression, and anxiety Neurologic pathophysiology [emedicine.medscape.com]

Pathophysiology, causative organisms of bacterial vaginosis can cause diseases of the genital tract by releasing high as sialidases and mucinases enzymes that alter the mucosal barrier, decrease defense mechanisms of the cervix and vagina, increase the [imedpub.com]

Prevention

Protocol for a randomised controlled trial of treatment of asymptomatic candidiasis for the prevention of preterm birth [ACTRN12610000607077]. Roberts CL, Morris JM, Rickard KR, Giles WB, Simpson JM, Kotsiou G, Bowen JR. Roberts CL, et al. [pubmed.ncbi.nlm.nih.gov]

Prevention Because Trichomonas vaginitis is a STD that can be transmitted during sexual activity, you can help to prevent infection by: Not having sex Having sex with only one uninfected partner Consistently using male latex condoms during sexual intercourse [drugs.com]

Screening for bacterial vaginosis in pregnancy to prevent preterm delivery: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2008;148(3):214-219. Nygren P, Fu R, Freeman M, et al; U.S. Preventive Services Task Force. [aetna.com]

Centers for Disease Control and Prevention. Candida Infection of the Skin. MedlinePlus. Definition of Invasive Candidiasis. Centers for Disease Control and Prevention. Patient Education: Vaginal Yeast Infection (Beyond the Basics). UpToDate. [everydayhealth.com]

Women who are at high risk of a yeast infection may need to take an antifungal drug by mouth to help prevent yeast infections. [merckmanuals.com]

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