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Candidiasis

Candidiases


Presentation

  • We present a 16-year-old boy with global developmental delay who presented with this condition associated with candidal infection.[ncbi.nlm.nih.gov]
  • We present the case of a preterm neonate who was born with respiratory distress and a papulovesicular rash that was diagnosed as congenital candidiasis (CC). The mother was asymptomatic.[ncbi.nlm.nih.gov]
  • We report an unusual case of duodenal candidiasis that presented as chronic diarrhea in a patient who had previously undergone kidney transplantation.[ncbi.nlm.nih.gov]
  • A rare case is presented of a recurring facial swelling occurring after a maxillofacial injury that did not resolve subsequent to medication and repeated aspirations. Cytospin preparations of the aspirate stained with Giemsa revealed candidiasis.[ncbi.nlm.nih.gov]
  • This case highlights that fungal infection should be considered when patients present with multiple abscesses, emphasizing the value of early biopsy to confirm diagnosis and facilitate precision treatment.[ncbi.nlm.nih.gov]
Candidiasis
  • The percentage of women diagnosed having vulvovaginal candidiasis or other conditions, proportions of women with vulvovaginal candidiasis compared between groups with and without a prior diagnosis of vulvovaginal candidiasis, and groups that read or did[ncbi.nlm.nih.gov]
  • Candidiasis in the vagina is commonly called a “vaginal yeast infection.” Other names for this infection are “vaginal candidiasis,” “vulvovaginal candidiasis,” or “candidal vaginitis.”[cdc.gov]
  • Candidiasis. Medscape Reference. October 2014; . Invasive Candidiasis. Centers for Disease Control and Prevention. February 2014; .[web.archive.org]
  • Symptoms of candidiasis vary depending on the area of the body that is infected. Candidiasis that develops in the mouth or throat is called “ thrush ” or oropharyngeal candidiasis.[web.archive.org]
Splenectomy
  • Case 3 illustrates treatment challenges, with ongoing dissemination and insufficient source control despite months of antifungal therapy, eventually resulting in a splenectomy.[ncbi.nlm.nih.gov]
Developmental Delay
  • We present a 16-year-old boy with global developmental delay who presented with this condition associated with candidal infection.[ncbi.nlm.nih.gov]
Intertrigo
  • The clinical diagnosis was intertrigo/candidiasis in 42.9% of patients.[emedicine.com]
  • ‘The differential diagnosis of erythrasma includes psoriasis, dermatophytosis, candidiasis, and intertrigo.’ ‘Treatment for persistent or recurrent candidiasis or trichomoniasis was repeated.’[en.oxforddictionaries.com]
  • Intertrigo : The patient has a history of intertrigo affecting any site in which skin surfaces are in close proximity, providing a warm and moist environment. A pruritic red rash develops.[emedicine.medscape.com]
Papule
  • Note satellite papules and involvement of intertriginous folds.[emedicine.medscape.com]
  • The appearance of the affected skin is variable; there may be: Red, moist skin area with a ragged, peeling edge and possibly pustules or papules at the margin. There may be satellite lesions (pustules or erythema) surrounding the margin.[patient.info]
Hyperhidrosis
  • Predisposing conditions include diabetes mellitus, obesity, and hyperhidrosis. Nails A chronic paronychia may be caused by one of several Candida species.[emedicine.medscape.com]
Delusion
  • Council on Scientific Affairs Report JAMA, 1992;268:3465 Chronic fatigue syndrome (Shafran) Am J Med 1991:90:730 Candidiasis hypersensit syndrome; Amer Acad Aller & Immunol position statement J Aller Clin Immunol 1986;78:271-3 Clinical ecology: science or delusion[ncahf.org]

Workup

  • Genitourinary candidiasis - A urinalysis should be performed; evidence of white blood cells (WBCs), red blood cells (RBCs), protein, and yeast cells is common; urine fungal cultures are useful Gastrointestinal candidiasis - Endoscopy with or without biopsy See Workup[emedicine.medscape.com]

Treatment

  • Short-course treatments should not be used for recurrent or resistant infections. Are Over-the-Counter Treatments Safe to Use? Over-the-counter treatments for VVC are available. As a result, more women are diagnosing and treating themselves.[web.archive.org]
  • Utilize este identificador para referenciar este registo: Título: Candidiasis: predisposing factors, prevention, diagnosis and alternative treatment Autor: Ferreira, Isabel C.F.R.[hdl.handle.net]
  • This review provides an overview on predisposition factors, prevention and diagnosis of candidiasis, highlighting alternative approaches for candidiasis treatment.[ncbi.nlm.nih.gov]
  • What Is the Treatment for Candida Osteoarticular Infections? What Is the Treatment for Candida Osteomyelitis? Recommendations 74.[doi.org]
  • Other management strategies and second-line treatments: Voriconazole (may be an alternative or a step-down treatment).[patient.info]

Prognosis

  • Prognosis of vaginal thrush The prognosis is good and most women with thrush will respond to antifungal treatment.[myvmc.com]
  • It is a very serious symptom, most of the time with a poor prognosis. Due to the weakness of the patient, the fungus spreads very quickly and can become fatal. Therefore, it’s key to be very alert to the early symptoms.[steptohealth.com]
  • […] organ (s) or body system is infected. [1] As of 2016, medical researchers are hoping T2 magnetic resonance testing will be able to more accurately and easily detect all forms of systemic candidiasis. [5] Last updated: 12/15/2016 The long-term outlook ( prognosis[rarediseases.info.nih.gov]
  • The prognosis is good for oral candidiasis with appropriate and effective treatment.[doi.org]

Etiology

  • Etiology Candidal vulvovaginitis is caused by inflammatory changes in the vaginal and vulvar epithelium secondary to infection with Candida species, most commonly Candida albicans .[ncbi.nlm.nih.gov]
  • The etiology of Crohn’s disease (CD), an autoimmune, inflammatory bowel disease (IBD) which affects approximately one million people in Europe, is still unclear.[doi.org]
  • Cultures from affected nails may help identify the etiologic agent responsible for onychomycosis versus other noninfectious causes.[emedicine.medscape.com]
  • Etiology Host factors that predispose patients to infections are numerous.[emedicine.com]

Epidemiology

  • The epidemiology of Candida fungal infections is on the rise and it is a common cause of systemic infections.[scialert.net]
  • The changing landscape of invasive fungal infections: epidemiology, diagnosis, and pharmacologic options. Clin Infect Dis. 2006. 43:S1-2. Kaufman DA.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Thrush represents an overgrowth of yeast when either normal host immunity or normal host flora has been disrupted. Yeast overgrowth on the oral mucosa causes the epithelial cells to desquamate.[pedclerk.bsd.uchicago.edu]
  • References: [1] [2] [3] [4] Pathophysiology Clinical features Local mucocutaneous Oropharyngeal ( oral thrush ) Pseudomembranous candidiasis White plaque in the oral cavity that can be scraped off , giving way to red, inflamed, or bleeding areas .[amboss.com]
  • Pathophysiology Candidal vulvovaginitis occurs when Candida species superficially penetrate the mucosal lining of the vagina and cause an inflammatory response. The dominant inflammatory cells are typically polymorphonuclear cells and macrophages.[ncbi.nlm.nih.gov]
  • Reviewed by: Linda Vorvick, MD, Family Physician, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine.[web.archive.org]
  • Pathophysiology Infections caused by Candida may affect numerous organ systems, such as the eyes, lungs, kidneys, heart, and CNS. Skin The most common manifestation of candidal infection is diaper dermatitis in infants.[emedicine.medscape.com]

Prevention

  • Utilize este identificador para referenciar este registo: Título: Candidiasis: predisposing factors, prevention, diagnosis and alternative treatment Autor: Ferreira, Isabel C.F.R.[hdl.handle.net]
  • Thus, the available evidence for the use of probiotics for prevention of recurrent VVC is limited.[ncbi.nlm.nih.gov]
  • This review provides an overview on predisposition factors, prevention and diagnosis of candidiasis, highlighting alternative approaches for candidiasis treatment.[ncbi.nlm.nih.gov]
  • This might prevent unnecessary surgery or inappropriate treatment. Timely diagnosis of hepatosplenic candidiasis (HSC) is challenging, but can prevent further complications and dissemination, and may even prevent unnecessary invasive procedures.[ncbi.nlm.nih.gov]
  • For women who experience recurrent yeast infections (more than three per year), some evidence suggests that oral or intravaginal probiotics may help to prevent frequent infections.[web.archive.org]

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