Presentation
It presents the postoperative histo tion of the Horsley-Clarke apparatus to reach targets ries of patients who have been cured or markedly re deep in the human brain introduced a new approach to lieved of longstanding afflictions; these persons have subcortical [books.google.com]
The clinical presentation of CO poisoning may be mild, moderate, or severe. [casesjournal.biomedcentral.com]
Respiratoric
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Pharyngitis
Laryngeal-pharyngeal dystonia as a possible cause of asphyxia with haloperidol treatment. Am J Psychiatry 1978 ; 135 : 1414 – 1415. 21. Ellenhorn, MJ, Barcelous, DG. Medical Toxicology. New York : Elsevier 1988. 22. [cambridge.org]
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Pharyngeal Dystonia
Laryngeal-pharyngeal dystonia as a possible cause of asphyxia with haloperidol treatment. Am J Psychiatry 1978 ; 135 : 1414 – 1415. 21. Ellenhorn, MJ, Barcelous, DG. Medical Toxicology. New York : Elsevier 1988. 22. [cambridge.org]
Neurologic
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Catatonia
Catatonia associated with phenylpropanoline overdose and fluphenazine treatment: case report. J Clin Psychiat 1985 ; 46 : 288 – 289. 119. Ross, RT. Young-age parkinsonism and common drugs. (Letter) Can J Neurol Sci 1989 ; 16 : 366 – 367. 120. [cambridge.org]
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Tic Disorder
Tic disorder was successfully treated with haloperidol. Thirty-three months after CO poisoning, the patient was asymptomatic and MRI revealed atrophy in caudate nucleus and putamen. The mechanism of tic disorder in CO intoxication is discussed. [em-consulte.com]
Workup
The utility of CAT in the diagnostic workup and in following clinical course is discussed, as are the difficulties of making a diagnosis of an antecedent primary psychiatric disorder in the presence of neurological and psychiatric sequelae of CO intoxication [ncbi.nlm.nih.gov]
Treatment
Imipramine in treatment of parkinsonism: a double blind placebo study. Br Med J 1965 ; 5452 : 33 – 34. 109. Reiderer, P, Reinolds, GP. Deprenyl is a selective inhibitor of brain MOA-B in the long term treatment of Parkinson’s disease. [cambridge.org]
Tremors Treatment There are several options available for the treatment of tremors. These include both medical as well as surgical treatments. [emedicinehealth.com]
Treatment for Parkinson's disease may include the following: Medications Surgery Stereotactic radiosurgery Robert Wood Johnson offers several innovative treatments for Parkinson's, including the Gamma Knife, as well as Deep Brain Stimulation. [rwjuh.edu]
Although treatments remain controversial, hyperbaric oxygen therapy (HBOT) is the most recommended treatment for severe acute CO poisoning [ 3, 4 ]. [ceemjournal.org]
Treatment Treatment of PD is usually with a combination of anti-Parkinson drugs, including levodopa, and auxilliary therapies like physical therapy. In Parkinsonism, treatment will be directed the cause, once it is identified. [pdring.com]
Prognosis
Any drug is not effective, but the prognosis is good. Copyright 2002 S. Karger AG, Basel [ncbi.nlm.nih.gov]
Prognosis; Complications Life expectancy is often about the same as for the general population, but female Parkinson's patients generally live longer with the disorder than men. [diagnose-me.com]
Miura T, Mitomo M, Kawai R, Harada K (1985) CT of the brain in acute carbon monoxide intoxication: characteristic features and prognosis. AJNR 6:739–742 Google Scholar 11. [link.springer.com]
Although anecdotal case reports have shown a good prognosis after induced hypothermia in patients with severe acute CO poisoning, the current clinical indications of induced hypothermia have not included acute CO poisoning [ 9, 10 ]. [ceemjournal.org]
Prognosis Slowly progressive with a mean duration of fifteen years. Severity, however, varies widely. It follows a relatively benign course in some patients, who may show little disability after twenty years. [patient.info]
Etiology
Etiology Heredity Antipsychotic drugs (or neuroleptic agents) Encephalitis infection in response to brain trauma, tumors, hydrocephalus or ischaemia Arteriosclerosis Neurotoxins such as cyanide, manganese and carbon monoxide Drugs like reserpine [slideshare.net]
Parkinson disease in twins: an etiologic study. JAMA. 1999 Jan 27. 281(4):341-6. [Medline]. Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, et al. [emedicine.medscape.com]
Epidemiology
Epidemiology of parkinsonism: incidence, classification, and mortality. Ann Neurol 1984 ; 16 : 278 – 282. 6. Eldridge, R, Rocca, WA. The clinical syndrome of striatal dopamine deficiency: parkinsonism induced by MPTP. [cambridge.org]
American Journal of Epidemiology, Vol. 144, September 1, 1996, pp. 480-84 Fahn, Stanley. An open trial of high-dosage antioxidants in early Parkinson's disease. [yourhealthbase.com]
Epidemiology [ 4 ] Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease. [patient.info]
Iqbal S, Clower JH, Hernandez SA, Damon SA, Yip FY (2012) A review of disaster-related carbon monoxide poisoning: surveillance, epidemiology, and opportunities for prevention. Am J Public Health 102:1957-1963. [headache.imedpub.com]
Epidemiology Frequency United States Unintentional, non–fire-related CO poisoning is responsible for approximately 15,000 emergency department visits annually in the United States. [emedicine.medscape.com]
Pathophysiology
The implications of these findings with regard to the central neurochemical pathophysiology in this patient and in major depressive disorder in general are discussed. [ncbi.nlm.nih.gov]
"Hypoxic-ischemic brain injury: pathophysiology, neuropathology and mechanisms." NeuroRehabilitation 26 (1): 5-13. Calvert, J. W. and J. H. Zhang (2005). "Pathophysiology of an hypoxic-ischemic insult during the perinatal period." [internationalbrain.org]
Pathophysiology of CO intoxication is complex. CO reacts readily and reversibly with hemoglobin that results in carboxyhemoglobin (CO-Hb). CO-Hb interferes with the transport of oxygen from alveoli to tissues. [em-consulte.com]
Perivascular and neuronal injuries arise by mechanisms other than hypoxia.(1,2) Neuropathology is due to a complex cascade of biochemical events involving several pathophysiologic processes,(3-10) some independent of pure hypoxic stress(11-13). [uhms.org]
Prevention
Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]
AND CONCLUSIONS Many lives could be saved and much disability prevented if citizens could learn to recognize and prevent the dangers of carbon monoxide poisoning. [carbonmonoxidekills.com]
0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis [medicbind.com]
These preventive measures may also be useful in slowing down the progression of the disease. [diagnose-me.com]
Treating underlying conditions, such as stroke or infections, can reduce symptoms or prevent the condition from getting worse. If symptoms make it hard to do everyday activities, the provider may recommend medicine. [medlineplus.gov]