The symptoms presented are those associated with bronchial obstruction, such as coughing, wheezing, and dyspnea. Over one-third of patients are asymptomatic and have an incidentally detected peripheral pulmonary nodule. [ncbi.nlm.nih.gov]

Herein, we present a case of a 28-year old female who presented with hemoptysis and was diagnosed with an IMT of lung in the first trimester of pregnancy. [lungindia.com]

We herein report a case of a resected typical carcinoid tumor that presented as a persistent p-GGN on HRCT. [surgicalcasereports.springeropen.com]

• Pain

  Carcinoid tumors in the lungs Signs and symptoms of carcinoid lung tumors include: Chest pain Wheezing Shortness of breath Diarrhea Redness or a feeling of warmth in your face and neck (skin flushing) Weight gain, particularly around the midsection and [mayoclinic.org]

  a tumour in the lung may cause a cough, which may make you cough up blood, and cause wheezing, shortness of breath, chest pain and tiredness a tumour in the stomach may cause pain, weight loss, tiredness and weakness Some tumours may not cause any symptoms [nhs.uk]

  […] slow growing tumors but are nevertheless capable of metastasizing. can be variable, dependent on the location: carcinoid tumors involving the jejunum and ileum can be large at presentation but are usually found incidentally rectal carcinoids may cause pain [radiopaedia.org]

  Recurrent pneumonia, hemoptysis, and chest pain are also common. [msdmanuals.com]

  And depending on where you get it, you could have a bunch of different symptoms, from pain in your belly to a bad cough. All carcinoid tumors, wherever they show up, affect cells that make hormones. [webmd.com]

• Weight Loss

  Snap Shot A 69-year-old male with a 50-pack-year smoking history presents with worsening cough, weight loss, and repeated episodes of hemoptysis. A chest radiograph is taken and shown at right. [medbullets.com]

  We present a 47-year-old male with a tobacco index of 9 and dyslipidemia, with a history of intermittent fever, cough with hyaline sputum, left scapular pain and 5 Kg weight loss in the past six months. [elsevier.es]

  loss, tiredness and weakness Some tumours may not cause any symptoms and are discovered by chance. [nhs.uk]

  […] of voice Signs and symptoms associated with Atypical Carcinoid Tumor of Lung, which may emerge during the later stages of the condition, include: High temperatures (fever) and excessive night sweats (may be recurrent) Sudden weight loss; unintentional [dovemed.com]

  loss Anybody can get lung cancer. [healthline.com]

• Pathologist

  A pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis. [dovemed.com]

  A pathologist will examine the sample under a microscope to determine if cancer cells are present. If cancer is detected, the pathologist will also be able to identify which type of lung cancer it is. Then the cancer can be staged. [healthline.com]

  […] bronchial tumors with Cushing syndrome Serotonin – whole blood preferred over serum Highly specific for carcinoid identification Not frequently used Neurokinin A – prognostic marker for midgut NETs Histology Definitive diagnosis requires biopsy and pathologist [arupconsult.com]

  The pathologist (the doctor who examines the biopsy or surgical tissue under the microscope) needs to be alert to the possible presence of a carcinoid tumor. [drugs.com]

  If adequate amounts of tissue are obtained, an experienced pathologist can diagnose carcinoid tumors by examining the tissue under a microscope. [medicinenet.com]

• Fever

  We present a 47-year-old male with a tobacco index of 9 and dyslipidemia, with a history of intermittent fever, cough with hyaline sputum, left scapular pain and 5 Kg weight loss in the past six months. [elsevier.es]

  There was no history of breathlessness, fever, anorexia or weight loss. She was in the first trimester of her third pregnancy. Her chest examination was unremarkable. A chest radiograph showed a well-circumscribed lesion in the left hilar region. [lungindia.com]

  He denies hemoptysis, fevers, chills, night sweats, weight loss, or diarrhea. During the past year, he occasionally experienced hot flashes after having a hot shower. He also notes intermittent abdominal pain, but he is otherwise healthy. [clevelandclinicmeded.com]

  (a genetic disorder) are risk factors in some individuals Atypical Carcinoid Tumor of Lung arises more often in the proximal airways of the lung and can cause chest pain, breathing difficulties, fatigue, and other general signs and symptoms, such as fever [dovemed.com]

  Persons with carcinoid lung tumors may complain of the following symptoms: Cough that does not go away Coughing up blood Difficulty in breathing Wheezing Fever (due to infection in the lung) Sometimes the health care practitioner considers the possibility [emedicinehealth.com]

• Lymphadenopathy

  It was accompanied by a single lymphadenopathy in the subcarinal region, with a short axis larger than 1 cm. Abdominal study was normal. [archbronconeumol.org]

  No pleural effusion and no mediastinal lymphadenopathy. Cytological Images: Cytological speciemen: Bronchial brushing Cytological Report: Presence of many tumor cells, small-medium sized, with finely granular chromatin pattern. [icytology.wordpress.com]

  Lymphadenopathy and distant metastasis are also less common with peripheral bronchial carcinoids. [humpath.com]

  Keywords Carcinoid Lymphadenopathy Mitosis Background Pulmonary carcinoid tumors make up approximately 1–2 % of all pulmonary tumors [ 1 ]. They are derived from the Kulchitsky cell and generally have indolent growth patterns. [cardiothoracicsurgery.biomedcentral.com]

• Cough

  The symptoms presented are those associated with bronchial obstruction, such as coughing, wheezing, and dyspnea. Over one-third of patients are asymptomatic and have an incidentally detected peripheral pulmonary nodule. [ncbi.nlm.nih.gov]

  When symptoms are present, usually there is coughing or wheezing. The cough might produce blood in the phlegm or sputum. If the tumor is large enough to block an air passage, a person might develop an infection called post-obstructive pneumonia. [my.clevelandclinic.org]

  Lung carcinoids typically present with a cough or hemoptysis. Findings may closely mimic malignant tumours of the lung, i.e. lung cancer. The definitive diagnosis is rendered by a microscopic examination, after excision. [en.wikipedia.org]

  Coughing up blood Wheezing Difficulty breathing Skin flushing, where the skin on the face and upper chest turns pinkish, red, or purple, and feels hot Causes of Carcinoid Tumors As with many cancers, it is unclear exactly what causes carcinoid tumors [bmc.org]

• Dyspnea

  The symptoms presented are those associated with bronchial obstruction, such as coughing, wheezing, and dyspnea. Over one-third of patients are asymptomatic and have an incidentally detected peripheral pulmonary nodule. [ncbi.nlm.nih.gov]

  Half of patients are asymptomatic, and half present with symptoms of airway obstruction, including dyspnea, wheezing, and cough, which often leads to a misdiagnosis of asthma. Recurrent pneumonia, hemoptysis, and chest pain are also common. [msdmanuals.com]

  In symptomatic patients, the most common clinical findings are those associated with bronchial obstruction, such as persistent atelectasis, recurrent pneumonia, persistent cough, wheezing, hemoptysis, or dyspnea. [clevelandclinicmeded.com]

  Clinical Observations A 43-year-old male came to our emergency department due to moderate-exertion dyspnea that had been evolving over the previous 24 h, accompanied by pleuritic chest pain and cough with hemoptoic expectoration (75 cm 2 while at home [archbronconeumol.org]

• Dry Cough

  A 28-year-old lady presented with dry cough for 2 years and hemoptysis for 1 week. She had three episodes of hemoptysis (100 ml per episode). There was no history of breathlessness, fever, anorexia or weight loss. [lungindia.com]

• Abdominal Pain

  These may include persistent cough or hoarseness, for tumors in the lungs; or abdominal pain, cramping, nausea, vomiting, or changes in bowel movements, for tumors in the small intestine. [blog.dana-farber.org]

  […] gastrointestinal tract carcinoid can present as vague abdominal pain carcinoid syndrome : in 8% of patients with a carcinoid tumor 9 Location gastrointestinal tract carcinoid (60-85% of all carcinoids) 11,12 small bowel : ~40% of gastrointestinal carcinoids [radiopaedia.org]

  CT and MRI ( magnetic resonance imaging ) scans are commonly used in the evaluation of abdominal pain, weight loss, abnormal liver tests, and other symptoms. [medicinenet.com]

  […] upper back Pink or purple marks on the skin that look like stretch marks Carcinoid tumors in the digestive tract Signs and symptoms of carcinoid tumors in the digestive tract include: Abdominal pain Diarrhea Nausea, vomiting and inability to pass stool [mayoclinic.org]

  pain (often secondary to fibrosis) Gastric carcinoids Type 1 associated with chronic atrophic gastritis – absent acid secretion and hypergastrinemia Type 2 associated with Zollinger-Ellison syndrome, hypergastrinemia, and MEN1 Type 3 sporadic – normal [arupconsult.com]

• Nausea

  These may include persistent cough or hoarseness, for tumors in the lungs; or abdominal pain, cramping, nausea, vomiting, or changes in bowel movements, for tumors in the small intestine. [blog.dana-farber.org]

  […] gain, particularly around the midsection and upper back Pink or purple marks on the skin that look like stretch marks Carcinoid tumors in the digestive tract Signs and symptoms of carcinoid tumors in the digestive tract include: Abdominal pain Diarrhea Nausea [mayoclinic.org]

  In January 2011, the patient complained of fatigue on progressively less exertion and showed disease progression with worsening liver lesions; oral chemotherapy was begun with capecitabine, but was discontinued after four cycles due to intolerance (nausea [revportcardiol.org]

  For carcinoid tumors of the gastrointestinal system, symptoms may include: diarrhea or constipation nausea abdominal or rectal pain rectal bleeding For carcinoid tumors of the lungs, symptoms may include: chest pain wheezing or shortness of breath skin [stopcancerfund.org]

  Side effects of chemo include nausea, vomiting, hair loss, loss of appetite, and a higher risk for infections. Continued Chemoembolization. It's a treatment used to treat a carcinoid tumor that has spread to the liver. [webmd.com]

• Rectal Bleeding

  bleeding Rectal pain Redness or a feeling of warmth in your face and neck (skin flushing) When to see a doctor If you experience any signs and symptoms that bother you and are persistent, make an appointment with your doctor. [mayoclinic.org]

  Symptoms caused by the tumour Symptoms will depend on where in the body the tumour develops: a tumour in the bowel may cause tummy pain, a blocked bowel ( diarrhoea, constipation, feeling sick or being sick) and bleeding from the bottom (rectal bleeding [nhs.uk]

  For carcinoid tumors of the gastrointestinal system, symptoms may include: diarrhea or constipation nausea abdominal or rectal pain rectal bleeding For carcinoid tumors of the lungs, symptoms may include: chest pain wheezing or shortness of breath skin [stopcancerfund.org]

  Rectal: Most of the tumors of the rectum are discovered during colonoscopy or during a digital rectal exam. Occasionally, there can be rectal bleeding or pain. Carcinoid syndrome is rare. [oncolink.org]

  Patients who are symptomatic usually present with rectal bleeding, pain, or constipation. Treatment For tumors less than 1 cm in diameter, local excision is indicated. [atlasgeneticsoncology.org]

• Constipation

  Symptoms caused by the tumour Symptoms will depend on where in the body the tumour develops: a tumour in the bowel may cause tummy pain, a blocked bowel ( diarrhoea, constipation, feeling sick or being sick) and bleeding from the bottom (rectal bleeding [nhs.uk]

  For carcinoid tumors of the gastrointestinal system, symptoms may include: diarrhea or constipation nausea abdominal or rectal pain rectal bleeding For carcinoid tumors of the lungs, symptoms may include: chest pain wheezing or shortness of breath skin [stopcancerfund.org]

  For instance, if you've got the tumors in your GI tract, you might notice things like this happening to you: Pain in your belly Diarrhea Constipation Feel nauseated or throw up Can't breathe right Get blood in your stool Lose weight If you have a lung [webmd.com]

  Patients who are symptomatic usually present with rectal bleeding, pain, or constipation. Treatment For tumors less than 1 cm in diameter, local excision is indicated. [atlasgeneticsoncology.org]

• Rectal Pain

  […] due to intestinal blockage (bowel obstruction) Rectal bleeding Rectal pain Redness or a feeling of warmth in your face and neck (skin flushing) When to see a doctor If you experience any signs and symptoms that bother you and are persistent, make an [mayoclinic.org]

  For carcinoid tumors of the gastrointestinal system, symptoms may include: diarrhea or constipation nausea abdominal or rectal pain rectal bleeding For carcinoid tumors of the lungs, symptoms may include: chest pain wheezing or shortness of breath skin [stopcancerfund.org]

  Rectal: Most of the tumors of the rectum are discovered during colonoscopy or during a digital rectal exam. Occasionally, there can be rectal bleeding or pain. Carcinoid syndrome is rare. [oncolink.org]

• Chest Pain

  Recurrent pneumonia, hemoptysis, and chest pain are also common. [msdmanuals.com]

  Carcinoid tumors in the lungs Signs and symptoms of carcinoid lung tumors include: Chest pain Wheezing Shortness of breath Diarrhea Redness or a feeling of warmth in your face and neck (skin flushing) Weight gain, particularly around the midsection and [mayoclinic.org]

  a tumour in the lung may cause a cough, which may make you cough up blood, and cause wheezing, shortness of breath, chest pain and tiredness a tumour in the stomach may cause pain, weight loss, tiredness and weakness Some tumours may not cause any symptoms [nhs.uk]

  For carcinoid tumors of the gastrointestinal system, symptoms may include: diarrhea or constipation nausea abdominal or rectal pain rectal bleeding For carcinoid tumors of the lungs, symptoms may include: chest pain wheezing or shortness of breath skin [stopcancerfund.org]

  These are some of the most common symptoms of lung cancer: persistent or worsening cough wheezing coughing up blood and mucus chest pain that gets worse when you take a deep breath, laugh, or cough shortness of breath hoarseness weakness, fatigue frequent [healthline.com]

• Hypotension

  Other features include diarrhoea, abdominal pain, palpitations, hypotension and wheezing. [patient.info]

  Rapid heartbeat (tachycardia) and decreased blood pressure (hypotension) : Dilation of blood vessels can lead to a rapid heartbeat and a drop in blood pressure. [oncolink.org]

• Bone Pain

  Bone scan. In approximately 10% of patients with carcinoid tumors the tumor metastasizes to the bones and can cause bone pain. Bone scans using radioactive phosphate are accurate for detecting these bony metastases. [medicinenet.com]

  Interferon alfa is a useful additive therapy when symptoms of carcinoid syndrome do not resolve with a somatostatin analogue alone. [ 4 ] External beam radiotherapy may relieve bone pain from metastases. [ 6 ] Chemoembolisation of the hepatic artery may [patient.info]

• Dizziness

  The symptoms of carcinoid syndrome include: flushing of the skin diarrhoea wheezing a fast heart beat dizziness due to sudden low blood pressure Drinking alcohol can bring on the symptoms in some people with carcinoid. [cancerresearchuk.org]

  […] chest pain that gets worse when you take a deep breath, laugh, or cough shortness of breath hoarseness weakness, fatigue frequent or persistent attacks of bronchitis or pneumonia Symptoms that cancer has spread may include: hip or back pain headache, dizziness [healthline.com]

Participants with positive findings received high-resolution CT and additional diagnostic workup as appropriate. [asbestslachtoffers.nl]

Now we obtain positron emission tomography – computed tomography (PET-CT) scans during the preoperative workup of our patients. [cardiothoracicsurgery.biomedcentral.com]

The treatment of carcinoid tumors is complete surgical removal and a more aggressive approach is required in the treatment of atypical carcinoids. A case is presented with a review of the literature. [ncbi.nlm.nih.gov]

The treatment of choice is surgery for localized disease. In advanced or metastatic disease no effective medical treatment exists ( 10, 11 ). [jtd.amegroups.com]

Similarly, no patient received adjuvant treatment in the early postoperative period. All patients who experienced recurrent disease received chemotherapy and/or radiation treatment. [cardiothoracicsurgery.biomedcentral.com]

Treatment Surgery is often used as the first treatment for carcinoid tumors. If the tumor hasn’t spread, surgery can cure the cancer. Surgery may also be combined with other treatments to reduce the tumor and the symptoms. [stopcancerfund.org]

There is one previous case report of a high-grade SpCC after treatment of a primary pulmonary collision carcinoid tumor and another report of SpCC of the lung after treatment of a large cell NE carcinoma [ 1, 8 ]. [jsms.sch.ac.kr]

Although carcinoid tumors are generally felt to be of low grade malignancy, an atypical variant exists that exhibits more virulent behavior and a less favorable prognosis. [ncbi.nlm.nih.gov]

The prognosis of the condition generally depends upon whether the tumor is classified as typical or atypical. [dovemed.com]

Small cell lung cancer is the most common subgroup, with rapid progression, aggressive metastatic potential and the worst prognosis. Large cell neuroendocrine carcinoma is rare but also has a poor prognosis. [npplweb.com]

Prognosis depends on site. [patient.info]

Etiology WS2 is genetically very heterogeneous and still much of the etiology of WS2 remains elusive. Mutations have been found in MITF (3p14-p13; subtype designated as WS2A), SNAI2 (8q11.21; WS2D), and SOX10 (22q13.1; WS2E) genes. [orpha.net]

This definition is non-specific and does not necessarily reflect the pathological etiology of p-GGN. [surgicalcasereports.springeropen.com]

Disease Bronchial / Lung Carcinoid Etiology Lung and bronchial carcinoids are diagnosed most commonly in septuagenarians and are associated with smoking. [atlasgeneticsoncology.org]

Etiology In the past, pulmonary carcinoid tumors were believed to be derived from neural crest cells; however, they currently are understood to be of endodermal origin, arising from stem cells of the bronchial epithelium known as Kulchitsky cells. [emedicine.medscape.com]

(Etiology) The exact cause of Atypical Carcinoid Tumor of Lung is unknown, but it may develop from preinvasive lesions such as diffuse idiopathic pulmonary neuroendocrine hyperplasia (DIPNECH). [dovemed.com]

Summary Epidemiology The prevalence of WS2 is unknown; the worldwide prevalence of WS is estimated at around 1/40,000. WS2 is one of the most common types of Waardenburg syndrome. [orpha.net]

*SEER= Surveillance, Epidemiology, and End Results [cancer.org]

Disease Small Intestinal Carcinoid Epidemiology Small intestinal carcinoid tumors account for approximately one third of all small bowel tumors. They comprise 29% of GI carcinoids. [atlasgeneticsoncology.org]

[…] indicated Bronchial carcinoids – see recommendations for non-small cell lung cancer (NSCLC) Chest x-ray, CBC, and chemistries every 3-6 months for first 2 years CT recommended every 6 months for 2-3 years in NSCLC Echocardiogram – every 2-3 years Background Epidemiology [arupconsult.com]

The epidemiological, surgical and pathological features of brain metastases from carcinoid tumors are also discussed from the analysis of 44 well-documented cases reported in the literature. brain metastasis carcinoid tumor This is a preview of subscription [link.springer.com]

NETs of the lung, thymus, and stomach von Hippel-Lindau syndrome – pancreatic neoplasia of neuroendocrine origin occurs in ~15% of cases Neurofibromatosis type 1 (von Recklinghausen disease) – infrequent carcinoids of the duodenum Tuberous sclerosis Pathophysiology [arupconsult.com]

[…] small foci of atypical hyperplastic bronchial epithelium in adjacent locations), which may represent local metastatic disease or an entirely different histologic abnormality and, when present, may indicate a more aggressive tumor and a poorer prognosis Pathophysiology [emedicine.medscape.com]

Downloadable PDFs Download free PDFs of our lung carcinoid tumor information About and Key Statistics Causes, Risks, Prevention Detection, Diagnosis, Staging Treatment and Side Effects Next Steps After Treatment More Resources READ MORE Lung Cancer Prevention [cancer.org]

Prevention Unlike most lung tumors, carcinoid tumors have not been associated with smoking, air pollution, or exposure to chemicals. There are no known ways to prevent this type of cancer. [drugs.com]

When the cancer cells grow too fast, they prevent your organs from working normally. [lung.org]

In many cases, as in this one, thickening of the leaflets and subvalvular apparatus leads to retraction of the leaflets, which become fixed, preventing coaptation and leaving the valve in a semi-open position. [revportcardiol.org]

How can I prevent carcinoid tumors? Presently, there is no way to prevent carcinoid tumors. There may be an association between carcinoid tumors and smoking, hence not starting or quitting smoking may reduce the risk of developing carcinoid tumors. [oncolink.org]