Presentation
Presentation is often insidious, and a large proportion (50%) of patients may be asymptomatic at the time of detection 1. Alternatively, as these tumors can produce large quantities of mucus, patients may present with bronchorrhea. [radiopaedia.org]
In contrast, bowenoid papulosis has a completely benign course with no present evidence suggesting the potential for malignant degeneration. [pubmed.ncbi.nlm.nih.gov]
We present results of a multicentre study measuring UBC®Rapid Test in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS) and high-grade bladder cancer. [refubium.fu-berlin.de]
For people who do present with a lump or nipple discharge, other methods of diagnosis may be applied such as an ultrasound scan, a core biopsy or fine needle aspiration biopsy. [news-medical.net]
Some patients present with such extensive DCIS that it may already contain areas of invasion, and mastectomy may be felt necessary to control the process in a person with years of expected survival. [cancernetwork.com]
Neurologic
- Confusion
Abstract Bowen's disease, erythroplasia of Queyrat and bowenoid papulosis are uncommon disorders of the anogenital skin that may be confused with a variety of other lesions. [pubmed.ncbi.nlm.nih.gov]
Treatment
One possible treatment is surgical removal of the cells with cryotherapy. What are the signs of eye cancer, and what is the treatment? Learn more here. [medicalnewstoday.com]
After surgery, you may need other treatments. These are called adjuvant treatments and can include radiotherapy and, in some cases, hormone therapy. [breastcancernow.org]
Types of treatment of DCIS include: Surgery - This is the most commonly recommended treatment for DCIS and includes removal of the entire cancer. [news-medical.net]
Results: All patients showed excellent toleration of the treatment without any side effects. Treatment resulted in complete eradication of tumor cells in 3 patients and persistent tumor detection in the other 6 patients. [ec.europa.eu]
Prognosis
Mucinous subtypes have worse prognosis 4, probably due to aerogenous spread that forms infiltrating, multifocal, or satellite tumors 11. [radiopaedia.org]
Although DCIS is an early form of breast cancer with a very good prognosis, people understandably may feel very anxious and frightened by the diagnosis. [breastcancernow.org]
Prognosis in infiltrating lobular carcinoma. An analysis of "classical" and variant tumors. Am J Surg Pathol 1990; 14: 12-23. https://doi.org/10.1097/00000478-199001000-00002 Mohsin SK, O'Connell P, Allred DC, Libby AL. [medicinaylaboratorio.com]
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A. 2009 Aug 18. 106(33):14016-21. [Medline]. [Full Text]. [medscape.com]
Etiology
Squamous cell carcinoma of the bilharzial and non-bilharzial urinary bladder: a review of etiological features, natural history, and management. Int J Clin Oncol. 2005 Feb. 10(1):20-5. [Medline]. Heyns CF, van der Merwe A. Bladder cancer in Africa. [medscape.com]
Epidemiology
There is also evidence from epidemiological studies that there is an inherited predisposition to DCIS. [breast-cancer-research.biomedcentral.com]
Breast ductal carcinoma in situ: Epidemiology, clinical manifestations, and diagnosis. https://www.uptodate.com/contents/search. Accessed May 9, 2018. Distress management. [mayoclinic.org]
Bilateral risk for subsequent breast cancer after lobular carcinoma-in-situ: analysis of surveillance, epidemiology, and end results data. [medicinaylaboratorio.com]
Recurrence and progression of disease in non-muscle-invasive bladder cancer: from epidemiology to treatment strategy. Eur Urol. 2009 Sep. 56(3):430-42. [Medline]. [medscape.com]
Prevention
Cumulatively, our data support further development of MNK1 inhibitors as therapeutics for preventing invasive disease. Received May 24, 2018. Revision received November 2, 2018. Accepted January 10, 2019. [cancerres.aacrjournals.org]
[…] women with carcinoma in situ continues to increase and comprises approximately 25% of all ‘malignancy’ detected through screening Localised DCIS can be treated by breast-conserving surgery with or without radiotherapy The role of hormone therapy in preventing [bmj.com]
[…] example, a personal or family history of cancer the age of the person other health conditions personal preferences Treatment options A doctor may recommend different types of surgery, such as:- open surgery, such as a mastectomy for breast cancer or a preventive [medicalnewstoday.com]
Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med. 2011;364:2381-91. 8. Silverstein MJ. The University of Southern California/Van Nuys prognostic index for ductal carcinoma in situ of the breast. [cancernetwork.com]