Presentation is often insidious, and a large proportion (50%) of patients may be asymptomatic at the time of detection 1. Alternatively, as these tumors can produce large quantities of mucus, patients may present with bronchorrhea. [radiopaedia.org]

We present results of a multicentre study measuring UBC Rapid Test in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS) and high-grade bladder cancer. [refubium.fu-berlin.de]

Some patients present with such extensive DCIS that it may already contain areas of invasion, and mastectomy may be felt necessary to control the process in a person with years of expected survival. [cancernetwork.com]

This finding supports the genetic predisposition data presented here, with ER and grade-specific loci in DCIS having similar specificity in IDC. [breast-cancer-research.biomedcentral.com]

Presented at the American Society of Clinical Oncology 2018 Annual Meeting. 2018 Jun 03. Chicago, IL. [Full Text]. Rosenberg JE, O'Donnell PH, Balar AV, McGregor BA, Heath EI, Yu EY, et al. [medscape.com]

• Squamous Metaplasia of the Bladder

  Keratinizing squamous metaplasia of the bladder: a review. Urol Int. 2008. 81(3):247-51. [Medline]. Khan MS, Thornhill JA, Gaffney E, Loftus B, Butler MR. [medscape.com]

One possible treatment is surgical removal of the cells with cryotherapy. What are the signs of eye cancer, and what is the treatment? Learn more here. [medicalnewstoday.com]

After surgery, you may need other treatments. These are called adjuvant treatments and can include radiotherapy and, in some cases, hormone therapy. [breastcancernow.org]

Results: All patients showed excellent toleration of the treatment without any side effects. Treatment resulted in complete eradication of tumor cells in 3 patients and persistent tumor detection in the other 6 patients. [ec.europa.eu]

However, solid, invasive components are frequently present and despite radical treatment, recurrence rates are high. [radiopaedia.org]

These intravesical treatments are not effective in the 20% of patients in whom cancer has invaded the bladder wall muscle; those cases require cystectomy or a combination of radiation therapy and chemotherapy (see Treatment ). [medscape.com]

Mucinous subtypes have worse prognosis 4, probably due to aerogenous spread that forms infiltrating, multifocal, or satellite tumors 11. [radiopaedia.org]

Although DCIS is an early form of breast cancer with a very good prognosis, people understandably may feel very anxious and frightened by the diagnosis. [breastcancernow.org]

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A. 2009 Aug 18. 106(33):14016-21. [Medline]. [Full Text]. [medscape.com]

Squamous cell carcinoma of the bilharzial and non-bilharzial urinary bladder: a review of etiological features, natural history, and management. Int J Clin Oncol. 2005 Feb. 10(1):20-5. [Medline]. Heyns CF, van der Merwe A. Bladder cancer in Africa. [medscape.com]

There is also evidence from epidemiological studies that there is an inherited predisposition to DCIS. [breast-cancer-research.biomedcentral.com]

Recurrence and progression of disease in non-muscle-invasive bladder cancer: from epidemiology to treatment strategy. Eur Urol. 2009 Sep. 56(3):430-42. [Medline]. [medscape.com]

Cumulatively, our data support further development of MNK1 inhibitors as therapeutics for preventing invasive disease. Received May 24, 2018. Revision received November 2, 2018. Accepted January 10, 2019. [cancerres.aacrjournals.org]

[…] women with carcinoma in situ continues to increase and comprises approximately 25% of all ‘malignancy’ detected through screening Localised DCIS can be treated by breast-conserving surgery with or without radiotherapy The role of hormone therapy in preventing [bmj.com]

A doctor may recommend different types of surgery, such as:- open surgery, such as a mastectomy for breast cancer or a preventive hysterectomy for cervical cancer laser surgery loop electrosurgical excision procedure (LEEP/LEETZ) cold knife conization [medicalnewstoday.com]

Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med. 2011;364:2381-91. 8. Silverstein MJ. The University of Southern California/Van Nuys prognostic index for ductal carcinoma in situ of the breast. [cancernetwork.com]

Bojesen Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA Song Yao Roswell Park Cancer Institute, Buffalo, NY, USA Christine B. [breast-cancer-research.biomedcentral.com]