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Carcinoma of the Breast


Presentation

  • It typically presents a diagnostic challenge masquerading as carcinoma or other primary disease of the breast.[ncbi.nlm.nih.gov]
Rigor
  • If a woman does have the mutation, she may choose to undergo more rigorous screening or even undergo preventive (prophylactic) mastectomy to decrease her chances of developing breast cancer.[oncolink.org]
Ptosis
  • Myasthenia gravis - symptoms of pupil-sparing ocular motility disorder and ptosis may invoke consideration for ocular myasthenia gravis.[eyewiki.aao.org]
Vaginal Dryness
  • When taking tamoxifen, patients may experience weight gain, hot flashes, vaginal dryness, and discharge. Taking tamoxifen may also increase risk of serious medical issues, such as blood clots, stroke, and uterine cancer.[oncolink.org]
Confusion
  • This breast change is not a cancer, though the name can be confusing. In LCIS, cells that look like cancer cells are growing in the lobules of the milk-producing glands of the breast, but they don’t grow through the wall of the lobules.[cancer.org]
  • People can be confused by this term, thinking it’s a different kind of cancer. In reality, it’s just a broader category—like calling someone from Los Angeles a Californian.[drsusanloveresearch.org]
  • After years of effort invested in encouraging mammography, to reverse course would cause widespread confusion and anger.[theatlantic.com]
  • A cancer diagnosis can be very confusing time. There are many different cancers so it is important to find out information that is relevant to you.[cancerwa.asn.au]
  • That's confusing to patients conditioned to treat every cancer diagnosis as an emergency, in a world that still reacts to cancer as though it's the beginning of the end and in a culture where we don't talk about death until we have to.[time.com]

Workup

  • Patients require a systemic workup to evaluate for metastases to other organ systems, and a multidisciplinary team including oncology, radiation oncology, and ophthalmology are necessary.[eyewiki.aao.org]
  • Developing the best treatment plan depends on a good, thorough pathologic evaluation as well as a complete workup of both breasts, as noted above.[medicinenet.com]
  • (See Workup.) Increased public awareness and improved screening have led to earlier diagnosis, at stages amenable to complete surgical resection and curative therapies.[emedicine.medscape.com]

Treatment

  • All relevant aspects of the patient's history, treatment, and outcomes were documented. The aim was compare treatment outcomes of tubular breast cancer outcomes to that of all invasive breast cancers.[ncbi.nlm.nih.gov]

Prognosis

  • It has favorable biological characteristics and an excellent prognosis. A 77-year-old woman presented with a lump in the right breast.[ncbi.nlm.nih.gov]

Etiology

  • Etiology and pathogenesis of this type of lesion in the breast is uncertain. The most common sources of metastatic squamous cell carcinoma of the breast are lung, esophagus, cervix, and urinary bladder.[ncbi.nlm.nih.gov]
  • ICD-10-CM Codes › C00-D49 Neoplasms › C50-C50 Malignant neoplasms of breast › Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10data.com]
  • Although the outcome of our patient population reaffirms differences between the two groups the etiology of the perceived aggressiveness of this phenotype remains undetermined.[omicsonline.org]
  • These data support the evidence that some breast cancers share etiologic factors with ovarian cancer.[emedicine.medscape.com]

Epidemiology

  • The purpose of this study is to describe the epidemiology and survival of this rare malignancy.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Squamous cell carcinoma of the breast is a rare entity and as such knowledge about the pathophysiology, treatment and prognosis are still uncertain.[ncbi.nlm.nih.gov]
  • G. , Inadequate corpus luteum function: A pathophysiological interpretation of human breast cancer epidemiology, Cancer 33 , 1306–1312 (1974).[link.springer.com]
  • Types of invasive breast carcinoma include ductal, lobular, and mixed. [5] Pathophysiology To date, the basis for breast carcinoma as the most common primary metastatic process to the orbit is unclear.[eyewiki.aao.org]
  • Pathophysiology The current understanding of breast cancer etiopathogenesis is that invasive cancers arise through a series of molecular alterations at the cell level.[emedicine.medscape.com]

Prevention

  • […] and early detection of cervical cancer: American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer.[nccn.org]
  • WHO promotes breast cancer control within the context of national cancer control programmes and integrated to noncommunicable disease prevention and control.[who.int]
  • Preventative surgery (prophylactic mastectomy) may also prevent breast cancer. Bilateral prophylactic mastectomy is the removal of both breasts in order to prevent breast cancer.[onhealth.com]
  • Preventive Services Task Force Recommendation Statement. U.S. Preventive Services Task Force. Annals of Internal Medicine. November 17, 2009 vol. 151 no. 10 716-726. Available online at . Accessed November 2009. (Modified 2011 July 27).[labtestsonline.it]
  • Winer view details of 4th ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4) Breast cancer, Gynaecologic malignancies Prevention and Screening in BRCA Mutation Carriers and Other Breast/Ovarian Hereditary Cancer Syndromes:[esmo.org]

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