Presentation
Subtle signs of extramuscular inflammation may also be present if carefully sought. [musculoskeletalkey.com]
IAC metastasis with LC in the present patient was identified most clearly with a high-resolution T2 image. [omicsonline.org]
Abstract A 58-year-old woman who had presented with intestinal pseudo-obstruction died 9 months later from rapidly progressive neurologic symptoms and autonomic insufficiency. [annals.org]
Polymyositis presents clinically with weakness of proximal limb muscles and facial muscles, ptosis, and dysphagia. [somalidoc.com]
Orphanet J Rare Dis. 2007;22-. [ PubMed ] Braik T, Evans AT, Telfer M, Paraneoplastic neurological syndromes: unusual presentations of cancer. A practical review. [jtd.amegroups.com]
Entire Body System
- Gangrene
J Neurol. 2008;1085-7. [ PubMed ] Kucuk O, Noskin G, Petersen K, Lower extremity vasospasm associated with ischemic neuropathy, dermal fibrosis, and digital gangrene in a patient with carcinoid syndrome. [jtd.amegroups.com]
Respiratoric
- Pharyngitis
Swallowing rehabilitation after oro-pharyngeal resection for squamous cell carcinoma. Br J Oral Maxillofac Surg 2000; 38:513-518. 17. Kugaya A, Akechi T, Okuyama T, et al. [jpgmonline.com]
Gastrointestinal
- Dysphagia
Polymyositis presents clinically with weakness of proximal limb muscles and facial muscles, ptosis, and dysphagia. [somalidoc.com]
Other skeletal muscles can be affected, and 20% of patients have dysphagia (with nasal regurgitation of liquids signifying greater severity), while a smaller subset experiences respiratory insufficiency from respiratory muscle weakness. [musculoskeletalkey.com]
Syndromes: Anatomic Orbital: Frontal headache; EOM paresis; Trigeminal 1 sensory loss; Proptosis Parasellar: Frontal headache; EOM paresis; Trigeminal 1 sensory loss Middle fossa: Facial pain; Trigeminal sensory loss± VII palsy Jugular foramen: Hoarseness; Dysphagia [neuromuscular.wustl.edu]
[…] regulate BP Glossopharyngeal neuropathy Tumor or aneurysm in the posterior fossa or jugular foramen Vagus (10th) Moves vocal cords and muscles for swallowing Transmits impulses to the heart and smooth muscles of visceral organs Hoarseness, dysphonia, and dysphagia [merckmanuals.com]
Eyes
- Diplopia
If diplopia persists when one eye is closed (monocular diplopia), the cause is probably a nonneurologic eye disorder. If diplopia disappears when either eye is closed (binocular diplopia), the cause is probably a disorder of ocular motility. [merckmanuals.com]
VI) Proximal Muscle Weakness Myasthenia gravis (autoimmune, voluntary muscle fatigue esp extraocular and cranial muscles, ptosis, diplopia, dysarthria, leg weakness, normal DTRs, asymetric; Dx - Edrophonium [Tensilon] Test - not with asthmatics), Polymyositis [med-ed.virginia.edu]
Musculoskeletal
- Myopathy
Myopathy due to magnesium deficiency Myopathy due to polyarteritis nodosa Myopathy in myasthenia gravis Nutritional myopathy Potassium depletion myopathy Primary familial amyloid myopathy Primary sporadic amyloid myopathy Secondary myopathy Secondary [icdlist.com]
Holonyms for carcinomatous myopathy No holonyms found for carcinomatous myopathy. Hyponyms for carcinomatous myopathy No hyponyms found for carcinomatous myopathy. [wordphd.com]
English Definition Of Carcinomatous Myopathy The word Carcinomatous Myopathy is a noun 1. [whatwordis.com]
The majority of congenital myopathies are named after the structural abnormalities seen on muscle biopsy, e.g. central core disease, nemaline body myopathy, myotubular myopathy, congenital fibre-type disproportion. [somalidoc.com]
[…] of carcinomatous myopathy in Pythagorean Numerology is: 5 Images & Illustrations of carcinomatous myopathy Translation Find a translation for the carcinomatous myopathy definition in other languages: Select another language: Discuss these carcinomatous [definitions.net]
- Muscle Weakness
Polymyositis presents clinically with weakness of proximal limb muscles and facial muscles, ptosis, and dysphagia. [somalidoc.com]
Abstract Two patients are described with proximal muscle weakness and electromyographic evidence of a myopathic process. In both, discrete carcinomatous metastatic deposits were found in proximal muscles. [unboundmedicine.com]
Both of these diseases can cause proximal muscle weakness, but can be separated from polymyositis/dermatomyositis by their characteristic electromyographic patterns as well as absence of serum muscle enzyme elevation. [itsmyositis.blogspot.com]
[…] daily routine) ( 2 ); the location of weakness (proximal muscles in PM and DM vs. distal muscles in IBM and other disorders; symmetric weakness in PM and DM vs. asymmetric muscle involvement in IBM and other disorders) ( 3 ); the time frame and tempo [musculoskeletalkey.com]
Proximal dominant muscle weakness attributed to steroid myopathy was reported in a patient with an ACTH releasing thymic carcinoid ( 15 ). [jtd.amegroups.com]
- Myalgia
Since patients may use “weakness” and “pain” interchangeably, questions should focus on ( 1 ) distinguishing myalgias from true weakness, which is often painless, by focusing on the patients’ functional abilities (what they can and cannot do in their [musculoskeletalkey.com]
Cholesterol emboli Predisposing events Vascular catheterization Anticoagulant therapy Aortic atherosclerosis (Ulcerative) Polyneuropathy May be presenting feature Motor-Sensory Axonal Distribution: Symmetric, or Mononeuritis multiplex Systemic features Myalgia [neuromuscular.wustl.edu]
Psychiatrical
- Suggestibility
Access full-color images and more than 90 online-only topics at Expert Consult, as well as EBMs, Suggested Reading, Patient Teaching Guides, and additional algorithms. [books.google.com]
There was no fatiguability/ptosis/opthalmoplegia to suggest myaesthenia gravis. I looked for evidence of a cause… there were (no) features of dermatomyositis, Cushing’s syndrome, acromegaly, thyroid disease, diabetes, CKD, CLD etc. [medicaleducationleeds.com]
Urogenital
- Hematuria
[…] complement C2 deficiency S erositis: pleuritis/pericarditis O ral ulcers A rthritis/synovitis (usually peripheral polyarthritis) P hotosensitivity B lood Dyscrasias: hemolytic anemia, leukopenia, lymphopenia, thrombocytopenia R enal: proteinuria, casts, hematuria [pathologyexpert.com]
Lateral femoral cutaneous (2%) Differential diagnosis Joint disorders due to hemarthrosis HIV Chronic liver disease Idiopathic Thrombocytopenic Purpura 6 Epidemiology: Single patient; 8th decade Onset: Pain; Sensory loss Clinical Systemic Bleeding: Hematuria [neuromuscular.wustl.edu]
Neurologic
- Asthenia
The specific topics covered in Volume 2 are Neuropathic Pain, Cachexia/Anorexia, Asthenia, and Psychological Issues in the Caregiver. [books.google.com]
“Asthenia” was reported in a patient with bronchopulmonary carcinoid related Cushing’s syndrome ( 11 ) and complete resolution of the Cushing’s syndrome was reported after surgical resection of bronchopulmonary carcinoids ( 11, 14 ). [jtd.amegroups.com]
Workup
Consultations In patients with chronic weakness, consultation with a neurologist may be indicated for electromyography (EMG), further workup, and initiation of pharmacotherapy. [emedicine.medscape.com]
Treatment
Myelopathy Treatment Myelopathy treatment depends on the causes of myelopathy. [hopkinsmedicine.org]
Initial treatment should be aimed at the neoplasm because weakness frequently improves with effective cancer therapy. No further LEMS treatment may be necessary in some patients. [emedicine.medscape.com]
[ edit ] Molecular structure of 3,4-diaminopyridine, a commonly used drug treatment for LEMS If LEMS is caused by an underlying cancer, treatment of the cancer usually leads to resolution of the symptoms. [3] Treatment usually consists of chemotherapy [en.wikipedia.org]
2° Endoneurial lymphoma not reached by treatment Clinical Cranial nerves Nerves Often single cranial nerve Common: III; V; VI; VII ; Mental nerve Rare: Optic nerve & chiasm; Trigeminal; Glossopharyngeal; Acoustic Syndromes: Anatomic Orbital: Frontal headache [neuromuscular.wustl.edu]
Prognosis
[…] macroglobulinemia (WM)/Lymphoplasmocytic lymphoma (LPL) Mantle Cell Hodgkin (10%) Epidemiology: Younger patients Clinical Spread: Less likely to be extra-nodal than NHL Associated polyneuropathies Demyelinating Drug-induced ( Checkpoint inhibitors ) Prognosis [neuromuscular.wustl.edu]
The prognosis varies, depending on the degree of the neuronal lesions ( 20 ). [jtd.amegroups.com]
[…] also bind to calcium channels in the cancer cells, and it is presumed that the antibodies originally develop as a reaction to these cells. [3] It has been suggested that the immune reaction to the cancer cells suppresses their growth and improves the prognosis [en.wikipedia.org]
Considering the rapid course and poor prognosis of LC, repeated lumbar puncture and MRI seem to be less invasive than biopsy of IAC region [ 13 ]. [omicsonline.org]
Etiology
Applicable To Carcinomatous neuromyopathy Sensorial paraneoplastic neuropathy [Denny Brown] Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
Diabetes and alcoholism are the most common etiologies of peripheral neuropathy in adults living in developed countries. [aafp.org]
Epidemiology
Mononeuritis Multiplex Lymphoma 5 Lymphoma Features Epidemiology: Most common in industrialized countries Lymphoma Types Non-Hodgkin type (NHL) (90%) Defined by lymphocyte characteristics B-cells (85%): Associated polyneuropathies Aggressive Type: Diffuse [neuromuscular.wustl.edu]
The book also provides updated epidemiologic and statistical data throughout and includes a section on biostatistics in physical medicine and rehabilitation. [books.google.com]
In a previous large scale epidemiological study (United States-based databases, 1973-1991, 8,305 cases) metastases were evident at diagnosis in 45% of patients, and the overall 5-year survival was 50% ( 5 ). [jtd.amegroups.com]
Pathophysiology
Motor denervation pathophysiology Heirarchical Major Groups Muscle disorders Drugs Steroid myopathy Drug induced Myopathy Poisoning (Specific Agent) Alcohol myopathy Organ Poisoning (Intoxication) Drug induced Neuromuscular junct/block Risks: Mild discomfort [medchrome.com]
Pathophysiology Although peripheral neuropathy has multiple etiologies, the nerve has a limited number of ways to respond to injury. 4, 5 The damage can occur at the level of the axon (i.e., axonopathy). [aafp.org]
Pinealoma Para Myokymia of the superior oblique muscle (typically with brief episodic ocular movements that cause subjective visual shimmering, ocular trembling, and/or tilted vision) Entrapment of the trochlear nerve by a vascular loop (similar to the pathophysiology [merckmanuals.com]
A case of finger clubbing associated with nasopharyngeal carcinoma in a young girl, and review of pathophysiology. J Pak Med Assoc 2009; 59(4): 253-4. [ PubMed ] 29. Garganese MC, et al. [medical.nikkeibp.co.jp]
Prevention
Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]
Treatment and prevention of disability require comprehensive and multidisciplinary approaches. These approaches are frequently long-term, spanning several life stages. [jpgmonline.com]
Luke's international hospital Jan 1989 - Dec 1992 Neurology, Yokohama city hospital Oct 1988 - Dec 1988 Clinical fellow, Neurology and ALS research center, Pacific medical center Published Papers Plain Text 1 2 > Preventive effect of nutrition support [researchmap.jp]