The first two cases presented classically while the third case came with an unusual presentation. Cardiac beriberi is an old disease in modern Bangkok which can present in as several different clinical patterns. [ncbi.nlm.nih.gov]

Mean age of presentation was 3.9 months and mean duration of illness was 7.5 days. All of them presented with tachypnea, chest indrawing and tachycardia. [academic.oup.com]

A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories. [books.google.de]

• Weakness

  History and etymology Beriberi derives from the Sinhalese for "weak, weak", a deliberate duplication of the same word to emphasize how poorly a patient with the condition feels 2. [radiopaedia.org]

  If the deficiency continues, there is damage to the peripheral nerves that causes loss of sensation and muscle weakness, which is called peripheral neuropathy. The legs are most affected. [medical-dictionary.thefreedictionary.com]

  Because alcohol is high in carbohydrate content but deficient in thiamine, some alcoholics become thiamine deficient and weakness of the heart muscle may occur. [wikidoc.org]

  Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. [fpnotebook.com]

  The word 'beri' means weak in Sinhala, a language from Sri Lanka. Beriberi means very weak. [patient.info]

• Malnutrition

  2018, 161 CrossRef 2 Derrick Lonsdale, Chandler Marrs, Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition, 2017, 263 CrossRef 3 Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition, 2017, xi CrossRef 4 Tomoki [onlinelibrary.wiley.com]

  In industrial countries, not only alcoholics, but also deprived people with malnutrition, elderly patients and patients with AIDS are at risk of thiamine deficiency. [ncbi.nlm.nih.gov]

  FEX: Thiamine content of F-75 for complicated severe acute malnutrition: time for a change? Summary of research1 Location: Global What we know: Complicated cases of severe acute malnutrition (SAM) are usually severely ill with comorbidities. [ennonline.net]

  Beriberi was a disease of malnutrition caused by the consumption of overmilled rice. [dictionary.cambridge.org]

  Mots-clés Urgences, Hôpital, Béribéri, Avitaminose B, Insuffisance cardiaque, Malnutrition, Mayotte, Océan Indien [bspe.revuesonline.com]

• Congestive Heart Failure

  Thiamin status, diuretic medications, and the management of congestive heart failure. J Am Diet Assoc. 1995;95:541 - 544. Shimon I, Almog S, Vered Z, et al. [wnyurology.com]

  Sica, Domenic A, “Loop diuretic therapy, thiamine balance, and heart failure”, Congestive Heart Failure. 13(4):244-7, 2007 Jul-Aug. Suter, P M. Haller, J. Hany, A. [medicalnewsbulletin.com]

  Moreover, long-term furosemide use may be associated with thiamine deficiency through urinary loss, contributing to cardiac insufficiency in patients with congestive heart failure. [ncbi.nlm.nih.gov]

  Complications may include: Coma Congestive heart failure Death Psychosis Beriberi is extremely rare in the United States. [medlineplus.gov]

• Anorexia

  Definition (MSH) A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. [fpnotebook.com]

  B1 Lack May Spur Anorexia Nervosa. Vitamin B1 (thiamin) deficiency can result in depression, mood swings, and loss of appetite -- symptoms typical of anorexia nervosa. [moyak.com]

  However due to low body stores of this vitamin, as little as two weeks without thiamine in the diet can lead to beriberi. dieting eating disorders anorexia nervosa bulimia nervosa alcoholics chronic illness prolonged TPN GI malabsorptive conditions e.g [radiopaedia.org]

  Differential Diagnosis Alcoholic Fatty Liver Alcoholic Hepatitis Alcoholic Ketoacidosis Alcoholism Anemia Anorexia Nervosa California Encephalitis Campylobacter Infections Cardiogenic Shock Cardiomyopathy, Alcoholic Cardiomyopathy, Cocaine Cardiomyopathy [wikidoc.org]

  Thiamin deficiency may result from A deficiency of thiamin in the diet Young adults with severe anorexia and people whose diet consists mainly of highly processed carbohydrates (such as polished white rice, white flour, and white sugar) may not consume [merckmanuals.com]

• Weight Loss

  Definition (MSH) A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. [fpnotebook.com]

  Sign and Symptoms Symptoms of beriberi include weight loss, emotional disturbances, impaired sensory perception, weakness and pain in the limbs, and periods of irregular heart rate. Edema is common. [flipper.diff.org]

  Signs and symptoms Symptoms of beriberi include weight loss, emotional disturbances, impaired sensory perception, weakness and pain in the limbs, and periods of irregular heart rate. Edema (swelling of bodily tissues) is common. [ipfs.io]

  They include fatigue, irritability, poor memory, loss of appetite, sleep disturbances, abdominal discomfort, and weight loss. Eventually, a severe thiamin deficiency (beriberi) may develop, characterized by nerve, heart, and brain abnormalities. [merckmanuals.com]

  Symptoms are fatigue, diarrhea, appetite and weight loss, disturbed nerve function causing paralysis and wasting of limbs, edema, and heart failure. [medical-dictionary.thefreedictionary.com]

• Pleural Effusion

  Chest X-ray Chest x-ray usually shows congestion of the lungs with pleural effusions. Treatment Treatment including administration of 100 mg of IV thiamine, then 25 mg daily for about 2 weeks causes dramatic improvement. [wikidoc.org]

  Her chest X-ray showed cardiomegaly with mild pulmonary congestion and pleural effusion ( Fig. 2 ). [synapse.koreamed.org]

  Large left pleural effusion was also present. A mobile mass was also attached to the non-coronary cusp of aortic valve, and was thought to be a fibroelastoma. EKG tracing demonstrated atrial fibrillation with Left Bundle Branch Block pattern. [medicalnewsbulletin.com]

  Chest computed tomography showed bilateral pleural effusion with left lung atelectasis. [journals.lww.com]

• Common Cold

  Recently, large-scale scientific studies have cast doubt over how much vitamin C supplements protect people against the common cold. Many of the studies in their review asked whether vitamin C reduces the incidence of the common cold. [ufrgs.br]

• Diarrhea

  Extended periods of diarrhea or chronic liver disease can result in the body's inability to maintain normal levels of many nutrients, including thiamine. [medical-dictionary.thefreedictionary.com]

  […] it hard for your body to absorb and store thiamine genetic beriberi, a rare condition that prevents the body from absorbing thiamine hyperthyroidism (overactive thyroid gland) extreme nausea and vomiting in pregnancy bariatric surgery AIDS prolonged diarrhea [healthline.com]

  […] an overactive thyroid gland ( hyperthyroidism ), pregnancy, breastfeeding, strenuous exercise, and fever Disorders that interfere with the metabolism of the vitamin, such as liver disorders Disorders that prevent thiamin from being absorbed, such as diarrhea [merckmanuals.com]

  […] following symptoms may be described in infantile beriberi: Hoarseness, where the child makes moves to moan but emits no sound or just faint moans, caused by nerve paralysis Weight loss, becoming thinner and then marasmic as the disease progresses Vomiting Diarrhea [flipper.diff.org]

• Loss of Appetite

  General symptoms include loss of appetite and overall lassitude, digestive irregularities, and a feeling of numbness and weakness in the limbs and extremities. (The term beriberi is derived from the Sinhalese word meaning “extreme weakness.”) [britannica.com]

  They include fatigue, irritability, poor memory, loss of appetite, sleep disturbances, abdominal discomfort, and weight loss. Eventually, a severe thiamin deficiency (beriberi) may develop, characterized by nerve, heart, and brain abnormalities. [merckmanuals.com]

  There is a loss of appetite, indigestion, severe constipation, and a lack of hydrochloric acid in the stomach. Nervous System. Glucose is essential for the central nervous system to function normally. [encyclopedia.com]

  Vitamin B1 (thiamin) deficiency can result in depression, mood swings, and loss of appetite -- symptoms typical of anorexia nervosa. [moyak.com]

  Symptoms are fatigue, diarrhea, appetite and weight loss, disturbed nerve function causing paralysis and wasting of limbs, edema, and heart failure. [medical-dictionary.thefreedictionary.com]

• Heart Disease

  The heart becomes dilated and progresses to heart failure. Beriberi heart disease may cause sudden cardiac dysfunction within days of onset of symptoms. [wikidoc.org]

  The cases cover a spectrum of beriberi heart disease ranging from a hyperdynamic circulation to circulatory shock. [ncbi.nlm.nih.gov]

  And for a majority of heart disease patients, beriberi (B vitamin deficiency) of the heart is the underlying cause of the disease. [spineboy.com]

  Benchimol AB, Schlesinger P (1953) Beri beri heart disease. Am Heart J 46:245–263 Google Scholar 7. [link.springer.com]

• Tachycardia

  All of them presented with tachypnea, chest indrawing and tachycardia. [academic.oup.com]

  Shoshin beriberi is characterized by hypotension, tachycardia, and lactic acidosis and is mainly encountered in non-alcoholic patients in Asian countries, although it has also been seen in alcoholics in Western countries. [ncbi.nlm.nih.gov]

• Muscle Weakness

  Abstract Beriberi (BB), thiamine deficiency, has been described in the Asian literature in the 17th century and is characterized by peripheral neuropathy and muscle weakness, also called "dry" beriberi (BB) to differentiate it from "wet" BB, with essentially [ncbi.nlm.nih.gov]

  If the deficiency continues, there is damage to the peripheral nerves that causes loss of sensation and muscle weakness, which is called peripheral neuropathy. The legs are most affected. [encyclopedia.com]

  The ankle and then the knee reflexes are lost and the patients have muscle weakness starting with the foot. [ennonline.net]

• Muscular Atrophy

  atrophy, paresthesias, abdominal pain and if extreme, ↑ intracranial pressure and coma. [medical-dictionary.thefreedictionary.com]

• Anger

  Seite 147 - DV, Angerer, LM, and Angerer, RC (1984) Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev. Biol. 101, 485-502. ‎ [books.google.de]

  Pagina 147 - DV, Angerer, LM, and Angerer, RC (1984) Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev. Biol. 101, 485-502. ‎ [books.google.ro]

• Delusion

  People with later stages of beriberi will show memory loss, confusion, or delusions. A physical exam will alert your doctor to any heart problems. Rapid heartbeat, swelling of the lower legs, and difficulty breathing are all symptoms of beriberi. [healthline.com]

  […] signs of congestive heart failure, including: Difficulty breathing with neck veins that stick out Enlarged heart Fluid in the lungs Rapid heartbeat Swelling in both lower legs A person with late-stage beriberi may be confused or have memory loss and delusions [medlineplus.gov]

• Irritability

  There is severe fatigue, loss of memory, irritability, insomnia, burning pain in the feet, foot drop, confusion and paralysis. [medical-dictionary.thefreedictionary.com]

  Definition (MSH) A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. [fpnotebook.com]

  At first, people have vague symptoms such as fatigue and irritability, but a severe deficiency (beriberi) can affect the nerves, muscles, heart, and brain. The diagnosis is based on symptoms and a favorable response to thiamin supplements. [merckmanuals.com]

  Fibromyalgia symptoms overlap with those of irritable bowel syndrome, temporomandibular join (TMJ) disorder and chronic low back pain. Conventional treatment is disappointing. [lewrockwell.com]

  Diabetic Ketoacidosis Encephalopathy, Dialysis Encephalopathy, Hepatic Encephalopathy, Hypertensive Encephalopathy, Uremic Enterobacter Infections Enteroviruses Folic Acid Deficiency Goiter Goiter, Diffuse Toxic Hepatic Failure Hyperthyroidism Ileus Irritable [wikidoc.org]

• Peripheral Neuropathy

  Neurological examination revealed peripheral neuropathy in the lower legs and cognitive alteration. [ncbi.nlm.nih.gov]

  Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. [fpnotebook.com]

  Thiamine deficiency leads to one of two clinical conditions - dry beriberi in which a peripheral neuropathy predominates and wet beriberi which presents with cardiac failure. [dictionary.cambridge.org]

  The clinical disease, beri-beri, is divided into a “wet” form, which causes congestive heart failure, and a “dry” form, which causes neurologic disease in the form of peripheral neuropathy and Wernicke-Korsakoff syndrome. beri-beri Nutrition A disease [medical-dictionary.thefreedictionary.com]

  If the deficiency continues, there is damage to the peripheral nerves that causes loss of sensation and muscle weakness, which is called peripheral neuropathy. The legs are most affected. [encyclopedia.com]

• Headache

  Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. [fpnotebook.com]

  Monroe noted that fibromyalgia has many similarities with thiamin deficiency, such as muscle tenderness, frequent headaches, sleep disturbances, fatigue. In developed countries, alcohol consumption explains most of the cases of thiamin deficiency. [lewrockwell.com]

(See Pathophysiology, Etiology, Presentation, and Workup.) [6, 7] Dietary thiamine Food that are rich in thiamine are as follows [1] (see Table 1, below): Whole-grain foods Meat/fish/poultry/eggs Milk and milk products Vegetables (ie, green, leafy vegetables [emedicine.medscape.com]

• Mycobacterium Avium Complex

  Seite 370 - Recommendations on prophylaxis and therapy for disseminated Mycobacterium avium complex disease in patients infected with the human immunodeficiency virus. ‎ [books.google.de]

  Pagina 370 - Recommendations on prophylaxis and therapy for disseminated Mycobacterium avium complex disease in patients infected with the human immunodeficiency virus. ‎ [books.google.ro]

• Pleural Effusion

  Chest X-ray Chest x-ray usually shows congestion of the lungs with pleural effusions. Treatment Treatment including administration of 100 mg of IV thiamine, then 25 mg daily for about 2 weeks causes dramatic improvement. [wikidoc.org]

  Her chest X-ray showed cardiomegaly with mild pulmonary congestion and pleural effusion ( Fig. 2 ). [synapse.koreamed.org]

  Large left pleural effusion was also present. A mobile mass was also attached to the non-coronary cusp of aortic valve, and was thought to be a fibroelastoma. EKG tracing demonstrated atrial fibrillation with Left Bundle Branch Block pattern. [medicalnewsbulletin.com]

  Chest computed tomography showed bilateral pleural effusion with left lung atelectasis. [journals.lww.com]

Treatment Treatment including administration of 100 mg of IV thiamine, then 25 mg daily for about 2 weeks causes dramatic improvement. [wikidoc.org]

Treatments & Home Remedies for Beriberi Medical Treatments For the treatment of beriberi, doctors generally prescribe thiamine shots or pills. [organicfacts.net]

[…] of thiamine deficiency thiamine 100 mg orally daily Prevention and treatment of thiamine deficiency in severe alcoholics thiamine 100 to 200 mg IV daily for 3 days then thiamine 100 mg orally daily Treatment of Wernicke encephalopathy thiamine 500 mg [lifeinthefastlane.com]

Treatment Treatment with thiamine reverses the deficiency in the body and relieves most of the symptoms. [encyclopedia.com]

Blood tests may be repeated after the treatment is started. These tests will show how well you are responding to the medicine. Untreated, beriberi can be fatal. With treatment, symptoms usually improve quickly. Heart damage is usually reversible. [medlineplus.gov]

Treatment and prognosis Optimal treatment of beriberi relies upon a two-pronged approach: thiamine supplementation supportive therapies e.g. cardiac support Recovery is often rapid once thiamine supplements are started. [radiopaedia.org]

Prognosis The prognosis for beriberi is usually good, unless patients have established Korsakoff syndrome. When patients have progressed to this stage, the degree of damage is only minimally reversible. [namrata.co]

If treated early the prognosis of beriberi is good prognosis but mortality still ranges between 10 and 20%. Despite early initiation of treatment, complete remission is rare as cognitive changes are not reversible in most cases [ 20 ]. [karger.com]

Prognosis Mortality is rare and is usually associated with the wet form due to cardiac failure. [ 26 ] Morbidity is also rare and usually presents in the dry form with neurological symptoms. [patient.info]

In lactic acidosis and/or hyperdynamic circulation without any other apparent etiology in patients with possible vitamin B1 deficiency, the diagnosis of BB must be considered and thiamine should be administered. [ncbi.nlm.nih.gov]

In the study of the etiology of cardiovascular dysfunctions in general and of heart disease in particular, attention has been focused mainly on infectious and degenerative processes and on congenital malformations. [jamanetwork.com]

Etiology In general, those individuals with a poor diet are most likely to develop thiamine deficiency. [radiopaedia.org]

The nature of the disorder, certain symptoms of which started in infancy, was such that it strongly indicated a metabolic rather than a nutritional etiology, involving energy metabolism. [link.springer.com]

Importantly, we reviewed the literature on wet beriberi and summarized the etiology, reports of cardiac output (CO) and systemic vascular resistance (SVR), currently available diagnostic tests, and thiamine use in patients with wet beriberi. [journals.lww.com]

It is caused by severe thiamine deficiency. [1] Epidemiology and Demographics This disease is most prevalent in the Far East, however, in the past decade its prevalence has markedly decreased. [wikidoc.org]

[…] concurrently, including Wernicke's encephalopathy (mainly affecting the central nervous system), Korsakoff's syndrome (amnesia with additional psychiatric manifestations), and Wernicke-Korsakoff syndrome (with both neurologic and psychiatric symptoms) Epidemiology [flipper.diff.org]

Methods: By means of systematic literature review, epidemiological data, clinical characteristics and diagnostic as well as therapeutic recommendations for bariatric beriberi were elicited. [karger.com]

Another translation is 'I cannot, I cannot'. [ 2 ] Epidemiology Beriberi was endemic in some areas of the world and may be related to the consumption of milled rice. [patient.info]

The disease is also common in fad diet appliers. [2] Pathophysiology Pathologically the heart in cardiac beriberi is most often hypertrophied and dilated, with involvement of both the right and left chambers. [wikidoc.org]

Pathophysiology Thiamine in the human body has a half-life of 18 days and is quickly exhausted, particularly when metabolic demands exceed intake. [flipper.diff.org]

(See Pathophysiology, Etiology, Presentation, and Workup.) [6, 7] Dietary thiamine Food that are rich in thiamine are as follows [1] (see Table 1, below): Whole-grain foods Meat/fish/poultry/eggs Milk and milk products Vegetables (ie, green, leafy vegetables [emedicine.medscape.com]

Attas M, Hanley HG, Stultz D (1978) Fulminant beri beri heart disease with lactic acidosis: presentation of a case with evaluation of left ventricular function and review of pathophysiologic mechanisms. Circulation 58:566–572 Google Scholar 4. [link.springer.com]

Also known as aneurin, this vitamin helps prevent neuritic and beriberi. B1 vitamin benefits include prevention of severe eye fatigue and neurodegeneration. [newsmax.com]

In 2014, Save The Children commissioned Burnet to carry out a technical review of the evidence for the prevention of infantile beriberi to stimulate discussion and to advocate for prevention strategies in Lao PDR. [burnet.edu.au]

Article navigation 1From the Divisions for Heart Disease and Stroke Prevention (BAB) and Reproductive Health (WDB), National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA; and the Nutritional Biomarkers Branch, Division of Laboratory [ajcn.nutrition.org]

Thiamine before glucose to prevent Wernicke encephalopathy: examining the conventional wisdom. JAMA. 1998 Feb 25;279(8):583-4. [lifeinthefastlane.com]

A healthy diet that is rich in rice can always help you prevent beriberi. Rice Bran This is the best-known remedy for beriberi and has been practiced for hundreds of years. [organicfacts.net]