The first two cases presented classically while the third case came with an unusual presentation. Cardiac beriberi is an old disease in modern Bangkok which can present in as several different clinical patterns. [ncbi.nlm.nih.gov]

Mean age of presentation was 3.9 months and mean duration of illness was 7.5 days. All of them presented with tachypnea, chest indrawing and tachycardia. [academic.oup.com]

• Malnutrition

  In industrial countries, not only alcoholics, but also deprived people with malnutrition, elderly patients and patients with AIDS are at risk of thiamine deficiency. [ncbi.nlm.nih.gov]

  2018, 161 CrossRef 2 Derrick Lonsdale, Chandler Marrs, Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition, 2017, 263 CrossRef 3 Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition, 2017, xi CrossRef 4 Tomoki [onlinelibrary.wiley.com]

  FEX: Thiamine content of F-75 for complicated severe acute malnutrition: time for a change? Summary of research1 Location: Global What we know: Complicated cases of severe acute malnutrition (SAM) are usually severely ill with comorbidities. [ennonline.net]

  Beriberi was a disease of malnutrition caused by the consumption of overmilled rice. [dictionary.cambridge.org]

• Congestive Heart Failure

  Moreover, long-term furosemide use may be associated with thiamine deficiency through urinary loss, contributing to cardiac insufficiency in patients with congestive heart failure. [ncbi.nlm.nih.gov]

  On initial examination; the patient was in respiratory distress clinically, secondary to congestive heart failure, with peripheral edema and tachycardia. [medicalnewsbulletin.com]

  Patients present with an enlarged heart, tachycardia, high-output congestive heart failure, peripheral edema, and peripheral neuritis. [jdrntruhs.org]

  The clinical disease, beri-beri, is divided into a “wet” form, which causes congestive heart failure, and a “dry” form, which causes neurologic disease in the form of peripheral neuropathy and Wernicke-Korsakoff syndrome. beri-beri Nutrition A disease [medical-dictionary.thefreedictionary.com]

  Complications may include: Coma Congestive heart failure Death Psychosis Beriberi is extremely rare in the United States. [medlineplus.gov]

• Prisoner of War

  A case is described of an Englishman who suffered severe 'wet beriberi' whilst a prisoner of war (POW) of the Japanese in World War II. 2. [ncbi.nlm.nih.gov]

  A case is described of an Englishman who suffered severe ‘wet beriberi’ whilst a prisoner of war (POW) of the Japanese in World War II. 2. [cambridge.org]

• Hypoxemia

  However, 5 days after the shock, hypoxemia and diffuse radiographic infiltrates progressed, and a diagnosis of adult respiratory distress syndrome (ARDS) was made. After the occurrence of an air leak, the patient died of respiratory failure. [ncbi.nlm.nih.gov]

• Regurgitation

  LV: left ventricule, MR: mitral regurgitation, TR: tricuspid regurgitation. Cardiac magnetic resonance imaging. This shows left ventricular dilatation without delayed enhancement, confirming dilated CMP and excluding ischemic CMP. [synapse.koreamed.org]

  The 2D-echocardiography revealed right atrial and ventricular dilatation with tricuspid regurgitation, pulmonary hypertension and good myocardial contractility [ 5 ], while ECG changes were non-specific and non-contributory. [academic.oup.com]

  Blood thiamine level was Two-dimensional (2D) echocardiogram [Figure 2] revealed normal valves with moderate tricuspid regurgitation, moderate pulmonary artery hypertension, dilated right atrium and right ventricle, with intact septa, no vegetation, no [jdrntruhs.org]

• Tachycardia

  Majority presented with tachypnea, chest indrawing and tachycardia and cardiomegaly with dilatation of right heart and pulmonary hypertension on 2D-echocardiography. [ncbi.nlm.nih.gov]

  All of them presented with tachypnea, chest indrawing and tachycardia. [academic.oup.com]

• Heart Disease

  The cases cover a spectrum of beriberi heart disease ranging from a hyperdynamic circulation to circulatory shock. [ncbi.nlm.nih.gov]

  Beriberi heart disease in Durban. A retrospective study. S Afr Med J 1987;72:241–244. [synapse.koreamed.org]

  She developed hyponatremia and beriberi heart disease, which resulted in metabolic acidosis and cardiogenic shock (shoshin beriberi). Mechanical ventilation was applied for pulmonary edema. [onlinelibrary.wiley.com]

  Beriberi heart disease may cause sudden cardiac dysfunction within days of onset of symptoms. [wikidoc.org]

• Femoral Bruit

  A notable finding was that even in the presence of peripheral circulatory shock, patients with beriberi had preservation of the femoral pulses often with 'pistol shots' and femoral bruit; this finding has clinical value in the diagnosis of acute cardiovascular [ncbi.nlm.nih.gov]

• Pansystolic Murmur

  Cardiovascular system examination revealed a third heart sound along with first and second heart sounds, and a grade 3/6 pansystolic murmur was heard all over precordium. [jdrntruhs.org]

• Impulsivity

  […] examination revealed pulse rate was 100/min, regular high volume, collapsing and pistol shot sounds were heard over large arteries, blood pressure was 80/10 mm of Hg, temperature was 100 F, jugular venous pressure was elevated with prominent "V" wave, apical impulse [jdrntruhs.org]

(See Pathophysiology, Etiology, Presentation, and Workup.) [6, 7] Dietary thiamine Food that are rich in thiamine are as follows [1] (see Table 1, below): Whole-grain foods Meat/fish/poultry/eggs Milk and milk products Vegetables (ie, green, leafy vegetables [emedicine.medscape.com]

• Mycobacterium Avium Complex

  Pagina 370 - Recommendations on prophylaxis and therapy for disseminated Mycobacterium avium complex disease in patients infected with the human immunodeficiency virus. ‎ [books.google.ro]

  Seite 370 - Recommendations on prophylaxis and therapy for disseminated Mycobacterium avium complex disease in patients infected with the human immunodeficiency virus. ‎ [books.google.de]

• Prominent A-Wave

  "V" wave, apical impulse was felt in sixth intercostal space. [jdrntruhs.org]

• Prominent V-Waves

  "V" wave, apical impulse was felt in sixth intercostal space. [jdrntruhs.org]

Treatment consists of thiamine administration with rapid clinical improvement after supplementation. [ncbi.nlm.nih.gov]

We herein present one case of cardiac beriberi in which optimal and timely treatment induced dramatic improvement in left ventricular (LV) systolic function. [synapse.koreamed.org]

The disorder is a metabolic emergency and requires immediate treatment with intravenous thiamine. Sudden cardiac failure is common. Death occurs from right heart failure and the patient usually dies fully conscious. [jdrntruhs.org]

[…] of thiamine deficiency thiamine 100 mg orally daily Prevention and treatment of thiamine deficiency in severe alcoholics thiamine 100 to 200 mg IV daily for 3 days then thiamine 100 mg orally daily Treatment of Wernicke encephalopathy thiamine 500 mg [lifeinthefastlane.com]

Treatments & Home Remedies for Beriberi Medical Treatments For the treatment of beriberi, doctors generally prescribe thiamine shots or pills. [organicfacts.net]

Treatment and prognosis Optimal treatment of beriberi relies upon a two-pronged approach: thiamine supplementation supportive therapies e.g. cardiac support Recovery is often rapid once thiamine supplements are started. [radiopaedia.org]

Prognosis The prognosis for beriberi is usually good, unless patients have established Korsakoff syndrome. When patients have progressed to this stage, the degree of damage is only minimally reversible. [namrata.co]

If treated early the prognosis of beriberi is good prognosis but mortality still ranges between 10 and 20%. Despite early initiation of treatment, complete remission is rare as cognitive changes are not reversible in most cases [ 20 ]. [karger.com]

Prognosis Mortality is rare and is usually associated with the wet form due to cardiac failure. [ 26 ] Morbidity is also rare and usually presents in the dry form with neurological symptoms. [patient.info]

The nature of the disorder, certain symptoms of which started in infancy, was such that it strongly indicated a metabolic rather than a nutritional etiology, involving energy metabolism. [link.springer.com]

Any factor leading to an increased thiamine demand may be etiological. For example, young men are often affected possibly because they work hardest. [jdrntruhs.org]

In lactic acidosis and/or hyperdynamic circulation without any other apparent etiology in patients with possible vitamin B1 deficiency, the diagnosis of BB must be considered and thiamine should be administered. [ncbi.nlm.nih.gov]

In the study of the etiology of cardiovascular dysfunctions in general and of heart disease in particular, attention has been focused mainly on infectious and degenerative processes and on congenital malformations. [jamanetwork.com]

Etiology In general, those individuals with a poor diet are most likely to develop thiamine deficiency. [radiopaedia.org]

It is caused by severe thiamine deficiency. [1] Epidemiology and Demographics This disease is most prevalent in the Far East, however, in the past decade its prevalence has markedly decreased. [wikidoc.org]

[…] concurrently, including Wernicke's encephalopathy (mainly affecting the central nervous system), Korsakoff's syndrome (amnesia with additional psychiatric manifestations), and Wernicke-Korsakoff syndrome (with both neurologic and psychiatric symptoms) Epidemiology [flipper.diff.org]

Methods: By means of systematic literature review, epidemiological data, clinical characteristics and diagnostic as well as therapeutic recommendations for bariatric beriberi were elicited. [karger.com]

Another translation is 'I cannot, I cannot'. [ 2 ] Epidemiology Beriberi was endemic in some areas of the world and may be related to the consumption of milled rice. [patient.info]

The disease is also common in fad diet appliers. [2] Pathophysiology Pathologically the heart in cardiac beriberi is most often hypertrophied and dilated, with involvement of both the right and left chambers. [wikidoc.org]

Pathophysiology Thiamine in the human body has a half-life of 18 days and is quickly exhausted, particularly when metabolic demands exceed intake. [flipper.diff.org]

(See Pathophysiology, Etiology, Presentation, and Workup.) [6, 7] Dietary thiamine Food that are rich in thiamine are as follows [1] (see Table 1, below): Whole-grain foods Meat/fish/poultry/eggs Milk and milk products Vegetables (ie, green, leafy vegetables [emedicine.medscape.com]

Attas M, Hanley HG, Stultz D (1978) Fulminant beri beri heart disease with lactic acidosis: presentation of a case with evaluation of left ventricular function and review of pathophysiologic mechanisms. Circulation 58:566–572 Google Scholar 4. [link.springer.com]

Also known as aneurin, this vitamin helps prevent neuritic and beriberi. B1 vitamin benefits include prevention of severe eye fatigue and neurodegeneration. [newsmax.com]

In 2014, Save The Children commissioned Burnet to carry out a technical review of the evidence for the prevention of infantile beriberi to stimulate discussion and to advocate for prevention strategies in Lao PDR. [burnet.edu.au]

Article navigation 1From the Divisions for Heart Disease and Stroke Prevention (BAB) and Reproductive Health (WDB), National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA; and the Nutritional Biomarkers Branch, Division of Laboratory [ajcn.nutrition.org]

Thiamine before glucose to prevent Wernicke encephalopathy: examining the conventional wisdom. JAMA. 1998 Feb 25;279(8):583-4. [lifeinthefastlane.com]

When it comes to preventing beriberi modernus, it's every man for himself. Such is the current state of disease prevention in America today. The Best of Bill Sardi The Best of Bill Sardi [lewrockwell.com]