The first case was a 36-year-old gentleman who presented with 6 months history of painless swelling on the left side of neck. [ncbi.nlm.nih.gov]

• Hypoventilation

  PATIENTS AND METHODS: We report the case of a patient with obesity hypoventilation syndrome (OHS) in whom OSAS caused by a carotid body paraganglioma contributed to recurrent bouts of severe alveolar hypoventilation. [ncbi.nlm.nih.gov]

• Carotid Bruit

  Very rarely a carotid bruit can be heard, due to an important compression induced by the tumor on the carotid arteries. [romanianjournalcardiology.ro]

• Tinnitus

  Summary A 48-year-old hypertensive and diabetic patient presented with a 10-year history of progressive right facial pain, tinnitus, hearing loss, sweating, and palpitations. [edmcasereports.com]

  Cranial nerve palsies can occur and include dysphagia, hoarseness, and tinnitus. Rarely, a carotid body tumor may contain neurosecretory granules, which cause symptoms such as palpitations, headaches, diaphoresis, dizziness, and flushing. [evtoday.com]

  It is pathognomonic for this tumour but it usually follows a year after the initial symptoms of hearing loss and pulsatile tinnitus. [patient.info]

  When significant involvement is present then the lesion may cause pulsatile tinnitus and hearing loss. Additionally, a number of patterns of cranial nerve palsies have been described due to the involvement of the nerves at the jugular foramen. [radiopaedia.org]

• Neck Swelling

  We describe detection of one such tumor by fine needle aspiration cytology in a 30-year-old lady with left neck swellings clinically suspected of tubercular lymphadenitis. [pacificejournals.com]

  Five (11.35%) had a history of hypertension and (9.08%) had a history of neck swelling in the family. Pain was associated feature in nine (20.43%) of patients. [indjvascsurg.org]

  A middle-aged male patient presenting with a neck swelling was diagnosed with a glomus vagale tumor on USG by the direct demonstration of its continuity with the vagus nerve, and Doppler examination confirmed its vascularity. [ncbi.nlm.nih.gov]

• Headache

  She did admit to occasional headaches, episodes of sweating, tremors, and a throbbing sensation in the head. An increase in labetalol and nifedipine improved hypertension control and she was discharged with plan for surgery. [omicsonline.org]

  Rarely, a carotid body tumor may contain neurosecretory granules, which cause symptoms such as palpitations, headaches, diaphoresis, dizziness, and flushing. [evtoday.com]

  Lateral carotid arteriogram obtained 22 years after radiation therapy in a 20-year-old woman who presented in June 1970 with episodic hypertension, headaches, and palpitations. [emedicine.medscape.com]

• Temporal Headache

  Case Report: A 58-year-old African American lady, presented to the emergency room for sudden onset of right eye blindness and left eye blurry vision, associated with a 2 day history of a temporal headache. She was noted to be in hypertensive crisis. [omicsonline.org]

This case report describes two patients with this rare tumour with diagnostic workup and treatment options. The first case was a 36-year-old gentleman who presented with 6 months history of painless swelling on the left side of neck. [ncbi.nlm.nih.gov]

Objective: Here we present the case of a fatal norepinephrine secreting carotid body paraganglioma diagnosed incidentally during workup for a suspected stroke. [omicsonline.org]

The patients were subjected to routine and specialized workup. [indjvascsurg.org]

Surgical treatment of carotid body paragangliomas is a challenge to the surgeon because of the large vascularization of the tumor, involvement of the carotid vessels and the close anatomical relationship with the cranial nerves. [ncbi.nlm.nih.gov]

Treatment After careful explanation, the patient and her family consented to a therapeutic trial of octreotide. [edmcasereports.com]

Treatment and prognosis Surgical excision is the treatment of choice. The larger the tumor the higher the risk of operative complications 2. In patients for whom the risk of complications precludes surgery, radiotherapy may be considered 1-2. [radiopaedia.org]

Updated and new perspectives on diagnosis, prognosis, and therapy of malignant pheochromocytoma/paraganglioma. [Internet] J Oncol. 2012 [Consultado 2014 11Ene]; 2012: 872713. [revista.acorl.org]

Prognosis Glomus jugulare tumours tend to grow slowly with only a small proportion metastasising. The associated cranial nerve palsies tend to be more cosmetic than debilitating. [patient.info]

Overall prognosis is quite good with complete surgical resection. Continued follow-up is necessary, however, as recurrence and metastasis may occur years later. [adrenaltumors.org]

They have a low incidence (0.6%), are generally benign, have a poorly defined etiology, and multiple factors have been associated with their origin. [ncbi.nlm.nih.gov]

If with most of the authors accepting the tumors' origin to be unknown(7), others believe that its etiology may be related to chronic hypoxia, high altitudes and dominant autosomic transmission with incomplete penetrance(6,7). [arquivosdeorl.org.br]

Interestingly, the male-to-female ratio differs in patients dwelling at high altitudes above 2,000 meters (1:8.3) than those patients dwelling at sea level (1:1.0-1.4). [14] Etiology The only known risk factors are the presence of chronic hypoxic stimulation [emedicine.medscape.com]

01 Aim: The aim of this study is to assess the sensitivity and specificity of procalcitonin to determine bacterial etiology of diarrhea. [science.gov]

Exact etiology of these tumors is not known. Male and female distributions are equal except at high altitude where females appear to predominate. Diagnosis of a chemodectoma usually begins with a color flow duplex scan. [indjvascsurg.org]

Each entity is extensively discussed with information on clinicopathological, epidemiological, immunophenotypic and genetic aspects of these diseases. The book is an authoritative, concise reference, prepared by 150 authors from 20 countries. [books.google.com]

Parry DM, Li FP, Strong LC et al. (1982) Carotid body tumors in humans: genetics and epidemiology. J Natl Cancer Inst 68/4: 573–578 Google Scholar 23. [link.springer.com]

[…] body paraganglioma Jugulotympanic paraganglioma (previously called glomus jugulare tumors) Vagal paraganglioma Laryngeal paraganglioma Chemodectoma refers to carotid and aortic body paraganglioma (tumors of paraganglia with a chemoreceptor function) Epidemiology [pathologyoutlines.com]

Epidemiology Frequency Parasympathetic paragangliomas are rare, with a prevalence of 1-2 per 100,000 population. [7] Carotid body tumors (CBTs) constitute about 65% of head and neck paragangliomas. [emedicine.medscape.com]

Pathophysiology Carotid body tumors (CBTs) are classified into sporadic, familial, and hyperplastic forms. The familial paraganglioma form is a genetically heterogenous entity; currently, 4 genes are identified. [emedicine.medscape.com]

Malignant catecholamine-secreting carotid body paragangliomas are best treated by composite resection (internal carotid artery and neck dissection), with special attention being given to measures preventing severe hypertension and arrhythmias in the perioperative [ncbi.nlm.nih.gov]

Timely diagnosis and treatment may have prevented this fatality. Biography : Email: [email protected] [omicsonline.org]

Postoperatively, intensive surveillance with intermittent nasogastric suctioning was done to prevent aspiration or obstruction of airway due to IX, X, and XII cranial nerve dysfunction. [karnatakaanaesthj.org]

Sternocleidomastoid muscle cover was provided to the carotid artery in all the patients to prevent secondary hemorrhage from the carotid artery. [icvts.oxfordjournals.org]

In most cases, it is necessary to tie off or pack the jugular vein in the neck and the mastoid portion of the ear to prevent excessive bleeding at tumor removal. [earsurgery.org]