Presentation
A family (father, daughter and son) with Metachondromatosis is presented, and the tendency to spontaneous remission in this condition is emphasized. A "second thought", when considering the diagnosis of mce, seems worthwhile. [ncbi.nlm.nih.gov]
Pain medication is only used if symptoms of pain present. [physio-pedia.com]
Clinical Presentation Signs/Symptoms: Hard swelling for many years Symptoms dependent on location/size May cause mechanical symptoms from compression of adjacent structures such as tendons, nerve or blood vessels An overlying bursa may form and result [tumorsurgery.org]
They are the most common benign bone lesions and present during late childhood and adolescence. [en.wikibooks.org]
Entire Body System
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Swelling
Case report A 9 yr old boy presented with swelling over chest on the right side. The skin over the swelling was normal. It was painless and non tender and fixed to the rib anteriorly (Fig 1). [jocr.co.in]
Clinical Presentation Signs/Symptoms: Hard swelling for many years Symptoms dependent on location/size May cause mechanical symptoms from compression of adjacent structures such as tendons, nerve or blood vessels An overlying bursa may form and result [tumorsurgery.org]
[…] necrosis opening operation ophthalmy opium osseous pain patient periosteum portion pressure produced protruded puncture removed scrofulous Sir Astley Cooper situation skin sloughing sometimes sore splints stricture substance suppuration surface surgeon swelling [books.google.de]
A painless skeletal swelling or a slowly growing mass is the usual mode of presentation. HME leads to abnormalities such as palpable bony masses and limb shortening in the first or second decade of life. [emedicine.medscape.com]
This will cause immediate pain and swelling in the area of the tumor. Because many osteochondromas do not cause any discomfort or other symptoms, they are often discovered by accident when an x-ray is done for an unrelated reason. [orthoinfo.aaos.org]
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Gaucher Disease
In MHE, the distal femurs develop an “Erlenmeyer flask” shapes, similar to Gaucher’s disease. CT and MRI are also useful to determine the extent of soft tissue impingement surrounding the lesion (Tarassoli, 2009). [posna.org]
Skin
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Excoriation
Diseases of Veins 267 Aneurismal Varix or Venous Aneu 275 Necrosis 283 Mollities 297 Exostoses 304 Inflammation of Synovial Membrane 311 Scrofulous Disease of Joints begin 318 Injuries and Diseases of Tendons 327 Growth of Tumours 333 Ophthalmitis ib Excoriations [books.google.de]
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Chancre
Puncturing the Bladder 7 58 758 Häufige Begriffe und Wortgruppen abscesses adhesive amputation aneurism applied artery attended bandage become Benjamin Brodie bladder bleeding blood body bone bowels cancer cartilage catheter cause cavity cellular tissue chancre [books.google.de]
Musculoskeletal
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Genu Valgum
[…] hemiepiphysis may improve wrist alignment as well as improving supination and pronation; - ulnar lengthening: - Knee Joint in MED: - leg length inequality may require equalization procedures in 50%; - fibular involvement by osteochondroma may cause: genu [wheelessonline.com]
Genu valgum (commonly known as "knock-knees"), ankle valgus, and bowing and shortening of one or both of the forearm bones are common manifestations. [5] Types [ edit ] Buccal exostosis Footballer's ankle (exotosis of the ankle bone) Hereditary multiple [en.wikipedia.org]
[…] real incidence Usually evident early in childhood Clinical Features Great variation in distribution and extent of condition LLD a common feature Genu valgum may also be present Hands involved may grotesque swelling of digits Bowing of long bones also [flinders.edu.au]
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Back Pain
Odontoid malformation atlanto-axial instability Scoliosis and kyphosis develops in late childhood early adolescence Other abnormalities associate (TEV, hernia, myopia cleft palate) (Tarda) Flattened vertebrae and inter vertebral discs Posterior spinal hump Back [flinders.edu.au]
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Knee Pain
Edema in the vastus medialis muscle (arrows) may be due to muscle impingement. 9 Figure 9: 32 year-old male with knee pain which is worse with activity. [radsource.us]
Neurologic
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Neglect
الصفحة 14 - ... most simple affections of this cavity may, by neglect or improper treatment, ultimately become incurable; those on the other, which are considered the most malignant and dangerous from their inception, might, we have no doubt, by timely [books.google.com]
They reasoned that since there was no history of trauma in those two cases, it may be suggested that “a neglected trauma to an immature bone may result in subungual osteochondroma.” [1] Both patients were male at 30 and 15 years of age respectively. [faoj.org]
Workup
With CT scanning, radiation burden in the young may be a disadvantage, particularly when several examinations may be required in the workup of hereditary multiple exostoses (HME) or sarcomatous transformation. [emedicine.medscape.com]
Imaging Studies: Initial workup begins with history and physical examination including a detailed family history, especially in patients with two or more lesions. Radiographic imaging is the next step and can be diagnostic. [posna.org]
Treatment
Nonsurgical Treatment In most cases, treatment consists of careful observation over time. Your doctor may want to take regular x-rays to keep track of any changes in the tumors. [orthoinfo.aaos.org]
Ausgewählte Seiten Titelseite Inhaltsverzeichnis Inhalt ELEMENTARY AND GENERAL subjects 1 Suppuration and Abscesses 32 Treatment of Abscesses 42 Mortification 50 Of Amputation for Mortification 74 Erysipelas 91 Of Furuncular Carbuncular 99 Deformities [books.google.de]
Treatment: objectives and methods Treatment osteochondroma begin with taking a tissue biopsy. The aim of the study is the exclusion of malignant transformation. Treatment plan bone cartilage akolosov individually. [medicalj-center.info]
[…] for continued osteochondroma growth after skeletal maturity (in which case malignancy is suspected); - definitive treatment includes marginal excision of an active exostosis, including the cartilaginous cap & overlying perichondrium; - deep bony base [wheelessonline.com]
Treatment [ edit ] No treatment is required if the diagnosis is not in doubt and if the patient is relatively asymptomatic. However, surgical resection is indicated for persistent irritation from bursitis or for neurovascular compromise. [en.wikibooks.org]
Prognosis
Cartilaginous Exostosis Prognosis This disease does not carry a deadly prognosis. However, the onset of cartilaginous exostosis can lead to serious health complications for the patient. [knowcancer.com]
The prognosis is favorable In most cases, with successful treatment the prognosis is favorable. Relapses usually do not occur. [medicalj-center.info]
The prognosis is usually excellent It is estimated that very small fraction of individuals may have recurrence after surgery (2% recurrence - according to Mayo Clinic). [dovemed.com]
- the cartilaginous cap should not be traumatized during its removal; - prognosis for a solitary exostosis is excellent ( 5% recurrence following marginal excision) Pseudoaneurysm of the popliteal artery with an unusual arteriographic presentation. [wheelessonline.com]
Treatment and prognosis As they represent normal growth of a growth plate in an abnormal direction, they often stop growing with the rest of the skeleton 3. In most instances, no treatment is required. [radiopaedia.org]
Etiology
This happens in approximately 1% of solitay osteochondroma cases [1] [9] [12] and 5-25% in multiple osteochondromas. [1] [13] Etiology The etiology regarding the development of solitary osteochondroma is currently unknown [6]. [physio-pedia.com]
Hereditary Multiple Exostoses: One Center’s Experience and Review of Etiology. Severity of disease and risk of malignant change in hereditary multiple exostoses. A genotype-phenotype study. [wheelessonline.com]
Causes of tumors in most cases are not the exact etiology. Some tumors appear to be due to genetic nature. Tumors are benign or malignant (cancer). Sometimes benign tumors are transformed into malignant ones. [medicalj-center.info]
Etiology: Osteochondromas have been historically viewed as developmental lesions, but there is evidence supporting a neoplastic origin (Biermann, 2002; Murphey, 2000; Porter, 1999). [posna.org]
Epidemiology
Osteochondromas without a stalk are called sessile exostoses. [2] [11] Epidemiology/Etiology Epidemiology Average age of clinical presentation is between 10 and 30. [2] [7] [10] [8] These tumors account for 10%-15% of all bone tumors [3], while representing [physio-pedia.com]
Epidemiology [ edit ] Age: Present before the age of 20 in 80% of cases ( range of age 10–35 years) Sex: There is a 2:1 male to female predominance for the development of solitary osteochondromas. [en.wikibooks.org]
Epidemiology: Osteochondromas are the most common benign tumor of bone accounting for 10% of primary skeletal tumors and 40% of benign bone tumors (Dahlin, 1986). [posna.org]
Epidemiology Affects 2 per 100,000 population. [ 2 ] More frequently found in Caucasians than in other races. Risk factors Inheritance is autosomal dominant, with near-complete penetrance. [patient.info]
Epidemiology data are based on the Netherlands Committee of bone tumors database. Benign Cartilage Tumors Benign cartilage tumors arise primarily in young age groups, with a peek incidence between the second and third decade. [lumc.nl]
Pathophysiology
Pathophysiology [ edit ] Osteochondromas result from the growth of aberrant growth plate with cartilage on the bony surface. As the cartilage grows, it forms a cap over a bony mass that develops by progressive enchondral ossification. [en.wikibooks.org]
PATHOPHYSIOLOGY • Osteochondromas are developmental lesions rather than true neoplasms • These lesions result from the separation of a fragment of epiphyseal growth plate cartilage, which subsequently herniates through the periosteal bone cuff • The mechanism [slideshare.net]
Prevention
Dislocation of the radial head may occur earlier than previously thought, hindering its prevention. [ncbi.nlm.nih.gov]
How to prevent the danger? As a preventive measure to avoid injuries, fractures, to monitor the current of hereditary diseases. Also children predisposed to this disease on hereditary indicators need to undergo an annual rentgenologicheski study. [medicalj-center.info]
Typically, the cartilage cap and the perichondrium (dense connective tissue around the cartilage) are also excised in such cases to prevent lesion recurrence. [knowcancer.com]