Presentation
Isolated extramural tumour deposits Present Apical node involvement Present Venous and small vessel invasion Intramural vein invasion Present Extramural vein invasion Present Small vessel invasion Present Perineural invasion Present Mismatch repair immunohistochemistry [radiopaedia.org]
In a large autopsy series, metastases to the gallbladder were present in 5.8% of patients [8, 9]. Chen et al. reported a case of transverse colon cancer presenting with manifestations of cholecystitis. [hindawi.com]
We report a case of perforated adenocarcinoma of the cecum that presented as an abscess of the thigh. We also present a review of the literature on this subject. [ncbi.nlm.nih.gov]
Session Number: Poster – Poster Presentations Program Number: P188 View Poster Post Views: 2,287 « Return to SAGES 2012 abstract archive [sages.org]
Entire Body System
- Anemia
A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia. A Tc-99m pertechnetate abdominal scan was positive and surgery revealed an adenocarcinoma of the cecum. No Meckel's diverticulum was identified. [ncbi.nlm.nih.gov]
Left: Adenocarcinoma in an 85 year-old man with anemia and occult bleeding. Center: Sessile lesion in an 86 year-old man with anemia but no history of bleeding. [endoatlas.com]
Anemia, however, was related to a better survival, especially in patients with a Dukes' B carcinoma. Clinicopathological staging according to Dukes' is closely related to survival. [onlinelibrary.wiley.com]
Original Articles: PDF Only Abstract Author Information Authors A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia. [journals.lww.com]
- Weight Loss
A 56-year-old male was admitted in the surgical ward with history of loss of appetite, weight loss, malaise, abdominal distention, melena and abdominal pain of 1-month duration. [go.gale.com]
Common presentations of CRC include alterations in bowel habit, weight loss, and lower gastrointestinal bleeding. [hindawi.com]
Patients who have unexplained weight loss are less likely to respond compared to patients without unexplained weight loss, and patients with cancer localized to the cecal/ascending colon were likely to have worse response to bevacizumab treatment. [jcancer.org]
He had a four-month history of abdominal discomfort, namely intermittent abdominal cramping pain of mild to moderate severity in the middle and lower quadrants, and diarrhea with occasional traces of blood, unquantified weight loss and nausea, and without [scielo.mec.pt]
loss Blood in stool Loss of appetite Change in bowel habits Location Rectum (15%), sigmoid (20%), descending colon (10%), transverse colon (12%), ascending colon (8%), cecum (8%) Location seems to be changing and moving back to cecum More common in right [learningradiology.com]
- Pallor
Anemia can lead to fatigue, weakness and pallor. The cecum, a pouchlike structure, lies very close to the appendix. [livestrong.com]
Physical examination revealed moderate degree of skin pallor, bilateral pedal edema and an ovoid, firm, 6 × 5 cm, mobile, slightly tender, intra-abdominal lump in the epigastric region. [cancerjournal.net]
食道損傷 esophageal perforation食道穿孔 esophageal varices食道静脈瘤 esophagitis食道炎 esophagography食道造影 excretory duct導管 exocrine gland外分泌腺 external biliary fistula外胆汁瘻 extracorporeal shock wave lithotripsy (ESWL)体外衝撃波結石破砕術(ESWL) extrahepatic bile duct肝外胆管 f facial pallor [tokyo-med.ac.jp]
Respiratoric
- Pleural Effusion
If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. [healthengine.com.au]
If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. All content and media on the HealthEngine Blog is created and published online for informational purposes only. [healthinfo.healthengine.com.au]
Gastrointestinal
- Abdominal Pain
A 77-year-old woman was transferred to our institution for abdominal pain, fever, and leukocytosis. The patient complained of approximately 2 weeks of vague progressive abdominal pain accompanied by fever, chills, nausea, and anorexia. [ajronline.org]
Patients usually present with small bowel obstruction and abdominal pain in their sixth or seventh decade of life. [nature.com]
A 56-year-old male was admitted in the surgical ward with history of loss of appetite, weight loss, malaise, abdominal distention, melena and abdominal pain of 1-month duration. [go.gale.com]
Abdominal pain: Like gas and bloating, abdominal pain is nonspecific and can have many possible causes. When pain is present, it may be noted in the region known for pain with appendicitis, McBurney's point. [verywellhealth.com]
Abdominal pain: Like gas and bloating, abdominal pain is nonspecific and can have many possible causes. When pain is present, it may be noted in the region known for pain with appendicitis, McBurney's point. [verywell.com]
- Diarrhea
Abstract INTRODUCTION Carcinoma of the cecum and ascending colon is commonly believed to produce symptoms of anemia, diarrhea, and alternating diarrhea and constipation. [annals.org]
A 52 year-old Hispanic man without significant past medical, surgical or family history presented with diffuse, intermittent, crampy abdominal pain and diarrhea of one week duration. [nature.com]
He had a four-month history of abdominal discomfort, namely intermittent abdominal cramping pain of mild to moderate severity in the middle and lower quadrants, and diarrhea with occasional traces of blood, unquantified weight loss and nausea, and without [scielo.mec.pt]
Symptoms of colorectal cancer include Diarrhea or constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or [icdlist.com]
Apartment, 114/A, Barasat Road, Kolkata - 700 110 India Source of Support: None, Conflict of Interest: None DOI: 10.4103/0973-1482.126483 A 65-year-old male presented with painless hematochezia associated with episodic cramps in upper abdomen, watery diarrhea [cancerjournal.net]
- Constipation
Abstract INTRODUCTION Carcinoma of the cecum and ascending colon is commonly believed to produce symptoms of anemia, diarrhea, and alternating diarrhea and constipation. [annals.org]
Constipation. Symptoms of bowel obstruction - nausea, vomiting. Weight loss. Pathogenesis - see pathogenesis of colorectal carcinoma. Clinical - serum: CEA elevated. [1] CA19-9 elevated. [librepathology.org]
Symptoms of colorectal cancer include Diarrhea or constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or [icdlist.com]
Bowel symptoms that can occur in patients with cecal carcinoma include abdominal pain, constipation, weight loss, loss of appetite and vomiting, notes Santosh Kumar Mondal of the Department of Pathology, Medical College, Kolkata, India in a 2009 issue [livestrong.com]
[…] prognostic factor Clinical features Increased carcinoma risk in patients with polyposis syndromes, Lynch syndrome and inflammatory bowel disease Right sided tumors cause anemia, weakness and fatigue Left sided tumors cause change in bowel habits (diarrhea or constipation [pathologyoutlines.com]
- Hematochezia
Case report: An 18-year-old female Egyptian patient was admitted with hematochezia and remarkable anemia. [dovepress.com]
[…] old woman with abdominal pain and hematochezia. [endoatlas.com]
Proximal tumors will cause occult fecal blood and anemia, whereas distal tumors will cause more changes in bowel habits and hematochezia. [med-ed.virginia.edu]
Patients with right-side colon adenocarcinoma usually present with cachexia, weight loss, anemia, and positive fecal occult blood unlike those with left-sided colon cancers, which usually manifest with changes in bowel habit, hematochezia, and symptoms [hindawi.com]
- Abdominal Mass
A 41-year-old male patient was admitted because of a palpable abdominal mass. Abdominal computed tomography revealed a 6-cm, peripheral wall-enhanced, round, cystic mass in the cecal area. [kjim.org]
Bloody stool and a palpable abdominal mass were seen more often with nearly 27% and 34% respectively (6). [jgo.amegroups.com]
Hormonally inactive tumors often have a nonspecific presentation such as an abdominal mass and/or pain. The majority of patients present with stage I disease. Most tumors are unilateral (>90% of cases) and confined to the ovaries. [radiopaedia.org]
mass, +/-rectal mass, +/-signs of bowel obstruction (nausea, vomiting), +/-narrow caliber stools Symptoms +/-constipation Prevalence common Blood work +/- anemia (microcytic), +/-CEA elevated Radiology +/-"apple core" lesion (classic), +/-findings of [librepathology.org]
Examination revealed a firm 6 x 5 cm, intra-abdominal, epigastric mass. Colonoscopy up to 90 cm showed a stenosing, ulcero-proliferative lesion in the transverse colon. No synchronous lesion was detected. [cancerjournal.net]
Neurologic
- Peripheral Neuropathy
[…] sensorial neuropathy (12.4% >grade 3). [cancer.gov]
Workup
Our case showed clinical features primarily because of adenocarcinoma of caecum and coexistence with other primary neoplasm, i.e., RCC that was diagnosed on CT scan of abdomen during workup staging. [omicsonline.org]
Lab workup and abdominal/chest radiographs demonstrated no significant findings. Given the good clinical condition of the patient, she was admitted to the Geriatric Unit to monitor her progress and complete further studies. [elsevier.es]
Investigations Colonoscopy (best), look for synchronous lesions - Alternative: air contrast barium enema (“apple core” lesion) + sigmoidoscopy If a patient is FOBT +ve, microcytic anemia or has a change in bowel habits, do colonoscopy Metastatic workup [slideshare.net]
In addition, every medical doctor should always try to perform thorough medical workup of his patients in order to avoid overlooking tiny, but sometimes crucial, aspects leading to diagnosis. [hindawi.com]
More importantly, the patient had a completely negative workup for primary colon cancer. Hence we feel that our case is most consistent with urothelial-type adenocarcinoma of the prostate gland showing a degree of enteric differentiation. [scielo.br]
Serum
- Microcytic Anemia
Investigations Colonoscopy (best), look for synchronous lesions - Alternative: air contrast barium enema (“apple core” lesion) + sigmoidoscopy If a patient is FOBT +ve, microcytic anemia or has a change in bowel habits, do colonoscopy Metastatic workup [slideshare.net]
Pleura
- Pleural Effusion
If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. [healthengine.com.au]
If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. All content and media on the HealthEngine Blog is created and published online for informational purposes only. [healthinfo.healthengine.com.au]
Laboratory
- Leukocytosis
View larger version (53K) Fig. 1A. —77-year-old woman transferred to our institution with abdominal pain, fever, and leukocytosis. [ajronline.org]
Laboratory work-up results reported hypochromic anemia, leukocytosis with no neutrophilia, and elevated C-reactive protein. [revistagastroenterologiamexico.org]
Typically, a patient with a closed loop obstruction will manifest tachycardia, leukocytosis, fever, or constant pain, but a lack of these symptoms does not exclude the diagnosis [1]. [wjso.biomedcentral.com]
Treatment
The Physiology of the Cochlea Sammelreferat 113 Cesarean Section in the Treatment of Eclampsia 119 No 2 104 A MONTHLY JOURNAL 112 CONTENTS 127 nd Avenue and Twentieth Street 234 FostGraduate 212 The Symptomatology and Therapeutics of Fear A CRAMER 247 [books.google.it]
[…] make curative surgery possible. When rectal excision possible, aim should be to restore gastrointestinal continuity and continence by preserving anal sphincter Treatment 14 15. 1. [slideshare.net]
[…] to primary tumor treatment. [jcancer.org]
We report 2 patients with conventional prostatic adenocarcinoma who developed sarcomatoid carcinoma of probable prostatic origin 6 and 2.5 years after radiation treatment (seed implantation and external beam). [indiana.pure.elsevier.com]
High grade or abnormal cancer cells, or tumors that have caused a blockage or perforation of the colon may warrant further treatment. [coloncancercoalition.org]
Prognosis
Occasionally it will cause perforation, which carries a worse prognosis. We report a case of perforated adenocarcinoma of the cecum that presented as an abscess of the thigh. We also present a review of the literature on this subject. [ncbi.nlm.nih.gov]
Low grade: Well-differentiated 11 per cent prognosis good; b. Average grade, 64 per cent prognosis fair c. [slideshare.net]
“Obstruction and perforation in colorectal adenocarcinoma: an analysis of prognosis and current trends,” Surgery.2000 ;4(127):370 – 6. [4] MPisano, LZorcolo, CMerli et al. 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation [eurorad.org]
However, in general, prognosis in patients with unresectable disease is extremely poor.3 In the present case, the patient had reached a late clinical stage, with nodal and distant metastases, which resulted in a poor prognosis. [dovepress.com]
These have a worse prognosis than non-mucinous carsinomas. Photomicrograph of a primary mucinous adenocarcinoma. Click to enlarge. [oncolex.org]
Etiology
BACKGROUND: Caecum is the dilated part of the right colon situated in the right iliac fossa, therefore the etiology of this cancer is similar to those of the rest of the colon. [ncbi.nlm.nih.gov]
In the beginning, this abscess was considered to be of tuberculous etiology. In adition, a review of the relevant literature is presented in the following study. [annalsgastro.gr]
A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance [books.google.it]
It is most commonly emergency explorative laparotomy which clarifies the etiology of the occlusion. [annaliitalianidichirurgia.it]
Intussusception in the adult is a rare entity that differs greatly in etiology compared with that seen in the pediatric population. [wjgnet.com]
Epidemiology
Links: epidemiology aetiology and risk factors symptoms signs spread investigations differential diagnosis treatment prognosis [gpnotebook.com]
A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance [books.google.it]
English: BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]
Summary Epidemiology Bloom syndrome (BSyn) overall prevalence is unknown, but in the Ashkenazi Jewish population it is estimated at approximately 1/ 48,000 births. [orpha.net]
Clinical,epidemiological characteristics of 3870 cases of colorectal cancers in Guangdong region. Zhonghua Nei Ke Za Zhi 2006;45:9-12. [PUBMED] [FULLTEXT] 9. Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. [cancerjournal.net]
Pathophysiology
Pathophysiology 11. Prevention Increase fibre in diet Decrease animal fat and red meat, Decrease smoking and EtOH Increase exercise and decrease BMI Secondary prevention with screening 12. [slideshare.net]
Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126. National Cancer Institute website. [medlineplus.gov]
From colonic polyps to colon cancer: pathophysiology, clinical presentation, and diagnosis. Clin Lab Med2005; 25: 135–177. Crossref, Medline, Google Scholar 10 HaraAK, Johnson CD, Reed JE. Colorectal lesions: evaluation with CT colography. [pubs.rsna.org]
Pathophysiology Genetically, colorectal cancer represents a complex disease, and genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. [emedicine.medscape.com]
Prevention
Canadian Task Force on Preventive Health Caregrading of health promotion actions A: Good evidence to D: Fair evidence to recommend the recommend against the preventive health preventive health measure measure B: Fair evidence to E: Good evidence [slideshare.net]
The best thing you can do to prevent esophageal cancer is to not smoke or drink too much alcohol. Visit our prevention and screening section to learn how to manage your risk. [mdanderson.org]
For this reason, doctors recommend regular screening tests to help prevent colon cancer by identifying and removing polyps before they turn into cancer. [mayoclinic.org]
However, this complication has the potential to be devastating and its prevention is a priority. Laparoscopic approach in CRS reduces the tactile feedback of the surgeon who has to rely only on visual identification to prevent iatrogenic injury. [websurg.com]
Prevention Early detection is the key to prevention. Having intestinal polyps removed before they become cancerous may help prevent colon cancer. Physicians recommend having a sigmoidoscopy every three to five years beginning at age 50. [healthyliving.azcentral.com]