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2.1
Cecal Adenocarcinoma
Adenocarcinoma of Cecum

Presentation

Home All Journals Baylor University Medical Center Proceedings List of Issues Volume 28, Issue 2 Cecal Adenocarcinoma Presenting as Colon .... 1 CrossRef citations to date Case Studies Cecal Adenocarcinoma Presenting as Colonic Intussusception in Adulthood [tandfonline.com]

An isolated tumor nodule is present adjacent to the muscularis propria of the small bowel, however definitive ileal invasion is not identified. [radiopaedia.org]

In a large autopsy series, metastases to the gallbladder were present in 5.8% of patients [8, 9]. Chen et al. reported a case of transverse colon cancer presenting with manifestations of cholecystitis. [hindawi.com]

In the present case, separate appendiceal mucinous cystadenoma was concomitant with RCT. [spandidos-publications.com]

Entire Body System

  • Anemia

    Left: Adenocarcinoma in an 85 year-old man with anemia and occult bleeding. Center: Sessile lesion in an 86 year-old man with anemia but no history of bleeding. [endoatlas.com]

    A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia. A Tc-99m pertechnetate abdominal scan was positive and surgery revealed an adenocarcinoma of the cecum. No Meckel's diverticulum was identified. [ncbi.nlm.nih.gov]

    He then suffered anemia in November 2004. Colonoscopy showed findings compatible with mild ulcerative colitis, and detected a type-2 tumor in the cecum that proved in a biopsy to be well differentiated adenocarcinoma. [jstage.jst.go.jp]

    Anemia, however, was related to a better survival, especially in patients with a Dukes' B carcinoma. Clinicopathological staging according to Dukes' is closely related to survival. [onlinelibrary.wiley.com]

    Original Articles: PDF Only Abstract Author Information Authors A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia. [journals.lww.com]

  • Weight Loss

    A 56-year-old male was admitted in the surgical ward with history of loss of appetite, weight loss, malaise, abdominal distention, melena and abdominal pain of 1-month duration. [go.gale.com]

    Patients who have unexplained weight loss are less likely to respond compared to patients without unexplained weight loss, and patients with cancer localized to the cecal/ascending colon were likely to have worse response to bevacizumab treatment. [jcancer.org]

    Common presentations of CRC include alterations in bowel habit, weight loss, and lower gastrointestinal bleeding. [hindawi.com]

    He had a four-month history of abdominal discomfort, namely intermittent abdominal cramping pain of mild to moderate severity in the middle and lower quadrants, and diarrhea with occasional traces of blood, unquantified weight loss and nausea, and without [scielo.mec.pt]

    Center: Large cecal carcinoma in a 91 year-old woman with weight loss, anemia and an episode of melena; she also had a large villous adenoma in the left colon. [endoatlas.com]

  • Pallor

    Anemia can lead to fatigue, weakness and pallor. The cecum, a pouchlike structure, lies very close to the appendix. [livestrong.com]

    Physical examination revealed moderate degree of skin pallor, bilateral pedal edema and an ovoid, firm, 6 × 5 cm, mobile, slightly tender, intra-abdominal lump in the epigastric region. [cancerjournal.net]

    食道損傷 esophageal perforation食道穿孔 esophageal varices食道静脈瘤 esophagitis食道炎 esophagography食道造影 excretory duct導管 exocrine gland外分泌腺 external biliary fistula外胆汁瘻 extracorporeal shock wave lithotripsy (ESWL)体外衝撃波結石破砕術(ESWL) extrahepatic bile duct肝外胆管 f facial pallor [tokyo-med.ac.jp]

Respiratoric

  • Pleural Effusion

    If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. All content and media on the HealthEngine Blog is created and published online for informational purposes only. [healthinfo.healthengine.com.au]

    If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. [myvmc.com]

Gastrointestinal

  • Abdominal Pain

    A 77-year-old woman presented with a 1-month history of intermittent abdominal pain associated with nausea and distended abdomen. Imaging showed a complex elongated sausage-shaped mass in the transverse colon with no obstructive pattern or free air. [tandfonline.com]

    A 77-year-old woman was transferred to our institution for abdominal pain, fever, and leukocytosis. The patient complained of approximately 2 weeks of vague progressive abdominal pain accompanied by fever, chills, nausea, and anorexia. [ajronline.org]

    Patients usually present with small bowel obstruction and abdominal pain in their sixth or seventh decade of life. [nature.com]

    A 56-year-old male was admitted in the surgical ward with history of loss of appetite, weight loss, malaise, abdominal distention, melena and abdominal pain of 1-month duration. [go.gale.com]

  • Diarrhea

    Abstract INTRODUCTION Carcinoma of the cecum and ascending colon is commonly believed to produce symptoms of anemia, diarrhea, and alternating diarrhea and constipation. [annals.org]

    He had a four-month history of abdominal discomfort, namely intermittent abdominal cramping pain of mild to moderate severity in the middle and lower quadrants, and diarrhea with occasional traces of blood, unquantified weight loss and nausea, and without [scielo.mec.pt]

    A 52 year-old Hispanic man without significant past medical, surgical or family history presented with diffuse, intermittent, crampy abdominal pain and diarrhea of one week duration. [nature.com]

    Apartment, 114/A, Barasat Road, Kolkata - 700 110 India Source of Support: None, Conflict of Interest: None DOI: 10.4103/0973-1482.126483 A 65-year-old male presented with painless hematochezia associated with episodic cramps in upper abdomen, watery diarrhea [cancerjournal.net]

    Symptoms of colorectal cancer include Diarrhea or constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or [icdlist.com]

  • Constipation

    Abstract INTRODUCTION Carcinoma of the cecum and ascending colon is commonly believed to produce symptoms of anemia, diarrhea, and alternating diarrhea and constipation. [annals.org]

    Constipation. Symptoms of bowel obstruction - nausea, vomiting. Weight loss. Pathogenesis - see pathogenesis of colorectal carcinoma. Clinical - serum: CEA elevated. [1] CA19-9 elevated. [librepathology.org]

    Bowel symptoms that can occur in patients with cecal carcinoma include abdominal pain, constipation, weight loss, loss of appetite and vomiting, notes Santosh Kumar Mondal of the Department of Pathology, Medical College, Kolkata, India in a 2009 issue [livestrong.com]

    Symptoms of colorectal cancer include Diarrhea or constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or [icdlist.com]

  • Hematochezia

    Case report: An 18-year-old female Egyptian patient was admitted with hematochezia and remarkable anemia. [dovepress.com]

    […] old woman with abdominal pain and hematochezia. [endoatlas.com]

    Proximal tumors will cause occult fecal blood and anemia, whereas distal tumors will cause more changes in bowel habits and hematochezia. [med-ed.virginia.edu]

    Patients with right-side colon adenocarcinoma usually present with cachexia, weight loss, anemia, and positive fecal occult blood unlike those with left-sided colon cancers, which usually manifest with changes in bowel habit, hematochezia, and symptoms [hindawi.com]

  • Melena

    A 56-year-old male was admitted in the surgical ward with history of loss of appetite, weight loss, malaise, abdominal distention, melena and abdominal pain of 1-month duration. [go.gale.com]

    Center: Large cecal carcinoma in a 91 year-old woman with weight loss, anemia and an episode of melena; she also had a large villous adenoma in the left colon. [endoatlas.com]

    She denied fevers, melena, hematochezia, recent travel, or infections. She was afebrile but mildly hypertensive and tachycardic, with a heart rate >100 bpm and 94% oxygen saturation on ambient room air. [acgcasereports.gi.org]

    Clinical Features Often asymptomatic Hematochezia / melena, abdominal pain, change in bowel habits Weakness, anemia, weight loss, palpable mass, obstructionSpread Direct extension, lymphatic, hematogenous (liver most common, lung, rarely bone and [slideshare.net]

Neurologic

  • Peripheral Neuropathy

    […] sensorial neuropathy (12.4% >grade 3). [cancer.gov]

Workup

Our case showed clinical features primarily because of adenocarcinoma of caecum and coexistence with other primary neoplasm, i.e., RCC that was diagnosed on CT scan of abdomen during workup staging. [omicsonline.org]

Lab workup and abdominal/chest radiographs demonstrated no significant findings. Given the good clinical condition of the patient, she was admitted to the Geriatric Unit to monitor her progress and complete further studies. [elsevier.es]

Investigations Colonoscopy (best), look for synchronous lesions - Alternative: air contrast barium enema (“apple core” lesion) + sigmoidoscopy If a patient is FOBT +ve, microcytic anemia or has a change in bowel habits, do colonoscopy Metastatic workup [slideshare.net]

In addition, every medical doctor should always try to perform thorough medical workup of his patients in order to avoid overlooking tiny, but sometimes crucial, aspects leading to diagnosis. [hindawi.com]

More importantly, the patient had a completely negative workup for primary colon cancer. Hence we feel that our case is most consistent with urothelial-type adenocarcinoma of the prostate gland showing a degree of enteric differentiation. [scielo.br]

Serum

  • Microcytic Anemia

    Investigations Colonoscopy (best), look for synchronous lesions - Alternative: air contrast barium enema (“apple core” lesion) + sigmoidoscopy If a patient is FOBT +ve, microcytic anemia or has a change in bowel habits, do colonoscopy Metastatic workup [slideshare.net]

Pleura

  • Pleural Effusion

    If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. All content and media on the HealthEngine Blog is created and published online for informational purposes only. [healthinfo.healthengine.com.au]

    If lung metastases are present there may be pleural effusions causing breathlessness. Effusions may require drainage. [myvmc.com]

Treatment

[…] to primary tumor treatment. [jcancer.org]

This highlights the importance of accurate immunohistochemistry and imaging in planning further management and treatment. [eprints.whiterose.ac.uk]

Adult intussusception with cecal adenocarcinoma: Successful treatment by laparoscopy-assisted surgery following preoperative reduction. [wjgnet.com]

They only give information about the cancer itself and the precise type of treatment you might need. Remember that not every patient with colon cancer even needs other types of treatment besides surgery. [cancer.org]

Prognosis

“Obstruction and perforation in colorectal adenocarcinoma: an analysis of prognosis and current trends,” Surgery.2000 ;4(127):370 – 6. [4] MPisano, LZorcolo, CMerli et al. 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation [eurorad.org]

Occasionally it will cause perforation, which carries a worse prognosis. We report a case of perforated adenocarcinoma of the cecum that presented as an abscess of the thigh. We also present a review of the literature on this subject. [ncbi.nlm.nih.gov]

Low grade:  Well-differentiated 11 per cent prognosis good; b. Average grade,  64 per cent prognosis fair c. [slideshare.net]

Etiology

BACKGROUND: Caecum is the dilated part of the right colon situated in the right iliac fossa, therefore the etiology of this cancer is similar to those of the rest of the colon. [ncbi.nlm.nih.gov]

Intussusception in the adult is a rare entity that differs greatly in etiology compared with that seen in the pediatric population. [wjgnet.com]

It is most commonly emergency explorative laparotomy which clarifies the etiology of the occlusion. [annaliitalianidichirurgia.it]

Histological evaluation determined this was locally invasive pancreatic adenocarcinoma, and therefore the true etiology of the original cecal perforation. [wjso.biomedcentral.com]

A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance [books.google.it]

Epidemiology

A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance [books.google.it]

Links: epidemiology aetiology and risk factors symptoms signs spread investigations differential diagnosis treatment prognosis [gpnotebook.com]

English: BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]

Summary Epidemiology Bloom syndrome (BSyn) overall prevalence is unknown, but in the Ashkenazi Jewish population it is estimated at approximately 1/ 48,000 births. [orpha.net]

Using nationally representative Surveillance, Epidemiology, and End Results (SEER) data, we compared survival rates associated with colon cancer stages defined according to both AJCC systems. [academic.oup.com]

Pathophysiology

Pathophysiology 11. Prevention Increase fibre in diet Decrease animal fat and red meat, Decrease smoking and EtOH Increase exercise and decrease BMI Secondary prevention with screening 12. [slideshare.net]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126. National Cancer Institute website. [medlineplus.gov]

From colonic polyps to colon cancer: pathophysiology, clinical presentation, and diagnosis. Clin Lab Med2005; 25: 135–177. Crossref, Medline, Google Scholar 10 HaraAK, Johnson CD, Reed JE. Colorectal lesions: evaluation with CT colography. [pubs.rsna.org]

Pathophysiology Genetically, colorectal cancer represents a complex disease, and genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. [emedicine.medscape.com]

Prevention

Canadian Task Force on Preventive Health Caregrading of health promotion actions A: Good evidence to  D: Fair evidence to recommend the recommend against the preventive health preventive health measure measure B: Fair evidence to  E: Good evidence [slideshare.net]

However, this complication has the potential to be devastating and its prevention is a priority. Laparoscopic approach in CRS reduces the tactile feedback of the surgeon who has to rely only on visual identification to prevent iatrogenic injury. [websurg.com]

Genetic prenatal screening for early detection is the best option for primary prevention. Keywords: isolated, Peutz–Jeghers syndrome, hematochezia © 2011 The Author(s). This work is published and licensed by Dove Medical Press Limited. [dovepress.com]

The best thing you can do to prevent esophageal cancer is to not smoke or drink too much alcohol. Visit our prevention and screening section to learn how to manage your risk. [mdanderson.org]

For this reason, doctors recommend regular screening tests to help prevent colon cancer by identifying and removing polyps before they turn into cancer. [mayoclinic.org]

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