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Cecal Adenocarcinoma

Adenocarcinoma of Cecum


Presentation

  • We report a case of perforated adenocarcinoma of the cecum that presented as an abscess of the thigh. We also present a review of the literature on this subject.[ncbi.nlm.nih.gov]
  • Analysis of the rhabdoid cells with molecular techniques is also presented.[ncbi.nlm.nih.gov]
  • We report a 55-year-old man who presented with a gastric stromal tumor and cecal adenocarcinoma, necessitating right hemicolectomy and partial gastrectomy at the same sitting.[ncbi.nlm.nih.gov]
  • Abstract A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia. A Tc-99m pertechnetate abdominal scan was positive and surgery revealed an adenocarcinoma of the cecum. No Meckel's diverticulum was identified.[ncbi.nlm.nih.gov]
  • Isolated extramural tumour deposits Present Apical node involvement Present Venous and small vessel invasion Intramural vein invasion Present Extramural vein invasion Present Small vessel invasion Present Perineural invasion Present Mismatch repair immunohistochemistry[radiopaedia.org]
Anemia
  • Abstract A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia. A Tc-99m pertechnetate abdominal scan was positive and surgery revealed an adenocarcinoma of the cecum. No Meckel's diverticulum was identified.[ncbi.nlm.nih.gov]
  • Original Articles: PDF Only Abstract Author Information Authors A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia.[journals.lww.com]
  • He then suffered anemia in November 2004. Colonoscopy showed findings compatible with mild ulcerative colitis, and detected a type-2 tumor in the cecum that proved in a biopsy to be well differentiated adenocarcinoma.[jstage.jst.go.jp]
  • Case report: An 18-year-old female Egyptian patient was admitted with hematochezia and remarkable anemia.[dovepress.com]
  • Left: Adenocarcinoma in an 85 year-old man with anemia and occult bleeding. Center: Sessile lesion in an 86 year-old man with anemia but no history of bleeding.[endoatlas.com]
Weight Loss
  • He had a four-month history of abdominal discomfort, namely intermittent abdominal cramping pain of mild to moderate severity in the middle and lower quadrants, and diarrhea with occasional traces of blood, unquantified weight loss and nausea, and without[scielo.mec.pt]
  • Weight loss. Pathogenesis - see pathogenesis of colorectal carcinoma . Clinical - serum: CEA elevated. [1] CA19-9 elevated. Colon cancer-specific antigen-2 (CCSA-2) elevated. [2] Relatively new; preliminary in 2014.[librepathology.org]
  • loss with no known reason Fatigue Nausea or vomiting Because you may not have symptoms at first, it's important to have screening tests.[icdlist.com]
  • Bowel symptoms that can occur in patients with cecal carcinoma include abdominal pain, constipation, weight loss, loss of appetite and vomiting, notes Santosh Kumar Mondal of the Department of Pathology, Medical College, Kolkata, India in a 2009 issue[livestrong.com]
  • Center: Large cecal carcinoma in a 91 year-old woman with weight loss, anemia and an episode of melena; she also had a large villous adenoma in the left colon.[endoatlas.com]
Pallor
  • Anemia can lead to fatigue, weakness and pallor. The cecum, a pouchlike structure, lies very close to the appendix.[livestrong.com]
  • Physical examination revealed moderate degree of skin pallor, bilateral pedal edema and an ovoid, firm, 6 5 cm, mobile, slightly tender, intra-abdominal lump in the epigastric region.[cancerjournal.net]
  • 食道損傷 esophageal perforation食道穿孔 esophageal varices食道静脈瘤 esophagitis食道炎 esophagography食道造影 excretory duct導管 exocrine gland外分泌腺 external biliary fistula外胆汁瘻 extracorporeal shock wave lithotripsy (ESWL)体外衝撃波結石破砕術(ESWL) extrahepatic bile duct肝外胆管 f facial pallor[tokyo-med.ac.jp]
Pleural Effusion
  • If lung metastases are present there may be pleural effusions causing breathlessness . Effusions may require drainage.[myvmc.com]
  • […] pancreatectomy膵切除術 pancreatic calcification膵石灰化 pancreatic cyst (cyst of pancreas)膵嚢胞 pancreatic duct cell carcinoma膵管癌 pancreatic functioning diagnostant (PFD) test (BT-PABA test, bentiromide test)PFD試験 BT-PABA試験、ベンチロミド試験 pancreatic juice膵液 pancreatic pleural[tokyo-med.ac.jp]
Abdominal Pain
  • Patients usually present with small bowel obstruction and abdominal pain in their sixth or seventh decade of life.[nature.com]
  • A 77-year-old woman presented with a 1-month history of intermittent abdominal pain associated with nausea and distended abdomen. Imaging showed a complex elongated sausage-shaped mass in the transverse colon with no obstructive pattern or free air.[tandfonline.com]
  • Three days later, upon admission, the patient complained of episodes of abdominal pain with intervals of moderate well-being, associated with nausea, vomiting and an inability to pass stool (but not gas) for 36 hours.[annaliitalianidichirurgia.it]
  • This torsion can lead to abdominal pain, swelling, cramps, nausea, and vomiting.[verywell.com]
Diarrhea
  • A 52 year-old Hispanic man without significant past medical, surgical or family history presented with diffuse, intermittent, crampy abdominal pain and diarrhea of one week duration.[nature.com]
  • He had a four-month history of abdominal discomfort, namely intermittent abdominal cramping pain of mild to moderate severity in the middle and lower quadrants, and diarrhea with occasional traces of blood, unquantified weight loss and nausea, and without[scielo.mec.pt]
  • Symptoms of colorectal cancer include Diarrhea or constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or[icdlist.com]
  • Chemoradiation-related toxicity Acute gastrointestinal toxicity as diarrhea and abdominal pain was the most frequent complication in patients receiving adjuvant chemoradiation.[e-roj.org]
  • […] important prognostic factor Clinical features Increased carcinoma risk in patients with polyposis syndromes, Lynch syndrome and inflammatory bowel disease Right sided tumors cause anemia, weakness and fatigue Left sided tumors cause change in bowel habits (diarrhea[pathologyoutlines.com]
Constipation
  • Constipation. Symptoms of bowel obstruction - nausea, vomiting. Weight loss. Pathogenesis - see pathogenesis of colorectal carcinoma . Clinical - serum: CEA elevated. [1] CA19-9 elevated.[librepathology.org]
  • Symptoms of colorectal cancer include Diarrhea or constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or[icdlist.com]
  • Bowel symptoms that can occur in patients with cecal carcinoma include abdominal pain, constipation, weight loss, loss of appetite and vomiting, notes Santosh Kumar Mondal of the Department of Pathology, Medical College, Kolkata, India in a 2009 issue[livestrong.com]
  • […] prognostic factor Clinical features Increased carcinoma risk in patients with polyposis syndromes, Lynch syndrome and inflammatory bowel disease Right sided tumors cause anemia, weakness and fatigue Left sided tumors cause change in bowel habits (diarrhea or constipation[pathologyoutlines.com]
Hematochezia
  • Case report: An 18-year-old female Egyptian patient was admitted with hematochezia and remarkable anemia.[dovepress.com]
  • […] old woman with abdominal pain and hematochezia.[endoatlas.com]
  • Proximal tumors will cause occult fecal blood and anemia, whereas distal tumors will cause more changes in bowel habits and hematochezia.[med-ed.virginia.edu]
  • Kumar Bhattacharjee Bhattacharjee, Flat No 5, 4th Floor, Suryatoran Apartment, 114/A, Barasat Road, Kolkata - 700 110 India Source of Support: None, Conflict of Interest: None DOI: 10.4103/0973-1482.126483 A 65-year-old male presented with painless hematochezia[cancerjournal.net]
  • […] gastrointestinal 胃腸の gastrojejunostomy胃空腸吻合術 gastroptosis胃下垂 glucose tolerance耐糖性 graft-versus-host disease (GVHD)移植片対宿主病 gram-negative bacilli グラム陰性桿菌 greater curvature大彎 h hamartoma過誤腫 heartburn胸やけ Helicobacter pylori ヘリコバクターピロリ hemangioma血管腫 hematemesis吐血 hematochezia[tokyo-med.ac.jp]
Melena
  • Center: Large cecal carcinoma in a 91 year-old woman with weight loss, anemia and an episode of melena; she also had a large villous adenoma in the left colon.[endoatlas.com]
  • Dark, tarry stools (melena): When bleeding occurs in the cecum and ascending colon, it usually causes black stools that can appear tar-like, rather than the bright red blood seen with bleeding lower in the digestive tract.[verywell.com]
  • 肝移植 longitudinal muscle縦走筋 lower digestive tract 下部消化管 lymphomaリンパ腫 m magnetic resonance cholangiopancreatography (MRCP)磁気共鳴胆道膵管造影(撮影)[法] main pancreatic duct主膵管 malabsorption of fat脂肪吸収障害 maldigestion消化不良 malnutrition栄養不良 mediastinum縦隔 megacolon巨大結腸 melena[tokyo-med.ac.jp]
Radiculopathy
  • Pelvic pain may be due to an upper lumbar or lower thoracic radiculopathy. This referral pattern must be recognized when evaluating cancer patients with occult pelvic pain.[ncbi.nlm.nih.gov]

Workup

Pleural Effusion
  • If lung metastases are present there may be pleural effusions causing breathlessness . Effusions may require drainage.[myvmc.com]
  • […] pancreatectomy膵切除術 pancreatic calcification膵石灰化 pancreatic cyst (cyst of pancreas)膵嚢胞 pancreatic duct cell carcinoma膵管癌 pancreatic functioning diagnostant (PFD) test (BT-PABA test, bentiromide test)PFD試験 BT-PABA試験、ベンチロミド試験 pancreatic juice膵液 pancreatic pleural[tokyo-med.ac.jp]

Treatment

  • The Physiology of the Cochlea Sammelreferat 113 Cesarean Section in the Treatment of Eclampsia 119 No 2 104 A MONTHLY JOURNAL 112 CONTENTS 127 nd Avenue and Twentieth Street 234 FostGraduate 212 The Symptomatology and Therapeutics of Fear A CRAMER 247[books.google.it]
  • CONCLUSIONS: The radical resection of primary duodenal adenocarcinoma is considered the treatment of choice, which should be accompanied by adjuvant chemotherapy preventing a recurrence at distant sites.[link.springer.com]
  • This unique pictorial resource is a superb complement to treatment handbooks and major oncological texts.[books.google.it]
  • These simple treatment plans could not spare the small bowel, which is main cause of treatment-related toxicity in abdominal radiation.[e-roj.org]
  • Surgical excision of the affected intestine is the recommended treatment of choice.[tandfonline.com]

Prognosis

  • Occasionally it will cause perforation, which carries a worse prognosis. We report a case of perforated adenocarcinoma of the cecum that presented as an abscess of the thigh. We also present a review of the literature on this subject.[ncbi.nlm.nih.gov]
  • Analysis was performed to determine the influence of stage and grade of the primary tumor on prognosis. Implications for adjuvant therapy are discussed.[ncbi.nlm.nih.gov]
  • However, it lacks specific symptoms and its diagnosis may be delayed with poor prognosis. Villous adenomas are considered as premalignant lesions with high risk malignant transformation.[link.springer.com]

Etiology

  • A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance[books.google.it]
  • It is most commonly emergency explorative laparotomy which clarifies the etiology of the occlusion.[annaliitalianidichirurgia.it]
  • With regard to the etiology of axillary lymph node metastasis of colorectal carcinoma, the last case cited suggests that the axillary lymph node metastasis may have developed from the site of the breast metastasis, which is considered as hematogenous[surgicalcasereports.springeropen.com]

Epidemiology

  • A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance[books.google.it]
  • Links: epidemiology aetiology and risk factors symptoms signs spread investigations differential diagnosis treatment prognosis[gpnotebook.co.uk]
  • Nevertheless, in the past few years epidemiological and clinical studies have shed new light on the management of patients with mucinous cancer.[esmo.org]
  • Using nationally representative Surveillance, Epidemiology, and End Results (SEER) data, we compared survival rates associated with colon cancer stages defined according to both AJCC systems.[academic.oup.com]
Sex distribution
Age distribution

Pathophysiology

  • Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126. National Cancer Institute website.[medlineplus.gov]

Prevention

  • Genetic prenatal screening for early detection is the best option for primary prevention. Keywords: isolated, Peutz–Jeghers syndrome, hematochezia This work is published and licensed by Dove Medical Press Limited.[dovepress.com]
  • CONCLUSIONS: The radical resection of primary duodenal adenocarcinoma is considered the treatment of choice, which should be accompanied by adjuvant chemotherapy preventing a recurrence at distant sites.[link.springer.com]
  • Prevention Early detection is the key to prevention. Having intestinal polyps removed before they become cancerous may help prevent colon cancer. Physicians recommend having a sigmoidoscopy every three to five years beginning at age 50.[healthyliving.azcentral.com]
  • Prevention Get screened for colon cancer People with an average risk of colon cancer can consider screening beginning at age 50.[mayoclinic.org]

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