Epidemiology of pneumococcal resistance in an urban hospital setting (presentation S2). Presented at: Annual Conference on Antimicrobial Resistance. Bethesda, MD, June 23–25, 2003. Google Scholar [doi.org]

CONCLUSIONS: The present study is unique in the literature for reporting for the first time gall bladder sludge and nephrolithiasis associated with cefotaxime use. [ncbi.nlm.nih.gov]

• Intravenous Administration

  Selective bowel decontamination consists of a 2- to 4-day intravenous administration of antibiotics, usually cefotaxime (unless the patient is already receiving antibiotic therapy) and topical application of non-resorbable antibiotics in the oropharyngeal [glosbe.com]

  There is no accumulation following administration of 1000 mg intravenously or 500 mg intramuscularly for 10 or 14 days. [bbpharma.sk]

• Severe Pain

  Oxycodone Oxycodone is indicated for the treatment of moderate to severe pain.[Label] There is also an extended release formulation indicated for chronic moderate to severe pain requiring continuous opioid analgesics for... [drugbank.ca]

• Nausea

  May cause diarrhea (yogurt, boiled milk, or buttermilk may help); GI distress or nausea (small, frequent meals, frequent oral care, chewing gum, or sucking lozenges may help). [web.archive.org]

  • Gastrointestinal : Diarrhea, nausea, and vomiting. What are the other precautions for Cefotaxime? Avoid excess dosage. What are the storage conditions for Cefotaxime? Store it at controlled room temperature (15-30°C). [medindia.net]

  […] serious side effects, including: easy bruising/bleeding, unusual tiredness, uncontrollable movements, mental/mood changes (such as confusion), seizures, signs of kidney problems (such as change in the amount of urine), signs of liver problems (such as nausea [webmd.com]

• Jaundice

  Jaundice (yellowing of the whites of the eyes or skin). Changes in kidney function with high doses. Disturbances in the normal numbers of blood cells in the blood. [netdoctor.co.uk]

  […] fever, sore throat, swollen glands or mouth ulcers unusual bleeding or bruising under the skin signs of anaemia, such as tiredness, headache, dizziness, being short of breath when exercising or looking pale yellowing of the skin or eyes, also known as jaundice [mydr.com.au]

• Osteoporosis

  This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, injectable osteoporosis medication, and some pain [rxlist.com]

• Muscle Weakness

  Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; skin rash, bruising, severe tingling, numbness, pain, muscle weakness; seizure (black-out or convulsions ); or severe skin reaction -- fever, sore throat, swelling [emedicinehealth.com]

• Agitation

  […] available premixed injection (frozen) at room temperature or in a refrigerator; do not thaw by immersion in a water bath or by exposure to microwave radiation. 230 A precipitate may have formed in the frozen injection, but should dissolve with little or no agitation [web.archive.org]

• Streptococcus Pneumoniae

  Molecular characterization of clinical isolates of Streptococcus pneumoniae with different susceptibilities to ceftriaxone and cefotaxime. [doi.org]

  It is now mandatory to test in-vitro susceptibilities of Streptococcus pneumoniae to penicillin G and other beta-lactam agents when meningitis is diagnosed in infants. [ncbi.nlm.nih.gov]

• Staphylococcus Aureus

  We investigated the effect of sub-MICs of bactericidal antibiotics on the susceptibility pattern of Staphylococcus aureus and evaluated the role of free radicals. [ncbi.nlm.nih.gov]

  Maximum dose: 2 grams Ceftizoxime (Cefizox) Moderate Staphylococcus aureus and Anaerobic Activity Adult: 1 to 2 grams IV every 8 to 12 hours Child: 50 mg/kg/dose IV every 6 to 8 hours Ceftriaxone (Rocephin) Least Staphylococcus and Anaerobic activity [fpnotebook.com]

  Antibiotic Class: Third-Generation Cephalosporin Antimicrobial Spectrum: Staphylococcus aureus (methicillin susceptible), Coagulase negative Staphylococci, Streptococcus pneumoniae (penicillin susceptible), Streptococcus spp., Haemophilus influenzae, [antimicrobe.org]

• Salmonella Typhi

  Salmonella spp. (including Salmonella typhi ) Shigella spp. OVERDOSAGE The acute toxicity of CLAFORAN was evaluated in neonatal and adult mice and rats. Significant mortality was seen at parenteral doses in excess of 6000 mg/kg/day in all groups. [druglib.com]

  Infections Treatment of typhoid fever (enteric fever) or septicemia caused by Salmonella typhi or S. paratyphi †, including multidrug-resistant strains. 275 306 Treatment of gastroenteritis caused by Salmonella † (e.g., S. enteritidis, S. typhimurium [web.archive.org]

• Borrelia Burgdorferi

  Penicillin-resistant s trains ) Streptococcus pyogenes Gram-negative aerobes Borrelia burgdorferi Escherichia coli % Haemophilus influenzae Klebsiella oxytoca % Klebsiella pneumoniae #% Moraxella catarrhalis Morganella morganii Neisseria gonorrhoeae Neisseria [bbpharma.sk]

  In vitro and in vivo susceptibility of Borrelia burgdorferi. Eur J Clin Microbiol. 1987; 6:424-6. [PubMed 3665899] 266. Hassler D, Zoller L, Haude M et al. [web.archive.org]

  In vitro and in vivo susceptibility of Borrelia burgdorferi. Eur J Clin Microbiol. 1987; 6:424-6. http://www.ncbi.nlm.nih.gov/pubmed/3665899?dopt=AbstractPlus 266. Hassler D, Zoller L, Haude M et al. [drugs.com]

• Legionella Pneumophila

  Legionella pneumophila Mycoplasma spp. Treponema pallidum Literature data, reference books and therapy guidelines support susceptibility. ° No current surveillance data available. [bbpharma.sk]

Treatment of bacterial meningitis. N Engl J Med. 1997; 337:793-4. http://www.ncbi.nlm.nih.gov/pubmed/9289652?dopt=AbstractPlus 326. Quagliarello V, Scheld WM. Treatment of bacterial meningitis. [drugs.com]

Update to CDC's Sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. MMWR Morb Mortal Wkly Rep. 2012; 61:590-4. [PubMed 22874837] 167. [web.archive.org]

The patient was clinically cured after treatment with ceftriaxone 500 mg intramuscularly and this is the only third generation cephalosporin that should be used for first-line empiric treatment of gonorrhoea. [ncbi.nlm.nih.gov]

IIB Breast Cancer / Stage IIB Breast Cancer AJCC v6 and v7 / Stage IIIA Breast Cancer / Stage IIIA Breast Cancer AJCC v7 1 3Active Not RecruitingTreatment Childhood Atypical Teratoid/Rhabdoid Tumor 1 3Active Not RecruitingTreatment Childhood Favorable Prognosis [drugbank.ca]

METHODS: This prospective study included 208 (109 males and 99 females) end-stage renal disease (ESRD) patients of diverse etiology enrolled for long-term HD from July 2002 to June 2003 at our tertiary care hospital. [ncbi.nlm.nih.gov]

Gov't MeSH terms Amino Acid Sequence Amino Acid Substitution Bacterial Proteins/chemistry Bacterial Proteins/genetics* Cefotaxime/pharmacology* Cross Infection/epidemiology Cross Infection/microbiology DNA, Bacterial/genetics Drug Resistance, Multiple [ncbi.nlm.nih.gov]

Clinical and Epidemiological Study First Online: 12 September 2008 Abstract Introduction: Continuous infusion of cefotaxime, as opposed to intermittent infusion, seems to be advantageous for a number of reasons. [doi.org]

European Centre for Disease Prevention and Control Antimicrobial resistance in the EU/EEA (EARS-Net)—annual epidemiological report for 2019. 8. Paterson DL “Collateral damage” from cephalosporin or quinolone antibiotic therapy. [thelancet.com]

Objectives: Describe the pathophysiology of cefotaxime resistance. Identify the most common adverse events associated with cefotaxime therapy. Outline the mechanism of action of cefotaxime. [ncbi.nlm.nih.gov]

To date, there is no strategy for the prevention of early neonatal sepsis due to ampicillin-resistant E. coli. [ncbi.nlm.nih.gov]

This medicine is also given before, during, and after certain types of surgery to prevent infections. Cefotaxime injection belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. [mayoclinic.org]

(via cephalosporin ) antibacterial drug A drug used to treat or prevent bacterial infections. [ebi.ac.uk]