We report a 12-year female who presented with simultaneous celiac disease and acute pancreatitis Case Presentation A 12-year girl was referred to the ER with one day history of severe epigastric abdominal pain and vomiting. [omicsonline.org]

The cell of origin of indolent small intestinal CD4 T-cell lymphomas is not known at present. [journals.plos.org]

Definition / general Enteropathy associated T cell lymphoma (EATL) is an intestinal tumor of intraepithelial T lymphocytes showing varying degrees of transformation but usually presenting as a tumor composed of large, often polymorphic lymphoid cells, [pathologyoutlines.com]

Raynaud phenomenon is present in most patients with SSc and is often the earliest manifestation of disease. [emedicine.medscape.com]

• Short Stature

  Prevalence of celiac disease in Brazilian children of short stature. Braz. J. Med. Biol. Res. 37, 55–60 (2004). 100. Hyer, W., Cotterill, A. M. & Savage, M. O. Common causes of short stature detectable by a height surveillance programme. J. Med. [nature.com]

  stature, which can occur when childhood celiac disease prevents nutrient absorption and seizures. [westchestergi.com]

• Infertility

  Without treatment, people with celiac disease can develop complications like malnutrition, cancer, infertility, osteoporosis, anemia, and seizures. Diagnosis involves blood tests and a biopsy of the small intestine. [westchestergi.com]

  […] in a low number of red blood cells (anemia), vitamin deficiencies, low bone mineral density (osteoporosis), itchy skin rashes (dermatitis herpetiformis), defects in the enamel of the teeth, chronic fatigue, joint pain, poor growth, delayed puberty, infertility [icdlist.com]

• Weight Gain

  To investigate her hypoalbuminemia and poor weight gain, a tissue transglutaminase IgA (tTG) was obtained. [omicsonline.org]

• Pallor

  […] apoptosis 4 Liver biopsy showing apoptosis of hepatocytes 5 Esophageal endoscopy showing lower esophageal metaplasia M1 Select Answer to see Preferred Response PREFERRED RESPONSE 2 (M1.GI.77) A 30-year-old Caucasian female presents with weight loss, pallor [medbullets.com]

• Diarrhea

  Traveler’s diarrhea Traveler’s diarrhea is the abnormally swift passage of watery waste material through the large intestine, with consequent discharge of loose feces. Traveler’s diarrhea is accompanied by cramping and lasts a few days. [britannica.com]

  Drugs to control diarrhea and intestinal spasms can sometimes help relieve cramps and diarrhea. Infusion with the monoclonal-antibody drug infliximab can help patients who have not gotten adequate response from other therapies. diet. [ariahealth.org]

  • Does not have increased secretions as does sprue • May be associated with pneumatosis intestinalis Whipple’s Disease • Glycoprotein in the lamina propria of the small bowel is Sudan-negative, PAS-positive • Clinically: arthralgia, abdominal pain, diarrhea [learningradiology.com]

  Young children most often show growth failure, weight loss, diarrhea, constipation or abdominal distension. [westchestergi.com]

  Intestinal damage causes diarrhea and poor absorption of nutrients, which may lead to weight loss. Abdominal pain, swelling (distention), and food intolerances are common in celiac disease. [icdlist.com]

• Intestinal Disease

  Nassar, V.H., Salem, P.A., Shadid, M.J.: Mediterranean abdominal lymphoma or immunoproliferative small intestine disease. II Pathological aspects. [link.springer.com]

  Van Weyenberg SJ, Bouman K, Jacobs MA, Halloran BP, Van der Peet DL, Mulder CJ, et al: Comparison of MR enteroclysis with video capsule endoscopy in the investigation of small-intestinal disease. Abdom Imaging 2013;38:42-51. [karger.com]

  Erythema nodosum lesions usually parallel the intestinal disease, which provides helpful information on the overall disease. Histologically, the lesions are characterized by septal panniculitis. [emedicine.medscape.com]

• Dermatitis

  Small-bowel changes in dermatitis herpetiformis. Lancet 2, 1280–1282 (1966). 56. Zone, J. J. Skin manifestations of celiac disease. Gastroenterology 128, S87–S91 (2005). 57. Bolotin, D. & Petronic-Rosic, V. Dermatitis herpetiformis. Part, I. [nature.com]

  Elevation of IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis. Br J Dermatol. 2008 Jul. 159(1):120-4. [Medline]. Katz SI, Hall RP 3rd, Lawley TJ, Strober W. Dermatitis herpetiformis: the skin and the gut. [emedicine.medscape.com]

  Etiology Lymphomas of small intestine may derive from various subsets of intestinal intraepithelial lymphocytes that are differentially activated by diverse antigenic stimuli Association with celiac disease: positive serology, HLA DQ2 or DQ8 expression, dermatitis [pathologyoutlines.com]

  These health problems may include iron deficiency that results in a low number of red blood cells (anemia), vitamin deficiencies, low bone mineral density (osteoporosis), itchy skin rashes (dermatitis herpetiformis), defects in the enamel of the teeth [icdlist.com]

  In a limited number of people with celiac disease, a gluten related skin disorder, called dermatitis herpetiformis, appears as small itchy blisters on the skin surface, typically on body pressure points such as the elbows, knees, and feet. [westchestergi.com]

• Alopecia

  Celiac disease and alopecia areata: report of a new association. Gastroenterology 109, 1333–1337 (1995). 68. Bardella, M. T. et al. Alopecia areata and coeliac disease: no effect of a gluten-free diet on hair growth. [nature.com]

  An unusual syndrome of polyposis, pigmentation, alopecia, and onychatrophia. N Engl J Med. 1955. 252:1011-1015. Sweetser S, Ahlquist DA, Osborn NK, Sanderson SO, Smyrk TC, Chari ST, et al. [emedicine.medscape.com]

• Excoriation

  Pruritus can lead to significant excoriation and secondary changes, leading to misdiagnosis of atopic dermatitis. [emedicine.medscape.com]

• Hyperpigmentation

  The dermatologic manifestation of the disease mainly involves skin hyperpigmentation. [emedicine.medscape.com]

• Papule

  Note the shiny, reddish, telangiectatic group of papules in the umbilicus. [emedicine.medscape.com]

Conclusions: Small bowel imaging and especially cross-sectional enteroclysis techniques are important extensions to the diagnostic workup of clinicians involved in the care of patients with celiac disease, especially those with suspected complicated disease [karger.com]

A thorough workup of the patient should also be done, with at least a chest radiograph, CBC count, and liver panel, but also other imaging directed by the patient’s symptoms. [emedicine.medscape.com]

• Colitis

  Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases. [books.google.com]

  Ulcerative colitis and Crohn's disease generally require long-term medical care. [ariahealth.org]

  Vascular disease [ edit ] Ischemic enteritis is uncommon compared to ischemic colitis due to the highly vascularised nature of the small intestine, [12] allowing for sufficient blood flow in most situations. [en.wikipedia.org]

  Diarrhea affected a small proportion of children with recessive dystrophic EB with changes of colitis in the majority of patients. [emedicine.medscape.com]

Incorporate the latest findings and improvements in care for liver disease patients —from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. [books.google.com]

[…] months after treatment. [en.wikipedia.org]

Most patients with IBD will not require surgery, a treatment typically reserved for those for whom drug therapy and other treatments have not been successful. [ariahealth.org]

Withdrawal of NSAID treatment usually allows the ulcer to heal. Treatment for H. pylori –induced ulcers are antibiotics and a proton pump inhibitor. [britannica.com]

However, the treatment of scurvy is simply food containing vitamin C. Therefore, the therapeutic challenge in scurvy is in identifying patients needing treatment. [emedicine.medscape.com]

[…] celiac disease diagnosed simultaneously with lymphoma in most patients Abdominal pain, often intestinal perforation, sometimes prodrome of refractory celiac disease accompanied by ulceration (ulcerative jejunitis - UJ) Prognostic factors Treatment and Prognosis [pathologyoutlines.com]

Occurrence and prognosis of extranodal lymphomas. Cancer 29 :252, 1972 Google Scholar 7. Novis, B.H.: Primary intestinal lymphoma in South Africa. Isr. J. Med. Sci. 15 :386, 1979 Google Scholar 8. [link.springer.com]

However, owing to the poor prognosis of glucagonomas, the outcome of this condition is also poor. [emedicine.medscape.com]

Diagnosis, management, and prognosis. J. Am. Acad. Dermatol. 64, 1027–1033 (2011). 59. Jaskowski, T. D. et al. IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis and pediatric celiac disease. J. Invest. [nature.com]

Primary T/NK-cell lymphomas of the intestine are associated with a poor prognosis and a high risk of bowel perforation. [6] – [8] However, rare cases of primary GI indolent lymphoproliferative disorders of CD8 and CD4 T-cell lineages have been described [journals.plos.org]

Higher frequency in areas with high prevalence of celiac disease (northern Europe) Monomorphic variant (type II EATL): 10% - 20% of cases of EATL, broader geographic distribution and sporadic occurrence in areas where celiac disease is rare (Asia) Etiology [pathologyoutlines.com]

Etiologies and predictors of diagnosis in nonresponsive celiac disease. Clin. Gastroenterol. Hepatol. 5, 445–450 (2007). 61. Ludvigsson, J. F., Lindelof, B., Zingone, F. & Ciacci, C. [nature.com]

Genetic susceptibility, anatomical abnormalities, medications, trauma, infectious etiologies and metabolic causes are the primary risk factors for pediatric pancreatitis. [omicsonline.org]

The etiology of indolent small intestinal CD4 T-cell lymphomas is unclear. Persistent antigenic stimulation as a consequence of an immune-mediated or infectious disorder is a possibility. [journals.plos.org]

The cutaneous findings can be categorized into four main groups based on etiology. [emedicine.medscape.com]

Epidemiological study by Ludvigsson et al. [ 5 ] has suggested that patients with celiac disease have a higher risk than the general population for the development of acute pancreatitis. [omicsonline.org]

Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics. Brain 126, 685–691 (2003). 70. Hadjivassiliou, M. et al. [nature.com]

[…] lymphoid cells, which are negative for CD56 Terminology Also called intestinal T cell lymphoma (with or without enteropathy), but many other T cell lymphomas can present with intestinal involvement ICD coding ICD-O: 9717 / 3 - intestinal T cell lymphoma Epidemiology [pathologyoutlines.com]

The Spectrum of Celiac Disease: Epidemiology, Clinical Aspects and Treatment. Medscape from Nat Rev GastroenterolHepatol. 2010;7(4):204-213. [On-line information]. Available online at through . Accessed November 2010. [labtestsonline.it]

Communicable Disease Epidemiology and Control: A Global Perspective. CABI. ISBN 9781845935054. External links [ edit ] [en.wikipedia.org]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management, Expert Consult Premium Edition - Enhanced Online Features. Elsevier Health Sciences. ISBN 978-1437727678. Webber, Roger (2009-01-01). [en.wikipedia.org]

[…] most cases, NAE is associated with hepatitis C infection, [72] although several cases have occurred in patients without hepatitis C. [73, 74] Overall, it is a rare entity, with one study showing a prevalence 1.7% in patients with hepatitis C. [75] The pathophysiology [emedicine.medscape.com]

When gluten is removed from the diet, symptoms improve, the small intestine begins to repair the existing damage, and further damage is prevented. [westchestergi.com]

"Radiation Enteropathy – Pathogenesis, Treatment, and Prevention". Nature Reviews. Gastroenterology & Hepatology. 11 (8): 470–479. doi : 10.1038/nrgastro.2014.46. ISSN 1759-5045. PMC 4346191. PMID 24686268. Gregg, null; Nassar, null (1999-04-01). [en.wikipedia.org]

200 mg p.o. b.i.d. may decrease symptoms of gastritis Ursodeoxycholic acid (Actigall) 1,000 mg daily may decrease symptoms of bile reflux gastritis Various antioxidants and Chinese herbs reported to be beneficial in patients with chronic gastritis Prevention [clinicaladvisor.com]

No special diet has been proven effective for preventing or treating Crohn's disease. Certain symptoms are sometimes made worse by milk, alcohol, hot spices, or fiber, but this may not be true for everyone. [ariahealth.org]

Proton pump inhibitors, such as omeprazole, lansoprazole, and rabeprozale, inhibit the ATPase enzyme inside the parietal cell and prevent acid secretion. [britannica.com]