RESULTS: Couple 1: A 35-year-old man presented with "dark spots" in his right eye. He reported no recent steroid use. Visual acuity at presentation was 20/30 in the right eye and 20/20 in the left eye. [ncbi.nlm.nih.gov]

• Miosis

  These drugs are FDA-approved for management of ocular surface allergies, intraoperative pupillary miosis, pain, and anterior-segment inflammation following cataract surgery. [retinalphysician.com]

• Small Eyes

  CONCLUSION: Although uncommon, central serous chorioretinopathy can occur in anatomically small eyes after trabeculectomy surgery. [ncbi.nlm.nih.gov]

• Recurrent Rhinitis

  A detailed history taking revealed the patient was using 0.1% dexamethasone eye drops nasally for recurrent rhinitis for few days prior to each episode of CSC. [ncbi.nlm.nih.gov]

• Throbbing Headache

  The patient presented with a complaint of throbbing headache and blurry vision in left eye. The patient was diagnosed with diabetes mellitus 1 year previous to the event. On examination, uncorrected visual acuity was 20/20 OD, 20/200 OS. [ncbi.nlm.nih.gov]

• Electroretinogram Abnormal

  Multifocal electroretinogram abnormalities persist following resolution of central serous chorioretinopathy. Arch Ophthalmol. 2000 Sep. 118(9):1211-5. [Medline]. Lai TY, Chan WM, Li H, Lai RY, Liu DT, Lam DS. [emedicine.com]

Spironolactone treatment resolved the CSC. After the patient discontinued treatment, it returned. After returning to daily treatment, the CSC again resolved. CONCLUSION: Spironolactone was an effective treatment of CSC in this case. [ncbi.nlm.nih.gov]

Key results The studies considered a wide range of treatments. As a result, there were not enough studies of any one treatment to provide good evidence of treatment effects. In general, no significant side effects were noted. [doi.org]

Central serous chorioretinopathy can occur in the third trimester of pregnancy and generally has a benign course and good prognosis. Our patient ended up with significant and permanent visual impairment in one eye. [ncbi.nlm.nih.gov]

Abstract Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology with no specific histological features. [ncbi.nlm.nih.gov]

[…] for the prevention and treatment of cystoid macular edema. 12 Nevertheless, there have been several placebo-controlled studies, comparative studies, and case reports showing the safety and efficacy of topical NSAIDS in the treatment of CME of varied etiologies [retinalphysician.com]

The aim of this review is to recapitulate the clinical understanding of CSCR, with an emphasis on the most recent findings on epidemiology, risk factors, clinical and imaging diagnosis, and treatments options. [ncbi.nlm.nih.gov]

Central serous chorioretinopathy: a review of epidemiology and pathophysiology. Clin Experiment Ophthalmol. 2012 Jul 12. [Medline]. Kitzmann AS, Pulido JS, Diehl NN, Hodge DO, Burke JP. [emedicine.com]

As factors related to CSC, season and temperature might influence the pathophysiology of CSC. 2018 S. Karger AG, Basel. [ncbi.nlm.nih.gov]

Reduction in glucocorticoid combined with the use of immunosuppressive agents is one option for preventing a deterioration in atypical severe CSC while still controlling SLE. [ncbi.nlm.nih.gov]

None of the formulations mentioned are FDA-approved for the prevention and treatment of cystoid macular edema. 12 Nevertheless, there have been several placebo-controlled studies, comparative studies, and case reports showing the safety and efficacy of [retinalphysician.com]