Late cortical cerebellar atrophy (LCCA) is a neurodegenerative disease which presents with slowly progressive cerebellar ataxia as a prominent symptom and is characterized neuropathologically by a limited main lesion to the cerebellar cortex and inferior [ncbi.nlm.nih.gov]

• MRI Scan showing Cerebellar Atrophy

  Neurological examination showed moderate to severe weakness in distal muscles of all extremities, marked cerebellar sign and steppage gait. Muscle biopsy resulted in myopathic changes with rimmed vacuoles. Brain MRI scan showed cerebellar atrophy. [ncbi.nlm.nih.gov]

CONCLUSION: The transplantation of in vitro cultured neural stem cell is a feasible and effective treatment for inherited CA, but the long term effectiveness need to be taken in consideration. [ncbi.nlm.nih.gov]

Treatment Treatment Options: No treatment has been reported. [disorders.eyes.arizona.edu]

Cerebellar Atrophy Prognosis Atrophy of any tissue means loss of cells. In brain tissue, atrophy describes a loss of neurons and the connections between them. [topclassactions.com]

Prognosis The long-term outlook for people with cerebellar degeneration varies depending on its underlying cause. x Prognosis The long-term outlook for people with cerebellar degeneration varies depending on its underlying cause. [ninds.nih.gov]

Please tell me the prognosis of this disease. anon293481 Post 4 My husband is a traumatic brain injury patient. His injury was brought about by a vehicular accident two years ago. He is only 55 years old. [wisegeekhealth.com]

Etiology The exact etiology of MSC-c is unknown while the presence of cytoplasmic aggregates of α-synuclein, primarily in the oligodendroglia, in combination with predominant neurodegeneration of the olivopontocerebellar structures are pathological hallmark [orpha.net]

Etiology Diffuse atrophy can result from a variety of causes: normal aging alcoholic cerebellar degeneration drugs, e.g. phenytoin cerebellar degeneration chronic temporal lobe epilepsy (independently from phenytoin use) 7 cerebellitis multisystem atrophy [radiopaedia.org]

CCA was defined as an SCA of unknown etiology with imaging evidence of isolated cerebellar atrophy. [movementdisorders.org]

Except for JCV infection, no other etiology was found to explain cerebellar disorders. [jcm.asm.org]

Keywords Adult Amnesia/diagnosis/epidemiology Atrophy Brain/anatomy & histology Cerebellar Diseases/epidemiology/pathology Cerebellum/pathology Epilepsy, Temporal Lobe diagnosis/pathology Female Functional Laterality Humans Incidence Magnetic Resonance [analyzedirect.com]

Summary Epidemiology MSA-c is observed predominantly in patients from Asia. [orpha.net]

[…] features Characterized clinically by ataxia and gait disturbances in the setting of chronic alcoholism Pathologic features include cerebellar atrophy affecting the anterior / superior vermis with a loss of Purkinje cells and corresponding Bergmann gliosis Epidemiology [pathologyoutlines.com]

"Epidemiology of Cerebellar Diseases and Therapeutic Approaches". Cerebellum. 17 (1): 4–11. doi:10.1007/s12311-017-0885-2. PMID 28940047. External links[edit] Classification D ICD-10: G32.81 [en.wikipedia.org]

"Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics." Brain 126(Pt 3): 685-91. Pittock SJ and others. Paraneoplastic antibodies coexist and predict cancer, not neurological syndrome. [dizziness-and-balance.com]

Author information 1 Clinical Genetics Department, Human Genetics and Genome Research Division, National Research Center, Cairo, 12311, Egypt. 2 INSERM UMR 1163, Laboratory of Molecular and Pathophysiological Bases of Cognitive Disorders, Paris, France [ncbi.nlm.nih.gov]

[…] features include cerebellar atrophy affecting the anterior / superior vermis with a loss of Purkinje cells and corresponding Bergmann gliosis Epidemiology Occurs in approximately 10% of alcoholic patients Sites Anterior / superior cerebellar vermis Pathophysiology [pathologyoutlines.com]

The neuropathology, pathophysiology and genetics of multiple system atrophy. Neuropathol Appl Neurobiol. 2012;38:4-24. PubMed Koeppen AH, Mazurkievicz JE. Friedreich Ataxia: Neuropathology Revised. J Neuropathol Exp Neurol 2013;72(2):78-90. [neuropathology-web.org]

[…] and body sway during the 2-week titration period as well as the 8-week reassessment. [31] Insulin-Like Growth Factor Insulin-like growth factor-1 (IGF-1) acts as a neuromodulator in the CNS. [32] Disturbances in CNS signaling pathways may produce the pathophysiological [movementdisorders.org]

Early diagnosis of NBD helps to initiate appropriate treatment, thereby modulating the course of the disease and preventing complications. [ncbi.nlm.nih.gov]

The aim is to treat the symptoms and prevent complications. [medlineplus.gov]

It helps prevent seizures that affect the entire brain (tonic-clonic seizures) as well as seizures that affect only one half or part of the brain (partial seizures). It is often used to prevent seizures during and after brain surgeries. [topclassactions.com]

Prevention Rescuing Loved Ones Who Wander Current Issue Issue Archive Online Only En Español Explore Further Healthy Living Discover Brain & Life articles and news about living healthy, safety, prevention, caregiving, and more. [brainandlife.org]

[…] laboratory abnormalities Radiology description Atrophy of the anterior / superior vermis Radiology images Images hosted on other servers: Marked diffuse cerebellar atrophy Prognostic factors Cerebellar damage remains even after abstinence from ethanol Prevention [pathologyoutlines.com]