Overall, leptomeningeal involvement at presentation was present in 70.4% of patients with ABRA or CAA-RI and in only 7.4% of patients with CAA (P   0.0001). [ncbi.nlm.nih.gov]

However, its presentation is varied; depending upon severity, it may not be diagnosed until autopsy. [ajnr.org]

• Pathologist

  Grading was performed by a single pathologist (J-P.G.V.) without knowledge of the brain from which the section derived. [stroke.ahajournals.org]

  Although known to pathologists for over a century, 4 5 CAA was not linked to clinical disease until as late as the 1960s when it was suggested to be a rare cause of intracerebral haemorrhage (ICH). 6–8 In recent years, CAA has been ‘rediscovered’ as a [jnnp.bmj.com]

• Painter

  Shinohara M 1, Murray ME 1, Frank RD 2, Shinohara M 1, DeTure M 1, Yamazaki Y 1, Tachibana M 1, Atagi Y 1, Davis MD 1, Liu CC 1, Zhao N 1, Painter MM 1, Petersen RC 3, Fryer JD 1, Crook JE 2, Dickson DW 1, Bu G 4, Kanekiyo T 5. [ncbi.nlm.nih.gov]

• Dysphasia

  Case 1 was a 67-year-old man reporting right-sided paroxysmal sensory episodes with Jacksonian progression, cheiro-oral symptoms, and motor dysphasia. [ncbi.nlm.nih.gov]

  Rigney L, Sebire D, Cordato D (2015) Acute dysphasia and reversible cognitive decline in a patient with probable cerebral amyloid angiopathy-related inflammation. Case Rep Neurol Med 2015: 189581. [omicsonline.org]

  CAA-related macrohemorrhage with associated subarachnoid hemorrhage in an 81-year-old man with acute dysphasia and agitation. Axial nonenhanced CT scan shows an irregular, 4 5-cm, left-sided frontoparietal cortical ICH. [doi.org]

• Generalized Seizure

  A 79-year-old woman was admitted to the Neurological Department after the occurrence of generalized seizures, the first in her life. On admission she was unconscious with right hemiparesis and deviation of eyes to the left. [ncbi.nlm.nih.gov]

• Communicating Hydrocephalus

  She entered in an apathetic state due to communicating hydrocephalus and a ventricle-peritoneal (V-P) shunt operation was performed. [ncbi.nlm.nih.gov]

• Sensory Seizure

  We report a clinical case series of 3 patients with cSAH associated with probable cerebral amyloid angiopathy (CAA) who presented with focal sensory seizures and responded well to corticosteroid treatment. [ncbi.nlm.nih.gov]

An extensive workup including HIV testing, CSF examination for infectious etiology including protein 14-3-3 and demylineating disease was negative. Paraneoplastic and autoimmune workup was also non-diagnostic. [elynsgroup.com]

Consultations The following consultations are useful: Neurologic evaluation for clinical evaluation, diagnostic workup, and management Neurosurgical consultation in cases of ICH Neuropsychological assessment for cognitive impairment CT and PET Scanning [emedicine.com]

During her admission in May 2014, she was admitted again with acute confusion, headache, and vomiting and was hospitalized for workup of her acute encephalopathy. MRI brain showed a new right temporo-parietal ICH with surrounding vasogenic edema. [innovationscns.com]

• Neurofibrillary Tangle

  We report findings from an autopsy of a male in his 40s who died of a brain stem hemorrhage associated with cerebral amyloid angiopathy (CAA), senile plaques (SPs) and neurofibrillary tangles (NFTs), which are histopathological changes associated with [ncbi.nlm.nih.gov]

  Some neuritic plaques, dystrophic neuritis and neurofibrillary tangles (NFT) were also seen in the cortical layers. The above histology suggested CAA with co-existing Alzheimer pathology. [neurologyindia.com]

• Ischemic Changes

  Furthermore, at sites of fibrinoid necrosis, there may be luminal narrowing, which can lead to ischemic change (, 4 ). [doi.org]

RESULTS: Among patients given systemic lytic treatment for stroke, those who have microhemorrhages tend to have a higher risk of treatment-associated brain hemorrhage. [ncbi.nlm.nih.gov]

This case reminds us early recognition of brain abscess formation at the site of intracerebral hemorrhage is very important for prompt and appropriate treatment to improve the overall prognosis. [ncbi.nlm.nih.gov]

Diagnosis - Cerebral Amyloid Angiopathy Prognosis - Cerebral Amyloid Angiopathy Not supplied. Treatment - Cerebral Amyloid Angiopathy Resources - Cerebral Amyloid Angiopathy [checkorphan.org]

Diagnosis and Prognosis: The diagnosis requires a multidisciplinary approach by neurologists and ophthalmologists. No treatment is available other than cataract surgery if necessary and most patients do not live beyond about the 5 th or 6 th decades. [disorders.eyes.arizona.edu]

Imaging and pathology findings suggested CAA as the main etiology of this presentation. This is a very rare case of CAA coexisting with aneurysmal subarachnoid hemorrhage. [ncbi.nlm.nih.gov]

Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Although the etiology of the white matter lesion was not specified, the lesion and symptoms improved with steroid pulse therapy. [jstage.jst.go.jp]

In this article, we aimed to present a systematic review of cerebral amyloid angiopathy related disorders with regard to their epidemiology, pathophysiology, clinical features, neuroimaging biomarkers, diagnosis criteria, and treatment. [ingentaconnect.com]

But he said there are no good epidemiological data to put an absolute number on it. [medpagetoday.com]

Epidemiology Occurrence in the United States The true incidence and prevalence of cerebral amyloid angiopathy (CAA) are hard to specify, as definite CAA is a pathologic diagnosis typically obtained postmortem. [emedicine.com]

Its precise pathophysiology remains uncertain and we currently have limited evidence on which immunosuppressive agents are the most effective in its treatment. [ncbi.nlm.nih.gov]

In this review, we summarize the risks linked to CAA with respect to the treatment and prevention of stroke. [ncbi.nlm.nih.gov]

Causes - Cerebral Amyloid Angiopathy Prevention - Cerebral Amyloid Angiopathy Not supplied. Diagnosis - Cerebral Amyloid Angiopathy Prognosis - Cerebral Amyloid Angiopathy Not supplied. [checkorphan.org]