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Cerebral Neoplasm


Presentation

  • As such, at the present time, we can only assume that these peaks are representative of glutamine and glutamate.[ajnr.org]
  • The authors' experience with DT imaging indicates that anatomically intact fibers may be present in abnormal-appearing areas of the brain.[ncbi.nlm.nih.gov]
  • Here, we report a case of a 12-year old female patient who presented in outpatient clinic with a short period history of headache and seizures. A CT scan showed a large right sided frontal space occupying lesion with areas of calcification.[ijp.iranpath.org]
  • Any middle-aged or elderly patients presenting with a first seizure should have CNS tumor high in the differential diagnosis. Patients with a brain tumor may present with acute neurologic changes mimicking those associated with stroke.[emedicine.medscape.com]
  • This toxicity presents risks for bleeding, anemia, and infection.[childhoodbraintumor.org]
Gagging
  • […] reflex, ability to swallow) -teach pt w/decreased gag response to direct food/fluids toward unaffected side, sit upright, semisoft diet, & have suction readily available -neuro checks -VS -space interventions to prevent rapid increase in ICP -reorient[quizlet.com]

Workup

  • The patient had an unremarkable collagen vascular workup. There was also no evidence of an infectious or drug-induced cause of vasculitis.[ajnr.org]
  • […] include incompatibility with certain medical equipment, longer imaging times (increased risk of motion artifact), and poor visualization of the subarachnoid space Neither CT nor MRI can be used to differentiate tumor recurrence from radionecrosis See Workup[emedicine.medscape.com]
  • Any adult who has a recent onset of seizures, particularly focal seizures, is considered a tumor suspect until adequate neurologic workup proves otherwise. Specific Tumor Types There are many types of tumors that develop intracranially.[dartmouth.edu]

Treatment

  • Research interests include the evaluation of treatment for alcohol problems in specialist and generalist settings and, in particular, treatment for addicted healthcare professionals.[books.google.com]
  • Rehab Management: Treatment addresses both the effects of the tumor and the side effects of cancer therapies (surgery, chemotherapy, and radiation).[aapmr.org]
  • Treatment with dexamethasone and cyclophosphamide was instituted, and her symptoms improved markedly within 3 weeks.[ajnr.org]
  • Download full chapter on “Treatment Options” from Frankly Speaking Treatment Center Options Choosing a treatment center can be difficult.[braintumor.org]
  • […] for diagnosis and treatment.[hopkinsmedicine.org]

Prognosis

  • Prognosis 5-year survival: 40-50% 10-year survival: 47-68% Better prognosis: Young age Infratentorial Gross total excision Low-grade histology 52. II.[slideshare.net]
  • Your neurosurgeon will be able to give you a more clear idea of prognosis when the final diagnosis has been made.[uhs.nhs.uk]
  • Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options for primary brain and spinal cord tumors depend on the following: The type and grade of the tumor.[my.clevelandclinic.org]
  • In this section: Definition Symptoms Diagnosis Treatment Prognosis MRI image showing a typical meningioma tumor A meningioma is a tumor that arises from a layer of tissue (the meninges) that covers the brain and spine.[neurosurgery.ucla.edu]
  • The prognosis is highly variable: cerebellar astrocytoma has a good prognosis, pontine glioma has a bad prognosis because of location.[dartmouth.edu]

Etiology

  • Although the cause of this disorder is unclear, a viral etiology, as well as an association with lymphoma, has been reported ( 2, 3 ).[ajnr.org]
  • Clinical Clues to Nonmalignant Brain Lesions Clinical clues Suggested etiology Abnormalities found on more extensive imaging that are suggestive of an etiology Cysticercosis, fungal infections, sarcoidosis, tuberculosis Chronic fever; recent dental procedure[aafp.org]
  • Headaches in a pediatric emergency department: etiology, imaging, and treatment. Headache. 2000;40:25-29. [34] Burton LJ, Quinn B, Pratt-Cheney JL, et al. Headache etiology in a pediatric emergency department. Pediatr Emerg Care. 1997;13:1-4.[bestpractice.bmj.com]
  • Etiology of Meningioma 56. Progesterone receptors - Expressed in 80% of women with meningiomas - Expressed in 40% of men with meningiomas 57.[slideshare.net]
  • In some instances, however, the symptoms are specific to the etiology. Hemorrhage, which can be parenchymal or extra-axial is the most common cause of intracranial mass lesions and is discussed in Chapter 27.[dartmouth.edu]

Epidemiology

  • The descriptive epidemiology of craniopharyngiomas. J Neurosurg. 1998;89:547-551. [16] Haupt R, Magnani C, Pavanello M, et al. Epidemiological aspects of craniopharyngioma.[bestpractice.bmj.com]
  • Epidemiology of brain tumors. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016:chap 71. National Cancer Institute website.[medlineplus.gov]
  • Epidemiology [ 1 ] Primary brain tumours represent about 2% of all tumours diagnosed in the UK. It has been estimated that the lifetime risk of developing brain and other central nervous system (CNS) cancer is 1 in 77 for men and women in the UK.[patient.info]
  • Evaluation of epidemiologic evidence for primary adult brain tumor risk factors using evidence-based medicine. Prog Neurol Surg. 2006;19:54–79. 6. Ostrom QT, et al.[aafp.org]
Sex distribution
Age distribution

Prevention

  • A variety of medications are available to improve neurologic function, limit nausea, manage pain, prevent blood clots, and minimize seizures.[aapmr.org]
  • In general, chemotherapy can make it possible to delay, decrease or eliminate the radiation normally given to the entire brain and spine in an attempt to prevent relapse distant from the site of the primary tumor.[childhoodbraintumor.org]
  • Collaborative initiatives with the UChicago Medicine Comprehensive Cancer Center aim to substantially advance the treatment and prevention of brain and spinal cord metastases.[uchospitals.edu]
  • […] shrink the tumor or prevent the tumor from growing back Comfort measures, safety measures, physical therapy, occupational therapy, and other such steps may be required to improve quality of life.[medlineplus.gov]
  • Michael Lim, the Center strives to improve the diagnosis and treatment of patients with metastatic brain tumors while furthering research in their prevention and treatment.[hopkinsmedicine.org]

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