Presentation
Superior displacement of the right globe was present with normal visual acuity and no restricted eye movements. Obliteration of the nasolabial fold was present. [ncbi.nlm.nih.gov]
Entire Body System
- Sulfur Granules
Actinomycosis, a chronic suppurative bacterial infection characterized by draining sinuses that discharge "sulfur granules," can mimic numerous other infectious and noninfectious conditions. [ncbi.nlm.nih.gov]
On surgical pathology, actinomycosis is characterized by sulfur granules (Figure 1). These are composed of bacteria cemented together by a polysaccharide-protein complex and calcium phosphate. Grossly, these sulfur granules appear yellow. [path.upmc.edu]
Subsequently, areas of softening appear and develop into sinuses and fistulas that discharge the characteristic sulfur granules. [msdmanuals.com]
granules is seen in approximately 40% of cases. [2] Our patient had palpable mass with regional lymphadenopathy but no sinus tracts or sulfur granules. [e-ijd.org]
- Fever
Pelvic actinomycosis affects the women's pelvic area and may cause lower abdominal pain, fever, and bleeding between menstrual periods. [healthcentral.com]
The individual may have: abscesses persistent fever pain diarrhea or constipation pus that appears through the skin The type of infection can spread. [medicalnewstoday.com]
Actinomycosis of the pelvis will result in a mild fever (less than 100.4 degrees Fahrenheit or 38 degrees Celsius), fatigue and a loss of appetite. [wikihow.com]
It usually presents with a history of prolonged use (>2 years) and symptoms of fever, vaginal discharge, pelvic or abdominal pain, and weight loss. [patient.info]
Fever and other symptoms of systemic infection are sometimes present. Actinomycosis around the jaw can cause trismus (prolonged spasm of the jaw muscles). [dermnetnz.org]
- Malaise
Symptoms may include pelvic pain, leukorrhea, menorrhagia, and amenorrhea, associated with fever, malaise, weakness, and weight loss, in any combination. [antimicrobe.org]
Jaw & Teeth
- Trismus
Actinomycosis around the jaw can cause trismus (prolonged spasm of the jaw muscles). Lymph nodes are not usually enlarged and there is generally little pain, unless adjacent structures are compressed. [dermnetnz.org]
[6] and tender or non-tender woody hard multiple nodular lesions, usually situated at the angle of the jaw, multiple abscesses and sinuses that open onto the cheek, sulfur granules in the exudates, typical absence of lymphadenopathy, with or without trismus [jiaomr.in]
Tenderness, trismus and expansive hardness of the surrounding tissues were noted. There were no palpable lymph nodes. [bmcinfectdis.biomedcentral.com]
Trismus may be prominent early in the patient's course; however, cervical lymphadenopathy is uncommon. Direct extension may involve the tongue, sinuses, and meninges and rarely, contribute to periostitis or osteomyelitis of the mandible ( 74 ). [antimicrobe.org]
Face, Head & Neck
- Neck Mass
We report a case of cervicofacial actinomycosis with paravertebral extension in a 60-year-old man who presented with recurrent neck masses. Diagnosis was confirmed on culture and histology of pus and debris obtained from surgical drainage. [ncbi.nlm.nih.gov]
Pediatric Cervicofacial Actinomycosis: An Unusual Cause of Head and Neck Masses. J Pediatric Infect Dis Soc. 2014 Jun. 3 (2):e15-9. [Medline]. Kutluhan A, Salviz M, Yalçiner G, Kandemir O, Yesil C. [emedicine.medscape.com]
Workup
If workups for tuberculosis and fungal infections are negative, a high degree of suspicion is needed to diagnose actinomycosis correctly. Actinomycosis frequently imitates a neoplastic process when faced with an ill-defined and fixed mass. [woundsresearch.com]
[…] bacilli AM: Actinomycosis HIV: Human immunodeficiency virus Declarations Acknowledgements We are grateful to the laboratory and clinical staff of the Banso Baptist Hospital and Bamenda Regional Hospital for their incessant collaboration in the laboratory workup [bmcinfectdis.biomedcentral.com]
Treatment
Hence, early diagnosis and appropriate treatment is mandatory to reduce morbidity. [ncbi.nlm.nih.gov]
Prognosis
The book starts by describing the etiology, microscopical appearance, production of odor, epidemiology and pathogenesis, direction of peripheral spreading, differential and clinical diagnosis, prognosis, and treatment of antinomycosis. [books.google.com]
The prognosis for treated infection is excellent. [ncbi.nlm.nih.gov]
What is the Prognosis of Cervicofacial Actinomycosis? (Outcomes/Resolutions) The prognosis of Cervicofacial Actinomycosis is determined by the overall health of the affected individual. [dovemed.com]
The prognosis for treated infection is excellent. (PDF emailed within 0-6 h: $19.90) Accession: 004066693 Download citation: RIS BibTeX Text PMID: 15847718 DOI: 10.1007/s11908-005-0030-0 Diagnosis of cervicofacial actinomycosis. [eurekamag.com]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
The book starts by describing the etiology, microscopical appearance, production of odor, epidemiology and pathogenesis, direction of peripheral spreading, differential and clinical diagnosis, prognosis, and treatment of antinomycosis. [books.google.com]
Relevant procedures necessary for reliably diagnosing actinomycosis are discussed, with details of their complex etiology. PubMed CrossRef Google Scholar 5. [link.springer.com]
The etiology of this gender disparity is not known, but it is hypothesized to be due to differences in dental hygiene habits between male and females, as well as due to increased incidence of oral trauma in male as compared to female patients. [path.upmc.edu]
Epidemiology
The book starts by describing the etiology, microscopical appearance, production of odor, epidemiology and pathogenesis, direction of peripheral spreading, differential and clinical diagnosis, prognosis, and treatment of antinomycosis. [books.google.com]
Patient Population: Prevalence and Epidemiology Knee // Shoulder & Elbow // Hip // Spine // Foot & Ankle // Hand & Wrist Fragility Fractures: Diagnosis and Treatment Shoulder & Elbow The Characteristics of Surgeons Performing Total Shoulder Arthroplasty [mdedge.com]
There is little characteristic epidemiology for actinomycosis in general. Pelvic disease is much more likely when an intrauterine device (IUD) is in place. [infectiousdiseaseadvisor.com]
Cervico-facial actinomycosis: epidemiological and clinical comments. Am J Infect Dis 2008;3:204-8. 3. Anees A, Yaseen M, Sherwani R, Khan MA. Extensive lymphangioma circumscriptum - A case report. J Indian Acad Clin Med 2006;7:55-7. 4. [e-ijd.org]
Pathophysiology
The authors highlight the possible pathophysiology of this condition. It is suggested that clinicians be aware of the various modes of presentation and natural history of the disease to facilitate prompt diagnosis and appropriate treatment. [ncbi.nlm.nih.gov]
Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination findings, diagnosis, treatment and prognosis, immunity, prevention, and public health [books.google.com]
Pathophysiology Actinomyces species that cause human disease are not found in nature but are normal flora of the oropharynx, GI tract, and female genital tract. [emedicine.medscape.com]
Prevention
Health care professionals’ knowledge about the disease is crucial in a way to promote its prevention, early diagnosis and proper treatment. [alicia.concytec.gob.pe]
Sellers, Emory University, via the Public Health Image Library of the Centers for Disease Control and Prevention. [merckmanuals.com]
Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination findings, diagnosis, treatment and prognosis, immunity, prevention, and public health [books.google.com]
Prevention The best prevention is to maintain good dental hygiene. Resources PERIODICALS Sudhaker, Selvin S., and John J. Rose. "Short-term Treatment of Actinomycosis: two Cases and a Review." Clinical Infectious Diseases (February 1, 2004): 444-448. [encyclopedia.com]
The following tips may be helpful in the prevention of Cervicofacial Actinomycosis: Practicing proper dental hygiene: Maintaining proper dental hygiene always, and particularly, following a dental procedure, surgery, or tooth extraction Educating oneself [dovemed.com]