Presentation
"Chancroid Clinical Presentation". News-Medical. https://www.news-medical.net/health/Chancroid-Clinical-Presentation.aspx. (accessed November 03, 2022). Harvard Meštrović, Tomislav. 2019. Chancroid Clinical Presentation. [news-medical.net]
Special treatment situations Special considerations Seek specialist advice before treating any complicated presentation. Follow up Will be provided by specialist service. Test of Cure (TOC) Not required. [sti.guidelines.org.au]
Case presentation A 13-year-old girl presented with acute ulcers with pain and inflammation in the labia majora that prevented ambulation and was also associated with fever. [ncbi.nlm.nih.gov]
A presentation of systemic toxicity, a productive cough, and bloody sputum suggests a large differential diagnosis. [tripdatabase.com]
Genetic diseases can present with chronic ulceration of vulval and perianal skin. Epidermolysis bullosa is a group of disorders that present with blistering in childhood. [dermnetnz.org]
Entire Body System
- Chills
The lesions tend to be more extensive, producing multiple lesions that may be accompanied by systemic manifestations such as fever and chills. Reports of rapidly aggressive lesions have been noted by some clinicians. [apps.who.int]
Additional symptoms include fever and chills, myalgia, arthralgia and perianal edema. In syphilis the vulva is covered with typical lesions called chancres which develop 10-90 day after exposure to the bacteria. These lesions are painless. [ic.steadyhealth.com]
HIV Symptoms Flu-like symptoms 1 to 2 months after first infection, including like swollen lymph nodes, fever, and headaches Chills Rash Night sweats Muscle Aches Sore throat Swollen lymph nodes Mouth ulcers AIDS Symptoms Rapid weight loss Recurring fever [onhealth.com]
The person may also have fever, headaches, body aches, chills, and swollen lymph nodes near the genitals. The next infections are usually not as bad as the first one. To stop the spread of herpes, people should not have sex when they have a sore. [en.hesperian.org]
- Shivering
I've never had this before and the thought of ever having sex again literally sends shivers up my spine. My partner said that he hasn't noticed any symptoms, but I've advised him that it's important that he gets checked as soon as possible. [medhelp.org]
Gastrointestinal
- Rectal Bleeding
Others may not experience sores, but may develop symptoms such as vaginal discharge or rectal bleeding. How is chancroid treated? Chancroid is treated with antibiotics. If treatment is successful, the ulcers usually begin to improve within a week. [irishhealth.com]
Women generally have less specific symptoms such as painful urination or pain on passing bowel motions (defaecation), vaginal discharge, painful sexual intercourse ( dyspareunia ) and rectal bleeding. [dermnetnz.org]
Alternatively, women may not have any external sores but may experience painful urination, intercourse, and/or bowel movements and may have a vaginal discharge or rectal bleeding. [encyclopedia.com]
Women may be less likely to get the sores; instead, their symptoms may include painful urination or defecation, painful intercourse, rectal bleeding, or vaginal discharge. [std-gov.org]
Skin
- Papule
One colony-forming unit (cfu) of H. ducreyi results in papule formation in 50% of individuals. 90% develop papule with 100 cfu ( 3 ). [unboundmedicine.com]
Papule or ulcer Persistent, painful, beefy- Red Papule s or ulcers onset 2-3 months after exposure Necrosis or sclerosis may occur Behcet Sydrome Ulcer Recurrent oral ( Aphthous Ulcer ) and Genital Ulcers Genital Ulcers scar in more than half of cases [fpnotebook.com]
Transient chancroid is a term for a tiny papule that is often overlooked, but characteristic lymphadenopathy is present. [news-medical.net]
The primary infection is characterized by one or more ulcers of the vulva or cervix that are usually preceded by a papule.( 2) Secondary infection may make these lesions quite inflamed and tender, although they may also be non-tender. [encognitive.com]
The first sign of chancroid is a small, red papule that occurs within three to seven days following exposure to the bacteria, but may take up to one month. Usually within one day, the papule becomes an ulcer. [medical-dictionary.thefreedictionary.com]
- Erythema
Buboes are usually located only on one side of the body and coupled with erythema of the superjacent skin. They sometimes spontaneously rupture and form inguinal sinuses. [news-medical.net]
The ulcer is extremely painful and surrounded by erythema, and it is often foul smelling. Lesions can be solitary or by autoinoculation form multiple lesions that can coalesce into "kissing" lesions or giant ulcers. [kelmacmedical.us]
Erythema multiforme is an acute or recurrent reactive condition. Erythema multiforme major can cause very painful vulval ulceration, usually associated with oral ulceration and target lesions on the distal extremities. [dermnetnz.org]
Behçet disease includes recurrent oral and genital ulceration with multiorgan symptoms (erythema nodosum, uveitis, vasculitis, arthritis, etc). [ncbi.nlm.nih.gov]
- Skin Lesion
Some less common causes include skin conditions such as lichen planus, lichen sclerosis, seborrheic dermatitis, and vitiligo. Benign (non-cancerous) cysts can also be causes of genital skin lesions or sores. Ask a dermatologist today! [idoc24.com]
This organ can be affected by various changes that affect either the skin or the mucous membrane. Sometimes both of these surfaces are covered with different skin lesions. Vulvar lesions range from benign growths to malignant tumors. [ic.steadyhealth.com]
A review of systems should include: Systemic symptoms (fever, malaise, headache, GI symptoms, respiratory symptoms, myalgia) Oral ulcers, skin lesions, ocular symptoms. A family history of autoimmune disorders should be determined. [rch.org.au]
[…] and skin barriers, the presence of cells with up-regulated HIV-1 co-receptors in H ducreyi –infected lesions provides an environment that facilitates the acquisition of HIV-1 infection. [emedicine.medscape.com]
Broad-spectrum antibiotics to cover skin flora should be considered. [ncbi.nlm.nih.gov]
Urogenital
- Dyspareunia
Causes of Dyspareunia Are Multiple The causes of dyspareunia, as with most sexual dysfunction, can be classified as either organic (physical or medical factors such as illness, injury or drug effects) or psychosocial (including psychological, interpersonal [worldoffemale.com]
[…] develop Buboes appear in about 50% of male patients The foreskin may swell The ulcers usually are found in: the prepuce near the frenulum coronal sulcus glans Rectal sores may bleed and or cause pain when defecating In women Buboes are uncommon in women Dyspareunia [mobieg.co.za]
Women generally have less specific symptoms such as painful urination or pain on passing bowel motions (defaecation), vaginal discharge, painful sexual intercourse ( dyspareunia ) and rectal bleeding. [dermnetnz.org]
Even though in some cases vulvar lesions may go undetected because they are asymptomatic, it is a general rule that a woman must have at least one symptom such as pruritus (itchy sensation), dysuria (painful urination) or dyspareunia (painful sexual intercourse [ic.steadyhealth.com]
There is only a single ulcer in most infected men and appears in coronal sulcus of the uncircumcised glans penis, whereas women frequently have four or more ulcers, characterized by dysuria (pain with urination) and dyspareunia (pain with intercourse) [zeenews.india.com]
- Urethral Discharge
Urethritis (urethral discharge) may be seen in male patients and cervicitis (leading to vaginal discharge) may be present in female patients. [cancertherapyadvisor.com]
Gonorrhea Symptoms Burning during urination Vaginal or urethral discharge Pelvic pain in women Men may experience swelling of the testes and discharge from the penis In some cases, the symptoms are mild and the condition is mistaken for a urinary tract [onhealth.com]
Nongonococcal Urethritis (NGU) Nongonococcal urethritis (NGU) is an urethral inflammation that is not caused by Neisseria gonorrhoeae. [courses.lumenlearning.com]
- Vulvar Pain
Chancroid is a painful vulvar ulcer. Trichomonas can sometimes be associated with vulvar pain. Dr. Lonky: What terminology do we use when we discuss vulvar pain? Dr. [mdedge.com]
Workup
Hence, it is important to know the workup and the thorough differential diagnosis to establish its diagnosis. [ncbi.nlm.nih.gov]
Microbiology
- Candida
We present a case of chancroid in patient with Candida glabrata vaginitis. [ejgm.co.uk]
Vulvar eczema Infection due to Candida and yeast, tinea cruris etc. [news-medical.net]
Other less frequent but more resistant to treatment candida may be Candida krusei, Candida glabrata, or Candida tropicalis. [intechopen.com]
Most are due to Candida albicans. Yeast appears in 15 to 20 percent of nonpregnant and 20 to 40 percent of pregnant women. [cedars-sinai.edu]
The type of yeast most often associated with yeast infections is called candida. What are the symptoms? Yeast infections are accompanied by a thicker, whiter, clumpier discharge that’s usually odorless. [refinery29.com]
Treatment
Principal Treatment Options Situation Recommended Alternative Uncomplicated infection Azithromycin 1g PO, stat OR Ceftriaxone 500mg in 2mL of 1% lignocaine IMI, stat OR Ciprofloxacin 500mg PO, BD for 3 days Alternative regimens are not recommended Treatment [sti.guidelines.org.au]
Condyloma Lata Treatment Same as Primary Syphilis www.freelivedoctor.com 23. [slideshare.net]
The book gives clinicians the necessary background information to educate patients on how these diseases are transmitted and acquired, what treatment options are available, what to expect from treatment, and how to prevent reinfection. [books.google.com]
What is the treatment for syphilis? For detailed treatment recommendations, please refer to the 2021 CDC STI Treatment Guidelines. [cdc.gov]
Low enough levels confirm adequate treatment. [medicalnewstoday.com]
Prognosis
Prognosis - Chancroid Prognosis is excellent with proper treatment. Treating sexual contacts of affected individual helps break cycle of infection. Resources - Chancroid Not supplied. [checkorphan.org]
Advances in the recognition of potentially confusing benign conditions, prognosis and staging update the pathology of squamous and adenocarcinoma in these organs. [books.google.de]
Etiology
Disease-oriented chapters include etiology, differential diagnosis, history, physical examination, laboratory and imaging studies, treatment, and special considerations during pregnancy. [books.google.com]
[…] superimposed Fusobacterium infection is present Do not confuse with chancre, a lesion typical of infection with syphilis Epidemiology Mainly in developing countries, particularly Africa, Asia and Latin America Associated with commercial sex workers Etiology [pathologyoutlines.com]
More common in Sub-Saharan Africa Southeast Asia Latin America Etiology and Pathophysiology Haemophilus ducreyi enters through abraded skin during sexual activity, attaching to susceptible cells. [unboundmedicine.com]
Epidemiology
Showing 1-10 of 51 references Sex, soap and antibiotics : the case for chancroid eradication Changing aetiology of genital ulcer disease ( GUD ) in STD clinic attenders with a rising HIV prevalence Epidemiological, clinical and microbiological features [pdfs.semanticscholar.org]
Lippincott Williams & Wilkins, 2003 - 275 من الصفحات This concise handbook provides the essential information that physicians and nurse practitioners need on the epidemiology, microbiology, diagnosis, management, and prevention of sexually transmitted [books.google.com]
[…] chancroid: may extend rapidly and be associated with ruptured inguinal abscess Phagedenic chancroid: may destroy external genitalia if superimposed Fusobacterium infection is present Do not confuse with chancre, a lesion typical of infection with syphilis Epidemiology [pathologyoutlines.com]
[…] sporadic cases, often misdiagnosed as genital herpes. 9, 10 The distinct decrease in prevalence has followed the introduction by the World Health Organization (WHO) of syndromic management for treating genital ulcer disease. 4 Nevertheless, the global epidemiology [accessmedicine.mhmedical.com]
Genital Ulcer Disease Management Herpes Simplex Management • Treat for syphilis, and, depending upon local epidemiology, either chancroid, granuloma inguinale or lymphogranuloma venereum • Aspirate any fluctuant glands (surgical incision should be avoided [apps.who.int]
Pathophysiology
More common in Sub-Saharan Africa Southeast Asia Latin America Etiology and Pathophysiology Haemophilus ducreyi enters through abraded skin during sexual activity, attaching to susceptible cells. [unboundmedicine.com]
Background, Pathophysiology, Epidemiology. N.p., 09 Feb. 2017. Web. 16 Apr. 2017. Last Updated: 16 January 2018. [soc.ucsb.edu]
See Pathophysiology. Chancroid is closely associated with prostitution. H ducreyi can survive only in subgroups of the population with a sufficient turnover of sex partners. [emedicine.medscape.com]
The pathophysiological mechanism of ulcer in these cases is unknown. [ncbi.nlm.nih.gov]
[…] the glans [ ] Placement of a preputial bead Erotic dancing [ ] P lasmodium falciparum infection [ ] Contact dermatitis (eg, from the application of celandine juice to the foreskin [ ] ) Haemophilus ducreyi infection ( chancroid ) [ ] Previous Next: Pathophysiology [tripdatabase.com]
Prevention
Some researchers have speculated that these products, designed for use prior to sexual intercourse to prevent infection, might also be used for postcoital or emergency STD prevention. [un.org]
Lippincott Williams & Wilkins, 2003 - 275 من الصفحات This concise handbook provides the essential information that physicians and nurse practitioners need on the epidemiology, microbiology, diagnosis, management, and prevention of sexually transmitted [books.google.com]
C 15, 16 Prevention Avoiding sexual intercourse during outbreaks does not prevent transmission of HSV infection. [aafp.org]
HIV prevention through early detection and treatment of other sexually transmitted diseases–United States. Recommendations of the Advisory Committee for HIV and STD prevention. MMWR Recomm Rep, 1998. 47(RR-12): p. 1-24. 8. [cdc.gov]