Presentation
"Chancroid Clinical Presentation". News-Medical. https://www.news-medical.net/health/Chancroid-Clinical-Presentation.aspx. (accessed November 03, 2022). Harvard Meštrović, Tomislav. 2019. Chancroid Clinical Presentation. [news-medical.net]
Special treatment situations Special considerations Seek specialist advice before treating any complicated presentation. Follow up Will be provided by specialist service. Test of Cure (TOC) Not required. [sti.guidelines.org.au]
Case presentation A 13-year-old girl presented with acute ulcers with pain and inflammation in the labia majora that prevented ambulation and was also associated with fever. [ncbi.nlm.nih.gov]
A presentation of systemic toxicity, a productive cough, and bloody sputum suggests a large differential diagnosis. [tripdatabase.com]
Genetic diseases can present with chronic ulceration of vulval and perianal skin. Epidermolysis bullosa is a group of disorders that present with blistering in childhood. [dermnetnz.org]
Entire Body System
- Pain
Cause Haemophilus ducreyi Clinical presentation Male Female Symptoms Multiple, deep, painful genital ulcers with ragged undermined edges typically occur on the prepuce and in the coronal sulcus Multiple, deep, painful genital ulcers with ragged undermined [sti.guidelines.org.au]
pain: pain related to a specific disorder. [mdedge.com]
Lymph Nodes In 50% of cases with chancroid, the inguinal lymph nodes, situated between the thighs and the abdomen on either side, may become infected, producing swollen and painful lumps. [gynaeonline.com]
Even though in some cases vulvar lesions may go undetected because they are asymptomatic, it is a general rule that a woman must have at least one symptom such as pruritus (itchy sensation), dysuria (painful urination) or dyspareunia (painful sexual intercourse [ic.steadyhealth.com]
Glands on one side become enlarged, hard, painful and fuse together to form a bubo (BEW-bo), an inflammation and swelling of one or more lymph nodes with overlying red skin. Surgical drainage of the bubo may be necessary to relieve pain. [dph.illinois.gov]
- Asymptomatic
Bacterial Infections Gonorrhea may be asymptomatic, but there may be vulvar pruritus, burning sensation, pain and patients basically report the presence of green-yellow discharge. [ic.steadyhealth.com]
The outbreak was terminated by intensive surveillance efforts, contact tracing, and antimicrobial treatment of both symptomatic and asymptomatic sex partners. [cdc.gov]
[…] reduced risk of contracting chancroid. 11 Several studies in Africa show that chancroid ulcer was an important risk factor for the heterosexual spread of HIV. 12, 13 In West Africa, it has been shown that 2% of female sex workers carry the organism asymptomatically [accessmedicine.mhmedical.com]
Antiviral medications can shorten the duration of outbreaks and, if taken daily, can reduce recurrences and decrease asymptomatic shedding. Usually multiple, grouped vesicles that evolve into ulcers; typically painful. [cancertherapyadvisor.com]
However, it's important to remember that some people, usually women, are asymptomatic. [dph.illinois.gov]
- Constitutional Symptom
With the first clinical episode, constitutional symptoms are more likely to be present (fever, headache, myalgias, and malaise). [cancertherapyadvisor.com]
symptoms may occur in herpes simplex, secondary syphilis, LGV, or systemic lupus erythematosus. [dermnetnz.org]
symptoms and regional lymphadenopathy. 3 Figure 1. [aafp.org]
- Inguinal Mass
Inguinal lymphadenopathy is extensive and may split the inguinal mass into halves separated by Poupart's ligament, producing an almost pathognomonic groove sign for LGV. [atsu.edu]
Gastrointestinal
- Perianal Ulcer
All 14 women had ulcers; two (14%) had asymptomatic cervical ulcers that were found only on examination; six (43%) had only perianal ulcers; and the remaining six (43%) had symptomatic vulvar ulcers. Six of the women had tender inguinal adenopathy. [cdc.gov]
Skin
- Ulcer
All patients should return for review if their ulcers have not healed. [sti.guidelines.org.au]
Abstract Acute genital ulcers, also known as acute vulvar ulcers, ulcus vulvae acutum or Lipschütz ulcers, refer to an ulceration of the vulva or lower vagina of non-venereal origin that usually presents in young women, predominantly virgins. [ncbi.nlm.nih.gov]
Other names for vulval aphthosis include vulval aphthous ulcers, Lipschütz ulcer, Mikulicz ulcer, Sutton ulcer, and ulcus vulvae acutum. Vulval aphthosis is commonly associated with oral ulceration. [dermnetnz.org]
During 2000-2014, the percentage of genital ulcers caused by H. ducreyi was low ( 5 and North India with 24% of genital ulcer disease. 6 A recent report from Cuba described no infection with H. ducreyi in genital ulcer disease patients. 7 In the United [accessmedicine.mhmedical.com]
The time required for complete healing depends on the size of the ulcer; large ulcers might require greater than two weeks. In addition, healing is slower for some uncircumcised men who have ulcers under the foreskin. [dph.illinois.gov]
- Chancre
sexually transmitted disease chancroid, chancroid, chancroid (diagnosis), (Chancroid [& bubo]) or (Ducrey's chancre), (Chancroid [& bubo]) or (Ducrey's chancre) (disorder), Chancroidal bubo, Ducrey's chancre, Soft chancre - chancroid, Soft sore - chancroid [fpnotebook.com]
Sometimes, multiple chancres may be present. The chancre contains infectious bacteria and while the sore is present, the condition is highly contagious. Any contact with the chancre can spread the infection. [medicinenet.com]
Untreated, the primary chancre usually goes away within 4 weeks. There is often painless swelling of lymph glands during this stage. [sahealth.sa.gov.au]
- Skin Ulcer
Central ulceration and necrosis follow, leading to the characteristic chancre. In addition to genital ulcers, H. ducreyi causes chronic skin ulcerations, particularly in children from developing countries. [unboundmedicine.com]
Genital Ulcer Diseases Genital ulcers are skin ulcers on the genital area caused by sexually transmitted diseases or noninfectious conditions. [courses.lumenlearning.com]
The secondary stage involves the formation of subcutaneous granulomas in the inguinal area.( 3) Sometimes these lesions penetrate the skin, producing skin ulcers and become superinfected which may then lead to lymphadenopathy. [encognitive.com]
H ducreyi produces skin lesions in children that resemble ulcers associated with the tropical disease yaws. [1, 2] However, in adults, chancroid is characterized by the presence of painful ulcers (see image below) and inflammatory inguinal adenopathy. [emedicine.medscape.com]
- Skin Disease
Lonky: What skin diseases need to be ruled out before vulvodynia can be diagnosed? Dr. Edwards: Skin diseases that affect the vulva are usually pruritic—pain is a later sign. [mdedge.com]
Genetic diseases can present with chronic ulceration of vulval and perianal skin. Epidermolysis bullosa is a group of disorders that present with blistering in childhood. [dermnetnz.org]
Skin diseases of the vulva: Infectious diseases. J Obstet Gynaecol. 2017 Apr 11. 1-9. [QxMD MEDLINE Link]. Ducrey A. Experimentelle Untersuchungen uber den Ansteckungsstof des weichen Schankers und uber die Bubonen. [emedicine.medscape.com]
Neurologic
- Irritability
Spermicide in particular may be irritating enough to create microscopic cuts in sensitive genital skin, which can lead to irritation and increase your risk of STIs (the cuts provide easy entry points into your bloodstream). [refinery29.com]
Diagnosis Scabies may be confused with other skin irritations such as poison ivy or eczema. To make an accurate diagnosis, a doctor takes a scraping of the irritated area and examines it under a microscope, to reveal the presence of the mite. [wellness.illinoisstate.edu]
Vaginitis Vaginitis is usually characterized by a vaginal discharge or by vulvar itching and irritation; a vaginal odor may be present. [garyagenamd.com]
Dermatological conditions Nappy rash Nappy rash is an irritant contact dermatitis. [patient.info]
Symptoms of gonorrhea: abnormal bleeding a burning sensation during urination vaginal discharge general irritation of the outer area of the vagina Dyspareunia is the clinical name for painful intercourse. [worldoffemale.com]
Urogenital
- Chancroid
Chancroid Epidemiology Laboratory Diagnosis of Chancroid Treatment and Prevention of Chancroid Last Updated: Mar 21, 2019 Written by Dr. Tomislav Meštrović Dr. [news-medical.net]
Hemophilus ducreyi infection, Ulcus molle, Chancroid [Disease/Finding], ulcus molle, soft chancre, sexually transmitted disease chancroid, chancroid, chancroid (diagnosis), (Chancroid [& bubo]) or (Ducrey's chancre), (Chancroid [& bubo]) or (Ducrey's [fpnotebook.com]
"Chancroid." 5-Minute Clinical Consult, 27th ed., Wolters Kluwer, 2019. 5minute, www.unboundmedicine.com/5minute/view/5-Minute-Clinical-Consult/116121/all/Chancroid. Chancroid. [unboundmedicine.com]
[…] bacillus) causes chancroid. [emedicine.medscape.com]
- Dyspareunia
Causes of Dyspareunia Are Multiple The causes of dyspareunia, as with most sexual dysfunction, can be classified as either organic (physical or medical factors such as illness, injury or drug effects) or psychosocial (including psychological, interpersonal [worldoffemale.com]
[…] develop Buboes appear in about 50% of male patients The foreskin may swell The ulcers usually are found in: the prepuce near the frenulum coronal sulcus glans Rectal sores may bleed and or cause pain when defecating In women Buboes are uncommon in women Dyspareunia [mobieg.co.za]
Women generally have less specific symptoms such as painful urination or pain on passing bowel motions (defaecation), vaginal discharge, painful sexual intercourse ( dyspareunia ) and rectal bleeding. [dermnetnz.org]
Even though in some cases vulvar lesions may go undetected because they are asymptomatic, it is a general rule that a woman must have at least one symptom such as pruritus (itchy sensation), dysuria (painful urination) or dyspareunia (painful sexual intercourse [ic.steadyhealth.com]
There is only a single ulcer in most infected men and appears in coronal sulcus of the uncircumcised glans penis, whereas women frequently have four or more ulcers, characterized by dysuria (pain with urination) and dyspareunia (pain with intercourse) [zeenews.india.com]
- Syphilitic Chancre
A57 virulent A57 (chancroidal) Chancre (any genital site) (hard) (hunterian) (mixed) (primary) (seronegative) (seropositive) (syphilitic) A51.0 ICD-10-CM Diagnosis Code A51.0 Primary genital syphilis 2016 2017 2018 2019 Billable/Specific Code Applicable [icd10data.com]
The genital chancre of syphilis is clinically distinguished from that of chancroid in that the syphilitic ulcer is painless. Cultures on chocolate agar are used to confirm the diagnosis. [medical-dictionary.thefreedictionary.com]
Comparison with syphilis [ edit ] There are many differences and similarities between the conditions syphilitic chancre and chancroid. [en.wikipedia.org]
Chancroid is often referred to as a soft chancre because the lesions are usually not indurated. In contrast, a syphilitic chancre is nontender and indurated. [emedicine.medscape.com]
- Vulvar Pain
Chancroid is a painful vulvar ulcer. Trichomonas can sometimes be associated with vulvar pain. Dr. Lonky: What terminology do we use when we discuss vulvar pain? Dr. [mdedge.com]
Workup
Hence, it is important to know the workup and the thorough differential diagnosis to establish its diagnosis. [ncbi.nlm.nih.gov]
Microbiology
- Chlamydia
Skenitis Will need I&D Culture for GC, Chlamydia www.freelivedoctor.com 8. [slideshare.net]
Each year, over 4 million women are affected by chlamydia. The disease is caused by the bacterium Chlamydia trachomatis, found mainly in the cervix and urethra. Similar to gonorrhea, chlamydia can survive in the rectum or throat. [plushcare.com]
Chlamydia Chlamydia infection is a common sexually transmitted infection (STI) in humans caused by the bacterium Chlamydia trachomatis. [courses.lumenlearning.com]
Chlamydia What is chlamydia? Chlamydia ( Chlamydia trachomatis ) is a bacterium that causes an infection that is very similar to gonorrhea in the way that it is spread and the symptoms it produces. [medicinenet.com]
- Hemophilus Ducreyi
[…] chancre) (disorder), Chancroidal bubo, Ducrey's chancre, Soft chancre - chancroid, Soft sore - chancroid, Chancroid (disorder), Haemophilus ducreyi, Hemophilus ducreyi, bubo; Haemophilus ducreyi, bubo; Hemophilus ducreyi, bubo; chancroidal, bubo; soft [fpnotebook.com]
Hemophilus ducreyi, the causative organism, is difficult to culture, so the diagnosis is made on the basis of history, physical exam and exclusion of other ulcerative diseases of the vulva. [brooksidepress.org]
Convert to ICD-10-CM : 099.0 converts directly to: 2015/16 ICD-10-CM A57 Chancroid Applies To Bubo (inguinal): chancroidal due to Hemophilus ducreyi Chancre: Ducrey's simple soft Ulcus molle (cutis) (skin) ICD-9-CM Volume 2 Index entries containing back-references [icd9data.com]
Treatment
Principal Treatment Options Situation Recommended Alternative Uncomplicated infection Azithromycin 1g PO, stat OR Ceftriaxone 500mg in 2mL of 1% lignocaine IMI, stat OR Ciprofloxacin 500mg PO, BD for 3 days Alternative regimens are not recommended Treatment [sti.guidelines.org.au]
Condyloma Lata Treatment Same as Primary Syphilis www.freelivedoctor.com 23. [slideshare.net]
The book gives clinicians the necessary background information to educate patients on how these diseases are transmitted and acquired, what treatment options are available, what to expect from treatment, and how to prevent reinfection. [books.google.com]
What is the treatment for syphilis? For detailed treatment recommendations, please refer to the 2021 CDC STI Treatment Guidelines. [cdc.gov]
Low enough levels confirm adequate treatment. [medicalnewstoday.com]
Prognosis
Prognosis - Chancroid Prognosis is excellent with proper treatment. Treating sexual contacts of affected individual helps break cycle of infection. Resources - Chancroid Not supplied. [checkorphan.org]
Advances in the recognition of potentially confusing benign conditions, prognosis and staging update the pathology of squamous and adenocarcinoma in these organs. [books.google.de]
Etiology
Disease-oriented chapters include etiology, differential diagnosis, history, physical examination, laboratory and imaging studies, treatment, and special considerations during pregnancy. [books.google.com]
[…] superimposed Fusobacterium infection is present Do not confuse with chancre, a lesion typical of infection with syphilis Epidemiology Mainly in developing countries, particularly Africa, Asia and Latin America Associated with commercial sex workers Etiology [pathologyoutlines.com]
More common in Sub-Saharan Africa Southeast Asia Latin America Etiology and Pathophysiology Haemophilus ducreyi enters through abraded skin during sexual activity, attaching to susceptible cells. [unboundmedicine.com]
Epidemiology
Showing 1-10 of 51 references Sex, soap and antibiotics : the case for chancroid eradication Changing aetiology of genital ulcer disease ( GUD ) in STD clinic attenders with a rising HIV prevalence Epidemiological, clinical and microbiological features [pdfs.semanticscholar.org]
Lippincott Williams & Wilkins, 2003 - 275 من الصفحات This concise handbook provides the essential information that physicians and nurse practitioners need on the epidemiology, microbiology, diagnosis, management, and prevention of sexually transmitted [books.google.com]
[…] chancroid: may extend rapidly and be associated with ruptured inguinal abscess Phagedenic chancroid: may destroy external genitalia if superimposed Fusobacterium infection is present Do not confuse with chancre, a lesion typical of infection with syphilis Epidemiology [pathologyoutlines.com]
[…] sporadic cases, often misdiagnosed as genital herpes. 9, 10 The distinct decrease in prevalence has followed the introduction by the World Health Organization (WHO) of syndromic management for treating genital ulcer disease. 4 Nevertheless, the global epidemiology [accessmedicine.mhmedical.com]
Data Guidance Resources for Providers Testing Vaccine Information Treatment Media & Publications Frequently Asked Questions (FAQ) Data & Statistics Behavioral Risk Factor Surveillance System Database & Datafile Resources Guide EMS Data Reporting System Epidemiology [dph.illinois.gov]
Pathophysiology
More common in Sub-Saharan Africa Southeast Asia Latin America Etiology and Pathophysiology Haemophilus ducreyi enters through abraded skin during sexual activity, attaching to susceptible cells. [unboundmedicine.com]
Background, Pathophysiology, Epidemiology. N.p., 09 Feb. 2017. Web. 16 Apr. 2017. Last Updated: 16 January 2018. [soc.ucsb.edu]
See Pathophysiology. Chancroid is closely associated with prostitution. H ducreyi can survive only in subgroups of the population with a sufficient turnover of sex partners. [emedicine.medscape.com]
The pathophysiological mechanism of ulcer in these cases is unknown. [ncbi.nlm.nih.gov]
[…] the glans [ ] Placement of a preputial bead Erotic dancing [ ] P lasmodium falciparum infection [ ] Contact dermatitis (eg, from the application of celandine juice to the foreskin [ ] ) Haemophilus ducreyi infection ( chancroid ) [ ] Previous Next: Pathophysiology [tripdatabase.com]
Prevention
Some researchers have speculated that these products, designed for use prior to sexual intercourse to prevent infection, might also be used for postcoital or emergency STD prevention. [un.org]
Lippincott Williams & Wilkins, 2003 - 275 من الصفحات This concise handbook provides the essential information that physicians and nurse practitioners need on the epidemiology, microbiology, diagnosis, management, and prevention of sexually transmitted [books.google.com]
C 15, 16 Prevention Avoiding sexual intercourse during outbreaks does not prevent transmission of HSV infection. [aafp.org]
HIV prevention through early detection and treatment of other sexually transmitted diseases–United States. Recommendations of the Advisory Committee for HIV and STD prevention. MMWR Recomm Rep, 1998. 47(RR-12): p. 1-24. 8. [cdc.gov]