Presentation
Risk of bias in included studies Figure 2 presents a summary of the 'Risk of bias' assessments of the included studies by the review authors. [cochranelibrary.com]
Musculoskeletal
- Foot Deformity
Skeletal deformities like scoliosis or foot deformities can be additional features (Shy 2005b). [cochranelibrary.com]
Treatment
We assessed treatment effects by meta‐analysis of data using forest plots. We determined the overall treatment effect by the Z‐score. We considered a significance level of P < 0.05 as the threshold for statistically significant treatment effects. [cochranelibrary.com]
Congenital Myasthenic Syndromes: a Clinical and Treatment Approach. Current treatment options in neurology, 20(9), 36. https://doi.org/10.1007/s11940-018-0520-7 Rodríguez Cruz, P. M., Palace, J., & Beeson, D. (2018). [igenomix.es]
Etiology
Arthrogryposis (multiple congenital contractures): Diagnostic approach to etiology, classification, genetics, and general principles. European Journal of Medical Genetics, 57(8), 464-472. doi:10.1016/j.ejmg.2014.03.008 Solicitar información [igenomix.es]
Pathophysiology
Pathophysiology The pathophysiological mechanisms that lead to the clinical phenotype are still unclear for many of the genes implicated in CMT. [cochranelibrary.com]