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2.1
Chiasmal Syndrome
Disease (or Disorder) Chiasmal Optic

Images

WIKIDATA, Public Domain

Presentation

Traumatic chismal syndrome should be considered in the differential diagnosis of patients presenting with bitemporal hemianopsia. [ncbi.nlm.nih.gov]

Four months after the accident, he presented with a chief complaint of lateral blindness in the left eye. His best corrected visual acuity was 0.7 in the left eye and 1.0 in the right eye. [ijo.in]

In the presented case, the patient has had eight years of survival and his actual cardiac function is normal. [ijcasereportsandimages.com]

A review of the present literature and current understanding of the pathogenesis of this intriguing syndrome is presented. [thieme-connect.com]

Psychiatrical

  • Fear

    The supposed artifactual nature of Wilbrand's knee has implications for the degree of resection that can be obtained, namely by cutting the optic nerve immediately at the junction with the chiasm without fear of potentially resulting visual field deficits [en.wikipedia.org]

Neurologic

  • Bitemporal Hemianopsia

    Traumatic chismal syndrome should be considered in the differential diagnosis of patients presenting with bitemporal hemianopsia. [ncbi.nlm.nih.gov]

    Traumatic bitemporal hemianopsia and diabetes insipidus. Surg Neurol 09 1978; 246 [thieme-connect.com]

    Traumatic chiasmal syndrome presenting with bitemporal hemianopsia. J Trauma 1998;44:224-9. [ PUBMED ] [Figure 1], [Figure 2] Article Access Statistics Viewed 1932 Printed 20 Emailed 0 PDF Downloaded 115 Comments [Add] [ijo.in]

    hemianopsia due to traumatic chiasmal syndrome. ( 27135085 ) Yazici B....Kivanc S.A. 2016 5 Traumatic Chiasmal Syndrome: A Midline Axonal Injury. ( 27928365 ) Vora T.K....Ravi R.R. 2015 6 Early morphological recovery of the optic chiasm is associated [malacards.org]

  • Motor Disturbances

    Abstract The chiasmal syndrome has distinct ophthalmological features such as visual field loss, optic disc changes, decrease in visual acuity, ocular motor disturbances and exophthalmos. [ncbi.nlm.nih.gov]

Workup

Diagnosis and Workup The patient was diagnosed as a normal tension glaucoma suspect and subsequently referred to a glaucoma specialist for further evaluation and treatment. [reviewofophthalmology.com]

It is important to note that while a sellar mass may present with bitemporal hemianopia, the combination of findings described above describing a junctional scotoma also localizes to the sellar area, and additional workup is indicated. [webeye.ophth.uiowa.edu]

While a majority of patients with endogenous Cushing syndrome have thyrotrophic adenomas (called Cushing Disease - see below), other tumors should also be considered as part of the endocrinologic workup, including adrenal tumors and especially ACTH-secreting [eyewiki.aao.org]

It was obtained from a patient who reported visual loss and had a normal endocrine workup. The dark areas correspond to the impaired peripheral visual field. This visual field defect is consistent with an intrasellar lesion. [emedicine.medscape.com]

Treatment

Pituitary adenomas are the most common cause of an optic chiasmal syndrome, and treatment of these lesions is considerably different from the treatment of most of the other lesions in this region. [ncbi.nlm.nih.gov]

Purpose Pituitary adenomas are the most common cause of an optic chiasmal syndrome, and treatment of these lesions is considerably different from the treatment of most of the other lesions in this region. [jhu.pure.elsevier.com]

A review of recent and relevant literature was performed to highlight chiasmal syndromes and pathology, as well as to discuss current methods of diagnosis, prognosis and considerations in the treatment of a patient presenting with a chiasmal disorder. [uthealth.influuent.utsystem.edu]

Coverage includes major updates on genetics of diseases, new diagnostic techniques, and the newest treatment options. This third volume covers degenerative, metabolic, infectious, inflammatory, and demyelinating diseases. [books.google.com]

Prognosis

A review of recent and relevant literature was performed to highlight chiasmal syndromes and pathology, as well as to discuss current methods of diagnosis, prognosis and considerations in the treatment of a patient presenting with a chiasmal disorder. [uthealth.influuent.utsystem.edu]

Patients with an optic glioma and neurofibromatosis type 1 have a better prognosis than those who do not have neurofibromatosis. [thamburaj.com]

The clinical manifestations, neuro-imaging results, and visual prognosis were evaluated in each patient. [e-tjo.org]

It's unclear if the natural history and final prognosis of FA is modified by cardiac transplantation. We have been able to perform a longer follow up than the other reports. [ijcasereportsandimages.com]

Boys without diencephalic syndrome had a better prognosis (HR: 0.3 [95% CI: 0.1-0.8], p=0.007). [journals.plos.org]

Etiology

Although no single clinical feature can be used to determine the specific nature of a lesion that produces an optic chiasmal syndrome, certain features are highly suggestive of an etiology other than pituitary adenoma. [ncbi.nlm.nih.gov]

Conclusion Although no single clinical feature can be used to determine the specific nature of a lesion that produces an optic chiasmal syndrome, certain features are highly suggestive of an etiology other than pituitary adenoma. [jhu.pure.elsevier.com]

Intrinsic etiologies include gliomas and multiple sclerosis. Gliomas of the optic chiasm are usually derived from astrocytes. These tumors are slow growing and more often found children 4. [wikidoc.org]

Epidemiology

Figure 7 : Non-contrast head CT, axial view, showing layered hemorrhages within bilateral lateral ventricles Diagnosis Compressive optic neuropathy/junctional scotoma secondary to pituitary adenoma EPIDEMIOLOGY Age and gender predilection varies depending [webeye.ophth.uiowa.edu]

Epidemiology INCIDENCE  1% of all intracranial tumours, 3–5% of paediatric brain tumours and 6% of all orbital tumours.  Gliomas account for two-thirds of all tumours in the optic nerve.  About 25% of OPGs are in the optic nerve [Optic nerve glioma [slideshare.net]

[PUBMED Abstract] Milano MT, Johnson MD, Sul J, et al.: Primary spinal cord glioma: a Surveillance, Epidemiology, and End Results database study. J Neurooncol 98 (1): 83-92, 2010. [cancer.gov]

[…] less commonly patients may also have Ocular motility deficits and/or Diplopia, certain forms of Nystagmus, signs and symptoms of Increased intracranial pressure due to mass effect, Optic atrophy, or sequelae of Pituitary apoplexy. [3] [4] [5] General Epidemiology [eyewiki.aao.org]

Pathophysiology

The pathophysiology of neurological disorders in childhood is based on the same principles of the organization, structure, and function of the nervous sys tem as apply to adults. Two pitfalls are present for the student, however. [books.google.com]

Delayed visual deterioration after pituitary surgery has been attributed to secondary empty sella syndrome and downward herniation of the optic nerves and chiasm, but the pathophysiological basis of this condition is still a matter of debate. [scinapse.io]

It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. [books.google.ro]

It is of clinical, pathophysiologic, and occasionally therapeutic importance to distinguish those cases occurring without an identifiable cause ("primary" empty sella) from those arising as the result of loss of intrasellar volume, which may accompany [78stepshealth.us]

Prevention

Clinicians should be aware of Sneddon syndrome because prompt diagnosis and treatment may prevent potential morbidity and mortality. [collections.lib.utah.edu]

As the pituitary tumour causes compression of the optic chiasm, tumour reduction or removal is important to prevent progressive field loss. [mrcophth.com]

Treatment of carpal tunnel syndrome Lock your wrist and pad from a roller as a preventive measure removes the burden on the median nerve and ligaments in the wrist. [minclinic.ru]

The secondary objective was to review complications of transsphenoidal surgery from the standpoint of their causation, treatment, and prevention. [scinapse.io]

However, in several cases, enteral or parenteral nutrition may provide to children unable to feed the nutrients necessary to ensure proper growth, to correct or prevent malnutrition [ 22 ]. [bmccancer.biomedcentral.com]

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