Given the wide variety of presentations, chikungunya fever-related uveitis should be included in the differential diagnosis of all at-risk patients presenting with acute ocular inflammation, particularly those traveling from endemic regions. [ncbi.nlm.nih.gov]

• Fever

  Chikungunya and dengue fevers The clinical manifestations of chikungunya fever have to be distinguished from dengue fever. [web.archive.org]

  Of 652 patients included in the surveillance of yellow fever in DRC from January 2003 to January 2012, 453 patients that tested negative for yellow fever virus (YFV) immunoglobulin M (IgM) antibodies were selected for the study. [ncbi.nlm.nih.gov]

  Because CHIK fever epidemics are sustained by human-mosquito-human transmission, the epidemic cycle is similar to those of dengue and urban yellow fever. [cdc.gov]

• Chills

  The initial manifestations of this virus are sudden onset high fever, headache, chills, rashes, myalgia and intense joint pain. [ncbi.nlm.nih.gov]

  It comes on like the flu — fever, chills, headache, aching joints — and typically lingers for a week. Many patients later develop severe joint pain that can recur for months or years. [sciencenews.org]

  Symptoms It is generally characterized by abrupt onset of fever, chills which is accompanied by joint pain. [aimu.us]

  Fever, chills, headache and muscle pain. Joint swelling, stiffness and pain, especially in the mornings. A rash, usually on the trunk or limbs. This usually lasts for 7 - 10 days. A feeling of tiredness or weakness. [health.nsw.gov.au]

  Other symptoms like chills, headache, fatigue, abdominal pain, nausea, vomiting, diarrhea, reduced appetite and conjunctivitis can also be seen. Rash occurs typically on day 2 or 3 when the fever has subsided along with itching. [goqii.com]

• Malaise

  He had onset of illness hours after arrival in the United States, including fever, headache, malaise, and joint pain mainly in a shoulder and a knee. [web.archive.org]

  Both infections have similar symptoms, including fever, malaise and fatigue. [pharmaceutical-journal.com]

  […] and FDA on the Safety of Gardasil Vaccine". supplement to your biologics license application (BLA) for Human Papillomavirus Quadrivalent (Types 6, 11, 16 and 18) Vaccine, Recombinant (GARDASIL), to include arthralgia, myalgia, asthenia, fatigue, and malaise [en.wikipedia.org]

  Material and Methods Study Population Subjects were 1835 individuals with suspicious diagnosis of arbovirus infection, defined by fever (≥38 °C), exanthemata, headache, retro-orbital pain, photophobia, lumbar back pain, chills, weakness, malaise, nausea [nature.com]

• Recurrent Inflammation

  This is the first reported case of recurrent inflammation. [ncbi.nlm.nih.gov]

• Plethora

  A plethora of ocular manifestations have been described ranging from a non-specific conjunctivitis to exudative retinal detachment. Ocular chikungunya seems to respond well to corticosteroid therapy, and outcomes are usually better if treated early. [ncbi.nlm.nih.gov]

• Bleeding Gums

  Some cases brought on nosebleeds and bleeding gums. While joint and muscle pain may continue, there are few other long-term effects. These symptoms can sometimes last for months or years after infection. [passporthealthusa.com]

  gums (uncommon) Symptoms of chikungunya can be severe and disabling in some people. [emedicinehealth.com]

  Haemorrhagic manifestations (petechiae, purpura, bleeding gums, nosebleeds, haematemesis, and melena) Footnote 1 have been documented, but only in Asia Footnote 10. [phac-aspc.gc.ca]

  Bleeding gums and nosebleeds have often been described in connection with the disease, mainly in Asia. [pasteur.fr]

• Scotoma

  At 5-month follow-up, there was a persistent right RAPD and marked optic atrophy with a corresponding inferior scotoma in the visual field. [ncbi.nlm.nih.gov]

• Arthralgia

  OBJECTIVE: We present a case of Chikungunya virus (CHIKV)-induced arthritis and review the literature surrounding Chikungunya-induced arthritis/arthralgias and associated musculoskeletal (MSK) manifestations. [ncbi.nlm.nih.gov]

  The crippling arthralgia and frequent arthritis that accompany the fever and other systemic symptoms are clinically distinct. [vadscorner.com]

  These two patients were positive for anti-CHIKV IgG but did not suffer from chronic arthralgia. [doi.org]

• Symmetrical Arthritis

  They had morning stiffness in and around the joints lasting 1 h before maximal improvement, arthritis of three or more joint areas in the 14 possible joint areas specified in ACR criteria, arthritis of hand joints and symmetric arthritis. 21 3.9 The erythrocyte [doi.org]

• Oligoarthritis

  Among these, 188 patients had polyarthritis and 10 patients had oligoarthritis. Out of 203 subjects, 9 subjects had pre-existing intermittent headache and 14 had pre-existing joint pain. [doi.org]

• Skin Rash

  In Chikungunya mostly symptoms have an abrupt onset with high grade fever, single or multiple joint pains, skin rashes, headache and myalgia. [vikaspedia.in]

  Chikungunya fever is a vector borne virus that typically causes a self-limiting systemic illness with fever, skin rash and joint aches 2 weeks after infection. [ncbi.nlm.nih.gov]

  Homepage Rare diseases Search Search for a rare disease Chikungunya Disease definition A rare infectious disease characterized by acute onset of high fever associated with debilitating polyarthralgia and usually accompanied by an erythematous skin rash [orpha.net]

  Skin rashes Rashes on trunk, limbs, face, palms and feet. Rashes usually limited to face and limbs. Possible complications Upto 10% of patients develop chronic joint pain. Neurological damage is possible, but rare. [chikungunya.in]

• Maculopapular Skin Rash

  During the second to fifth day of illness, a papular or maculopapular skin rash may occur, typically on the trunk and limbs. Most patients recover within a few days. Arthralgias may last several months. [lionel.suz.free.fr]

• Facial Swelling

  The same for facial swelling, swelling around the joint, limb swelling, and rash was day 2, 2, 3 and 4 respectively. [doi.org]

• Headache

  But it causes a high fever, headache, nausea and extreme joint pain — which can linger for months. And there's no cure or vaccine. [web.archive.org]

  Initial Symptoms Fever, joint pain, muscle pain, headache, eye infection, rashes Fever, joint pain, headache, rashes Joint pain and muscle pain Joint pains on hands and feet. Swelling is present and the pain is high in the morning. [chikungunya.in]

  Myalgia, severe headache, and lymphadenopathy are frequently associated. Chronically the disease may cause recurrent, long-term polyarthralgia, arthritis, fatigue, and depression. [orpha.net]

  A rash, headache, fatigue, nausea and muscle pains may also occur. The illness usually resolves over a few days and serious complications are uncommon. [fitfortravel.nhs.uk]

• Limb Weakness

  Infection of humans by CHIKV can cause a syndrome characterized by fever, headache, rash, nausea, vomiting, myalgia, arthralgia and occasionally neurological manifestations such as acute limb weakness. [ncbi.nlm.nih.gov]

  The symptoms resolve over a period of time ranging from days to years. 5, 6 Presentations such as meningoencephalitis and flaccid limb weakness are deviations from the classical clinical features. 7, 8 Although there are studies on the frequency of occurrence [doi.org]

• Dysarthria

  Here we report a case of post chikungunya reversible demyelinating encephalitis who presented with vertigo, dysarthria and ataxia. There was complete clinical as well as radiological improvement with steroids. [ncbi.nlm.nih.gov]

Following a broad workup that included laboratory testing for dengue and malaria, our patient was diagnosed with Chikungunya virus, which was then reported to the Centers for Disease Control and Prevention for initiation of infection control. [ncbi.nlm.nih.gov]

Patients with persistent arthralgia should be referred to a rheumatologist for additional workup and treatment [14]. See smartphone apps to check your skin. [Sponsored content] Related information References Staples JE, Breiman RF, Powers AM. [dermnetnz.org]

Treatment of chikungunya arthritis usually involves non-steroidal anti-inflammatory drugs. [ncbi.nlm.nih.gov]

Evidence-based recommendations are needed to help physicians manage the treatment of afflicted patients. [doi.org]

Management There is no specific treatment for chikungunya. Only supportive treatment is given to ease the symptoms Administration of non-steroidal anti-inflammatory drugs help in relieving pain. [aimu.us]

This could possibly correlate with a prognosis, in terms of fever duration, possibility for chronic joint pain, and infectiousness to mosquitoes. [bcm.edu]

What should you tell the family about the patient’s prognosis? The overall prognosis with chikungunya fever is good. Mortality and complication rate is relatively low except in the elderly with multiple co-morbid conditions. [infectiousdiseaseadvisor.com]

Such good prognosis as seen in the aforementioned cases may not be representative of the true clinical progression, and may be biased due to the early age of the patients 28. [f1000research.com]

What Is the Prognosis for a Chikungunya Virus Infection? In general, chikungunya virus is self-limiting, and most cases resolve on their own in seven to 10 days. After effects may include joint pain ( arthritis ) that persists. [emedicinehealth.com]

[…] infection of neonates born to viremic mothers and exposed to the virus during birth can reach 50%, leading to severe disease and encephalopathy, resulting in long-term neurological sequelae and poor outcome. 62 In general, CHIKV infection has a good prognosis [elsevier.es]

Search terms included Chikungunya virus, etiology, and fever. Searches were limited to humans and English language publications. Additional relevant articles were obtained from the reference lists. © 2013 Elsevier Inc. All rights reserved. [ncbi.nlm.nih.gov]

University of Oklahoma Study Abroad Microbiology in Arezzo, Italy [1] Etiology/Virology Baltimore Classification Group IV: (+) ssRNA Virus ICTV Classification Family |= Togaviridae Genus |= Alphavirus Species |= Chikungunya Virus Description By classification [microbewiki.kenyon.edu]

Overall, 57% of participants tested positive by IgM for one of these seven etiological agents. [doi.org]

Report for 2017 Publication Communicable disease threats report, 17-23 March 2019, week 12 News Health risks during the Carnival season in Brazil News Epidemiological update: Chikungunya – Europe - 2017 News Epidemiological update: Chikungunya – Europe [ecdc.europa.eu]

The present era of international travel poses a new diagnostic and epidemiologic challenge that demands increased awareness to the possibility of an exotic tropical infectious disease. [ncbi.nlm.nih.gov]

The possible pathophysiology of chikungunya virus causing ANSD and vestibular symptoms needs to be explored further in future studies. [ncbi.nlm.nih.gov]

BMC Infectious Diseases is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of infectious and sexually transmitted diseases in humans, as well as related molecular genetics, pathophysiology [biomedcentral.com]

Original Editors - Kristin Dierker & Kalie Reams from Bellarmine University's Pathophysiology of Complex Patient Problems project. [physio-pedia.com]

The pathophysiology of human CHIKV infection has long been a mystery. Some hypotheses were first proposed based on data from other alphaviruses. [doi.org]

[…] staying in the affected areas in order to prevent becoming infected with the virus. [ecdc.europa.eu]

Prevention and control No vaccine is available against this virus infection. Prevention is entirely dependent upon taking steps to avoid mosquito bites and elimination of mosquito breeding sites. [web.archive.org]

Prevention At present, there is no effective vaccine against chikungunya fever. Prevention and control relies heavily on reducing the number of natural and artificial water-filled container habitats that support breeding of the mosquitoes. [chp.gov.hk]